Huaxin Li, Mengxue Zhang, Yuanyu Wang, Ke Gong, Tengteng Yan, Dandan Wang, Xianshe Meng, Xiaoxiao Yang, Yuanli Chen, Jihong Han, Yajun Duan, Shuang Zhang
Heart failure (HF) is a clinical syndrome characterized by typical symptoms that usually occur at the end stage of various heart diseases and lead to death. Daidzein (DAI), an isoflavone found in soy foods, is widely used to treat menopausal syndrome, prostate cancer, breast cancer, heart disease, cardiovascular disease, and osteoporosis, and has anti-oxidant and anti-inflammatory properties. However, the effects of DAI in HF remain unknown. In this study, doxorubicin (DOX) was used to establish HF models of C57BL/6J mice and H9c2 cells with DAI treatment...
August 24, 2022: Food & Function