Ingrid Iara Damas, Luccas Lavareze, João Figueira Scarini, Reydson Alcides de Lima-Souza, Carolina Emerick, Mayara Trevizol Gonçalves, Tayná Figueiredo-Maciel, Gustavo de Souza Vieira, Talita de Carvalho Kimura, Iara Gonçalves Aquino, João Paulo Gonçalves de Paiva, My N Helms, Fernanda Viviane Mariano, Albina Altemani, Erika Said Abu Egal
Villitis of unknown etiology (VUE) is an inflammatory disease characterized by the infiltration of maternal CD8 +T cells into the placental villi. Although the pathogenesis of VUE is still debated, dysregulation of the immune system appears to be an important factor in the development of the disease. Interaction of maternal T cells with the fetal antigens seems to be the trigger for the VUE onset. In this context, graft vs host disease (GVHD) and allographic rejection seem to share similarities in the VUE immunopathological mechanism, especially those related to immunoregulation...
November 25, 2022: Placenta