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Lemu Golassa, James Cheaveau, Abu Naser Mohon, Dylan R Pillai
No abstract text is available yet for this article.
February 15, 2019: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
Aurash Naser-Tavakolian, Saum Ghodoussipour, Hooman Djaladat
PURPOSE OF REVIEW: Our aim is to review recent investigations into the recurrence of urothelial carcinoma in the upper urinary tract following bladder cancer therapy focusing on surveillance and management. RECENT FINDINGS: After radical cystectomy, rates of recurrence in the upper tract are between 0.75 and 6.4%. The poor prognosis of upper tract urothelial carcinoma (UTUC) is in part attributable to delayed diagnosis. Guidelines recommend a gradual de-escalation of surveillance in disease-free patients with the potential for discontinuation beyond 5 years...
February 11, 2019: Current Opinion in Urology
Naser Gholizadeh-Moghadam, Bahman Hosseini, Abolfazl Alirezalu
INTRODUCTION: Recently, there has been a growing interest in the use of edible barberry and their extracts as a source of natural antioxidants in food and pharmaceutical industries. OBJECTIVE: The aim of this study was to evaluate the biochemical constituents of 18 samples of barberry fruits and classification of barberry genotypes by multivariate analysis. METHODS: Total phenolic, total flavonoid, total anthocyanin, total tannin, total carbohydrate contents and antioxidant activity were determined using Folin-Ciocalteu, aluminum chloride, colorimetric, vanillin, anthron and DPPH (2,2'-diphenyl-1-picrylhydrazyl) assays, respectively...
February 14, 2019: Phytochemical Analysis: PCA
Mahnaz Heidari, Sara Darbandi, Mahsa Darbani, Naser Amirjanati, Mahmood Bozorgmehr, Hojjat Zeraati, Mohammad Mehdi Akhondi, Mohammad Reza Sadeghi
Background: The selection of sperm with good genomic integrity and surface antigens is suggested for improving assisted reproductive technology (ART) outcome. The aim of this study was evaluating the heat shock protein (HSPA2), Dj-1 and serum amyloid P compound (SAP) three sperm surface proteomes as biomarkers for this purpose. Methods: In this study, semen samples were obtained from 114 men who presented at Avicenna Fertility Clinic for their treatment. The semen characteristics, DNA fragmentation Index (DFI), chromatin maturation index (CMI), biomarker levels, and their embryo quality were considered...
October 2018: Journal of Reproduction & Infertility
Elham Afjeh-Dana, Parvneh Naserzadeh, Hojatollah Nazari, Fatemeh Motaghitalab, Ronak Shabani, Naser Aminii, Bita Mehravi, Fatemeh Tajik Rostami, Mohammad Taghi Joghataei, Kazem Mousavizadeh, Khadijeh Ashtari
Nowadays, regenerating peripheral nerves injuries (PNIs) remain a major clinical challenges, which has gained a great attention between scientists. Here, we represent a nanocomposite based on silk fibroin reinforced gold nanorods (SF/GNRs) to evaluate the proliferation and attachment of PC12 cells. The morphological characterization of nanocomposites with transmission electron microscopy (TEM) and Scanning electron microscopy (SEM) showed that the fabricated scaffolds have porous structure with interconnected pores that is suitable for cell adhesion and growth...
February 8, 2019: International Journal of Biological Macromolecules
Shahnawaz Imam, R Prathibha, Pervaiz Dar, Khalil Almotah, Ahmed Al-Khudhair, Syed Abdul-Moiz Hasan, Nancy Salim, Talha Naser Jilani, Raghavendra G Mirmira, Juan Carlos Jaume
We have developed a transgenic mouse model of Type 1 Diabetes (T1D) in which human GAD65 is expressed in pancreatic β-cells, and human MHC-II is expressed on antigen presenting cells. Induced GAD65 antigen presentation activates T-cells, which initiates the downstream events leading to diabetes. In our humanized mice, we have shown downregulation of eukaryotic translation initiation factor 5 A (elF5A), expressed only in actively dividing mammalian cells. In-vivo inhibition of elF5A hypusination by deoxyhypusine synthase (DHS) inhibitor "GC7" was studied; DHS inhibitor alters the pathophysiology in our mouse model by catalyzing the crucial hypusination and the rate-limiting step of elF5A activation...
February 7, 2019: Scientific Reports
Edward A El-Am, Angela Dispenzieri, Rowlens M Melduni, Naser M Ammash, Roger D White, David O Hodge, Peter A Noseworthy, Grace Lin, Sorin V Pislaru, Alexander C Egbe, Martha Grogan, Vuyisile T Nkomo
BACKGROUND: Arrhythmias, conduction abnormalities, and intracardiac thrombus are common in patients with cardiac amyloidosis (CA). Outcomes of direct-current cardioversion (DCCV) for atrial arrhythmias in patients with CA are unknown. OBJECTIVES: This study sought to examine DCCV procedural outcomes in patients with CA. METHODS: Patients with CA scheduled for DCCV for atrial arrhythmias from January 2000 through December 2012 were identified and matched 2:1 with control patients by age, sex, type of atrial arrhythmia, and date of DCCV...
February 12, 2019: Journal of the American College of Cardiology
Kasturi Barik, Syed Naser Daimi, Rhiannon Jones, Joydeep Bhattacharya, Goutam Saha
The perception of an external stimulus not only depends upon the characteristics of the stimulus but is also influenced by the ongoing brain activity prior to its presentation. In this work, we directly tested whether spontaneous electrical brain activities in prestimulus period could predict perceptual outcome in face pareidolia (visualizing face in noise images) on a trial-by-trial basis. Participants were presented with only noise images but with the prior information that some faces would be hidden in these images, while their electrical brain activities were recorded; participants reported their perceptual decision, face or no-face, on each trial...
February 5, 2019: Brain Informatics
Mohammad Saadati, Saber Azami-Aghdash, Mahdieh Heydari, Naser Derakhshani, Ramin Rezapour
Objective: To perform a systematic review and meta-analysis of self-immolation epidemiology and characteristics in Iran. Methods: This was a systematic review and meta-analysis study. PubMed, Scopus, Web of science and Science Direct were searched for English literature and SID and Magiran for Persian in the time period of 2000 to 2016. The retrieved studies were screened and reviewed then quality assessed. Random Effect model was applied for meta-analysis. The qualitative data were analyzed by content analysis method...
January 2019: Bulletin of Emergency and Trauma
Mona Zamanian-Azodi, Mostafa Rezaei-Tavirani, Mohammad Mahboubi, Mohsen Hamidpour, Majid Rezaei Tavirani, Mostafa Hamdieh, Mohammad Rostami-Nejad, Naser Nejadi, Mohammad Kamran Derakhshan
Introduction: Many genetic studies are conducted on Obsessive-Compulsive Disorder (OCD). however, a high-throughput examination of proteome profile of this severe disease has not been performed yet. Methods: Here, the proteomic study of OCD patients' serum samples was conducted by the application of Two-Dimensional Electrophoresis (2DE) followed by Mass Spectrometry (MALDI-TOF-TOF). Results: A total of 240 protein spots were detected and among them, five significant differentially expressed protein spots with the fold change of ≥1...
September 2018: Basic and Clinical Neuroscience
Talal Alzahrani, Abdulelah Nuqali, Nejat Naser, Amar R Jariwala
We present a patient with Crohn's disease under treatment with adalimumab who developed acute myeloid leukaemia (AML) with core-binding factor beta gene rearrangement. This case report emphasises the importance of long-term close follow-up of patients receiving adalimumab because of the increased risk of developing AML and other malignancies.
February 3, 2019: BMJ Case Reports
Tohid Vahdatpour, Ali Nokhodchi, Parvin Zakeri-Milani, Mehran Mesgari-Abbasi, Naser Ahmadi-Asl, Hadi Valizadeh
AIMS/INTRODUCTION: Peptides are considered as quasi-hormones and effective molecules for regulation of the cells function and metabolic disorders prevention. Di- and tripeptides with the ability to gastrointestinal absorption have been proposed to prevent diabetes progression. MATERIALS AND METHODS: Small peptides with different sequences of specific amino acids were synthesized based on a solid phase peptide synthesis (SPPS) protocol as well as carnosine (A) and glutathione (B) were examined for the prevention of diabetes induced by multiple low-dose of streptozotocin (MLDS) in mice...
February 2, 2019: Journal of Diabetes Investigation
Reza Mohebbati, Maryam Paseban, Mohammad Soukhtanloo, Mohammad Jalili-Nik, Mohammad Naser Shafei, Amirali Jahani Yazdi, Abolfazl Khajavi Rad
BACKGROUND: Due to antioxidant effects of Zataria multiflora (ZM) and Carvacrol (CAR) in many cases and the prominent role of reactive oxygen species (ROS) in hepatotoxicity induced by Adriamycin (ADR), the aim of this study is to investigate the effects of ZM and CAR on ADR-induced hepatotoxicity. METHODS: Twenty four male Wistar rats were randomly divided into four groups including: 1)Control, 2)Adriamycin (ADR), 3,4) ZM + ADR and CAR + ADR that received ZM and CAR for 28 consecutive days...
December 2018: Biomedical Journal
Mehran Alavi, Naser Karimi
Thymol and usnic acid as the important secondary metabolites of respectively Artemisia haussknechtii and Protoparmeliopsis muralis were used for reduction and stabilizing of AgNO3 and CuSO4 in metal nanoparticles (MNPs) biosynthesis process. Antibacterial effects of prepared Ag-thymol (ATNPs), Ag-usnic acid (AUNPs), Cu-thymol (CTNPs), and Cu-usnic acid (CUNPs) on multi drug resistant (MDR) bacteria including methicillin-resistant Staphylococcus aureus (MRSA) (gram positive), Acinetobacter baumannii (A52), and Klebsiella pneumonia (K38) (gram negative) were compared with thymol, usnic acid, AgNO3 , CuSO4 , and tetracycline...
January 29, 2019: International Journal of Biological Macromolecules
Kim De Paepe, Joran Verspreet, Mohammad Naser Rezaei, Silvia Hidalgo Martinez, Filip Meysman, Davy Van de Walle, Koen Dewettinck, Jeroen Raes, Christophe Courtin, Tom Van de Wiele
Undigestible, insoluble food particles, such as wheat bran, are important dietary constituents that serve as a fermentation substrate for the human gut microbiota. The first step in wheat bran fermentation involves the poorly studied solubilization of fibers from the complex insoluble wheat bran structure. Attachment of bacteria has been suggested to promote the efficient hydrolysis of insoluble substrates, but the mechanisms and drivers of this microbial attachment and colonization, as well as subsequent fermentation remain to be elucidated...
2019: PeerJ
Naser Ojaroudi Parchin, Haleh Jahanbakhsh Basherlou, Yasir I A Al-Yasir, Atta Ullah, Raed A Abd-Alhameed, James M Noras
In this study, we propose a design of a multi-band slot antenna array applicable for fourth-generation (4G) and fifth-generation (5G) smartphones. The design is composed of double-element square-ring slot radiators fed by microstrip-line structures for easy integration with radio frequency (RF)/microwave circuitry. The slot radiators are located on the corners of the smartphone printed circuit board (PCB) with an overall dimension of 75 × 150 mm². The proposed multiple-input multiple-output (MIMO) antenna is designed to meet the requirements of 4G and 5G mobile terminals with essential bandwidth for higher data rate applications...
January 23, 2019: Sensors
Seyedeh Maryam Hafezian, Seyed Naser Azizi, Pourya Biparva, Ahmadreza Bekhradnia
Sulforaphane, a promising phytochemical, has received much attention in recent decades as a potential anticarcinogenic compound. In this research work, a novel, specific and affordable method has been developed for the separation and purification of natural sulforaphane from broccoli extract using SBA-15 mesoporous silica. SBA-15 was found to be the most efficient in the purification of sulforaphane compared to some of the conventionally used adsorbents and zeolites. The nanoparticles of SBA-15 mesoporous silica were synthesized using the hydrothermal method from natural amorphous silica extracted from rice husk ash with a silica purity of 96%...
January 11, 2019: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
Josée G Lavoie, Sabrina T Wong, Naser Ibrahim, John D O'Neil, Michael Green, Amanda Ward
BACKGROUND: Since the 1960s, the federal government has been providing or funding a selection of community-based primary healthcare (PHC) programs on First Nations reserves. A key question is whether local access to PHC can help address health inequities in First Nations on-reserve communities in British Columbia (BC). OBJECTIVES: This paper examines whether hospitalization for Ambulatory Care Sensitive Conditions (1) can be used as a proxy measure for the organization of PHC in First Nations reserve areas; and (2) is associated with premature mortality rates...
January 18, 2019: BMC Health Services Research
Abu Mohd Naser, Solaiman Doza, Mahbubur Rahman, Kazi Matin Uddin Ahmed, Mohammed Shahid Gazi, Gazi Raisul Alam, Mohammed Rabiul Karim, Golam Kibria Khan, Mohammed Nasir Uddin, Mohammed Ilias Mahmud, Ayse Ercumen, Julia Rosenbaum, Jonathan Annis, Stephen P Luby, Leanne Unicomb, Thomas F Clasen
We evaluated the effectiveness of a sand barrier around latrine pits in reducing fecal indicator bacteria (FIB) leaching into shallow groundwater. We constructed 68 new off-set single pit pour flush latrines in Galachipa sub-district of coastal Bangladesh. We randomly assigned 34 latrines to include a 50-cm thick sand barrier under and around the pit and 34 received no sand barrier. Four monitoring wells were constructed around each pit to collect water samples at baseline and subsequent nine follow-up visits over 24 months...
January 17, 2019: Environmental Science & Technology
Reza Mohebbati, Maryam Paseban, Farimah Beheshti, Mohammad Soukhtanloo, Mohammad Naser Shafei, Hasan Rakhshandeh, Abolfazl Khajavi Rad
Objectives: The hepatotoxicity induced by Acetaminophen (AAP) mostly mediated by effect on oxidative stress parameters. The Zataria multiflora (Z.M) is an herbal medicine with well-known antioxidant effect. The aim of this study is investigation of preventive effects of Z.M and Carvacrol (CAR) on AAP-induced hepatotoxicity in rats. Methods: Rats were randomly divided into four groups including: 1) Control, 2) Acetaminophen (AAP), 3) and 4) CAR. The saline, Z.M (200 mg/kg) and CAR (20 mg/kg) were administrated orally for 6 days, after that AAP (600 mg/kg) was administrated in the 7th day...
December 2018: Journal of Pharmacopuncture
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