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Seung-Seop Yeom, In Ja Park, Dong-Hoon Yang, Jong Lyul Lee, Yong Sik Yoon, Chan Wook Kim, Seok-Byung Lim, Sung Ho Park, Hwa Jung Kim, Chang Sik Yu, Jin Cheon Kim
PURPOSE: Although the height of a rectal tumor above the anal verge (tumor height) partly determines the treatment strategy, no practical standard exists for reporting this. We aimed to demonstrate the differences in tumor height according to the diagnostic modality used for its measurement. METHODS: We identified 100 patients with rectal cancers located within 15 cm of the anal verge who had recorded tumor heights measured by using magnetic resonance imaging (MRI), colonoscopy, and digital rectal examination (DRE)...
February 2019: Annals of Coloproctology
Kwan Mo Yang, In Ja Park, Jong Lyul Lee, Yong Sik Yoon, Chan Wook Kim, Seok-Byung Lim, Na Young Kim, Shinae Hong, Chang Sik Yu, Jin Cheon Kim
PURPOSE: We evaluate the prognostic value of primary tumor location for oncologic outcomes in patients with colon cancer (CC). METHODS: CC patients treated with curative surgery between 2009 and 2012 were classified into 2 groups: right-sided colon cancer (RCC) and left-sided colon cancer (LCC). Recurrence-free survival (RFS) and overall survival (OS) were examined based on tumor stage. Propensity scores were created using eight variables (age, sex, T stage, N stage, histologic grade, presence of lymphovascular invasion/perineural invasion, and microsatellite instability status)...
February 2019: Annals of Coloproctology
Bowen Wang, Bingfen Huang, Junmei Chen, Wenpeng Li, Ling Yang, Lunguang Yao, Qiuhong Niu
Colonization resistance is an important attribute for bacterial interactions with hosts, but the mechanism is still not completely clear. In this study, we found that Phytobacter sp. SCO41T can effectively inhibit the in vivo colonization of Bacillus nematocida B16 in Caenorhabditis elegans, and we revealed the colonization resistance mechanism. Three strains of colonization-resistant bacteria, SCO41T , BX15, and BC7, were isolated from the intestines of the free-living nematode C. elegans derived from rotten fruit and soil...
March 16, 2019: Molecular Biology Reports
Qiong Yang, Zhiyong Wu, Xujun He, Leibo Yu, Xiaofei Zhang, Kefeng Lei
INTRODUCTION: To explore the effect of a second thyroid cancer (TC) on ovarian cancer (OC) patient survival, we compared OC patients with or without a second primary TC using data from the Surveillance, Epidemiology, and End Results (SEER) database. METHODS: Data for OC only, female TC only and OC patients with a second TC (OC2TC) from two periods, 2000-2014 and 1980-1994, were extracted from the SEER database. Differences in clinicopathological and treatment characteristics were analysed using the chi-square test...
March 16, 2019: Advances in Therapy
Yanyan Fang, Zhiqiang Nie, Jinzhong Yang, Qingqi Die, Jie He, Hongjin Yu, Qi Zhou, Qifei Huang
Secondary aluminum smelting industry, as an important source of polychlorinated naphthalene (PCN) in environment, has been concerned in recent years. To figure out the emission characteristics of PCNs and the potential influence on surrounding environment, two typical secondary aluminum smelting plants were selected and PCNs were determined in flue gas, fly ash, aluminum slag, soil, and air samples collected at and around the plants by GC-MS coupled with DFS. PCN emission factors from the flue gas of the two plants (mean 0...
March 16, 2019: Environmental Science and Pollution Research International
Yanying Wang, Yan Yang, Wei Liu, Fang Ding, Ping Zou, Xianxiang Wang, Qingbiao Zhao, Hanbing Rao
A dual-mode method was developed for the determination of ascorbic acid (AA) and of ascorbic acid oxidase (AA-Ox) activity. It combines the advantages of ratiometric fluorometry and colorimetry. The assay is based on the oxidation of o-phenylenediamine (OPDA) by permanganate (KMnO4 ). A yellow substance (referred to as oxOPDA) with an absorption peak at 425 nm is rapidly produced in the presence of the oxidant. oxOPDA reduces the blue fluorescence of carbon dots (C-dots) peaking at 450 nm (upon 380-nm excitation), and a new emission peak is found at 565 nm...
March 16, 2019: Mikrochimica Acta
J-W Feng, X-H Yang, B-Q Wu, D-L Sun, Y Jiang, Z Qu
BACKGROUND: Central lymph node metastasis (LNM) in papillary thyroid carcinoma (PTC) is common. But the association between primary tumor characteristics and specific features of metastatic lymph nodes in PTC has not been fully identified. Determining risk factors for LNM may help surgeons determine rational extent of lymph node dissection. METHODS: Data from 432 patients who underwent thyroidectomy with cervical lymph node dissection for PTC were retrospectively analyzed...
March 16, 2019: Clinical & Translational Oncology
Xinnan Liu, Wentao Zhang, Chengyuan Yang, Yuan Yao, Lunjie Huang, Sihang Li, Jianlong Wang, Yanwei Ji
The authors describe a fluorometric method for the quantification of tannic acid (TA). MoO3-x quantum dots (QDs) can selectively capture TA via the formation of an organic molybdate complex. This causes an electron transfer effect and an inner filter effect to result in synergistic quenching of the fluorescence of the QDs. TA can be detected via this effect with a linear response in the of 0.1-10 μM concentration range and a lower detection limit of 30 nM within 1 min. The use of such QDs as a quenchable fluorescent probe warrants good selectivity even in the presence of relatively high concentration of potentially interferents and makes the method suitable for real sample analysis...
March 16, 2019: Mikrochimica Acta
Jason C Hsu, Chen-Fang Wei, Szu-Chun Yang
INTERVENTIONS: Targeted therapies have been proven to provide clinical benefits to patients with metastatic non-small cell lung cancer (NSCLC). Gefitinib was initially approved and reimbursed as a third-line therapy for patients with advanced NSCLC by the Taiwan National Health Insurance (NHI) in 2004; subsequently it became a second-line therapy (in 2007) and further a first-line therapy (in 2011) for patients with epidermal growth factor receptor mutation-positive advanced NSCLC. Another targeted therapy, erlotinib, was initially approved as a third-line therapy in 2007, and it became a second-line therapy in 2008...
March 15, 2019: BMJ Open
Chao Zhang, Xiaohong Yao, Ying Chen, Qiang Chu, Yang Yu, Jinhui Shi, Huiwang Gao
Dust deposition can bring nutrients and trace elements to the upper ocean and affect phytoplankton growth and community structure. We conducted a comparative study using on-board microcosm experiments amended with varying amounts of dust (0.2, 1, and 2 mg L-1 ) in the East China Sea (eutrophic zone), the subtropical gyre (low-nutrient and low-chlorophyll zone, LNLC), and the Kuroshio-Oyashio transition region (high-nutrient and low-chlorophyll zone, HNLC) of the Northwest Pacific Ocean. The additions of dust supplied a considerable amount of nitrogen (N) and negligible phosphorus (P) relative to the seawater collected for incubation experiments (baseline), contributing to increases in Chlorophyll a with increasing dust additions...
February 28, 2019: Science of the Total Environment
Zefeng Song, Xinyao Yang, Fangmin Chen, Fangyuan Zhao, Ying Zhao, Lili Ruan, Yinggang Wang, Yuesuo Yang
Environmental processes of nanoplastics in heterogeneous natural groundwater systems remain unclear. In this study, the control of particle size and surface functional groups on the fate and transport of nanoplastics in an organic matter (OM) rich aquifer was explored using batch and column tests. The carboxyl-modified 200 nm (200CNP), carboxyl-modified 50 nm (50CNP), and amino-modified 50 nm (50ANP) polystyrene latex beads were used as surrogates for nanoplastics of contrasting sizes and surface functional groups...
March 8, 2019: Science of the Total Environment
Hongyang Wu, Wenjuan Wang, Yanfang Huang, Guihong Han, Shuzhen Yang, Shengpeng Su, Hafiza Sana, Weijun Peng, Yijun Cao, Jiongtian Liu
Toxic metal pollutants threaten water environment. It exists undesirably metal-ion concentration limits with conventional precipitation flotation. An enhanced precipitation flotation system focusing on efficient removal for bivalent metal-ions was researched. The system involved the addition of humics and Fe3+ to generate and regulate the precipitates. The characteristics of precipitates were investigated by particle analysis, conditional stability constants and DLVO theory calculations, and SEM&TEM imaging...
March 12, 2019: Journal of Hazardous Materials
Yi-Ping Chen, Li-Ming Yang, J Paul Chen, Yu-Ming Zheng
In this study, a highly active electro-Fenton catalyst, spongy zero-valent iron (ZVI), has been developed at first via in-situ synthesis of ZVI nanoparticles (NPs) on an electrospun three-dimensional (3D) nanofiber network. The spongy ZVI effectively overcame the defects of easy aggregation of ZVI NPs and ferric sludge accumulation during the electro-catalytic process. Then, a three-dimensional electro-Fenton (3D-EF) system using the as-fabricated spongy ZVI as particle catalytic electrodes was designed, which presented a significant synergistic effect of adsorption and electro-catalytic oxidation on the enhanced removal of a widely used antibiotic, sulfathiazole (STZ) from water...
March 11, 2019: Journal of Hazardous Materials
Liwei Chen, Shengjiong Yang, Yang Huang, Baogang Zhang, Fuxing Kang, Dahu Ding, Tianming Cai
Abatement of antibiotics from aquatic systems is of great importance but remains a challenge. Herein, we prepared ternary AgBr/Ag3 PO4 @natural hematite (AgBr/Ag3 PO4 @NH) heterojunction composite via a simple route for the photocatalytic degradation of antibiotic pollutants. By adjusting the dose of Ag species, four products with different Ag content (denoted as Ag0.5 BrPFe, Ag1 BrPFe, Ag1.5 BrPFe, and Ag2 BrPFe) were developed. Among them, Ag1.5 BrPFe exhibited the best photocatalytic activity. Four antibiotics (i...
March 8, 2019: Journal of Hazardous Materials
Wei Li, Yi Wu, Mali Wan, Yang Chu, Xiangyang Wang, Shuming Li, Zuhui Liu, Xue Chen, Navaneethakrishnan Polachi, Shuiping Zhou, He Sun
As one of the main constituents of Compound Danshen Dripping Pills (CDDP), Panax notoginseng (PN) plays a pivotal role in the treatment of cardiovascular diseases. Numerous researches have proved that the dammarane type saponins including notoginsenoside R1 (NR1), ginsenoside Rg1 (GRg1) and ginsenoside Rb1 (GRb1) are the main bioactive components of PN in CDDP. An efficient, realiable and sensitive liquid chromatography tandem-mass spectrometry (LC-MS/MS) analysis method for simultaneously detecting NR1, GRg1 and GRb1 in human plasma was established and applied to the pharmacokinetics study of the three PN saponins after oral administration of CDDP...
March 5, 2019: Journal of Pharmaceutical and Biomedical Analysis
Xue-Feng Lu, Yang Zhou, Yu-Peng Ren, Jian Zhang
This work reports the development and application of a multi-compound analysis method for the determination of 17 flavonoids and polyphenols in sweet potato leaves. Samples were processed by microwave-enhanced accelerated solvent extraction under low pressure at 120 °C for 10 min. Salting-out homogeneous liquid-liquid extraction was used to remove water and water-soluble impurities from the extract before ultra performance convergence chromatography-tandem mass spectrometry analysis. By using the supercritical fluid (CO2 and methanol) as the mobile phase, the 17 components and the internal standard were well separated in 10 min without obvious matrix effect...
March 4, 2019: Journal of Pharmaceutical and Biomedical Analysis
Fengguo Zhang, Zhe Chen, Shengyi Zhong, Han Chen, Jun Liu, Qing Yang, Haowei Wang
The mechanical behavior of particle-reinforced composites is largely determined by the interaction between the reinforcing particles and matrix. Although conventional digital image correlation (DIC) allows accurate measurements of strain at microscale, it usually requires preparation of synthetic pattern on the sample surface, which would affect the observation of reinforcing particles. An approach is proposed in this work that relies solely on the reinforcing particles as DIC pattern, thereby enabling concurrent microstructure observation and strain measurement...
March 1, 2019: Micron: the International Research and Review Journal for Microscopy
Jiao Cai, Baizhan Li, Wei Yu, Han Wang, Chenqiu Du, Yinping Zhang, Chen Huang, Zhuohui Zhao, Qihong Deng, Xu Yang, Xin Zhang, Hua Qian, Yuexia Sun, Wei Liu, Juan Wang, Qin Yang, Fanbin Zeng, Dan Norbäck, Jan Sundell
During 2010-2012, we conducted an observational study on household environment and health outcomes among 40,010 preschool children from seven cities of China. Here we examined associations of six dampness-related indicators (visible mold spots, visible damp stains, damp clothing and/or bedding, water damage, condensation on windowpane, moldy odor) in the current residence and three dampness-related indicators (visible mold spots, condensation on windowpane, moldy odor) in the early residence with childhood asthma and rhinitis...
March 14, 2019: Environment International
Bo-Yi Yang, Iana Markevych, Michael S Bloom, Joachim Heinrich, Yuming Guo, Lidia Morawska, Shyamali C Dharmage, Luke D Knibbs, Bin Jalaludin, Pasi Jalava, Xiao-Wen Zeng, Li-Wen Hu, Kang-Kang Liu, Guang-Hui Dong
BACKGROUND: Living in greener areas has many health benefits, but evidence concerning the effects on blood pressure remains mixed. We sought to assess associations between community greenness and both blood pressure and hypertension in Chinese urban dwellers, and whether the associations were mediated by air pollution, body mass index, and physical activity. METHODS: We analyzed data from 24,845 adults participating in the 33 Communities Chinese Health Study, which was conducted in Northeastern China during 2009...
March 14, 2019: Environment International
Liyuan Chai, Chunlian Ding, Jiawei Li, Zhihui Yang, Yan Shi
The release of hexavalent chromium [Cr(VI)] into water bodies poses a major threat to the environment and human health. However, studies of the biological response to Cr(VI) are limited. In this study, a toxic bacterial mechanism of Cr(VI) was investigated using Pannonibacter phragmitetus BB (hereafter BB), which was isolated from chromate slag. The maximum Cr(VI) concentrations with respect to the resistance and reduction by BB are 4000 mg L-1 and 2500 mg L-1 , respectively. In the BB genome, more genes responsible for Cr(VI) resistance and reduction are observed compared with other P...
March 6, 2019: Environmental Pollution
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