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José Francisco Melo Júnior, Nathalie Jeanne Bravo-Valenzuela, Luciano Marcondes Machado Nardozza, Alberto Borges Peixoto, Rosiane Mattar, Wellington P Martins, Gabriele Tonni, Edward Araujo Júnior
Objectives To determine the reference range for the myocardial area in healthy fetuses using three-dimensional (3D) ultrasonography and validate these results in fetuses of pregnant women with pre-gestational diabetes mellitus (DM). Methods This cross-sectional retrospective study included 168 healthy pregnant women between gestational weeks 20 and 33+6 days. The myocardial area was measured using spatio-temporal image correlation (STIC) in the four-chamber view. Polynomial regression models were used, and the goodness of fit of the models were evaluated by the coefficient of determination (R2)...
February 14, 2019: Journal of Perinatal Medicine
Yessica Parera-Valadez, Alejandro Yam-Puc, Lluvia Korynthia López-Aguiar, Rocío Borges-Argáez, Mario Alberto Figueroa-Saldivar, Mirbella Cáceres-Farfán, Norma Angélica Márquez-Velázquez, Alejandra Prieto-Davó
The quest for novel natural products has recently focused on the marine environment as a source for novel microorganisms. Although isolation of marine-derived actinomycete strains is now common, understanding their distribution in the oceans and their adaptation to this environment can be helpful in the selection of isolates for further novel secondary metabolite discovery. This study explores the taxonomic diversity of marine-derived actinomycetes from distinct environments in the coastal areas of the Yucatan Peninsula and their adaptation to the marine environment as a first step towards novel natural product discovery...
February 14, 2019: Microbial Ecology
Anna Tölli, Charlotte Höybye, Bo-Michael Bellander, Jörgen Borg
OBJECTIVE: To explore associations between pituitary dysfunction and clinical outcome at 12 months after traumatic brain injury and aneurysmal subarachnoid haemorrhage. METHODS: Prospective cohort study of 82 patients with traumatic brain injury and 45 with aneurysmal subarachnoid haemorrhage, included at 1 neurointensive care unit. Baseline data comprised age, sex, Glasgow Coma Scale (GCS) score, S100B and pupil light reactions. Hormone data were collected in the neurointensive care unit and 3, 6 and 12 months...
February 14, 2019: Journal of Rehabilitation Medicine
Michael O Rivett, Laura Budimir, Nicholas Mannix, Alexandra V M Miller, Marc J Addison, Phideria Moyo, Gift J Wanangwa, Owen L Phiri, Chrispine E Songola, Muthi Nhlema, Mavuto A S Thomas, Reid T Polmanteer, Amando Borge, Robert M Kalin
Effective response to groundwater salinity in the developing world may critically safeguard drinking-water supplies. Groundwater resources throughout rural Africa are exploited by a vast and increasing number of hand-pumped boreholes for community supply. Our research in TA Ngabu (Shire Valley), Southern Malawi aims to: define groundwater-salinity problem occurrence within the semi-arid alluvial-valley aquifer, rural developing-world setting; critique current capacity to respond; and, to discuss future response options - in particular considering the need to explore alternative options that boldly go beyond the world of hand-pumped groundwater supply...
February 25, 2019: Science of the Total Environment
Paula Dresch Portella, Bruna Leticia Vessoni Menoncin, Juliana Feltrin De Souza, José Vitor Nogara Borges De Menezes, Fabian Calixto Fraiz, Luciana Reichert Da Silva Assunção
BACKGROUND: Molar-incisor hypomineralization (MIH) is associated with unfavorable dental conditions such as dental caries and may consequently impact Oral Health-Related Quality of Life (OHRQoL). OBJECTIVE: To assess the impact of MIH on OHRQoL in children with early mixed dentition. METHOD: A population-based cross-sectional study of 728 8-year-old children from the public school system in Curitiba, Brazil, was conducted. The Child Perception Questionnaire for 8 to 10-year-olds (CPQ8-10 ) was used to evaluate OHRQoL...
February 13, 2019: International Journal of Paediatric Dentistry
Albina Moreira, Miguel Borges Silva, Ana Afonso, Cristina Rodrigues
We report a clinical case of adult-onset Still's disease. In addition to the imaging features of the case, the following aspects are also briefly described: clinical presentation (prolonged fever associated with migratory polyarthritis and skin rash), treatment performed (resort to anti-inflammatory and corticoid), and clinical evolution of the patient after having performed the adult-onset. The treatment was found to be appropriate as the patient presented a favourable clinical evolution. LEARNING POINTS: Skin manifestations are associated with systemic diseases...
2019: European Journal of Case Reports in Internal Medicine
Børge Holden, Laura Görtz-Nagtzaam
No abstract text is available yet for this article.
February 12, 2019: Tidsskrift for Den Norske Lægeforening: Tidsskrift for Praktisk Medicin, Ny Række
João Marcelo Ceron, Klaus Steding-Jessen, Cristine Hoepers, Lisandro Zambenedetti Granville, Cíntia Borges Margi
IoT botnets have been used to launch Distributed Denial-of-Service (DDoS) attacks affecting the Internet infrastructure. To protect the Internet from such threats and improve security mechanisms, it is critical to understand the botnets' intents and characterize their behavior. Current malware analysis solutions, when faced with IoT, present limitations in regard to the network access containment and network traffic manipulation. In this paper, we present an approach for handling the network traffic generated by the IoT malware in an analysis environment...
February 11, 2019: Sensors
Marco S Rodrigues, Joel Borges, Manuela Proença, Paulo Pedrosa, Nicolas Martin, Konstantin Romanyuk, Andrei L Kholkin, Filipe Vaz
In this work, a versatile method is proposed to increase the sensitivity of optical sensors based on the localized surface plasmon resonance (LSPR) phenomenon. It combines a physical deposition method with the Oblique Angle Deposition (OAD) technique, allowing the preparation of plasmonic thin films with tailored porosity. Thin films of Au-TiO<sub>2</sub> were deposited by reactive magnetron sputtering in a 3D nanostructure (zigzag growth), at different incidence angles (0º ≤ α ≤ 80º), followed by in-air thermal annealing at 400 ºC to induce the growth of the Au nanoparticles...
February 12, 2019: Nanotechnology
Corina Benjet, Raúl A Gutiérrez-García, Adrián Abrego-Ramírez, Guilherme Borges, Anabell Covarrubias-Díaz, Ma Del Socorro Durán, Rogaciano González-González, Alicia E Hermosillo-de la Torre, Kalina I Martínez-Martínez, María Elena Medina-Mora, Humberto Mejía-Zarazúa, Gustavo Pérez-Tarango, María Alicia Zavala-Berbena, Philippe Mortier
OBJECTIVE: To estimate psychopathology and self-harm behavior of incoming first-year college students, sociodemographic correlates, service use and willingness to seek treatment. MATERIALS AND METHODS: 4 189 male and female incoming first-year students of six universities in four different states of Mexico responded to an online survey with a 79.3% response rate. RESULTS: Almost one in three incoming students has experienced some type of psychopathology; however, only one in five has received treatment...
2019: Salud Pública de México
Guilherme Borges, Ricardo Orozco, Jorge Villatoro, Maria Elena Medina-Mora, Clara Fleiz, Jessica Díaz-Salazar
OBJECTIVE: To provide updated information regarding the 12-month prevalence and associated sociodemographic factors for suicide ideation and behavior (plan and attempts) to substantiate preventive programs in Mexico. MATERIALS AND METHODS: Cross-sectional nationally representative survey, conducted during 2016 (n=56 877) among those 12-65 years old living in rural, urban and metropolitan dwellings. RESULTS: The prevalence of suicide ideation in the last 12-months was 2...
2019: Salud Pública de México
Sabina Beheshti, Christian M Madsen, Anette Varbo, Børge G Nordestgaard
Context: How best to identify families with premature myocardial infarction is unclear. Objective: We compared approaches to identify familial premature myocardial infarction in the general population using different familial hypercholesterolemia(FH) criteria and low-density lipoprotein(LDL) cholesterol cut points. Design and Setting: Clinical and mutation criteria for FH, and LDL cholesterol cut points were applied for identification of familial premature myocardial infarction in 106,732 individuals from the Copenhagen General Population Study...
February 7, 2019: Journal of Clinical Endocrinology and Metabolism
Fernanda das Neves Costa, Ricardo Moreira Borges, Gilda Guimarães Leitão, Gerold Jerz
Salicornia species have just been introduced to the European market as a vegetable named 'samphire', 'green asparagus' or 'sea asparagus'. Due to its increasing attention, and associated value, minor compounds of Salicornia gaudichaudiana Moq were investigated. The use of countercurrent chromatography and mass spectrometry enabled the search for known, as well as potentially novel natural products. Their identification was achieved based on molecular weights, and mass-spectrometric fragmentation data. Low detection limits enabled the visualization of all compounds with their identification in almost real time close to the preparative countercurrent chromatography experiment...
February 11, 2019: Journal of Separation Science
Christian M Madsen, Anette Varbo, Børge G Nordestgaard
BACKGROUND: HDL is quantitatively the most important lipoprotein in most species and mechanistic evidence points toward a role for HDL in normal immune function. We tested the hypothesis that concentrations of HDL cholesterol are associated with risk of autoimmune disease. METHODS: From 2 studies of the general population- the Copenhagen General Population Study and the Co-penhagen City Heart study-we included 107954 and 9387 individuals with baseline measurements of HDL cholesterol...
February 11, 2019: Clinical Chemistry
Bianca Ferrarini Zanetti, Daniela Paes de Almeida Ferreira Braga, Amanda Souza Setti, Assumpto Iaconelli, Edson Borges
The aim of this study was to investigate which factors contribute to the incidence of biochemical pregnancy (BP) in intracytoplasmic sperm injection (ICSI) cycles. This cohort study included cycles performed from June 2010 to September 2016 in a private, university-affiliated IVF centre. Cycles were split into four groups, depending on the pregnancy outcomes: Clinical Pregnancy (CP, n = 903), Biochemical Pregnancy (BP, n = 55), Miscarriage (MI, n = 142) and Negative Pregnancy (NP, n = 2034)...
February 8, 2019: Reproductive Biology
Ana Verdelho, Sofia Madureira, Manuel Correia, José Manuel Ferro, Mário Rodrigues, Manuel Gonçalves-Pereira, Mafalda Gonçalves, Ana Catarina Santos, Pedro Vilela, Helena Bárrios, Mariana Borges, Helena Santa-Clara
BACKGROUND: Cognitive impairment and cerebrovascular pathology are both frequent with ageing. Cognitive impairment due to vascular pathology of the brain, termed vascular cognitive impairment (VCI), is one of the most frequent causes of cognitive impairment in elderly subjects. Thus far, VCI has no specific pharmacological treatment. Recent observational studies have suggested a protective effect of physical activity in cognition, but adequate randomised controlled trials (RCT) are lacking...
February 11, 2019: Trials
Edson Borges, Bianca Ferrarini Zanetti, Daniela Paes de Almeida Ferreira Braga, Amanda Souza Setti, Rita Cássia Sávio Figueira, Assumpto Iaconelli
OBJECTIVE: To study which factors affect perinatal outcomes in intracytoplasmic sperm injection (ICSI) cycles. METHODS: Data was obtained from 402 live births born to 307 patients undergoing ICSI cycles in a private university-affiliated IVF center between Jan/2014 and Dec/2015. The influences of the cycles' characteristics on the number of gestational weeks to livebirth (GW), baby birth weight (BW), and baby birth length (BL) were evaluated by linear regression models, adjusted for maternal age and body mass index, number of transferred embryos, number of gestational sacs, and number of born infants...
February 12, 2019: JBRA Assisted Reproduction
Lucas Daniel Alcântara Borges, Vicente Ribeiro Rocha Júnior, Flávio Pinto Monção, Camila Soares, José Reinaldo Mendes Ruas, Fredson Vieira E Silva, João Paulo Sampaio Rigueira, Natanael Mendes Costa, Laura Lúcia Santos Oliveira, Walber de Oliveira Rabelo
Objective: This study ascertained effects of cactus pear in association with different roughage in the diet of F1 Holstein/Zebu cows on intake, nutrient digestibility, nitrogen balance, ingestive behavior and performance. Methods: Eight cows with 72 ± 11 days of lactation were used. The experimental design was simultaneous in two 4 x 4 Latin squares. Four experimental diets were used: Diet 1 - sorghum silage as exclusive roughage; Diet 2 - sorghum silage associated with cactus pear in a proportion of 50% of the roughage (dry basis); Diet 3 - elephant grass (Pennisetum purpureum cv...
February 9, 2019: Asian-Australasian Journal of Animal Sciences
Dulce Bento, Sandra Jesus, Filipa Lebre, Teresa Gonçalves, Olga Borges
Current vaccine research is mostly based on subunit antigens. Despite the better toxicity profile of these antigens they are often poorly immunogenic, so adjuvant association has been explored as a strategy to obtain a potent vaccine formulation. Recently, mast cell activators were recognized as a new class of vaccine adjuvants capable of potentiating mucosal and systemic immune responses. In this study, a co-adjuvanted delivery system was developed and characterized, combining the mast cell activator C48/80 with chitosan nanoparticles (Chi-C48/80 NPs), and the results were compared with plain chitosan nanoparticles...
February 9, 2019: Pharmaceutics
Jacob P Kelly, Brian J Andonian, Mahesh J Patel, Zhen Huang, Linda K Shaw, Robert W McGarrah, Salvador Borges-Neto, Eric J Velazquez, William E Kraus
OBJECTIVE: To identify temporal trends in the use of exercise treadmill testing (ETT) and cardiorespiratory fitness (CRF) estimated by ETT in metabolic equivalents (METs). PATIENTS AND METHODS: We compiled an ETT database of all available treadmill tests-including those with concomitant stress echocardiography and nuclear perfusion imaging studies-performed at Duke University Hospital from January 1, 1970- December 31, 2012. Six different ramp protocols were used in these combined modalities...
January 16, 2019: American Heart Journal
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