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Pulmonary hypertension CKD

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https://read.qxmd.com/read/30662059/treatment-of-hypertensive-cardiogenic-edema-with-intravenous-high-dose-nitroglycerin-in-a-patient-presenting-with-signs-of-respiratory-failure-a-case-report-and-review-of-the-literature
#1
Fermín López-Rivera, Hector R Cintrón Martínez, Christian Castillo LaTorre, Alexis Rivera González, Jose Gabriel Rodríguez Vélez, Vanessa Fonseca Ferrer, Omar F Méndez Meléndez, Edgar J Vázquez Vargas, Hernán A González Monroig
BACKGROUND Pulmonary edema is the accumulation of fluid in the lung secondary to increased hydrostatic pressure. Hypertensive cardiogenic pulmonary edema presents with a sudden onset of severe dyspnea, tachycardia, and tachypnea, and can occur when the systolic blood pressure exceeds 160 mmHg in association with acute decompensated congestive cardiac failure (CCF). A case is presented of hypertensive cardiogenic pulmonary edema treated with high-dose nitroglycerin and includes a review of the literature. CASE REPORT A 63-year-old Hispanic male with a medical history of hypertension, coronary artery disease, heart failure with a reduced ejection fraction of 35%, chronic kidney disease (CKD) and diabetes mellitus, presented as an emergency with acute, severe dyspnea...
January 21, 2019: American Journal of Case Reports
https://read.qxmd.com/read/30650039/chronic-kidney-disease-predicts-atrial-fibrillation-in-patients-with-st-segment-elevation-myocardial-infarction-treated-by-primary-percutaneous-coronary-intervention
#2
Răzvan Constantin Șerban, Ioana Șuș, Eva Katalin Lakatos, Zoltan Demjen, Alexandru Ceamburu, Paul Ciprian Fișcă, Cristina Somkereki, Laszlo Hadadi, Alina Scridon
BACKGROUND: Atrial fibrillation (AF) often complicates ST-segment elevation myocardial infarction (STEMI). Predictors of AF in this setting include factors related to the acute phase of STEMI and pre-existing conditions. More recently, novel AF predictors have been identified in the general population. We aimed to assess the ability of such novel factors to predict STEMI-related AF. METHODS: Data were collected from STEMI patients treated by primary PCI. Factors related to the acute phase of STEMI (Killip class, heart rate, blood pressure on admission, post-PCI TIMI flow), classic (age, hypertension, heart failure, previous myocardial infarction), and more novel (body mass index [BMI], diabetes, chronic kidney disease [CKD], chronic obstructive pulmonary disease [COPD]) AF predictors were evaluated...
January 16, 2019: Acta Cardiologica
https://read.qxmd.com/read/30648697/differences-in-clinical-characteristics-and-one-year-outcomes-of-hospitalized-heart-failure-patients-in-succeeding-european-society-of-cardiology-heart-failure-registries-pilot-and-long-term
#3
Paweł Balsam, Krzysztof Ozierański, Agnieszka Kapłon-Cieślicka, Sonia Borodzicz, Agata Tymińska, Michał Peller, Michał Marchel, Maria G Crespo-Leiro, Aldo Pietro Maggioni, Jarosław Drożdż, Grzegorz Opolski, Marcin Grabowski
INTRODUCTION The management of heart failure (HF) has significantly changed in recent decades. OBJECTIVES The paper analyzes clinical profile, one-year outcomes, predictors of mortality and hospital readmissions in hospitalized patients enrolled in the European Society of Cardiology HF-Pilot (ESC-HF-Pilot) and HF-Long Term (ESC-HF-LT) Registries. PATIENTS AND METHODS The analysis included hospitalized Polish patients from the ESC-HF-Pilot and ESC-HF-LT Registries. The primary endpoint (PE) was all-cause death at one year, whereas the secondary endpoint (SE) consisted of all-cause death or hospitalization for worsening HF at one year...
January 16, 2019: Polish Archives of Internal Medicine
https://read.qxmd.com/read/30642023/sex-differences-in-the-pattern-of-comorbidities-functional-independence-and-mortality-in-elderly-inpatients-evidence-from-the-reposi-register
#4
Salvatore Corrao, Christiano Argano, Giuseppe Natoli, Alessandro Nobili, Gino Roberto Corazza, Pier Mannuccio Mannucci, Francesco Perticone
BACKGROUND: The RePoSi study has provided data on comorbidities, polypharmacy, and sex dimorphism in hospitalised elderly patients. METHODS: We retrospectively analysed data collected from the 2010, 2012, 2014, and 2016 data sets of the RePoSi register. The aim of this study was to explore the sex-differences and to validate the multivariate model in the entire dataset with an expanded follow-up at 1 year. RESULTS: Among 4714 patients, 51% were women and 49% were men...
January 12, 2019: Journal of Clinical Medicine
https://read.qxmd.com/read/30600581/the-metabolic-syndrome-and-its-components-are-differentially-associated-with-chronic-diseases-in-a-high-risk-population-of-350-000-adults-a-cross-sectional-study
#5
Hana'a Rayyan Assi, Arnona Ziv, Rachel Dankner
AIMS: We compared strengths of associations conferred by the metabolic syndrome (MetS) and its components across four chronic disease categories (cancer, cardiovascular diseases [CVDs], chronic kidney disease [CKD], and chronic obstructive pulmonary disease [COPD]) in a community-dwelling high-risk population. METHODS: This is a cross-sectional analysis of Israeli adults insured in a single health maintenance organization during 2010 to 2013 and having greater than or equal to two MetS components (hypertension, dysglycemia, low high-density lipoprotein level, high plasma triglyceride level, and obesity)...
January 1, 2019: Diabetes/metabolism Research and Reviews
https://read.qxmd.com/read/30565874/pulmonary-hypertension-predicts-adverse-outcomes-in-renal-patients-a-systematic-review-and-meta-analysis
#6
Davide Bolignano, Anna Pisano, Giuseppe Coppolino, Giovanni Luigi Tripepi, Graziella D'Arrigo
In the general population and in heart disease, pulmonary hypertension (PH) is a strong and independent risk factor for mortality and adverse cardiovascular outcomes. We performed a systematic review and meta-analysis of longitudinal cohort studies of individuals with chronic kidney disease (CKD) of any-stage (also including end-stage kidney disease and kidney transplantation) stratified according to presence/absence of PH. Eighteen eligible studies (10 740 participants) were retrieved. PH had an overall pooled prevalence of 33% (95% CI 28-42) and portended a higher risk of all-cause mortality (RR 2...
November 22, 2018: Therapeutic Apheresis and Dialysis
https://read.qxmd.com/read/30534516/chronic-kidney-disease-in-the-emergency-centre-a-prospective-observational-study
#7
Babawale Taslim Bello, Olalekan Ezekiel Ojo, Olapeju Funke Oguntunde, Adedotun Ademola Adegboye
Introduction: Late presentation, usually to the emergency centre (EC), is frequently reported among patients with chronic kidney disease (CKD) in resource-limited settings, and is known to be associated with poor outcomes. This study aims to describe the pattern of EC presentation of adults with CKD in Southwest Nigeria. Methods: This was a prospective observational study of 158 consecutively presenting CKD patients at the EC of two tertiary hospitals in Southwest Nigeria...
December 2018: African Journal of Emergency Medicine Revue Africaine de la Médecine D'urgence
https://read.qxmd.com/read/30473936/a-divergence-between-underlying-and-final-causes-of-death-in-selected-conditions-an-analysis-of-death-registries-in-peru
#8
Rodrigo M Carrillo-Larco, Antonio Bernabe-Ortiz
Background: The underlying cause of death is used to study country and global mortality trends and profiles. The final cause of death could also inform the ultimately cause of death in individuals with underlying conditions. Whether there is a pattern between the underlying and final cause of death has not been explored using national death registries. We studied what final causes of death were most common among selected underlying causes using national death registries in Peru, 2015...
2018: PeerJ
https://read.qxmd.com/read/30306876/effects-of-pulmonary-hypertension-and-right-ventricular-function-in-short-and-long-term-kidney-function
#9
Mario Naranjo, Kevin Bryan Lo, Kenechukwu Mezue, Janani Rangaswami
Pulmonary hypertension is not uncommon in patients with renal disease and vice versa; therefore, influences treatments and outcomes. There is a large body of literature on pulmonary hypertension in patients with kidney disease, its prognostic implications, economic burden, and management strategies. However, the converse, namely the hemodynamic effects of pulmonary hypertension on kidney function (acute and chronic kidney injury) is less studied and described. There is also increasing interest in the effects of pulmonary hypertension on kidney transplant outcomes...
October 8, 2018: Current Cardiology Reviews
https://read.qxmd.com/read/29861563/a-prospective-study-of-pulmonary-hypertension-in-patients-with-chronic-kidney-disease-a-new-and-pernicious-complication
#10
H Suresh, B S Arun, V Moger, P B Vijayalaxmi, K T K Murali Mohan
Pulmonary hypertension (PH) is a recently recognized complication of chronic kidney disease (CKD), especially in end-stage renal disease. It has prevalence estimates of 30%-50% and is an independent predictor of increased mortality in CKD patients. The aim of this study is to analyze the prevalence of PH in patients with CKD, its severity in different stages of CKD, and risk factors for it. One hundred and eight patients with CKD treated at Karnataka Institute of Medical Sciences, Hubli, Karnataka, between January 1, 2014, and June 30, 2015, were selected...
March 2018: Indian Journal of Nephrology
https://read.qxmd.com/read/29781842/application-of-echocardiographic-data-in-patients-with-chronic-kidney-disease
#11
REVIEW
Ruth F Dubin
PURPOSE OF REVIEW: Patients with chronic kidney disease (CKD) are at a high risk for cardiovascular events and mortality, particularly heart failure. Echocardiography is the most commonly used diagnostic imaging modality for heart failure. The purpose of this review is to summarize recent literature that demonstrates how echocardiography may be used to define cardiac structure and function in the CKD population and to identify echocardiographic abnormalities that have utility in predicting clinical outcomes in this population...
July 2018: Current Opinion in Nephrology and Hypertension
https://read.qxmd.com/read/29582339/prevalence-of-pulmonary-hypertension-in-patients-with-chronic-kidney-disease-without-dialysis-a-meta-analysis
#12
Weifeng Shang, Yuanyuan Li, Yali Ren, Wei Li, HongLan Wei, Junwu Dong
PURPOSE: Recent epidemiological evidence attempts to demonstrate the risk of pulmonary hypertension (PH) among patients with chronic kidney disease (CKD) without dialysis, but prevalence estimates of PH in CKD without dialysis vary widely in the existing studies. This meta-analysis was to summarize the point prevalence of PH in adults with CKD without dialysis. METHODS: PubMed, EMBASE, the Cochrane Collaboration, and the reference lists of relevant articles were searched to identify eligible studies...
August 2018: International Urology and Nephrology
https://read.qxmd.com/read/29554879/epidemiology-and-risk-factors-in-ckd-patients-with-pulmonary-hypertension-a-retrospective-study
#13
Qian Zhang, Le Wang, Hongbing Zeng, Yongman Lv, Yi Huang
BACKGROUND: Pulmonary hypertension (PH) is a rare disease often associated with high mortality and is recently recognized as a common complication secondary to chronic kidney disease (CKD). Epidemiological data for this disorder across the spectrum of CKD is poorly understood. METHODS: We retrospectively analyzed 705 CKD patients with complete clinical records from July 2013 to September 2015. All the patients were estimated by echocardiography and PH was defined as pulmonary artery systolic pressure (PASP) > 35 mmHg...
March 20, 2018: BMC Nephrology
https://read.qxmd.com/read/29471290/presence-of-kidney-disease-as-an-outcome-predictor-in-patients-with-pulmonary-arterial-hypertension
#14
Laurent Bitker, Florence Sens, Cécile Payet, Ségolène Turquier, Antoine Duclos, Vincent Cottin, Laurent Juillard
BACKGROUND: Pulmonary arterial hypertension (PAH) may lead to right heart failure and subsequently alter glomerular filtration rates (GFR). Chronic kidney disease (CKD, GFR <60 mL/min/1.73 m2) may also adversely affect PAH prognosis. This study aimed to assess how right heart hemodynamics was associated with reduced estimated GFR (eGFR) and the association of CKD with survival in PAH patients. METHODS: In a prospective PAH cohort (2003-2012), invasive hemodynamics and eGFR were collected at diagnosis (179 patients) and during follow-up (159 patients)...
2018: American Journal of Nephrology
https://read.qxmd.com/read/29429751/pulmonary-hypertension-mortality-and-cardiovascular-disease-in-ckd-and-esrd-patients-a-systematic-review-and-meta-analysis
#15
Mengyao Tang, Jonathan A Batty, Chiayu Lin, Xiaohong Fan, Kevin E Chan, Sahir Kalim
BACKGROUND: Pulmonary hypertension is common in patients with chronic kidney disease (CKD) and end-stage renal disease (ESRD) and may be associated with poor outcomes. The magnitude of the association between pulmonary hypertension and mortality is uncertain due to the small size and variable findings of observational studies. STUDY DESIGN: Systematic review and meta-analysis of observational studies using subgroup analyses and metaregression. SETTING & POPULATION: Patients with ESRD or earlier stages of CKD...
July 2018: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://read.qxmd.com/read/29245978/chronic-kidney-disease-is-associated-with-a-risk-of-higher-mortality-following-total-knee-arthroplasty-in-diabetic-patients-a-nationwide-population-based-study
#16
Liang-Tseng Kuo, Su-Ju Lin, Chi-Lung Chen, Pei-An Yu, Wei-Hsiu Hsu, Tien-Hsing Chen
Diabetes and chronic kidney disease (CKD) are associated with a higher rate of complications in patients undergoing total knee arthroplasty (TKA). The purpose of this study was to determine the effects of CKD and diabetes in patients after TKA. Diabetic patients who received unilateral primary TKA between January 2008 and December 2011 were enrolled. The follow-up period was more than 6 months. The primary outcome was a TKA-related infection and the secondary outcome was all-cause mortality. The study cohort included 13844 patients who were followed for a mean period of 2 years, of whom 1459 (10...
November 21, 2017: Oncotarget
https://read.qxmd.com/read/29243213/accuracy-of-co-morbidity-data-in-patients-undergoing-abdominal-wall-hernia-repair-a-retrospective-study
#17
S Hajibandeh, S Hajibandeh, R Deering, D McEleney, J Guirguis, S Dix, A Sreh, E Toner, A El Muntasar, A Kausar, G Sheikh, D OShea, A Shafiq, A Kelly, A Khan, D Arumugam, A Evans
OBJECTIVES: To determine the baseline accuracy, sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of routinely collected co-morbidity data in patients undergoing abdominal wall hernia repair. METHODS: All patients aged > 18 who underwent umbilical, para-umbilical, inguinal or incisional hernia repair between 1 January 2015 and 1 November 2016 were identified. All parts of the clinical notes were searched for co-morbidities by two authors independently...
April 2018: Hernia: the Journal of Hernias and Abdominal Wall Surgery
https://read.qxmd.com/read/29174533/impact-of-declining-renal-function-on-outcomes-in-pulmonary-arterial-hypertension-a-reveal-registry-analysis
#18
Murali M Chakinala, Daniel W Coyne, Raymond L Benza, Adaani E Frost, Michael D McGoon, Brian K Hartline, Robert P Frantz, Mona Selej, Carol Zhao, David R Mink, Harrison W Farber
BACKGROUND: Renal dysfunction is associated with abnormal cardiopulmonary hemodynamics, in-hospital death and poor survival in patients with pulmonary arterial hypertension (PAH), and thus it may be a prognostic biomarker. In our analysis we assess the relationship between change in estimated glomerular filtration rate (eGFR) and outcomes in PAH patients in the Registry to Evaluate Early and Long-term PAH Disease Management (REVEAL). METHODS: Overall 2,368 patients were classified into chronic kidney disease (CKD) stages based on baseline eGFR: normal or Stages 1 or 2 (n = 1,699); Stage 3a (n = 399); Stage 3b (n = 196); and Stages 4 or 5 (n = 74)...
June 2018: Journal of Heart and Lung Transplantation
https://read.qxmd.com/read/28910330/quality-of-life-measures-predict-cardiovascular-health-and-physical-performance-in-chronic-renal-failure-patients
#19
A Rogan, K McCarthy, G McGregor, T Hamborg, G Evans, S Hewins, N Aldridge, S Fletcher, N Krishnan, R Higgins, D Zehnder, S M Ting
BACKGROUND: Patients with advanced chronic kidney disease (CKD) experience complex functional and structural changes of the cardiopulmonary and musculoskeletal system. This results in reduced exercise tolerance, quality of life and ultimately premature death. We investigated the relationship between subjective measures of health related quality of life and objective, standardised functional measures for cardiovascular and pulmonary health. METHODS: Between April 2010 and January 2013, 143 CKD stage-5 or CKD5d patients (age 46...
2017: PloS One
https://read.qxmd.com/read/28869934/typical-hemodialysis-in-india-a-case-report
#20
Georgi Abraham, Madhusudan Vijayan, Milly Mathew
We report here a typical case of a patient on hemodialysis (HD) for end-stage renal disease (ESRD) in India that highlights some of the management issues encountered in a country with an enormous burden of ESRD and major challenges of underdialysis and management of comorbidities. The patient, a 42-year-old multiparous woman with chronic kidney disease (CKD) stage V, type 2 diabetes mellitus, and hypertension is a homemaker from a middle-class family, living in a large city, with no family history of CKD. From May 2013 to December 2016, she has been receiving twice-weekly maintenance HD for 4 h (intermittent HD); access was via an internal jugular line initially and then via a left brachiocephalic arteriovenous fistula (AVF) from late June 2013...
2017: Blood Purification
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