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anticholinergics use and symptoms of dementia in young adults

W G Sannita, L Maggi, G Rosadini
There has been clinical and experimental evidence that cholinergic compounds and precursors of choline are potentially useful in the treatment of dementia. Anticholinergic compounds have also been proposed as a possible acute model for pharmaco-EEG studies focussed on CNS aging. Single doses of scopolamine (0.25-0.75 mg i.m.) and a matching placebo were administered to 8 young healthy volunteers. Quantitative EEG recordings and neuropsychological testing were performed in baseline conditions prior to and 30, 90 and 120 min after drug administration...
1987: Neuropsychobiology
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