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neuropsychological assessment in pain management

S Palermo, I Rainero, M Stanziano, L Vase, F D'Agata, E Rubino, M C Valentini, P Fonio, F Sardanelli, M Amanzio
Neural correlates of placebo analgesia (PA) in patients with neurocognitive disorders have not yet been elucidated. The present study aimed to evaluate how and to what extent executive (dys)functions of the medial prefrontal cortex (MPFC) may be related to PA. To this end, twenty-three subjects complaining of different cognitive deficits (from mild cognitive impairment likely due to Alzheimer's Disease to mild AD) were recruited. PA was investigated by a well-known experimental venipuncture pain paradigm (open versus hidden, O-H, application of lidocaine)...
January 15, 2019: Experimental Gerontology
Katie Veretennikoff, Terry Coyne, Vivien Biggs, Gail A Robinson
Intracranial epidermoid cysts are rare, comprising 0.2% to 1.8% of all primary intracranial expanding lesions, of which <5% occur within the fourth ventricle. Epidermoid cysts are frequently congenital, and patients often present in the fourth decade of life. These cysts produce symptoms as a result of mass effect on surrounding structures, most commonly the cerebellum and cranial nerves. Symptoms can include hearing impairment, trigeminal neuralgia (severe facial pain), facial tics, headaches, double vision, and facial palsy...
December 2018: Cognitive and Behavioral Neurology: Official Journal of the Society for Behavioral and Cognitive Neurology
R M Schiller, K Allegaert, Maayke Hunfeld, G E van den Bosch, John van den Anker, D Tibboel
Inadequate pain and/or stress management in preterm- and term-born infants has been associated with increased morbidity and even mortality. However, exposure to analgosedatives during early infancy may also be one of the risk factors for subsequent neurodevelopmental impairment, at least in animal studies. Because infants admitted to neonatal or pediatric intensive care units may receive high amounts of these drugs for prolonged periods of time and the majority of these infants nowadays survive to discharge, this is of major concern...
October 2018: Journal of Clinical Pharmacology
Ciaran M Considine, Hillary A Parker, Jeralee Briggs, Erin E Quasney, Eric R Larson, Heather Smith, Skyler G Shollenbarger, Christopher A Abeare
OBJECTIVES: Obstructive sleep apnea (OSA) is associated with cognitive impairment but the relationships between specific biomarkers and neurocognitive domains remain unclear. The present study examined the influence of common health comorbidities on these relationships. Adults with suspected OSA (N=60; 53% male; M age=52 years; SD=14) underwent neuropsychological evaluation before baseline polysomnography (PSG). Apneic syndrome severity, hypoxic strain, and sleep architecture disturbance were assessed through PSG...
September 2018: Journal of the International Neuropsychological Society: JINS
Krister W Fjermestad, Livø Nyhus, Øivind J Kanavin, Arvid Heiberg, Lise B Hoxmark
Neurofibromatosis type 1 (NF1) is a genetic, autosomal dominant multi-organ disease characterized by susceptibility to tumor formation, changes in skin pigmentation, skeletal abnormalities, and neuropsychological deficits. Clinical studies have shown impaired health-related quality of life (HQoL) in adults with NF1. However, little is known about HQoL in non-clinical NF1 samples. We conducted a cross-sectional self-report survey of 142 persons with NF1 (M age = 50.3 years, SD = 12.0, range 32 to 80; 62...
September 2018: Journal of Genetic Counseling
Gauri Ghate, Eric Clark, Christian Vaillancourt
OBJECTIVES: The aim of the study is to determine the performance of low-dose ketamine (LDK) as an analgesic for acute pain management in adult patients in the emergency department (ED). METHODS: We systematically reviewed electronic databases, grey literature, conference abstracts, and clinical trial registries. Two independent reviewers identified eligible studies. These selections were subsequently reviewed by one reviewer who identified the final eligible studies, using refined inclusion and exclusion criteria...
January 2018: CJEM
Mathilde Carlsberg, Jean-Michel Mazaux, Laurent Wiart, Emmanuelle Coste, Michèle Koleck, Audrey Simion, Véronique Soriano
OBJECTIVE: The causes responsible for a brain injuries are various. Whatever its origin (traumatic, vascular, tumor or anoxic), the after effects lead to a chronic disability that affects durably the quality of life (QOL) of brain injured patients but also the strategies in place to cope with the difficulties they face (coping). The objective of this study is to compare the quality of life and the coping strategies between patients with a traumatic brain injury and with those with other type of brain injuries...
September 2016: Annals of Physical and Rehabilitation Medicine
Shirley Thomas, Declan Walsh, Aynur Aktas
INTRODUCTION: Patient-reported outcomes are an integral part of modern healthcare. We report a comparison of symptom item content from several validated cancer instruments to that of a published checklist, and identify the important differences this revealed. METHODS: We defined orphans as any symptom not assessed in any of the six selected instruments; champions, in contrast, were present in all six. An empirically derived cancer multisymptom checklist was used...
December 23, 2015: BMJ Supportive & Palliative Care
Albert Leung, Shivshil Shukla, Amir Fallah, David Song, Lisa Lin, Shahrokh Golshan, Alice Tsai, Amy Jak, Greg Polston, Roland Lee
OBJECTIVE: Headache is one of the most common debilitating chronic pain conditions in either active or retired military personnel with mild traumatic brain injury (MTBI). This study assessed the effect of repetitive transcranial magnetic stimulation (rTMS) in alleviating MTBI-related headache (MTBI-HA). MATERIALS AND METHOD: Veterans with MTBI-HA were randomized to receive either real rTMS (REAL group) at 10 hz for a total of 2000 pulses divided into 20 trains with one-sec inter-train interval or sham rTMS (SHAM group) at the left motor cortex (LMC) with brain magnetic resonance imaging neuronavigation guidance...
February 2016: Neuromodulation: Journal of the International Neuromodulation Society
Phillip D Fletcher, Laura E Downey, Hannah L Golden, Camilla N Clark, Catherine F Slattery, Ross W Paterson, Jonathan D Rohrer, Jonathan M Schott, Martin N Rossor, Jason D Warren
Symptoms suggesting altered processing of pain and temperature have been described in dementia diseases and may contribute importantly to clinical phenotypes, particularly in the frontotemporal lobar degeneration spectrum, but the basis for these symptoms has not been characterized in detail. Here we analysed pain and temperature symptoms using a semi-structured caregiver questionnaire recording altered behavioural responsiveness to pain or temperature for a cohort of patients with frontotemporal lobar degeneration (n = 58, 25 female, aged 52-84 years, representing the major clinical syndromes and representative pathogenic mutations in the C9orf72 and MAPT genes) and a comparison cohort of patients with amnestic Alzheimer's disease (n = 20, eight female, aged 53-74 years)...
November 2015: Brain: a Journal of Neurology
Lara Dhingra, Ebtesam Ahmed, Jae Shin, Elyssa Scharaga, Maximilian Magun
OBJECTIVE: Cognitive effects and sedation (CES) are prevalent in chronic nonmalignant pain populations receiving long-term opioid therapy and are among the most common reasons patients discontinue opioid use. In this narrative review, we describe the phenomenology, epidemiology, mechanisms, assessment, and management of opioid-related CES. DESIGN: We reviewed the empirical and theoretical literature on CES in opioid-treated populations with chronic pain. Data on long-term opioid therapy (≥ 3 months in duration) in chronic nonmalignant pain patients were sought...
October 2015: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
Mary M Vargo, Kevin G Vargo, Douglas Gunzler, Kermit W Fox
OBJECTIVE: To assess the frequency and spectrum of referrals to rehabilitation disciplines in a concussion clinic population and factors associated with need for referral. DESIGN: Retrospective study. SETTING: Concussion clinic within the Physical Medicine and Rehabilitation Department of an academic medical center. PARTICIPANTS: Patients receiving physiatric management for concussion care. MAIN OUTCOME MEASURES: Referral to physical therapy (PT), occupational therapy, speech therapy (ST), neuropsychology, or any referral (Any), and reasons for referral...
March 2016: PM & R: the Journal of Injury, Function, and Rehabilitation
Nina Attridge, Geert Crombez, Dimitri Van Ryckeghem, Edmund Keogh, Christopher Eccleston
Patients with chronic pain often report their cognition to be impaired by pain, and this observation has been supported by numerous studies measuring the effects of pain on cognitive task performance. Furthermore, cognitive intrusion by pain has been identified as one of 3 components of pain anxiety, alongside general distress and fear of pain. Although cognitive intrusion is a critical characteristic of pain, no specific measure designed to capture its effects exists. In 3 studies, we describe the initial development and validation of a new measure of pain interruption: the Experience of Cognitive Intrusion of Pain (ECIP) scale...
October 2015: Pain
Iris Coppieters, Kelly Ickmans, Barbara Cagnie, Jo Nijs, Robby De Pauw, Suzie Noten, Mira Meeus
BACKGROUND: A growing body of research has demonstrated that impaired central pain modulation or central sensitization (CS) is a crucial mechanism for the development of persistent pain in chronic whiplash-associated disorders (WAD) and fibromyalgia (FM) patients. Furthermore, there is increasing evidence for cognitive dysfunctions among these patients. In addition, chronic WAD and FM patients often report problems with health-related quality of life (QoL). Yet, there is limited research concerning the interrelations between cognitive performance, indices of CS, and health-related QoL in these patients...
May 2015: Pain Physician
Janine van Kooten, Suzanne Delwel, Tarik T Binnekade, Martin Smalbrugge, Johannes C van der Wouden, Roberto S G M Perez, Didi Rhebergen, Wouter W A Zuurmond, Max L Stek, Frank Lobbezoo, Cees M P M Hertogh, Erik J A Scherder
BACKGROUND: Pain is a common problem in people with dementia, however the exact prevalence of pain in dementia subtypes, e.g. Alzheimer's Disease (AD), Vascular Dementia (VaD), Frontotemporal Dementia (FTD) and dementia with Lewy Bodies (DLB), is unknown, as is the relation between pain and the different subtypes of dementia. In this study, the prevalence of pain in people with dementia will be investigated per dementia subtype and the relationship between the various subtypes of dementia and the presence of specific types of pain (i...
March 21, 2015: BMC Geriatrics
Claudia M Campbell, Luis F Buenaver, Srinivasa N Raja, Kasey B Kiley, Lauren J Swedberg, Paul W Wacnik, Steven P Cohen, Michael A Erdek, Kayode A Williams, Paul J Christo
OBJECTIVE: Spinal cord stimulation (SCS) has become a widely used treatment option for a variety of pain conditions. Substantial variability exists in the degree of benefit obtained from SCS and patient selection is a topic of expanding interest and importance. However, few studies have examined the potential benefits of dynamic quantitative sensory testing (QST) to develop objective measures of SCS outcomes or as a predictive tool to help patient selection. Psychological characteristics have been shown to play an important role in shaping individual differences in the pain experience and may aid in predicting responses to SCS...
July 2015: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
Elizabeth L Sampson, Nicola White, Kathryn Lord, Baptiste Leurent, Victoria Vickerstaff, Sharon Scott, Louise Jones
Pain is underdetected and undertreated in people with dementia. We aimed to investigate the prevalence of pain in people with dementia admitted to general hospitals and explore the association between pain and behavioural and psychiatric symptoms of dementia (BPSD). We conducted a longitudinal cohort study of 230 people, aged above 70, with dementia and unplanned medical admissions to 2 UK hospitals. Participants were assessed at baseline and every 4 days for self-reported pain (yes/no question and FACES scale) and observed pain (Pain Assessment in Advanced Dementia scale [PAINAD]) at movement and at rest, for agitation (Cohen-Mansfield Agitating Inventory [CMAI]) and BPSD (Behavioural Pathology in Alzheimer Disease Scale [BEHAVE-AD])...
April 2015: Pain
Tonya M Palermo, Emily F Law, Chuan Zhou, Amy Lewandowski Holley, Deirdre Logan, Gabrielle Tai
Although pain and function improve at immediate posttreatment for youth receiving cognitive behavioral therapy for chronic pain, limited data are available to understand changes that youth make during psychological treatment. We sought to characterize distinct trajectory patterns of change in pain and function to understand the temporal association of these changes during internet-delivered cognitive behavioral therapy (CBT). Weekly repeated assessments of pain and function were conducted during 8 weeks of treatment among 135 adolescents, aged 11 to 17 years, with chronic pain who were randomized to the cognitive behavioral intervention arm of an ongoing trial of internet-delivered CBT (Web-based management of adolescent pain; Web-MAP2)...
April 2015: Pain
Kevin J Bianchini, Luis E Aguerrevere, Brian J Guise, Jonathan S Ord, Joseph L Etherton, John E Meyers, R Denis Soignier, Kevin W Greve, Kelly L Curtis, Joy Bui
The Modified Somatic Perception Questionnaire (MSPQ) and the Pain Disability Index (PDI) are both popular clinical screening instruments in general orthopedic, rheumatologic, and neurosurgical clinics and are useful for identifying pain patients whose physical symptom presentations and disability may be non-organic. Previous studies found both to accurately detect malingered pain presentations; however, the generalizability of these results is not clear. This study used a criterion groups validation design (retrospective cohort of patients with chronic pain, n = 328) with a simulator group (college students, n = 98) to determine the accuracy of the MSPQ and PDI in detecting Malingered Pain Related Disability...
2014: Clinical Neuropsychologist
Katherine Webber, Andrew N Davies, Giovambattista Zeppetella, Martin R Cowie
CONTEXT: The successful management of breakthrough pain depends on a combination of adequate assessment, appropriate (individualized) treatment, and adequate re-assessment. Currently, there is no fully validated clinical assessment tool for breakthrough pain in cancer patients. OBJECTIVES: The aim of this project was to develop and validate a breakthrough pain assessment tool (the BAT) for use in the clinical setting. METHODS: The content of the BAT was determined by reviewing the medical literature, conducting a Delphi process with experts in breakthrough pain and/or pain assessment and conducting semi-structured interviews with cancer patients with breakthrough pain...
October 2014: Journal of Pain and Symptom Management
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