Tae-Houn Kim, Felix Hauser, Tracy Ha, Shaowu Xue, Maik Böhmer, Noriyuki Nishimura, Shintaro Munemasa, Katharine Hubbard, Nora Peine, Byeong-Ha Lee, Stephen Lee, Nadia Robert, Jane E Parker, Julian I Schroeder
Coordinated regulation of protection mechanisms against environmental abiotic stress and pathogen attack is essential for plant adaptation and survival. Initial abiotic stress can interfere with disease-resistance signaling [1-6]. Conversely, initial plant immune signaling may interrupt subsequent abscisic acid (ABA) signal transduction [7, 8]. However, the processes involved in this crosstalk between these signaling networks have not been determined. By screening a 9600-compound chemical library, we identified a small molecule [5-(3,4-dichlorophenyl)furan-2-yl]-piperidine-1-ylmethanethione (DFPM) that rapidly downregulates ABA-dependent gene expression and also inhibits ABA-induced stomatal closure...
June 7, 2011: Current Biology: CB