keyword
https://read.qxmd.com/read/38536470/a-multicentre-survey-on-the-perception-of-palliative-care-among-health-professionals-working-in-haematology
#1
JOURNAL ARTICLE
Sara Di Lorenzo, Lisa Mozzi, Flavia Salmaso, Claudia Silvagni, Silvia Soffientini, Vanessa Valenti, Vittorina Zagonel
PURPOSE: Patients with haematologic malignancies have less access to palliative care and are referred later than patients with solid tumours. We developed a survey to investigate this phenomenon, with the intention of analysing palliative care perceptions among health professionals who treat haematology patients and identifying barriers and facilitators to referrals to palliative care services. METHODS: This was a multicentre exploratory descriptive web-based survey...
March 27, 2024: Supportive Care in Cancer
https://read.qxmd.com/read/38532595/guideline-for-laboratory-diagnosis-and-monitoring-of-von-willebrand-disease-a-joint-guideline-from-the-united-kingdom-haemophilia-centre-doctors-organisation-and-the-british-society-for-haematology
#2
JOURNAL ARTICLE
Sean Platton, Peter Baker, Annette Bowyer, Catriona Keenan, Caroline Lawrence, Will Lester, Anne Riddell, Megan Sutherland
No abstract text is available yet for this article.
March 26, 2024: British Journal of Haematology
https://read.qxmd.com/read/38532575/long-term-outcome-of-peripheral-t-cell-lymphomas-ten-year-follow-up-of-the-international-prospective-t-cell-project
#3
JOURNAL ARTICLE
M Civallero, J G Schroers-Martin, S Horwitz, M Manni, Y Stepanishyna, M E Cabrera, J Vose, M Spina, F Hitz, A Nagler, S Montoto, C Chiattone, T Skrypets, M A Perez Saenz, G Priolo, S Luminari, A Lymboussaki, A Pavlovsky, D Marino, M Liberati, J Trotman, D Mannina, M Federico, R Advani
Peripheral T-cell lymphomas (PTCLs) are a heterogeneous group of haematological cancers with generally poor clinical outcomes. However, a subset of patients experience durable disease control, and little is known regarding long-term outcomes. The International T-cell Lymphoma Project (ITCLP) is the largest prospectively collected cohort of patients with PTCLs, providing insight into clinical outcomes at academic medical centres globally. We performed a long-term outcome analysis on patients from the ITCLP with available 10-year follow-up data (n = 735)...
March 26, 2024: British Journal of Haematology
https://read.qxmd.com/read/38532527/management-of-vaccinations-in-patients-with-non-hodgkin-lymphoma
#4
REVIEW
Michele Merli, Andrea Costantini, Silvio Tafuri, Davide Fiore Bavaro, Carla Minoia, Erika Meli, Stefano Luminari, Guido Gini
Vaccinations are fundamental tools in preventing infectious diseases, especially in immunocompromised patients like those affected by non-Hodgkin lymphomas (NHLs). The COVID-19 pandemic made clinicians increasingly aware of the importance of vaccinations in preventing potential life-threatening SARS-CoV-2-related complications in NHL patients. However, several studies have confirmed a significant reduction in vaccine-induced immune responses after anti-CD20 monoclonal antibody treatment, thus underscoring the need for refined immunization strategies in NHL patients...
March 26, 2024: British Journal of Haematology
https://read.qxmd.com/read/38531559/first-intrauterine-transfusion-in-rh-isoimmunised-triplet-pregnancy
#5
JOURNAL ARTICLE
Vandana Bansal, Akshaykumar Babanrao Gangurde, Amol Pawar, Forum Shah
G3P2L1, 28+4 weeks of gestation rhesus (Rh) isoimmunised pregnant women, was referred with trichorionic triamniotic triplet pregnancy with Rh antibody titres of 1:32. Nuchal translucency and anomaly scan were within normal limits with no major malformation for any of the fetuses. Obstetric colour Doppler with middle cerebral artery peak systolic volume revealed foetal anaemia in all three fetuses having velocities corresponding to around 1.5 times the median. Decision of intrauterine transfusion of blood to all three fetuses was taken...
March 25, 2024: BMJ Case Reports
https://read.qxmd.com/read/38529802/correction-to-cytidine-deaminase-status-as-a-marker-of-response-to-azacytidine-treatment-in-mds-and-aml-patients
#6
(no author information available yet)
No abstract text is available yet for this article.
March 26, 2024: British Journal of Haematology
https://read.qxmd.com/read/38528751/a-case-of-philadelphia-chromosome-positive-acute-lymphoblastic-leukemia-with-coexistence-of-jak2-v617f-clone
#7
JOURNAL ARTICLE
Li-Li Han, Haiping Dai, Xia Yang, Junfeng Zhu
No abstract text is available yet for this article.
March 26, 2024: Turkish Journal of Haematology: Official Journal of Turkish Society of Haematology
https://read.qxmd.com/read/38528621/haematoidin-in-chronic-myelomonocytic-leukaemia-during-irregular-treatment-with-hydroxycarbamide
#8
JOURNAL ARTICLE
Xiaohui Zhang, Chaoxin Tao, Fang Long
No abstract text is available yet for this article.
March 25, 2024: British Journal of Haematology
https://read.qxmd.com/read/38527954/pneumocystis-jirovecii-pneumonia-in-paediatric-acute-lymphoblastic-leukaemia-a-report-from-the-multi-international-clinical-trial-aieop-bfm-all-2009
#9
JOURNAL ARTICLE
Anke Barnbrock, Anja Möricke, Draga Barbaric, Neil Jones, Christa Koenig, Reinhard Moser, Marius Rohde, Christina Salvador, Julia Alten, Sarah Elitzur, Andreas H Groll, Thomas Lehrnbecher
Pneumocystis jirovecii can cause life-threatening pneumonia (PjP), and patients with haematological malignancies are at high risk of this infection. Prophylactic measures have significantly decreased morbidity and mortality, but there is a paucity of contemporary data on the incidence and clinical course of PjP in well-defined and homogenous patient populations, such as children suffering from acute lymphoblastic leukaemia (ALL). In the multi-international trial AIEOP-BFM ALL2009, PjP was diagnosed in six children (incidence 1/1000) and was associated with insufficient prophylaxis in five of them...
March 25, 2024: British Journal of Haematology
https://read.qxmd.com/read/38525666/guidance-for-the-gastrointestinal-evaluation-and-management-of-iron-deficiency-in-sub-saharan-africa
#10
REVIEW
W M Simmonds, Y Awuku, C Barrett, M Brand, K Davidson, D Epstein, E Fredericks, S Gabriel, S Grobler, C Gounden, L Katsidzira, V J Louw, V Naidoo, C Noel, E Ogutu, N Ramonate, N Seabi, M Setshedi, J Van Zyl, G Watermeyer, C Kassianides
BACKGROUND: Over 30% of the world's population is anaemic, with a significant proportion of these being iron deficient. As iron deficiency (ID) anaemia in men and post-menopausal women is mostly caused by gastrointestinal blood loss or malabsorption, the initial evaluation of a patient with ID anaemia involves referral to a gastroenterologist. The current drive towards patient blood management in sub-Saharan Africa (SSA)prescribes that we regulate not only the use of blood transfusion but also the management of patients in whom the cause of iron loss or inadequate iron absorption is sought...
February 2, 2024: South African Medical Journal
https://read.qxmd.com/read/38524403/challenges-and-outcomes-of-the-first-stem-cell-transplant-program-in-tanzania-east-africa
#11
JOURNAL ARTICLE
Stella Rwezaula, Mbonea Yonazi, Amey Panchal, Ashish Dhoot, Jemy Mathew, Sonu Tony, Sandeep Rao, Peter Muhoka, Samira Mahfudh, Neema Budodi, Mabula Kasubi, Flora Ndobho, Helena Kakumbula, Koga Luhulla, Linda Kapesa, Heri Tungaraza, Sarah Nyagabona, Agnes Shayo, Felister Seleki, Janeth Mtenga, Khadija Mwamtemi, Musa Suko, Isaac Mbughi, Mariana Shirima, Alfayo Mkisi, Rahma Ally, Malselina Kyaruzi, Else Arola Myaka, Johari Matiku, Mariam Nyamwaira, Saranya Nair, Aswathy Asokan, Goutham Kumar, Raj Badavath, Hedwiga Swai, Lawrence Museru, B S Ajaikumar, Deogratius Beda, Sachin Jadhav
INTRODUCTION: Due to the significant resources involved in creating HSCT programs there is a significant disparity in the availability of this treatment modality between the developed and developing countries. This manuscript details the process and the outcomes of the first HSCT program in East Africa which was started at Muhimbili National Hospital (MNH) in Dar-es-Salaam, Tanzania. MATERIALS AND METHODS: Information and data were collected on the processes which had been implemented for starting the HSCT program at MNH...
2024: Advances in Hematology
https://read.qxmd.com/read/38523360/evaluation-of-new-haematology-analyser-xn-31-for-malaria-detection-in-blood-donors-a-single-centre-study-from-india
#12
JOURNAL ARTICLE
Aseem Kumar Tiwari, Shalini Goel, Ganesh Singh, Pawan Kumar Gahlot, Renu Saxena, Vaibhav Jadhav, Monisha Sethi
BACKGROUND AND OBJECTIVES: Malaria continues to be a significant public health concern in India, with several regions experiencing endemicity and sporadic outbreaks. The prevalence of malaria in blood donors, in India, varies between 0.02% and 0.07%. Common techniques to screen for malaria, in blood donors and patients, include microscopic smear examination and rapid diagnostic tests (RDTs) based on antigen detection. The aim of this study was to evaluate a new fully automated analyser, XN-31, for malaria detection, as compared with current practice of using RDT...
March 24, 2024: Vox Sanguinis
https://read.qxmd.com/read/38522849/natural-history-of-clonal-haematopoiesis-seen-in-real-world-haematology-settings
#13
JOURNAL ARTICLE
Shyam A Patel, William K Gerber, Rena Zheng, Shrinkhala Khanna, Lloyd Hutchinson, Gregory A Abel, Jan Cerny, Brandon A DaSilva, Tian Y Zhang, Muthalagu Ramanathan, Salwa Khedr, William Selove, Bruce Woda, Patricia M Miron, Anne W Higgins, Jonathan M Gerber
Recursive partitioning of healthy consortia led to the development of the Clonal Hematopoiesis Risk Score (CHRS) for clonal haematopoiesis (CH); however, in the practical setting, most cases of CH are diagnosed after patients present with cytopenias or related symptoms. To address this real-world population, we characterize the clinical trajectories of 94 patients with CH and distinguish CH harbouring canonical DNMT3A/TET2/ASXL1 mutations alone ('sole DTA') versus all other groups ('non-sole DTA'). TET2, rather than DNMT3A, was the most prevalent mutation in the real-world setting...
March 24, 2024: British Journal of Haematology
https://read.qxmd.com/read/38522847/comparison-of-platelet-transfusion-effectiveness-between-helicobacter-pylori-positive-and-negative-immune-thrombocytopenia
#14
JOURNAL ARTICLE
Shotaro Tabata, Hiroki Hosoi, Ke Wan, Ayaka Sakaki, Toshiki Mushino, Shogo Murata, Yoshiaki Tomiyama, Takashi Sonoki
Immune thrombocytopenia (ITP) is characterized by early platelet destruction and impaired platelet production. Helicobacter pylori (H. pylori) infection seems to contribute to the pathogenesis in certain ITP patients in Japan. We compared the effectiveness of platelet transfusion in severe ITP in the presence or absence of H. pylori. The median corrected count increment (CCI) at 24 h after platelet transfusion (CCI-24) of the H. pylori-positive ITP patients was higher than that of the H. pylori-negative ITP patients (6463 vs...
March 24, 2024: British Journal of Haematology
https://read.qxmd.com/read/38521530/association-between-immune-inflammatory-indexes-and-lower-urinary-tract-symptoms-an-analysis-of-cross-sectional-data-from-the-us-national-health-and-nutrition-examination-survey-2005-2008
#15
JOURNAL ARTICLE
Wen Liu, Jia Wang, Miaomiao Wang, Xin Ding, Miao Wang, Ming Liu
OBJECTIVE: This study aimed to systematically investigate the relationship between immune-inflammatory indexes with lower urinary tract symptoms (LUTSs). DESIGN: Cross-sectional study. SETTING: National Health and Nutrition Examination Survey (NHANES) (2005-2008). PARTICIPANTS: A total of 2709 men with complete information for immune-inflammatory indexes and LUTSs were included from NHANES 2005-2008. OUTCOMES AND ANALYSES: Automated haematology analysing devices are used to measure blood cell counts, and LUTSs were presented by standard questionnaires...
March 23, 2024: BMJ Open
https://read.qxmd.com/read/38520500/observational-longitudinal-study-on-toxoplasma-gondii-infection-in-fattening-beef-cattle-serology-and-associated-haematological-findings
#16
JOURNAL ARTICLE
Filippo M Dini, Joana G P Jacinto, Damiano Cavallini, Andrea Beltrame, Flavia S Del Re, Laura Abram, Arcangelo Gentile, Roberta Galuppi
Toxoplasmosis, caused by the protozoan parasite Toxoplasma gondii, is a globally distributed zoonotic infection with significant implications for human and animal health. This study investigated the prevalence of T. gondii infection in a population of beef cattle at three different stages of their productive lifespan and examined the impact of T. gondii serological status on blood parameters. A commercial beef fattening unit in Italy was the setting for this research, which involved a biosecurity assessment upon cattle arrival, blood sampling at three time points and Toxoplasma-specific serological testing using indirect fluorescent antibody tests (IFAT)...
March 23, 2024: Parasitology Research
https://read.qxmd.com/read/38517351/a-british-society-for-haematology-guideline-on-the-assessment-and-management-of-bleeding-risk-prior-to-invasive-procedures
#17
JOURNAL ARTICLE
Will Lester, Clare Bent, Raza Alikhan, Laura Roberts, Tim Gordon-Walker, Sarah Trenfield, Richard White, Colm Forde, Deepa J Arachchillage
No abstract text is available yet for this article.
March 22, 2024: British Journal of Haematology
https://read.qxmd.com/read/38514800/the-comparative-study-of-chronically-ill-and-healthy-children-and-adolescents-in-the-light-of-their-general-mental-health
#18
JOURNAL ARTICLE
Péter Boris, Karolina Eszter Kovács, Beáta Erika Nagy
Children's hospitalisation is difficult for the family and the immediate environment. In these cases, the provision of psychological support is particularly important. Chronically ill children who are regularly hospitalised are in a particularly difficult situation, often feeling vulnerable. Our research aims to explore and analyse in detail the psychological state, attitudes and mental health of chronically ill children and to compare patient groups (children receiving care in pulmonology, gastroenterology, onco-haematology and rehabilitation) to understand the interacting factors, which may be of great importance for quality patient care and for measures to improve patient care in the future...
March 21, 2024: Scientific Reports
https://read.qxmd.com/read/38513635/proteomics-landscape-and-machine-learning-prediction-of-long-term-response-to-splenectomy-in-primary-immune-thrombocytopenia
#19
JOURNAL ARTICLE
Ting Sun, Jia Chen, Yuan Xu, Yang Li, Xiaofan Liu, Huiyuan Li, Rongfeng Fu, Wei Liu, Feng Xue, Mankai Ju, Huan Dong, Wentian Wang, Ying Chi, Renchi Yang, Yunfei Chen, Lei Zhang
This study aimed to identify key proteomic analytes correlated with response to splenectomy in primary immune thrombocytopenia (ITP). Thirty-four patients were retrospectively collected in the training cohort and 26 were prospectively enrolled as validation cohort. Bone marrow biopsy samples of all participants were collected prior to the splenectomy. A total of 12 modules of proteins were identified by weighted gene co-expression network analysis (WGCNA) method in the developed cohort. The tan module positively correlated with megakaryocyte counts before splenectomy (r = 0...
March 21, 2024: British Journal of Haematology
https://read.qxmd.com/read/38513454/disrupted-biographies-and-gendered-identities-a-qualitative-study-exploring-sexuality-and-blood-cancer
#20
JOURNAL ARTICLE
Natalie Hammond, Andrew Chantry, Matthew Cheeseman, Alex Peng
PURPOSE: This study examines how blood cancer impacts patients' sexuality and sense of gendered identity. METHODS: An interpretive epistemological framework necessitated a qualitative study design. Participants (6 male and 6 female), recruited from a hospital Haematology department in a large Northern English City, took part in semi-structured in-depth interviews to gather rich data about their subjective experiences. RESULTS: A key theme from the qualitative data was a sense of disruption in relation to several aspects of their gendered identities and sexual life...
February 27, 2024: European Journal of Oncology Nursing: the Official Journal of European Oncology Nursing Society
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