pdcl2

The four new ligands, dialkyl esters of ( S , S )-propylenediamine- N , N '-di-(2,2'-di-(4-hydroxy-benzil))acetic acid (R2 - S , S -pddtyr·2HCl) (R = ethyl (L1), propyl (L2), butyl (L3), and pentyl (L4)) and corresponding palladium(II) complexes have been synthesized and characterized by microanalysis, infrared, 1 H NMR and 13 C NMR spectroscopy. In vitro cytotoxicity was evaluated using the MTT assay on four tumor cell lines, including mouse mammary (4T1) and colon (CT26), and human mammary (MDA-MD-468) and colon (HCT116), as well as non-tumor mouse mesenchymal stem cells...

Owing to their improved catalytic stability and ability to undergo repeated cycles, solid-supported catalysts show great potential for various catalytic reactions. In this study, we synthesized a catalyst comprising a palladium-2,2-bipyridine complex supported on TiO2 nanoparticles (TiO2 @BDP-PdCl2 ) fully characterised and investigated its efficacy in Suzuki-Miyaura cross coupling reactions involving phenyl boronic acid with various aryl halides under mild reaction conditions. The 2,2'- bipyridine (bp) has shown excellent complexation properties for Pd (II) and it could be easily anchored onto functionalized TiO2 support by the bridging carboxylate ions...

A Pd-catalyzed regioselective hydroarylation of terminal alkynes containing a heteroatom has been developed via carbopalladation for the synthesis of allylic ethers, amines, and homoallylic alcohols. Moreover, hydroalkenylation of alkynes produces a variety of stereodefined 1,4-dienes with high regioselectivity. The important features of the present protocol are that it is highly regioselective, operationally rapid, and scalable with a huge substrate scope using only 3 mol% of PdCl2 (PPh3 )2 catalyst in the presence of a mild base KOAc...

C-scorpionate metal complexes, specifically, [NiCl2 (tpm)]·3H2 O, [CoCl2 (tpm)]·3H2 O and [PdCl2 (tpm)] [tpm = hydrotris(1H-pyrazol-1-yl)methane], were effective in the N-formylation and N-methylation of amines using carbon dioxide, as carbon source, in the presence of sodium borohydride. Various parameters were studied, including reaction time, temperature, solvent volume, presence of additives, and catalyst amount. These parameters were found to have a significant impact on the selectivity of the product...

Despite decades of studies, a clear understanding of near- T g phenomena remains challenging for glass-forming systems. This review delves into the intricate molecular dynamics of the small, heterocyclic thioether, 6-methyl-2,3-dihydro-1,4-benzodithiine (MeBzS2 ), with a particular focus on its near- T g cold crystallization and relaxation mechanisms. Investigating isothermal crystallization kinetics at various temperatures reveals a significant interplay between its molecular dynamics and recrystallization from a supercooled liquid...

Rapid separation of low concentration palladium (Pd) from Pd-Platinum (Pt) coexisting systems remains a formidable challenge, primarily due to the undifferentiated substitution of ligands in Pd/Pt complexes by adsorption sites. The development of an adsorbent featuring monomer-specific affinity adsorption sites for Pd/Pt could mitigate this drawback. Herein, Manganese hexacyanoferrate (MnHCF) possessing the sensitivity and specificity to Pd ions (Pd(II)) was synthesized via the facile co-precipitation method...

The ( S )-(+)-1-(4-bromo-phen-yl)- N -[(4-methoxyphen-yl)methyl-idene]ethyl-amine ligand, C16 H16 BrNO, (I), was synthesized through the reaction of 4-meth-oxy-anisaldehyde with ( S )-(-)-1-(4-bromo-phen-yl)ethyl-amine. It crystallizes in the ortho-rhom-bic space group P 21 21 21 belonging to the Sohncke group, featuring a single mol-ecule in the asymmetric unit. The refinement converged successfully, achieving an R factor of 0.0508. The PdII com-plex bis-{( S )-(+)-1-(4-bromo-phen-yl)- N -[(4-methoxyphen-yl)methyl-idene]ethyl-amine-κ N }di-chlorido-pal-ladium(II), [PdCl2 (C16 H16 BrNO)2 ], (II), crystallizes in the monoclinic space group P 21 belonging to the Sohncke group, with two mol-ecules in the asymmetric unit...

To further enrich the coordination chemistry of hexaphyrins and probe the underlying property-structural correlations, N-confused dithiahexaphyrin(1.1.1.1.1.0) (1) with 26 π-electron Hückel aromaticity was synthesized. Based on its unprecedented two unsymmetrical cavities, five palladium complexes 2, 3, 4-Ph, 4-Cl and 5 have been successfully synthesized under various coordinations. Thus, two mono-Pd(ii) complexes 2 and 3 with the Pd(ii) atom coordinated in the two different cavities were obtained by treating 1 with palladium reagents PdCl2 , and (PPh3 )2 PdCl2 respectively...

The title complex, [PdCl2 (C9 H13 N)2 ], comprises a single mol-ecule in the asymmetric unit. The PdII atom is tetra-coordinated by two N atoms from two trans -aligned organic ligands and two Cl ligands, forming a square-planar metal coordination environment. The distances from the ortho -H atoms on the phenyl ring to the central PdII atom fall within the range 4.70-5.30 Å, precluding any significant intra-molecular Pd⋯H inter-actions.

E(hmds)(bqfam) (E = Ge ( 1a ), Sn ( 1b ); hmds = N(SiMe3 )2 , bqfam = N,N'-bis (quinol-8-yl)formamidinate), which are amidinatotetrylenes equipped with quinol-8-yl fragments on the amidinate N atoms, have been synthesized from the formamidine Hbqfam and Ge(hmds)2 or SnCl(hmds). Both 1a and 1b are fluxional in solution at room temperature, as the E atom oscillates from being attached to the two amidinate N atoms to being chelated by an amidinate N atom and its closest quinolyl N atom (both situations are similarly stable according to density functional theory calculations)...

The 2D heterometallic sodium-palladium(II) coordination polymers with 2-halonicotinates [2-chloropyridine-3-carboxylate (2-chloronicotinate), 2-Clnic- and 2-bromopyridine-3-carboxylate (2-bromonicotinate), 2-Brnic- ], {[Na2 (H2 O)2 (μ-H2 O)4 PdCl2 (μ-2-Clnic- N:O ')2 ]} n ( 1 ), and {[Na2 (H2 O)2 (μ-H2 O)4 PdBr2 (μ-2-Brnic- N:O ')2 ]·2H2 O} n ( 2 ) were prepared in aqueous solutions under the presence of NaHCO3 , while palladium(II) monomers with the neutral 2-chloronicotinic and 2-bromonicotinic acid ligands, [PdCl2 (2-ClnicH- N )2 ]·2DMF ( 3 ) and [PdCl2 (2-BrnicH- N )2 ]·2DMF ( 4 ), were prepared in DMF/water mixtures (DMF = N , N '-dimethylformamide)...

The search for alternatives to cisplatin has led to the development of new metal complexes where thiazoline derivatives based on platinum(II) and palladium(II) stand out. In this sense, the Pt(II) and Pd(II) complexes coordinated with the thiazoline derivative ligand 2-(3,4-dichlorophenyl)imino-N-(2-thiazolin-2-yl)thiazolidine (TdTn), with formula [PtCl2 (TdTn)] and [PdCl2 (TdTn)], have previously shown good results against several cancer lines; however, in this work, we have managed to improve their activity by supporting them on mesoporous silica nanoparticles (MSN)...

We present four proton-responsive palladium and platinum complexes, [MCl2(RPONNHO)] (M = Pd, Pt; R = iPr, tBu) synthesised by complexation of PdCl2 or PtCl2(COD) with the 1,8-naphthyridine ligand RPONNHO. Deprotonation of [MCl2(tBuPONNHO)] switches the ligand coordination from mono- to dinucleating, offering a synthetic pathway to bimetallic PdII and PtII complexes [M2Cl2(tBuPONNO)2]. Two-electron reduction gives planar MI-MI complexes [M2(tBuPONNO)2] (M = Pd, Pt) containing a metal-metal bond. In contrast to the related nickel system that forms a metallophosphorane [Ni2(tBuPONNOPONNO)], an unusual phosphinite binding mode is observed in [M2(tBuPONNO)2] containing close phosphinite-naphthyridinone P···O interactions, which is investigated spectroscopically, crystallographically and computationally...

The 1,2,4,5-tetrakis(alkylthio)benzenes are redox-active organosulfur molecules that support oxidation to a stable radical cation. Their utility as ligands for the assembly of multimetal complexes with tailored functionality/property is unexamined. Here, 1,2,4,5-tetrakis(isopropylthio)benzene (tptbz, 1 ) is shown to bind PdCl2 at either one end, leaving the other open, or at both ends to form centrosymmetric [Cl2 Pd(tptbz)PdCl2 ], 4 . Ligand metathesis between Na2 [(N≡C)2 C2 S2 ] (Na2 mnt) and [Cl2 M(tptbz)] (M = Pd, 2 ; M = Pt, 3 ) yields [(mnt)M(tptbz)] (M = Pd, 5 ; M = Pt, 6 ), but an alternative route involving transmetalation with [(mnt)SnMe2 ] delivers substantially greater yield...

Herein, we have reported synthesis of a macrocyclic organosulfur ligand (L1) having seventeen-membered macrocyclic ring. Subsequently, the corresponding trans-palladium complex (C1) of bulky macrocyclic organosulfur ligand was synthesized by reacting it with PdCl2(CH3CN)2 salt. The newly synthesized ligand and complex were characterized using various analytical and spectroscopic techniques such as 1H, 13C{1H} Nuclear Magnetic Resonance (NMR), Ultraviolet-visible (UV-Visible), Fourier Transform Infrared (FTIR) Spectroscopy, High-Resolution Mass Spectrometry (HRMS), and elemental analysis...

The development of a palladium catalyst that has enhanced catalytic performance, such as low aluminum cocatalyst loading, good copolymerization ability, high molecular weight, and excellent solubility of the (co)polymers, is still a challenge in norbornene copolymerizations. Here, a series of PdCl2 and PdMeCl complexes containing differently substituted anilines and imidazolidin-2-imine/guanidine ligands was successfully synthesized and characterized. X-ray diffraction analysis results revealed that these Pd complexes adopted an almost square-planar geometry, and the six-membered chelate ring showed structural distinctions as compared to traditional N^N-based α-diimine and β-diimine Pd complexes...

Nowadays, organic emitters suffer from insufficient electrochemiluminescence (ECL) efficiency in aqueous solutions, and their practical applications are severely restricted in the bio-sensing field. In this work, palladium nanospheres-embedded metal-organic frameworks (Pd@MOFs) were exploited to enhance the ECL efficiency of 2,6-dimethyl-8-(3-carboxyphenyl)4,4'-difluoroboradiazene (BET) prepared by a one-pot method in aqueous environment. First, the Pd@MOFs were generated via in situ reduction of Pd nanospheres anchored onto the MOFs, and fabricated by orderly coordination of palladium chloride (PdCl2 ) with 1,2,4,5-benzenetetramine (BTA) tetrahydrochloride...

Molecular folding regulation with environmental stimuli is critical in living and artificial molecular machine systems. Herein, we described a macrocycle, cyclo[4] (1,3-(4,6-dimethyl)benzene)[4](1,3-(4,6-dimethyl)benzene)(4-pyridine). Under 298 K, it has three stable stiff atropisomers with names as 1 (Cs symmetry), 2 (Cs symmetry), and 3 (C4v symmetry). At 393 K, 1 can reversibly transform into 2, but at 473 K, it can irrevocably transform into 3. At 338 K, 3 and (PhCN)2 PdCl2 complex to produce the metal-organic cage 4...

A analogous series of 2-(3,5-dimethylpyrazol-1-yl)phenyl substituted selenoether complexes of palladium [PdCl2 (RSeC6 H4 dmpz)]; (R = CH2 COOH (1), CH2 CH2 COOH (2), and CH2 CH2 OH (3); dmpz = dimethylpyrazole) were ably synthesized in a facile manner and exhaustively characterized. Insight into molecular structures of these complexes was keenly probed through single crystal X-ray diffraction (XRD) analysis, unfolding the structural scaffolds and laying into molecular aggregation, availed through hydrogen bonding interactions borne out of tethered protic groups...

An efficient synthesis of two pincer preligands [Ph2 PCH(R)ImCH2 CH2 CH2 PPh3 ]X2 (R = H, X = OTf; R = Ph, X = BF4 ) was developed. Subsequent reactions with PdCl2 and an excess of Cs2 CO3 led to the formation of highly stable cationic ortho- metalated Pd(II) complexes [( P , C , C , C )Pd]X exhibiting phosphine, NHC, phosphonium ylide, and σ-aryl donor extremities. The protonation of one of the latter complexes with R = H affords the Pd(II) complex [( P , C , C )Pd(MeCN)](OTf)2 bearing an unprecedented nonsymmetrical NHC core pincer scaffold with a 5,6-chelating framework...