keyword
https://read.qxmd.com/read/38527189/demographic-and-clinical-profile-of-pediatric-uveitis-in-delta-region-egypt
#1
JOURNAL ARTICLE
Nagwa Hussein Abdelmageed, Anas Adi, Samy Abo El-Khair, Maha Shahin, Doaa Mosad Mosa, Dalia Sabry, Amgad El Nokrashy
PURPOSE: Pediatric uveitis poses unique challenges, characterized by difficulties in performing comprehensive examinations, potential delays in diagnosis, and a heightened risk of ocular complications. This study evaluate the etiologic and clinical characteristics of uveitis in children presenting to the Mansoura Ophthalmic Center, Mansoura, Egypt. METHODS: A cross-sectional observational study was undertaken involving children diagnosed with uveitis attending the uveitis outpatient clinic at Mansoura University Ophthalmic Center...
March 25, 2024: Ocular Immunology and Inflammation
https://read.qxmd.com/read/38526248/factors-influencing-effects-of-low-dose-radiation-exposure
#2
JOURNAL ARTICLE
Carmel Mothersill, Colin Seymour, Alan Cocchetto, David Williams
It is now well accepted that the mechanisms induced by low-dose exposures to ionizing radiation (LDR) are different from those occurring after high-dose exposures. However, the downstream effects of these mechanisms are unclear as are the quantitative relationships between exposure, effect, harm, and risk. In this paper, we will discuss the mechanisms known to be important with an overall emphasis on how so-called "non-targeted effects" (NTE) communicate and coordinate responses to LDR. Targeted deposition of ionizing radiation energy in cells causing DNA damage is still regarded as the dominant trigger leading to all downstream events whether targeted or non-targeted...
May 1, 2024: Health Physics
https://read.qxmd.com/read/38454850/chandelier-assisted-scleral-buckle-surgery-contact-versus-non-contact-wide-angle-viewing-system-cab-cnv-a-retrospective-multicenter-clinical-study
#3
JOURNAL ARTICLE
Aditya S Kelkar, Manish Nagpal, Sukanya Mondal, Navneet Mehrotra, Harsh Jain, Akansha Sharma, Erwin Camus, Vaidehi Sathaye
PURPOSE: To investigate and compare the anatomic and functional outcomes of chandelier-assisted scleral buckling (CASB) surgery using contact versus non-contact lens-based wide-angle viewing systems (WAVSs) in rhegmatogenous retinal detachment (RRD) patients. METHODS: This was a retrospective, multicenter study evaluating the anatomic (reattachment rate) and visual acuity (VA) outcomes at 6 months post-CASB for primary RRD. RESULTS: Forty-seven RRD patients underwent CASB with a non-contact WAVS (Group C1) and 90 with a contact lens WAVS (Group C2)...
March 8, 2024: Indian Journal of Ophthalmology
https://read.qxmd.com/read/38454840/visual-axis-opacification-after-pediatric-cataract-surgery-an-analysis-of-morphology-and-etiology
#4
JOURNAL ARTICLE
Sudarshan Khokhar, Lekha Chandel, Deeksha Rani, Aishwarya Rathod, Venkatesh Nathiya, Amar Pujari
PURPOSE: To investigate the morphological types and delineate the clinical and surgical variables associated with VAO in children undergoing pediatric cataract surgery. METHODS: We included 33 eyes of 28 children who developed clinically significant visual axis opacification (VAO) after congenital or developmental cataract surgery. All eyes underwent a comprehensive examination under anesthesia followed by a membranectomy to clear the visual axis. We classified VAO into three subgroups: fibrotic, proliferative, and combined morphologies...
March 8, 2024: Indian Journal of Ophthalmology
https://read.qxmd.com/read/38444718/untreated-classic-galactosemia-a-rare-cause-of-adult-onset-progressive-cerebellar-ataxia-a-case-report
#5
Ioannis Karafyllis, Jean-Marc Nuoffer, Joan-Philipp Michelis, Lara Chilver-Stainer
INTRODUCTION: Identifying the underlying etiology of nonfamilial adult-onset progressive cerebellar ataxia is often challenging because neurologists must consider almost all nongenetic and genetic causes of ataxia. CASE PRESENTATION: A 39-year-old woman was hospitalized for progressive ataxia with pyramidal and cognitive dysfunction after a right arm shaking and coordination problem deteriorated progressively over 1.5 years. The patient's medical history included amenorrhea, cataracts, developmental delays, consanguinity of the parents, motor coordination issues, and diarrhea and vomiting in infancy...
2024: Case Reports in Neurology
https://read.qxmd.com/read/38439905/childhood-vision-impairment-and-blindness-in-west-africa-public-health-measures-and-implications-for-systemic-health
#6
REVIEW
Caleb Yeh, Crystal Huang, Ye Huang, Caleb D Hartley, Tolulope Fashina, Nathaniel Ashby, Chase Miller, Jessica G Shantha, Grant A Justin, R V Paul Chan, John G Mattia, Matthew J Vandy, Lloyd Harrison-Williams, Jalikatu Mustapha, Jean-Claude Mwanza, Steven Yeh
Childhood blindness is an issue of global health impact, affecting approximately 2 million children worldwide. Vision 2020 and the United Nations Sustainable Development Goals previously identified childhood blindness as a key issue in the twentieth century, and while public health measures are underway, the precise etiologies and management require ongoing investigation and care, particularly within resource-limited settings such as sub-Saharan Africa. We systematically reviewed the literature on childhood blindness in West Africa to identify the anatomic classification and etiologies, particularly those causes of childhood blindness with systemic health implications...
2024: Frontiers in Medicine
https://read.qxmd.com/read/38433348/the-etiology-diagnostics-and-treatment-of-the-spasm-of-the-near-reflex-a-narrative-review
#7
REVIEW
Michalina Szczęśniak, Ewa Sikorska, Martyna Rajca, Mateusz Koper, Wojciech Kopacz, Piotr Sikorski, Piotr Maciejewicz, Kaja Kasarełło
Physiological adaptation of the eye to the visual perception of near objects consists of the "near triad": convergence, accommodation, and pupil miosis. Normally, these tend to revert when one stops fixating on a near object. Spasm of the near reflex (SNR) is a pathological phenomenon, which manifests itself by the persistence of the above-mentioned adjustments, which prevents the eye from returning to its relaxed state. In this narrative review, we aim to summarize the etiology, diagnostics, treatment, and prevention of SNR...
March 3, 2024: European Journal of Ophthalmology
https://read.qxmd.com/read/38421248/sensory-strabismus-a-literature-review
#8
REVIEW
Masoud Khorrami-Nejad, Alaa Alghurab, Mohamad Reza Akbari, Elham Azizi, Babak Masoomian
Persistent unilateral or bilateral visual deprivation at any age, particularly in children, can compromise sensory fusion and result in a type of strabismus known as sensory or secondary strabismus. There are several pathologies that can induce visual impairment, such as severe anisometropia, congenital unilateral cataract, corneal opacity, retinal diseases, and optic nerve anomalies. Sensory strabismus may be horizontal or vertical or a combination of them; however, most reports indicate the development of horizontal deviation as sensory strabismus...
2024: Journal of Binocular Vision and Ocular Motility
https://read.qxmd.com/read/38386915/successful-treatment-of-clinically-diagnosed-cancer-associated-retinopathy-with-intravitreal-dexamethasone-implant-followed-by-0-18-mg-fluocinolone-implant-without-systemic-immunosuppression
#9
JOURNAL ARTICLE
Lingling Huang, Paul Yang, Christina Flaxel, Eric Suhler, Phoebe Lin
PURPOSE: To report a case of clinically diagnosed cancer-associated retinopathy (CAR) successfully treated with intravitreal corticosteroid implants without systemic immunosuppression. METHODS: Case report with multimodal imaging. RESULTS: An 80-year-old man without known systemic malignancy presented with debilitating shimmering, hemeralopia and rapidly progressive bilateral vision loss following uncomplicated cataract surgery. Mild vitritis, extensive photoreceptor loss, mottling of retinal pigmentary epithelium (RPE), and mild vascular attenuation were found in both eyes...
February 22, 2024: Retinal Cases & Brief Reports
https://read.qxmd.com/read/38385387/ocular-symptoms-in-kidney-liver-and-heart-transplant-patients
#10
JOURNAL ARTICLE
Almila Sarigul Sezenoz, Gulsah Gokgoz, Irem Kirci Dogan, Sirel Gur Gungor, Sibel Oto, Mehmet Haberal
OBJECTIVES: The purpose of this study was to report the ocular manifestations in kidney, liver, and heart transplant recipients. MATERIALS AND METHODS: We reviewed the medical records of kidney, liver, and heart transplant recipients who were examined at the ophthalmology clinic of a tertiary hospital between October 2021 and October 2022. We evaluated the ocular complaints of the patients, ophthalmological examination findings, the etiology of the underlying disease, comorbidities, posttransplant duration, and the medications used...
January 2024: Experimental and Clinical Transplantation
https://read.qxmd.com/read/38372515/clinical-and-therapeutic-characteristics-of-childhood-uveitis-in-a-tertiary-center-in-tunisia
#11
JOURNAL ARTICLE
Salma Gargouri, Kmar Maaloul, Imene Kaibi, Mona Rekik, Hajer Aloulou, Amira Trigui
INTRODUCTION: Childhood uveitis is a rare condition with various associated diagnostic and therapeutic challenges. AIM: We proposed to describe the distribution, clinical findings, treatment, complications, and visual outcomes of uveitis in children at a tertiary referral center in Sfax, Tunisia. METHODS: A retrospective study of 33 children (54 eyes) with uveitis collected over the period from January 2009 to December 2018 was carried out at the Ophthalmology Department of Habib Bourguiba University Hospital, Sfax, Tunisia...
May 5, 2023: La Tunisie Médicale
https://read.qxmd.com/read/38363356/outcomes-of-pars-plana-vitrectomy-in-the-management-and-diagnosis-of-patients-with-infectious-non-infectious-and-unidentified-uveitis
#12
JOURNAL ARTICLE
Hande Celiker, Furkan Çam, Berru Yargı Özkoçak
PURPOSE: To present the outcomes of pars plana vitrectomy (PPV) in patients with infectious, non-infectious, and unidentified uveitis, focusing on visual and clinical outcomes, diagnostic yield, and surgery-related complications. METHODS: This retrospective, single-center study included patients who underwent 23-gauge PPV for the management of uveitis and had at least 6 months of follow-up. Patients were divided into infectious, non-infectious, and unidentified uveitis groups based on definitive diagnosis after surgery...
February 16, 2024: Graefe's Archive for Clinical and Experimental Ophthalmology
https://read.qxmd.com/read/38350160/eyelid-margin-disease-blepharitis-and-meibomian-gland-dysfunction-clinical-review-of-evidence-based-and-emerging-treatments
#13
JOURNAL ARTICLE
Karolinne Maia Rocha, Marjan Farid, Leela Raju, Kenneth Beckman, Brandon D Ayres, Elizabeth Yeu, Naveen Rao, Winston Chamberlain, Zachary Zavodni, Barry Lee, Julie Schallhorn, Sumit Garg, Francis S Mah
Blepharitis is a common ophthalmic condition with multiple etiologies and no definitive, universal treatment. The treatment modalities for managing lid margin diseases vary depending on the disease's cause, location, and severity. For anterior blepharitis, management options include eyelid hygiene with warm compresses, eyelid scrubs, baby shampoo, and over-the-counter eyelid cleansers. Topical antibiotics and antibiotic-steroid combination drops/ointments for the eye and eyelid may accompany these. For posterior blepharitis/meibomian gland dysfunction (MGD), at-home warm compress or in-office administration of heat therapy/thermal pulsation treatment that aims to clear obstruction in the meibomian glands and restore meibum secretions to maintain a healthy tear film, are recommended...
February 6, 2024: Journal of Cataract and Refractive Surgery
https://read.qxmd.com/read/38324301/role-of-serine-protease-inhibitors-a1-and-a3-in-ocular-pathologies
#14
JOURNAL ARTICLE
Richard Kontoh-Twumasi, Stepan Budkin, Neel Edupuganti, Ayushi Vashishtha, Shruti Sharma
Serine protease inhibitors A1 (SerpinA1) and A3 (SerpinA3) are important members of the serpin family, playing crucial roles in the regulation of serine proteases and influencing various physiological processes. SerpinA1, also known as α-1-antitrypsin, is a versatile glycoprotein predominantly synthesized in the liver, with additional production in inflammatory and epithelial cell types. It exhibits multifaceted functions, including immune modulation, complement activation regulation, and inhibition of endothelial cell apoptosis...
February 1, 2024: Investigative Ophthalmology & Visual Science
https://read.qxmd.com/read/38317316/clinical-profile-and-treatment-outcomes-in-pediatric-uveitis-a-series-from-south-india
#15
JOURNAL ARTICLE
Vidya S Mooss, Kalpana Babu
PURPOSE: The purpose of the study was to look at the clinical spectrum, treatment options, and visual outcomes in a large cohort of pediatric uveitis from a tertiary eye care center in South India. METHODS: This is a retrospective study carried out at a tertiary eye center in South India. Cases of pediatric uveitis between January 2012 and June 2022 were retrieved from the hospital's medical database. Uveitis was classified according to the Standardization of Uveitis Nomenclature criteria...
February 5, 2024: Indian Journal of Ophthalmology
https://read.qxmd.com/read/38311572/subnormal-visual-acuity-after-compliant-amblyopia-therapy-residual-refractory-amblyopia-or-co-existing-pathology-a-retrospective-analysis
#16
JOURNAL ARTICLE
Virender Sachdeva, Bidisha Bhattacharya, Snehal Ganatra, Ramesh Kekunnaya
Purpose : To assess the prevalence of alternate etiology/co-existing pathology among patients with amblyopia, and to characterize factors contributing to over-diagnosis of amblyopia. Methods : We retrospectively reviewed records of children (from 1 January 2016 to 31 December 2019) who were initially diagnosed as "amblyopia" but later an alternate diagnosis for subnormal vision was established. Patients who had a best corrected visual acuity (BCVA) of ≤20/32 (0.2 logMAR) after compliant amblyopia therapy were divided into 2 groups: those with refractory amblyopia (BCVA improvement from baseline <1 logMAR line) and residual amblyopia (BCVA improvement from baseline >1 logMAR line)...
February 4, 2024: Strabismus
https://read.qxmd.com/read/38292780/fahr-syndrome-and-neurological-manifestations-in-hypoparathyroidism-patients
#17
Vincentius Diamantino Supit, Dedy Kurniawan, Ersifa Fatimah
Fahr syndrome is an uncommon (prevalence < 1/1.000.000) neurological disorder characterized by abnormal calcified deposits in the basal ganglia, nucleus dentatus, and cerebral cortex. These calcification can lead to various neurological manifestations. Distinguishing Fahr syndrome from Fahr disease is crucial due to differences in their etiology, location of lesions, prognosis, and therapy. Currently, Fahr disease lacks a specific treatment, while Fahr syndrome requires target intervention based on the underlying cause...
April 2024: Radiology Case Reports
https://read.qxmd.com/read/38271417/long-term-outcomes-of-iris-sutured-subluxated-intraocular-lenses
#18
JOURNAL ARTICLE
Taylor Nayman, Daniel Milad, Mikael Sebag
PURPOSE: This study evaluated the long-term outcomes of managing posterior chamber intra-ocular lens (IOL) (PCIOL) subluxation through pars plana vitrectomy (PPV) with IOL iris suturing. SETTINGS AND DESIGN: Retrospective chart review. METHODS: Patients who underwent PPV with iris-sutured IOL (IS-IOL) for IOL subluxation between January 2008 and April 2021 at a tertiary center with a minimum of 6 months of follow-up were included. The patients were divided into two groups: those who had prior PPV and those who had not undergone the procedure...
February 1, 2024: Indian Journal of Ophthalmology
https://read.qxmd.com/read/38251992/clinical-and-histopathologic-ocular-findings-in-aquarium-housed-cownose-rays-rhinoptera-bonasus
#19
JOURNAL ARTICLE
Braidee C Foote, Lindsay D Seyer, Laura Martinelli, Caroline Betbeze, Kim Newkirk, Karen Terio, Xiaojuan Zhu, James G Johnson, Jared Durrett, Chris Buckner, Christa E Barrett, Julie D Sheldon
Cownose rays ( Rhinoptera bonasus ) are susceptible to ocular disease with their prominent globes, but despite being popular animals housed in aquaria, there is little published information about their normal ocular anatomy and common pathologic ocular findings. A total of 63 live cownose rays (CNR) from three unrelated, separately housed groups had ocular examinations, and 5 adult rays were selected for ocular ultrasound. All examinations were performed out of the water, and most without anesthesia. Clinical findings were described, categorized, and scored by severity...
January 2024: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
https://read.qxmd.com/read/38216115/identification-of-pathogenic-genetic-variants-in-patients-with-acquired-early-onset-bilateral-cataracts-using-next-generation-sequencing
#20
JOURNAL ARTICLE
Jamie C Fox, Rana Dutta, Bharti R Nihalani, Amy Ponte, Dana M Talsness, Deborah K VanderVeen, Robert D Steiner, Sharon F Freedman
BACKGROUND: Acquired early-onset bilateral cataracts can result from systemic etiologies or genetic disorders. METHODS: In this observational study, we analyzed individuals 18 months to 35 years of age with acquired bilateral cataracts via a next-generation sequencing panel of 66 genes to identify disease-causing genetic variants. RESULTS: Of 347 patients enrolled, 313 (90.2%) were <19 years (median, 8 years). We identified 74 pathogenic or likely pathogenic variants in 69 patients...
January 10, 2024: Journal of AAPOS: the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
keyword
keyword
169278
1
2
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.