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JOURNAL ARTICLE
Valery L Feigin, Theo Vos, Fares Alahdab, Arianna Maever L Amit, Till Winfried Bärnighausen, Ettore Beghi, Mahya Beheshti, Prachi P Chavan, Michael H Criqui, Rupak Desai, Samath Dhamminda Dharmaratne, E Ray Dorsey, Arielle Wilder Eagan, Islam Y Elgendy, Irina Filip, Simona Giampaoli, Giorgia Giussani, Nima Hafezi-Nejad, Michael K Hole, Takayoshi Ikeda, Catherine Owens Johnson, Rizwan Kalani, Khaled Khatab, Jagdish Khubchandani, Daniel Kim, Walter J Koroshetz, Vijay Krishnamoorthy, Rita V Krishnamurthi, Xuefeng Liu, Warren David Lo, Giancarlo Logroscino, George A Mensah, Ted R Miller, Salahuddin Mohammed, Ali H Mokdad, Maziar Moradi-Lakeh, Shane Douglas Morrison, Veeresh Kumar N Shivamurthy, Mohsen Naghavi, Emma Nichols, Bo Norrving, Christopher M Odell, Elisabetta Pupillo, Amir Radfar, Gregory A Roth, Azadeh Shafieesabet, Aziz Sheikh, Sara Sheikhbahaei, Jae Il Shin, Jasvinder A Singh, Timothy J Steiner, Lars Jacob Stovner, Mitchell Taylor Wallin, Jordan Weiss, Chenkai Wu, Joseph Raymond Zunt, Jaimie D Adelson, Christopher J L Murray
IMPORTANCE: Accurate and up-to-date estimates on incidence, prevalence, mortality, and disability-adjusted life-years (burden) of neurological disorders are the backbone of evidence-based health care planning and resource allocation for these disorders. It appears that no such estimates have been reported at the state level for the US. OBJECTIVE: To present burden estimates of major neurological disorders in the US states by age and sex from 1990 to 2017. DESIGN, SETTING, AND PARTICIPANTS: This is a systematic analysis of the Global Burden of Disease (GBD) 2017 study...
February 1, 2021: JAMA Neurology
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JOURNAL ARTICLE
Paula Tejera, Raja-Elie E Abdulnour, Zhaozhong Zhu, Li Su, Bruce D Levy, David C Christiani
OBJECTIVES: Acute respiratory distress syndrome is characterized by an overly exuberant inflammatory state in the lung. Specialized proresolving mediators are endogenous agonists for the resolution of lung inflammation and injury in health, yet their association with acute respiratory distress syndrome severity and outcomes remains to be defined. In the current study, we investigate associations between plasma levels of specialized proresolving mediators and acute respiratory distress syndrome severity and mortality...
October 2020: Critical care explorations
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JOURNAL ARTICLE
Markos Kalligeros, Karen T Tashima, Evangelia K Mylona, Natasha Rybak, Timothy P Flanigan, Dimitrios Farmakiotis, Curt G Beckwith, Martha Sanchez, Marguerite Neill, Jennie E Johnson, Joseph M Garland, Su Aung, Katrina M Byrd, Thomas O'Brien, Aakriti Pandita, Jad Aridi, Raul Macias Gil, Jerome Larkin, Fadi Shehadeh, Eleftherios Mylonakis
Background: The US Food and Drug Administration issued an Emergency Use Authorization for remdesivir use in patients with severe COVID-19. Methods: We utilized data from 2 quaternary acute care hospitals. The outcomes of interest were the impact of remdesivir on in-hospital death by day 28 and time to recovery, clinical improvement, and discharge. We utilized Cox proportional hazards models and stratified log-rank tests. Results: Two hundred twenty-four patients were included in the study...
October 2020: Open Forum Infectious Diseases
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JOURNAL ARTICLE
Shakeel M Jamal, Asim Kichloo, Michael Albosta, Beth Bailey, Jagmeet Singh, Farah Wani, Muhammad Shah Zaib, Muhammad Ahmad, Muhammad Dilawar Khan, Ronak Soni, Michael Aljadah, Hafiz Waqas Khan, Mahin Khan, Muhammad Z Khan
Infective endocarditis (IE) complicated by heart block can have adverse outcomes and usually requires immediate surgical and cardiac interventions. Data on outcomes and trends in patients with IE with concurrent heart block are lacking. Patients with a primary diagnosis of IE with or without heart block were identified by querying the Healthcare Cost and Utilization Project database, specifically the National Inpatient Sample for the years 2013 and 2014, based on International Classification of Diseases Clinical Modification Ninth Revision codes...
February 2021: Journal of Investigative Medicine: the Official Publication of the American Federation for Clinical Research
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JOURNAL ARTICLE
Jia-Wei Shen, Pei-Xun Zhang, You-Zhong An, Bao-Guo Jiang
OBJECTIVE: To report outcomes of geriatric patients undergoing hip fracture surgery or arthroplasty with or without preoperative pneumonia and to evaluate the influence of pneumonia severity on patient prognosis. METHODS: In this single center retrospective study, we included geriatric patients (≥60 years old) who had undergone hip fracture surgery or arthroplasty at Peking University People's Hospital from January 2008 to September 2018. Patients with fractures caused by neoplasms or patients with incomplete clinical data were excluded...
October 28, 2020: Orthopaedic Surgery
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JOURNAL ARTICLE
Rebbecca Lilley, Brett Maclennan, Gabrielle Davie, Bronwen M McNoe, Simon Horsburgh, Tim R Driscoll
INTRODUCTION: Analyses of secular trends in work-related fatal injury in New Zealand have previously only considered the total working population, potentially hiding trends for important subgroups of workers. This paper examines trends in work-related fatalities in worker subgroups between 2005 and 2014 to indicate where workplace safety action should be prioritised. METHODS: A dataset of fatally injured workers was created; all persons aged 15-84 years, fatally injured in the period 2005-2014, were identified from mortality records, linked to coronial records which were then reviewed for work relatedness...
October 26, 2020: Occupational and Environmental Medicine
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JOURNAL ARTICLE
Colin Laverty, Homer Tien, Andrew Beckett, Avery Nathens, J P Rivest-Caissy, Luis Teodoro da Luz
OBJECTIVES: Military Forward Aeromedical Evacuation and civilian Helicopter Emergency Medical Services are widely used to conduct Primary Aeromedical Retrieval. Crew composition in Primary Aeromedical Retrieval missions varies considerably. The ideal composition is unknown. Thus, we conducted a descriptive systematic review on mortality and other outcomes for different Primary Aeromedical Retrieval crew compositions. METHODS: Medline, Embase, and Cochrane Controlled Trials Register were searched up to January 2020...
September 2020: CJEM
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JOURNAL ARTICLE
Jingbo Chen, Gen Li, Mingsheng Chen, Gui Jin, Shuanglin Zhao, Zelin Bai, Jun Yang, Huayou Liang, Jia Xu, Jian Sun, Mingxin Qin
Cerebral edema (CE) is a non-specific pathological swelling of the brain secondary to any type of neurological injury. The real-time monitoring of focal CE mostly found in early stage is of great significance to reduce mortality and disability. Magnetic Induction Phase Shift (MIPS) is expected to achieve non-invasive continuous monitoring of CE. However, most existing MIPS sensors are made of hard materials which makes it difficult to accurately retrieve CE information. In this article, we designed a conformal two-coil structure and a single-coil structure, and studied their sensitivity map using finite element method (FEM)...
2020: PeerJ
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JOURNAL ARTICLE
Vijay S Are, Shannon M Knapp, Ambar Banerjee, Hani Shamseddeen, Marwan Ghabril, Eric Orman, Kavish R Patidar, Naga Chalasani, Archita P Desai
INTRODUCTION: With increasing burden of obesity and liver disease in the United States, a better understanding of bariatric surgery in context of cirrhosis is needed. We described trends of hospital-based outcomes of bariatric surgery among cirrhotics and determined effect of volume status and type of surgery on these outcomes. METHODS: In this population-based study, admissions for bariatric surgery were extracted from the National Inpatient Sample using International Classification of Diseases, 9th and 10th Revision, Clinical Modification codes from 2004 to 2016 and grouped by cirrhosis status, type of bariatric surgery, and center volume...
October 19, 2020: American Journal of Gastroenterology
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JOURNAL ARTICLE
Amy Heinzerling, Rebecca L Laws, Matt Frederick, Rebecca Jackson, Gayle Windham, Barbara Materna, Robert Harrison
BACKGROUND: As climate change increases global temperatures, heat-related morbidity and mortality are projected to rise. Outdoor workers and those who perform exertional tasks are particularly susceptible to heat-related illness (HRI). Using workers' compensation data, we aimed to describe rates of occupational HRI in California and identify demographic and occupational risk factors to inform prevention efforts. METHODS: We identified HRI cases during 2000-2017 in the California Workers' Compensation Information System (WCIS) using International Classification of Diseases Ninth and Tenth Revision codes, WCIS nature and cause of injury codes, and HRI keywords...
December 2020: American Journal of Industrial Medicine
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JOURNAL ARTICLE
(no author information available yet)
BACKGROUND: Rigorous analysis of levels and trends in exposure to leading risk factors and quantification of their effect on human health are important to identify where public health is making progress and in which cases current efforts are inadequate. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 provides a standardised and comprehensive assessment of the magnitude of risk factor exposure, relative risk, and attributable burden of disease. METHODS: GBD 2019 estimated attributable mortality, years of life lost (YLLs), years of life lived with disability (YLDs), and disability-adjusted life-years (DALYs) for 87 risk factors and combinations of risk factors, at the global level, regionally, and for 204 countries and territories...
October 17, 2020: Lancet
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JOURNAL ARTICLE
(no author information available yet)
BACKGROUND: In an era of shifting global agendas and expanded emphasis on non-communicable diseases and injuries along with communicable diseases, sound evidence on trends by cause at the national level is essential. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) provides a systematic scientific assessment of published, publicly available, and contributed data on incidence, prevalence, and mortality for a mutually exclusive and collectively exhaustive list of diseases and injuries...
October 17, 2020: Lancet
#13
JOURNAL ARTICLE
Ahmed Arshad, Ann M Polcari, Neethi P Pinto, Mark B Slidell
PURPOSE OF REVIEW: Traumatic injuries are a leading cause of pediatric mortality; pediatric ICUs (PICUs) are an important but potentially limited resource associated with high costs. In an era of rising healthcare costs, appropriate resource utilization is important. Here, we examine evidence-based guidelines supporting the management of pediatric traumatic injury outside of the PICU. RECENT FINDINGS: Historical management of solid organ injury and traumatic brain injury was focused on operative management...
December 2020: Current Opinion in Pediatrics
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JOURNAL ARTICLE
Merianne Rose Spencer, Sally C Curtin, Holly Hedegaard
Excessive alcohol consumption is a well-known risk factor for mortality and has been causally linked to many diseases, conditions and injuries, including alcohol-attributable cancer, liver cirrhosis, and alcohol poisonings (1). Alcohol-induced deaths, or deaths from dependent and nondependent use of alcohol, as well as accidental poisoning by alcohol (2), have been increasing in the United States since 1999 with differences by sex, age, urban-rural classification, and other demographic characteristics (3,4)...
October 2020: NCHS Data Brief
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JOURNAL ARTICLE
Ayşe Gülşen Teker, Ahmet Naci Emecen, Gül Ergör
BACKGROUND: Making the right decisions in the field of public health depends on the reliable recording of statistical data such as death and birth. There have been radical changes and innovations in the death registration since 2009 in Turkey to improve reporting. AIMS: To examine the distribution and the trend of causes of death between the years 2009 and 2017 in Turkey. STUDY DESIGN: Descriptive study. METHODS: In this study, the causes of death were evaluated in three groups used in the Global Burden of Disease study...
March 2021: Balkan Medical Journal
#16
JOURNAL ARTICLE
Chiaki Toida, Takashi Muguruma, Masayasu Gakumazawa, Mafumi Shinohara, Takeru Abe, Ichiro Takeuchi, Naoto Morimura
Injury is a major cause of worldwide child mortality. This retrospective nationwide study aimed to evaluate the characteristics of paediatric injured patients in Japan and their in-hospital mortality trends from 2009 to 2018. Injured patients aged <17 years were enrolled. Data were extracted from the Japan Trauma Data Bank. In the Cochran-Armitage test, in-hospital mortality significantly decreased during the study period ( p < 0.001), except among patients <1 year old, and yearly reductions were observed among those with an Injury Severity Score ≥16 and survival rate ≥50% ( p < 0...
October 12, 2020: Journal of Clinical Medicine
#17
JOURNAL ARTICLE
Hannah Lewis, Breda O'Neill, Naomi Edmonds
No abstract text is available yet for this article.
December 2020: Paediatric Anaesthesia
#18
JOURNAL ARTICLE
Lichen Ouyang, Yeli Gong, Yan Zhu, Jie Gong
BACKGROUND: we aimed to explore the relationship of acute kidney injury (AKI) with the severity and mortality of coronavirus disease 2019 (COVID-19). METHODS: A systematic literature search was conducted in PubMed, EMBASE, Scopus, Web of Science, MedRxiv Database. We compared the laboratory indicators of renal impairment and incidences of AKI in the severe versus non-severe cases, and survival versus non-survival cases, respectively. RESULTS: In 41 studies with 10,335 COVID-19 patients, the serum creatinine (sCr) in severe cases was much higher than that in non-severe cases (SMD = 0...
May 2021: American Journal of Emergency Medicine
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JOURNAL ARTICLE
Ram Alluri, Gabriel Bouz, Samantha Solaru, Hyunwoo Kang, Jeffrey Wang, Raymond J Hah
STUDY DESIGN: Retrospective database analysis. OBJECTIVE: To identify nationwide temporal trends in management of geriatric odontoid fractures and to compare comorbidities, inpatient complications, hospital characteristics, and cost between patients receiving operative versus nonoperative management. SUMMARY OF BACKGROUND DATA: The treatment of geriatric odontoid fractures remains controversial with some studies demonstrating decreased mortality and improved functional outcomes associated with operative management and significant morbidity associated with halo devices during nonoperative management...
January 15, 2021: Spine
#20
Jurij Janež, Urban Stupan, Gregor Norčič
INTRODUCTION: Adult perineal impalement injuries are uncommon and notorious for their complex injury pattern and risk of massive pelvic bleeding. They present a challenge for the treating physician as there is no consensus about the optimal treatment in the existing literature. In most cases patients need operative intervention. CASE PRESENTATION: In this article the authors present a case report of a 63-year old man with an impalement injury in the left gluteus, who was managed conservatively...
2020: International Journal of Surgery Case Reports
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