keyword
https://read.qxmd.com/read/38535596/the-influence-of-l-lysine-alpha-oxidase-on-the-biofilm-formation-of-opportunistic-microorganisms-associated-with-inflammatory-diseases-of-the-urinary-tract
#21
JOURNAL ARTICLE
Alexandr Senyagin, Nadezhda Sachivkina, Milana Das, Anna Arsenyuk, Ramziya Mannapova, Alfir Mannapov, Tursumbai Kubatbekov, Dmitriy Svistunov, Olesya Petrukhina, Andrey Zharov, Natallia Zhabo
Urinary tract infections occupy a special niche among diseases of infectious etiology. Many microorganisms associated with urinary tract infections, such as Klebsiella oxytoca , Enterococcus spp., Morganella morganii , Moraxella catarrhalis , Pseudomonas aeruginosa , Proteus mirabilis , Staphylococcus aureus , Staphylococcus spp., and Candida spp., can form biofilms. The aim of this research was to study the effect of the enzyme L-lysine-Alpha-oxidase (LO) produced by the fungus Trichoderma harzianum Rifai on the biofilm formation process of microorganisms associated with urinary tract infections...
March 15, 2024: Pathogens
https://read.qxmd.com/read/38535588/canine-schistosomiasis-in-the-west-coast-heterobilharzia-americana-in-two-natural-intermediate-hosts-found-in-the-colorado-river-california
#22
JOURNAL ARTICLE
Anil Baniya, Connor J Goldy, Jiranun Ardpairin, Perla Achi, Yu Wei Chang, Rose C Adrianza, Apichat Vitta, Adler R Dillman
The emergence of infectious diseases presents a significant global health, economic, and security risk. Climate change can unexpectedly lead to the spread of pathogens, vectors, or hosts into new areas, contributing to the rise of infectious diseases. Surveillance plays a crucial role in monitoring disease trends and implementing control strategies. In this study, we document the first discovery of Heterobilharzia americana , a parasitic schistosome of mammals and its intermediate hosts Galba cubensis and Galba humilis along the banks of the Colorado River in California...
March 13, 2024: Pathogens
https://read.qxmd.com/read/38535563/lung-microbiota-and-ventilator-associated-pneumonia-in-the-neonatal-period
#23
REVIEW
Fermín García-Muñoz Rodrigo, Lourdes Urquía Martí, Marta Siguero Onrubia, Moreyba Borges Luján, Gloria Galán Henríquez, Desiderio Reyes Suárez
The lung microbiota is a complex community of microorganisms that colonize the respiratory tract of individuals from, or even before, birth. Although the lungs were traditionally believed to be sterile, recent research has shown that there is a diversity of bacterial species in the respiratory system. Knowledge about the lung microbiota in newborns and its relationship with bacterial infections is of vital importance to understand the pathogenesis of respiratory diseases in neonatal patients undergoing mechanical ventilation...
March 1, 2024: Pathogens
https://read.qxmd.com/read/38535543/prenatal-maternal-immunization-for-infant-protection-a-review-of-the-vaccines-recommended-infant-immunity-and-future-research-directions
#24
REVIEW
Elizabeth M Quincer, Lisa M Cranmer, Satoshi Kamidani
Prenatal maternal immunization is an effective tool to protect mothers and infants from poor health outcomes due to infectious diseases. We provide an overview of the rationale for the use of prenatal vaccines, discuss the immunologic environment of the maternal-fetal interface including the impact of maternal vaccines prenatally and subsequently on the infant's immune response, and review vaccines currently recommended in pregnancy and landscape for the future of maternal vaccination. This review aims to provide an understanding of the recent history and progress made in the field and highlight the importance of continued research and development into new vaccines for pregnant populations...
February 23, 2024: Pathogens
https://read.qxmd.com/read/38535510/clinical-characteristics-of-118-pediatric-patients-with-acute-benign-myositis-associated-with-influenza-a-virus-infection
#25
JOURNAL ARTICLE
Shaoqun Jiang, Jieling Li, Jie Cao, Yuexu Ou, Yuanhui Duan, Xiaoming Gan
OBJECTIVE: The objective of this study was to investigate the clinical and laboratory features of acute benign myositis associated with influenza A virus infection in children. METHODS: A retrospective analysis was performed on the clinical data of 118 children with acute benign myositis associated with influenza A virus infection who were admitted to the Children's Hospital of Chongqing Medical University during the epidemic period of influenza A from February 2023 to May 2023...
March 27, 2024: Pediatric Infectious Disease Journal
https://read.qxmd.com/read/38535409/a-phase-three-study-of-the-safety-and-immunogenicity-of-a-four-dose-series-of-20-valent-pneumococcal-conjugate-vaccine-in-healthy-infants
#26
JOURNAL ARTICLE
Shelly Senders, Nicola P Klein, Noor Tamimi, Allison Thompson, Gary Baugher, James Trammel, Yahong Peng, Peter Giardina, Ingrid L Scully, Michael Pride, Kimberly J Center, William C Gruber, Daniel A Scott, Wendy Watson
BACKGROUND: The 20-valent pneumococcal conjugate vaccine (PCV20) was developed to extend pneumococcal disease protection beyond 13-valent PCV (PCV13). METHODS: This phase 3, double-blind study conducted in the United States/Puerto Rico evaluated PCV20 safety and immunogenicity. Healthy infants were randomized to receive a 4-dose series of PCV20 or PCV13 at 2, 4, 6 and 12-15 months old. Objectives included demonstrating noninferiority (NI) of PCV20 to PCV13 immunoglobulin G (IgG) geometric mean concentrations after doses 3 and 4 and percentages of participants with predefined IgG concentrations after dose 3, with 7 additional PCV20 serotypes compared with the lowest result among vaccine serotypes in the PCV13 group...
March 26, 2024: Pediatric Infectious Disease Journal
https://read.qxmd.com/read/38535212/description-and-pathogenicity-of-colletotrichum-kapreanum-sp-nov-a-cherelle-wilt-pathogen-belonging-to-the-gigasporum-species-complex
#27
JOURNAL ARTICLE
Yoshiki Takata, Celynne Ocampo-Padilla, Mike Andre C Malonzo, Dan Charlie Joy Camara Pangilinan, Shunsuke Nozawa, Kyoko Watanabe
Similar to cacao pod rot, cherelle wilt decreases production from cacao fields. Among all known fungal pathogens of the cacao, Colletotrichum spp. are common infectious agents that affect the cherelles and pods of cacao; thus, cacao diseases are often classified by stage. Therefore, knowing whether these pathogens are common in both fruit stages is necessary for implementing disease control measures. Symptoms of cherelle wilt were found in cacao plants in Pangasinan, Philippines, in 2022. The fungal strain obtained from the lesion was found to be pathogenic towards cherelles, but not towards pods...
March 8, 2024: Journal of Fungi (Basel, Switzerland)
https://read.qxmd.com/read/38535131/cardiometabolic-risk-profiles-of-adolescents-living-with-perinatally-acquired-hiv-in-south-africa
#28
JOURNAL ARTICLE
Leonore Greybe, Shaun Barnabas, Mark Cotton, Penelope Rose, Helena Rabie, Lisa Frigati
BACKGROUND: We assessed the Pathological Determinants of Atherosclerosis in Youth (PDAY) score and other potential cardiovascular disease risk factors in adolescents previously enrolled in the Children with HIV Early antiRetroviral (CHER) and International Maternal Pediatric Adolescent AIDS Clinical Trials Network P1060 clinical trials. METHODS: Coronary artery and abdominal aorta (AA) PDAY scores were calculated for 56 participants over 15 years of age using a weighted combination of dyslipidemia, cigarette smoking, hypertension, obesity, and hyperglycemia...
March 26, 2024: Pediatric Infectious Disease Journal
https://read.qxmd.com/read/38535091/enterococcal-central-nervous-system-infections-in-children-a-22-years-experience-in-a-tertiary-center-and-review-of-the-literature
#29
JOURNAL ARTICLE
Aviad Schnapp, Sergei Elber-Dorozko, Violeta Temper, Oren Gordon, Dina Averbuch
BACKGROUND: Enterococcal meningitis in children is rare, and its clinical presentation, laboratory characteristics and outcomes are not well defined. METHODS: We conducted a retrospective analysis of Enterococcal meningitis cases during 2002-2023 at our tertiary center. RESULTS: We identified 10 cases in children aged 2 weeks to 15 years (median age: 8 months). Seven children were males and 9 had comorbidities, including a ventriculoperitoneal shunt in 5 children...
March 26, 2024: Pediatric Infectious Disease Journal
https://read.qxmd.com/read/38535089/prevalence-of-atopic-disorders-among-pediatric-patients-with-pulmonary-and-disseminated-coccidioidomycosis
#30
JOURNAL ARTICLE
Sarah Zhang, Brenna LaBere, James V Woodward, Wassim Ballan, Katherine W Perry, Keith Sacco
Type 2 inflammatory responses are associated with worse prognosis in coccidioidomycosis. It is unclear whether patients with preexisting type 2 inflammation and atopic disorders are predisposed to disseminated coccidioidomycosis. A retrospective analysis of pediatric patients with disseminated coccidioidomycosis revealed no significant difference in the history of atopic disorders or eosinophilia as compared to those with isolated pulmonary disease. Tissue-specific type 2 responses may still play a role in coccidioidomycosis immune dysregulation, and further investigation is needed...
March 22, 2024: Pediatric Infectious Disease Journal
https://read.qxmd.com/read/38535044/denguefog-a-fog-computing-enabled-weighted-random-forest-based-smart-health-monitoring-system-for-automatic-dengue-prediction
#31
JOURNAL ARTICLE
Ashima Kukkar, Yugal Kumar, Jasminder Kaur Sandhu, Manjit Kaur, Tarandeep Singh Walia, Mohammed Amoon
Dengue is a distinctive and fatal infectious disease that spreads through female mosquitoes called Aedes aegypti. It is a notable concern for developing countries due to its low diagnosis rate. Dengue has the most astounding mortality level as compared to other diseases due to tremendous platelet depletion. Hence, it can be categorized as a life-threatening fever as compared to the same class of fevers. Additionally, it has been shown that dengue fever shares many of the same symptoms as other flu-based fevers...
March 15, 2024: Diagnostics
https://read.qxmd.com/read/38535038/tumor-like-lesions-in-primary-angiitis-of-the-central-nervous-system-the-role-of-magnetic-resonance-imaging-in-differential-diagnosis
#32
REVIEW
Marialuisa Zedde, Manuela Napoli, Claudio Moratti, Claudio Pavone, Lara Bonacini, Giovanna Di Cecco, Serena D'Aniello, Ilaria Grisendi, Federica Assenza, Grégoire Boulouis, Thanh N Nguyen, Franco Valzania, Rosario Pascarella
Primary Angiitis of the Central Nervous System (PACNS) is a rare disease and its diagnosis is a challenge for several reasons, including the lack of specificity of the main findings highlighted in the current diagnostic criteria. Among the neuroimaging pattern of PACNS, a tumefactive form (t-PACNS) is a rare subtype and its differential diagnosis mainly relies on neuroimaging. Tumor-like mass lesions in the brain are a heterogeneous category including tumors (in particular, primary brain tumors such as glial tumors and lymphoma), inflammatory (e...
March 14, 2024: Diagnostics
https://read.qxmd.com/read/38535020/merging-two-models-of-one-dimensional-convolutional-neural-networks-to-improve-the-differential-diagnosis-between-acute-asthma-and-bronchitis-in-preschool-children
#33
JOURNAL ARTICLE
Waleed Salih, Hakan Koyuncu
(1) Background: Acute asthma and bronchitis are common infectious diseases in children that affect lower respiratory tract infections (LRTIs), especially in preschool children (below six years). These diseases can be caused by viral or bacterial infections and are considered one of the main reasons for the increase in the number of deaths among children due to the rapid spread of infection, especially in low- and middle-income countries (LMICs). People sometimes confuse acute bronchitis and asthma because there are many overlapping symptoms, such as coughing, runny nose, chills, wheezing, and shortness of breath; therefore, many junior doctors face difficulty differentiating between cases of children in the emergency departments...
March 12, 2024: Diagnostics
https://read.qxmd.com/read/38534973/the-role-of-oxidative-stress-in-tb-meningitis-and-therapeutic-options
#34
REVIEW
John Dawi, Aishvaryaa Shree Mohan, Yura Misakyan, Scarlet Affa, Edgar Gonzalez, Karim Hajjar, David Nikoghosyan, Sabrina Fardeheb, Christopher Tuohino, Vishwanath Venketaraman
Meningitis is an inflammatory condition affecting the meninges surrounding the brain and spinal cord. Meningitis can be triggered by various factors, including infectious agents like viruses and bacteria and non-infectious contributors such as cancer or head injuries. The impact of meningitis on the central nervous system involves disruptions in the blood-brain barrier, cellular infiltrations, and structural alterations. The clinical features that differentiate between tuberculous meningitis (TBM) and non-tuberculous meningitis (NTM) are discussed in this review and aid in accurate diagnosis...
February 29, 2024: Diseases (Basel)
https://read.qxmd.com/read/38534967/amino-acid-metabolism-in-leukocytes-showing-in-vitro-igg-memory-from-sars-cov2-infected-patients
#35
REVIEW
Giuseppina Fanelli, Veronica Lelli, Sara Rinalducci, Anna Maria Timperio
The immune response to infectious diseases is directly influenced by metabolic activities. COVID-19 is a disease that affects the entire body and can significantly impact cellular metabolism. Recent studies have focused their analysis on the potential connections between post-infection stages of SARS-CoV2 and different metabolic pathways. The spike S1 antigen was found to have in vitro IgG antibody memory for PBMCs when obtaining PBMC cultures 60-90 days post infection, and a significant increase in S-adenosyl homocysteine, sarcosine, and arginine was detected by mass spectrometric analysis...
February 23, 2024: Diseases (Basel)
https://read.qxmd.com/read/38534962/the-increase-in-household-transmission-of-pertussis-associated-with-diagnostic-delays
#36
JOURNAL ARTICLE
Alan T Arakkal, Joseph E Cavanaugh, Philip M Polgreen, Aaron C Miller
BACKGROUND: Pertussis is a highly contagious respiratory illness that can be especially dangerous to young children. Transmission of pertussis often occurs in household settings and is impacted by the timing of treatment and postexposure chemoprophylaxis. This study analyzes the risk for secondary household transmission and if delays in diagnosing pertussis increased the risk for household transmission. METHODS: We conducted 2 population-based studies using a large nationally representative administrative claims database...
March 25, 2024: Pediatric Infectious Disease Journal
https://read.qxmd.com/read/38534913/association-of-previous-antibiotics-use-and-kawasaki-disease-a-cohort-study-of-106-908-patients
#37
JOURNAL ARTICLE
Tae-Hwan Kim, Ji Seong Shin, Sin Young Kim, Jihye Kim
BACKGROUND: Microbial imbalance in the gut from antibiotic use may be an etiologic factor of Kawasaki disease (KD). We aimed to identify the association between the use of antibiotics and the development of KD, considering various antibiotic profiles. METHODS: A population-based, case-control study was performed using data from the Health Insurance Review and Assessment Service database. Children <5 years of age, who were diagnosed with KD between 2016 and 2019, were identified...
March 25, 2024: Pediatric Infectious Disease Journal
https://read.qxmd.com/read/38534889/mycobacterium-avium-causing-small-bowel-obstruction-in-an-infant
#38
JOURNAL ARTICLE
Michael A Conti, Michael P Watcher, Kate R Gelman, Martin E Weisse, Federico G Seifarth
No abstract text is available yet for this article.
March 25, 2024: Pediatric Infectious Disease Journal
https://read.qxmd.com/read/38534888/the-impact-of-the-covid-19-pandemic-on-biliary-atresia-incidence-in-a-tertiary-referral-center-in-israel
#39
JOURNAL ARTICLE
Raouf Nassar, Yael Mozer-Glassberg, Michal Rosenfeld Bar-Lev, Raanan Shamir, Michael Gurevich, Orith Waisbourd-Zinman
No abstract text is available yet for this article.
March 25, 2024: Pediatric Infectious Disease Journal
https://read.qxmd.com/read/38534883/uncommon-presentation-of-sarcoidosis-with-severe-thrombocytopenia-and-hemorrhagic-diathesis
#40
Dorela Lame, Michelangelo Pianelli, Shahram Kordasti, Erika Morsia, Attilio Olivieri, Antonella Poloni
Sarcoidosis, a multi-organ system disease, often presents insidiously. Thrombocytopenia in sarcoidosis is frequent because of hypersplenism, granulomas infiltrating the bone marrow, or immune thrombocytopenia (ITP). The diagnosis of ITP relies on exclusionary criteria, given the absence of a definitive laboratory diagnostic feature. In the era prior to modern ITP management, sarcoidosis-associated ITP was known to manifest severely, often showing resistance to treatment and an increased risk of mortality. In this case, we present a young male who was admitted to a district hospital's emergency room, displaying symptoms of hematuria, gingival bleeding, and a petechial rash...
March 4, 2024: Hematology Reports
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