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Chronic fatigue exercise

Ivan Peres Costa, Fabiano Politti, Lawrence P Cahalin, Etiene Farah Teixeira de Carvalho, Dirceu Costa, João Carlos Ferrari Corrêa, Rodolfo P Vieira, Manoel Carneiro Oliveira-Junior, Kátia De Angelis, Roberto Stirbulov, Simone Dal Corso, Paulo de Tarso de Carvalho, Nivaldo Antonio Parizotto, Ross Arena, LucianaMaria Malosá Sampaio
The aim of this study was to evaluate the effectiveness of acute application of LEDT in improving peripheral muscle performance during isometric exercise in patients with asthma. Eleven patients, with a mean age 38 ± 10, underwent a single LEDT and sham application in the femoral quadriceps' dominant member (cluster with 50 LED λ = 850 nm, 50 mW, 15 s; 37.5 J), 48 h apart in a randomized crossover design. Before and after LEDT and sham application, the patients were submitted an isometric endurance test (60% of the maximum isometric voluntary contraction), up to the limit of tolerance simultaneous recording of surface electromyography...
2019: BioMed Research International
T van der Zalm, J Alsma, S W E van de Poll, M W Wessels, N P Riksen, J Versmissen
Postural orthostatic tachycardia syndrome (POTS) is a condition in which a change from a supine to an upright position causes an abnormally large increase in heart rate which may be accompanied by a variety of physical complaints. We report two cases illustrating the heterogeneity of this syndrome. We give an update on the etiology of POTS, which is still poorly understood, and its overlap with other syndromes such as chronic fatigue syndrome. Clinicians should be aware of POTS, a fairly common clinical entity, that can result in significant impairments to a patient's quality of life...
January 2019: Netherlands Journal of Medicine
Rafael Calais Gaspar, Camilla Bertuzzo Veiga, Mariana Pereira Bessi, Marcella Neves Dátilo, Marcella Ramos Sant'Ana, Patrícia Brito Rodrigues, Leandro Pereira de Moura, Adelino Sanchez Ramos da Silva, Gustavo Aparecido Santos, Rodrigo Ramos Catharino, Eduardo Rochete Ropelle, José Rodrigo Pauli, Dennys Esper Cintra
GPR120 and GPR40 were recently reported as omega-3 (ω3) receptors with anti-inflammatory properties. Physical exercise could increase the expression of these receptors in the liver, improving hepatic metabolism in obesity and type 2 diabetes. Our aim was to investigate GPR120/40 in the liver of lean and obese mice after acute or chronic physical exercise, with or without the supplementation of ω3 rich flaxseed oil (FS), as well as assess the impact of exercise and FS on insulin signaling and inflammation...
December 12, 2018: Journal of Nutritional Biochemistry
Ho-Jin Shin, Sung-Hyeon Kim, Eun-Tae Jeon, Min-Goo Lee, Sung Jae Lee, Hwi-Young Cho
BACKGROUND: Chronic ankle instability (CAI) is a common disease following ankle sprain and appears balance and gait problems, pain, and fatigue. This study aimed to examine the effect of therapeutic exercise performed on sea sand on pain, fatigue, and balance ability in patients with CAI. METHODS: This study was designed as a randomized controlled trial. Subjects with a Cumberland Ankle Instability Tool (CAIT) score of less than 27 were selected. 22 subjects were randomly assigned to the sea sand (SS) group (n=11) or the self-management (SM) group (n=11)...
February 12, 2019: Journal of Sports Medicine and Physical Fitness
Sebastian Proschinger, Jens Freese
Feelings of fatigue not only occur in chronic and acute disease states, but also during prolonged strenuous exercise as a symptom of exhaustion. The underlying mechanisms of fatigue in diseases seem to rely on neuroinflammatory pathways. These pathways are interesting to understand exerciseinduced fatigue regarding immune system to brain signaling and effects of cerebral cytokines. Activation of the immune system incurs a high-energy cost, also in the brain. In consequence immune cells have high energetic priority over other tissues, such as neurons...
2019: Exercise Immunology Review
Thomas J Wilkinson, Emma L Watson, Douglas W Gould, Soteris Xenophontos, Amy L Clarke, Barbara P Vogt, João L Viana, Alice C Smith
Background: Chronic kidney disease (CKD) patients experience a high symptom burden including fatigue, sleep difficulties, muscle weakness and pain. These symptoms reduce levels of physical function (PF) and activity, and contribute to poor health-related quality of life (HRQoL). Despite the gathering evidence of positive physiological changes following exercise in CKD, there is limited evidence on its effect on self-reported symptom burden, fatigue, HRQoL and physical activity. Methods: Thirty-six patients [mean ± SD 61...
February 2019: Clinical Kidney Journal
Yuqiu Ye, Hongyong Liu, Yanbing Chen, Yunqiang Zhang, Shaomin Li, Wentao Hu, Rongqian Yang, Zhesi Zhang, Linsheng Lv, Xun Liu
BACKGROUND: Anemia is extremely common among dialysis patients and underlies some of the symptoms associated with reduced kidney function, including fatigue, depression, reduced exercise tolerance, and dyspnea. OBJECTIVES: A clearer cognition of the prognosistic impact of hemoglobin (Hb) or hematocrit (Hct) target for the outcomes of dialysis patients is urgent. This article aims to establish the suitable hemoglobin in order to provide clinical guidance. METHODS: MEDLINE, EmBase, the Cochrane Library and other databases were searched with both MeSH terms and keywords to gather randomized controlled trials that assessed all-cause mortality, cardiovascular events, fistula thrombosis, infectious diseases and transfusion among dialysis-dependent patients using erythropoiesis-stimulating agents...
November 2018: Renal Failure
David B Copithorne, Charles L Rice
PURPOSE: Blood flow restriction (BFR) with low-intensity (< 30% of 1 repetition maximum strength) muscle contraction has been used chronically (> 4 weeks) to enhance resistance training. However, mechanisms underlying muscle adaptations following BFR are not well understood. To explore changes related to chronic BFR adaptations, the current study used blood flow occlusion (BFO) during an acute bout of low-intensity isometric fatiguing contractions to assess peripheral (muscle) factors affected...
February 8, 2019: European Journal of Applied Physiology
Anna Kuo, Joshua J Todd, Jessica W Witherspoon, Tokunbor A Lawal, Jeffery Elliott, Irene C Chrismer, Monique O Shelton, Muslima S Razaqyar, Minal S Jain, Ruhi Vasavada, Melissa Waite, Bart Drinkard, Darren Michael, Alicia Richarte, Carsten G Bönnemann, Katherine G Meilleur
BACKGROUND: RYR1-related disorders (RYR1-RD), are a spectrum of genetic neuromuscular disorders. Affected individuals frequently experience fatigue yet appropriate tools to assess RYR1-RD-associated fatigue remain underdeveloped. OBJECTIVE: This study assessed the reliability and validity of two self-report questionnaires, the multidimensional fatigue inventory (MFI-20) and adult/pediatric functional assessment of chronic illness-fatigue (FACIT-F/Peds-FACIT-F) as potential fatigue measures in RYR1-RD affected individuals...
2019: Journal of Neuromuscular Diseases
Sojung Park, Ji Youn Kim, Jae Cheol Lee, Hyeong Ryul Kim, Seungjae Song, Hee Kwon, Wonjun Ji, Chang Min Choi
BACKGROUND: Advanced lung cancer patients often have chronic lung disease with reduced exercise capacities and various symptoms leading to altered quality of life (QoL). No studies have assessed pulmonary rehabilitation (PR) employing a mobile app and an Internet of Things device in advanced lung cancer patients undergoing chemotherapy. OBJECTIVE: This study aimed to determine the feasibility and efficacy of smartphone app-based PR on exercise capacity, symptom management, and QoL in patients with advanced lung cancer undergoing chemotherapy...
February 4, 2019: JMIR MHealth and UHealth
Andrea Polli, Jessica Van Oosterwijck, Jo Nijs, Uros Marusic, Inge De Wandele, Lorna Paul, Mira Meeus, Greta Moorkens, Luc Lambrecht, Kelly Ickmans
PURPOSE: Oxidative stress has been proposed as a contributor to pain in patients with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). During incremental exercise in patients with ME/CFS, oxidative stress enhances sooner and antioxidant response is delayed. We explored whether oxidative stress is associated with pain symptoms or pain changes following exercise, and the possible relationships between oxidative stress and parasympathetic vagal nerve activity in patients with ME/CFS versus healthy, inactive controls...
January 18, 2019: Clinical Therapeutics
Bhasker Amatya, Fary Khan, Mary Galea
BACKGROUND: Multiple sclerosis (MS) is a major cause of chronic, neurological disability, with a significant long-term disability burden, often requiring comprehensive rehabilitation. OBJECTIVES: To systematically evaluate evidence from published Cochrane Reviews of clinical trials to summarise the evidence regarding the effectiveness and safety of rehabilitation interventions for people with MS (pwMS), to improve patient outcomes, and to highlight current gaps in knowledge...
January 14, 2019: Cochrane Database of Systematic Reviews
Samira Tatiyama Miyamoto, Valéria Valim, Luciana Carletti, Wan-Fai Ng, Anselmo José Perez, Dennis William Lendrem, Michael Trennel, Raquel Altoé Giovelli, Laiza Hombre Dias, Érica Vieira Serrano, Alice Mendonça Subtil, Vanessa Cândido Abreu, Jamil Natour
OBJECTIVE: The aim of this study was to evaluate the safety and effectiveness of a supervised walking program in women with primary Sjögren's syndrome (pSS). METHODS: Forty-five sedentary women fulfilling the American European Consensus Criteria for pSS were randomized to a training group (TG, n = 23) or control group (CG, n = 22). Patients in the TG were submitted to supervise walking three times a week for 16 weeks. The patients of the CG were instructed to not perform any kind of regular physical exercise...
January 2, 2019: Rheumatology International
Kadirhan Ozdemir, Ilke Keser, Ilker Sen, M Ozgur Tan
OBJECTIVES: The aim of this study was to investigate the relationship between the parameters of fatigue, quality of life and leisure time physical activity in prostate cancer (PCa) patients. This is the first study in the literature to report interaction between these parameters from the perspective of physiotherapy and rehabilitation. MATERIALS AND METHODS: Fifty-eight out-patients were enrolled in this study. In an oncologic rehabilitation unit, Functional Assessment of Chronic Illness Therapy-Fatigue Questionnaire (FACIT-F), Functional Assessment of Cancer Therapy-Prostate Questionnaire (FACT-P) and Godin Leisure Time Exercise Questionnaire (GLTEQ) were utilized to evaluate fatigue, quality of life and physical activity, respectively...
December 14, 2018: Journal of Back and Musculoskeletal Rehabilitation
Suhani Patel, Aaron D Cole, Claire M Nolan, Ruth E Barker, Sarah E Jones, Samantha Kon, Julius Cairn, Michael Loebinger, Robert Wilson, William D-C Man
International guidelines recommend pulmonary rehabilitation for patients with bronchiectasis, supported by small trials and data extrapolated from chronic obstructive pulmonary disease (COPD). However, it is unknown whether real-life data on completion rates and response to pulmonary rehabilitation are similar between patients with bronchiectasis and COPD.Using propensity score matching, 213 consecutive patients with bronchiectasis referred for a supervised pulmonary rehabilitation programme were matched 1:1 with a control group of 213 patients with COPD...
January 2019: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
Ji Young Kim, Mi Kyung Lee, Dong Hoon Lee, Dong Woo Kang, Ji Hee Min, Ji Won Lee, Sang Hui Chu, Min Su Cho, Nam Kyu Kim, Justin Y Jeon
PURPOSE: To examine the effects of a home-based exercise program on quality of life (QOL), psychological health, and the level of physical activity (PA) in colorectal cancer survivors. METHODS: Seventy-one colorectal cancer survivors were randomized into either a home-based exercise group (N = 37) or control group (N = 34). The home-based exercise program included unsupervised walking, stationary bike, or swimming for aerobic exercise, as well as resistance exercise DVDs, a pedometer, and an exercise log...
December 18, 2018: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
K Gatt, J Schembri, K H Katsanos, D Christodoulou, K Karmiris, U Kopylov, C Pontas, I Koutrobakis, K Foteinogiannopoulou, A Fabian, T Molnar, D Zammit, M Fragaki, D Balomenos, N Zingboim, S Ben Horin, G J Mantzaris, P Ellul
Background and aims: IBD can impair the patients` functional capacity with significant negative effects on their quality of life. Our aim was to determine the impact of IBD diagnosis on fitness levels and to assess the levels of engagement in physical activity and fatigue in IBD patients` pre- and post- diagnosis. Methods: A prospective multi-centre cross-sectional study was performed. Patients diagnosed with IBD in the previous 18 months were recruited. Inclusion criteria included clinical remission and/or no treatment changes within the previous 6 months...
December 18, 2018: Journal of Crohn's & Colitis
Hironobu Hamada, Kiyokazu Sekikawa, Isao Murakami, Kouichi Aimoto, Kazuyoshi Kagawa, Tatsuya Sumigawa, Ken Okusaki, Takefumi Dodo, Yoshikazu Awaya, Masatoshi Watanabe, Keiichi Kondo, Takashi Ogawa, Hikaru Yamamoto, Noboru Hattori
Chronic obstructive pulmonary disease (COPD) has significant systemic effects, such as weight loss, which affects exercise capacity, health-related quality of life (HRQOL) and survival. The traditional herbal medicine, Hochuekkito (TJ-41), improves the nutritional status and decreases systemic inflammation in patients with COPD. However, to date, the additive effect of TJ-41 on pulmonary rehabilitation (PR) in patients with COPD has not been researched comprehensively. The purpose of the present study was to investigate the efficacy and safety of adding TJ-41 to PR for patients with COPD...
December 2018: Experimental and Therapeutic Medicine
Frank Rassouli, David Boutellier, Jonas Duss, Stephan Huber, Martin H Brutsche
Background: Concerning COPD, pulmonary rehabilitation (PR) has a positive effect on disease progression and mortality, is cost-effective, and is a part of recommendations of international guidelines. Only a minority of patients profit from conventional PR due to a lack of resources, physicians' guideline adherence, or patients' motivation. Novel digital therapies like Kaia COPD, a smartphone application that digitizes PR in COPD, are promising solutions to fill this void. Methods: Kaia COPD provides a digital version of PR and is certified as a class-I medical device in the European Union...
2018: International Journal of Chronic Obstructive Pulmonary Disease
Charlotte Grootaers, Mieke Roggen, Marc Gewillig
A 5-year-old girl presented with chronic fatigue and extreme exercise intolerance. After countless doctor visits, investigations, and hospital admissions, striking desaturation during exercise test pointed to a cardiovascular problem. Desaturation as a result of right-to-left shunting through a patent foramen ovale during upright exercise was hypothesised. A cardiac catheterisation confirmed the presence of an unusually cranially located patent foramen ovale; the defect was subsequently closed. Physical re-evaluation 6 weeks later showed spectacular physical and mental improvement and stabile saturation during exercise...
December 11, 2018: Cardiology in the Young
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