keyword
https://read.qxmd.com/read/38535110/left-ventricular-diastolic-dysfunction-is-associated-with-poor-functional-outcomes-after-endovascular-thrombectomy
#1
JOURNAL ARTICLE
Tony Y W Li, Emma M S Toh, Ying Ying Koh, Aloysius S T Leow, Bernard P L Chan, Hock-Luen Teoh, Raymond C S Seet, Anil Gopinathan, Cunli Yang, Vijay K Sharma, Leonard L L Yeo, Mark Y Chan, William K F Kong, Kian-Keong Poh, Benjamin Y Q Tan, Ching-Hui Sia
INTRODUCTION: With the advent of endovascular thrombectomy (ET), patients with acute ischaemic strokes (AIS) with large vessel occlusion (LVO) have seen vast improvements in treatment outcomes. Left ventricular diastolic dysfunction (LVDD) has been shown to herald poorer prognosis in conditions such as myocardial infarction. However, whether LVDD is related to functional recovery and outcomes in ischaemic stroke remains unclear. We studied LVDD for possible relation with clinical outcomes in patients with LVO AIS who underwent ET...
March 5, 2024: Journal of Cardiovascular Development and Disease
https://read.qxmd.com/read/38534473/a-comparison-of-the-impact-of-pharmacological-treatments-on-cardioversion-rate-control-and-mortality-in-data-driven-atrial-fibrillation-phenotypes-in-critical-care
#2
JOURNAL ARTICLE
Alexander Lacki, Antonio Martinez-Millana
Critical care physicians are commonly faced with patients exhibiting atrial fibrillation (AF), a cardiac arrhythmia with multifaceted origins. Recent investigations shed light on the heterogeneity among AF patients by uncovering unique AF phenotypes, characterized by differing treatment strategies and clinical outcomes. In this retrospective study encompassing 9401 AF patients in an intensive care cohort, we sought to identify differences in average treatment effects (ATEs) across different patient groups. We extract data from the MIMIC-III database, use hierarchical agglomerative clustering to identify patients' phenotypes, and assign them to treatment groups based on their initial drug administration during AF episodes...
February 20, 2024: Bioengineering
https://read.qxmd.com/read/38533983/risk-of-death-and-cardiovascular-events-in-asian-patients-with-atrial-fibrillation-and-chronic-obstructive-pulmonary-disease-a-report-from-the-prospective-aphrs-registry
#3
JOURNAL ARTICLE
Tommaso Bucci, Giulio Francesco Romiti, Alena Shantsila, Wee-Siong Teo, Hyung-Wook Park, Wataru Shimizu, Bernadette Corica, Marco Proietti, Hung-Fat Tse, Tze-Fan Chao, Frederick Frost, Gregory Y H Lip
BACKGROUND: Chronic obstructive pulmonary disease (COPD) is associated with an increased risk of adverse events in patients with atrial fibrillation (AF); however, few data are available on this topic in Asian populations. METHODS AND RESULTS: Prospective observational study conducted on patients with AF enrolled in the Asia-Pacific Heart Rhythm Society (APHRS) AF Registry. The diagnosis of COPD was based on data reported in the case report form by the investigators...
March 27, 2024: Journal of the American Heart Association
https://read.qxmd.com/read/38533848/atrial-fibrillation-comorbidities-stroke-and-mortality-in-real-world-clinical-practice
#4
JOURNAL ARTICLE
Giuseppe Boriani, Davide A Mei, Jacopo F Imberti
No abstract text is available yet for this article.
March 27, 2024: Polish Archives of Internal Medicine
https://read.qxmd.com/read/38530687/the-natural-history-of-atrial-functional-mitral-regurgitation
#5
JOURNAL ARTICLE
Jwan A Naser, Francisco B Alexandrino, Tomonari Harada, Hector I Michelena, Barry A Borlaug, Mackram F Eleid, Grace Lin, Christopher Scott, Austin M Kennedy, Patricia A Pellikka, Vuyisile T Nkomo, Sorin V Pislaru
BACKGROUND: The natural history of moderate/severe atrial functional mitral regurgitation (AFMR) is unknown. OBJECTIVES: The authors sought to study the incidence of left ventricular (LV) systolic dysfunction (LVSD), progression or regression of ≥mild-moderate AFMR, and impact on mortality. METHODS: Adults with left atrial (LA) volume index ≥40 mL/m2 , ≥mild-moderate AFMR, and follow-up echocardiogram were followed for incident LVSD (ejection fraction <50% and ≥10% lower than baseline), progression of mild-moderate/moderate AFMR to severe, and persistent regression of AFMR to no/trivial...
March 17, 2024: Journal of the American College of Cardiology
https://read.qxmd.com/read/38530307/photoplethysmography-based-atrial-fibrillation-detection-a-continually-growing-field
#6
JOURNAL ARTICLE
Cheng Ding, Ran Xiao, Weijia Wang, Elizabeth Holdsworth, Xiao Hu
Atrial fibrillation (AF) is a prevalent cardiac arrhythmia associated with significant health ramifications, including an elevated susceptibility to ischemic stroke, heart disease, and heightened mortality. Photoplethysmography (PPG) has emerged as a promising technology for continuous AF monitoring for its cost-effectiveness and widespread integration into wearable devices. Our team previously conducted an exhaustive review on PPG-based AF detection before June 2019. However, since then, more advanced technologies have emerged in this field...
March 26, 2024: Physiological Measurement
https://read.qxmd.com/read/38529655/repeated-measurement-of-the-novel-atrial-biomarker-bmp10-bone-morphogenetic-protein-10-refines-risk-stratification-in-anticoagulated-patients-with-atrial-fibrillation-insights-from-the-aristotle-trial
#7
JOURNAL ARTICLE
Konstantinos I Gkarmiris, Johan Lindbäck, John H Alexander, Christopher B Granger, Peter Kastner, Renato D Lopes, André Ziegler, Jonas Oldgren, Agneta Siegbahn, Lars Wallentin, Ziad Hijazi
BACKGROUND: BMP10 (bone morphogenic protein 10) has emerged as a novel biomarker associated with the risk of ischemic stroke and other outcomes in patients with atrial fibrillation (AF). The study aimed to determine if repeated BMP10 measurements improve prognostication of cardiovascular events in patients with AF. METHODS AND RESULTS: BMP10 was measured using a prototype Elecsys immunoassay in plasma samples collected at randomization and after 2 months in patients with AF randomized to apixaban or warfarin in the ARISTOTLE (Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation) trial (n=2878)...
March 26, 2024: Journal of the American Heart Association
https://read.qxmd.com/read/38528758/clinical-midterm-results-of-surgical-aortic-valve-replacement-with-sutureless-valves
#8
JOURNAL ARTICLE
Soonchang Hong, Jung-Woo Son, Yungjin Yoon
BACKGROUND: Sutureless aortic valves may enable shorter procedure times, which benefits patients with elevated surgical risk. We describe the outcomes of patients with aortic stenosis who underwent aortic valve replacement (AVR) using the sutureless Perceval aortic bioprosthesis. METHODS: Data from a retrospective cohort were obtained from a clinical database. The study enrolled patients with symptomatic severe aortic stenosis who underwent surgical AVR with a sutureless bioprosthesis between August 2015 and December 2020...
March 26, 2024: Journal of chest surgery
https://read.qxmd.com/read/38525596/estimating-vitamin-k-antagonist-anticoagulation-benefit-in-people-with-atrial-fibrillation-accounting-for-competing-risks-evidence-from-12-randomized-trials
#9
JOURNAL ARTICLE
Sachin J Shah, Carl van Walraven, Sun Young Jeon, John Boscardin, F D Richard Hobbs, Stuart J Connolly, Michael D Ezekowitz, Kenneth E Covinsky, Margaret C Fang, Daniel E Singer
BACKGROUND: Patients with atrial fibrillation have a high mortality rate that is only partially attributable to vascular outcomes. The competing risk of death may affect the expected anticoagulant benefit. We determined if competing risks materially affect the guideline-endorsed estimate of anticoagulant benefit. METHODS: We conducted a secondary analysis of 12 randomized controlled trials that randomized patients with atrial fibrillation to vitamin K antagonists (VKAs) or either placebo or antiplatelets...
March 25, 2024: Circulation. Cardiovascular Quality and Outcomes
https://read.qxmd.com/read/38525097/contemporary-spectrum-characteristics-and-outcomes-of-adult-patients-with-rheumatic-valvular-disease-in-china-insights-from-the-china-vhd-study
#10
JOURNAL ARTICLE
Zhenya Duan, Yunqing Ye, Zhe Li, Bin Zhang, Qingrong Liu, Zhenyan Zhao, Weiwei Wang, Zikai Yu, Haitong Zhang, Qinghao Zhao, Bincheng Wang, Junxing Lv, Shuai Guo, Haocheng Ren, Runlin Gao, Haiyan Xu, Yongjian Wu
BACKGROUND: Rheumatic valvular disease (RVD) represents a significant health concern in developing countries, yet a scarcity of detailed data exists. This study conducts a comprehensive examination of RVD patients in China, exploring aspects of the disease's spectrum, characteristics, investigation, management, and outcomes. METHODS: The China Valvular Heart Disease (China-VHD) study, a nationwide, multicenter, prospective observational study, enrolled 13,917 adults with moderate-to-severe valvular heart disease from April to June 2018...
June 2024: Int J Cardiol Cardiovasc Risk Prev
https://read.qxmd.com/read/38522770/prevalence-and-impact-of-pulmonary-hypertension-on-acute-decompensated-heart-failure-with-preserved-ejection-fraction-hospitalizations-a-five-year-retrospective-analysis
#11
REVIEW
Omar Al Wahadneh, Qusai Alitter, Apoorva Raju, Nmair Alziadin, Abdullah H Alshurafa, Hamdi Osama Aldabbas, Ibrahim Shaik
Heart Failure with Preserved Ejection Fraction (HFpEF) is a major and common cardiovascular condition with widely variable clinical outcomes. Pulmonary hypertension (PH) often co-exists with HFpEF and tends to affect patient outcomes; this study aims to identify the impact of PH on the clinical outcome of patients admitted to the hospital with acute HFpEF exacerbations. We analyzed data from the National Inpatient Sample between 2016 and 2020, focusing on 464,438 acute HFpEF exacerbation hospitalizations. Outcomes were compared between those with PH (27...
March 22, 2024: Current Problems in Cardiology
https://read.qxmd.com/read/38521289/predictors-of-mortality-and-burden-of-arrhythmias-in-endstage-heart-failure
#12
REVIEW
Endurance Evbayekha, Akanimo Antia, Brittany Dixon, Craig K Reiss, Shane Larue
BACKGROUND: Heart failure (HF) is a significant cause of morbidity and mortality in the United States, contributing to approximately 1 in 8 deaths. Individuals with end-stage HF (eHF) experience debilitating symptoms leading to poor quality of life (QoL). METHODS: We used the ICD-10 code for eHF (I5084) from the National Inpatient Sample (NIS) (2016-2020) to identify all patients with eHF. We used a multivariable logistic regression model to adjust for confounders and estimate the mortality probability in each arrhythmia cohort...
March 21, 2024: Current Problems in Cardiology
https://read.qxmd.com/read/38517643/impact-of-healthcare-associated-infections-within-7-days-of-acute-stroke-on-health-outcomes-and-risk-of-care-dependency-a-multi-centre-registry-based-cohort-study
#13
JOURNAL ARTICLE
David Fluck, Christopher H Fry, Jonathan Robin, Brendan Affley, Puneet Kakar, Pankaj Sharma, Thang S Han
Healthcare-associated infections (HCAIs) in patients admitted with acute conditions remain a major challenge to healthcare services. Here, we assessed the impact of HCAIs acquired within 7-days of acute stroke on indicators of care-quality outcomes and dependency. Data were prospectively collected (2014-2016) from the Sentinel Stroke National Audit Programme for 3309 patients (mean age = 76.2 yr, SD = 13.5) admitted to four UK hyperacute stroke units (HASU). Associations between variables were assessed by multivariable logistic regression (odds ratios, 95% confidence intervals), adjusted for age, sex, co-morbidities, pre-stroke disability, swallow screening, stroke type and severity...
March 22, 2024: Internal and Emergency Medicine
https://read.qxmd.com/read/38516784/incremental-value-of-a-metabolic-risk-score-for-heart-failure-mortality-a-population-based-study
#14
JOURNAL ARTICLE
Jungnam Joo, Joseph J Shearer, Anna Wolska, Alan T Remaley, James D Otvos, Margery A Connelly, Maureen Sampson, Suzette J Bielinski, Nicholas B Larson, Hoyoung Park, Katherine M Conners, Sarah Turecamo, Véronique L Roger
BACKGROUND: Heart failure is heterogeneous syndrome with persistently high mortality. Nuclear magnetic resonance spectroscopy enables high-throughput metabolomics, suitable for precision phenotyping. We aimed to use targeted metabolomics to derive a metabolic risk score (MRS) that improved mortality risk stratification in heart failure. METHODS: Nuclear magnetic resonance was used to measure 21 metabolites (lipoprotein subspecies, branched-chain amino acids, alanine, GlycA, ketone bodies, glucose, and citrate) in plasma collected from a heart failure community cohort...
March 22, 2024: Circulation. Genomic and Precision Medicine
https://read.qxmd.com/read/38515077/usefulness-of-lactate-to-albumin-ratio-for-predicting-in-hospital-mortality-in-atrial-fibrillation-patients-admitted-to-the-intensive-care-unit-a-retrospective-analysis-from-mimic-iv-database
#15
JOURNAL ARTICLE
Ting Huang, Sen Lin
BACKGROUND: High lactate to albumin ratio (LAR) has been reported to be associated to with poor prognosis in patients admitted to the intensive care unit (ICU). However, its role in predicting in-hospital mortality in AF patients admitted to ICU has not been explored. METHODS: The Medical Information Mart for Intensive Care-IV (MIMIC-IV) database was used to retrieve information on patients who had been diagnosed with AF. X-tile software was utilized to determine the optimal cut-off LAR...
March 21, 2024: BMC Anesthesiology
https://read.qxmd.com/read/38515030/association-of-red-cell-distribution-width-albumin-ratio-and-in-hospital-mortality-in-patients-with-atrial-fibrillation-base-on-medical-information-mart-for-intensive-care-iv-database
#16
JOURNAL ARTICLE
Li-Ya Pan, Jing Song
BACKGROUND: Atrial fibrillation (AF) is a common cardiac arrhythmia. The ratio of red cell distribution width (RDW) to albumin has been recognized as a reliable prognostic marker for poor outcomes in a variety of diseases. However, the evidence regarding the association between RDW to albumin ratio (RAR) and in hospital mortality in patients with AF admitted to the Intensive Care Unit (ICU) currently was unclear. The purpose of this study was to explore the association between RAR and in hospital mortality in patients with AF in the ICU...
March 21, 2024: BMC Cardiovascular Disorders
https://read.qxmd.com/read/38514992/impact-of-heart-rate-changes-during-hospitalization-on-outcome-in-heart-failure-with-preserved-ejection-fraction
#17
JOURNAL ARTICLE
Dan Liu, Xiaotong Cui, Yamei Xu, Lei Xu, Zhonglei Xie, Shuai Yuan, Peng Wang, Yanyan Wang, Sanli Qian, Hui Gong, Peter Nordbeck, Jiefu Yang, Jingmin Zhou, Junbo Ge, Aijun Sun
AIMS: The benefits of lowering heart rate (HR) in heart failure (HF) with preserved ejection fraction (HFpEF) patients are still a matter of debate. This study aimed to investigate the relationship between changes in HR during hospitalization and cardiovascular (CV) events and all-cause death in hospitalized HFpEF patients. METHODS AND RESULTS: Hospitalized HF patients between January 2017 and December 2021 were consecutively enrolled in a national, multicentred, and prospective registry database, the China Cardiovascular Association Database-HF Center Registry...
March 21, 2024: ESC Heart Failure
https://read.qxmd.com/read/38511316/effectiveness-and-safety-of-edoxaban-compared-with-apixaban-in-elderly-patients-with-nonvalvular-atrial-fibrillation-a-real-world-population-based-cohort-study
#18
JOURNAL ARTICLE
Richard Chiv, Sarah Beradid, Samy Suissa, Christel Renoux
BACKGROUND: The very elderly (≥80 years) are at high risk of nonvalvular atrial fibrillation and thromboembolism. Given its recent approval, the comparative effectiveness and safety of edoxaban in this population, relative to the commonly used apixaban, remain unknown. METHODS: Using the United Kingdom Clinical Practice Research Datalink, we identified a cohort of patients aged ≥80 with incident nonvalvular atrial fibrillation and newly treated with edoxaban or apixaban between 2015 and 2021...
March 21, 2024: Stroke; a Journal of Cerebral Circulation
https://read.qxmd.com/read/38510554/a-review-of-the-impact-pathophysiology-and-management-of-atrial-fibrillation-in-patients-with-heart-failure-with-preserved-ejection-fraction
#19
REVIEW
Cicely Dye, Mark Dela Cruz, Timothy Larsen, Gatha Nair, Karolina Marinescu, Tisha Suboc, Erica Engelstein, Jennifer Marsidi, Priya Patel, Parikshit Sharma, Annabelle Santos Volgman
Patients with heart failure with preserved ejection fraction (HFpEF) and atrial fibrillation (AF) have increased mortality and increased risk of stroke. Due to the heterogeneous nature of both disease processes, it is difficult to ascertain whether the diagnosis and progression of AF is the cause of deterioration or if it is a symptom of worsening heart failure. This presents physicians with a clinical conundrum of whether optimizing their heart failure will decrease the overall AF burden or if restoration of sinus rhythm is necessary to optimize patients with HFpEF...
September 2023: American heart journal plus: cardiology research and practice
https://read.qxmd.com/read/38510506/the-changing-landscape-of-cardiac-co-morbidities-and-in-hospital-cardiac-complications-mediating-covid-19-mortality-between-2020-and-2021
#20
JOURNAL ARTICLE
Thomas R Basala, Marissa E Dulas, Alexis Albers, Sara D Olson, Brynn Okeson, Jay H Traverse
BACKGROUND: Cardiac co-morbidities and in-hospital cardiac complications significantly contribute to COVID-19 mortality. However, their influence on mortality between 2021 and 2020 may differ due to the availability of vaccines, different viral strains, and therapeutic advancements. METHODS: We performed a retrospective chart review and individual patient analysis of all COVID-19 associated in-patient deaths in 2020 ( n  = 346) and 2021( n  = 527) in a large Minneapolis health system...
January 2024: American heart journal plus: cardiology research and practice
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