Read by QxMD icon Read

Resting state network

Jie Fan, Ivy F Tso, Daniel F Maixner, Tessa Abagis, Luis Hernandez-Garcia, Stephan F Taylor
BACKGROUND: The present study tested the hypothesis that network segregation, a graph theoretic measure of functional organization of the brain, is correlated with treatment response in patients with major depressive disorder (MDD) undergoing repetitive transcranial magnetic stimulation (rTMS). METHODS: Network segregation, calculated from resting state functional magnetic resonance imaging scans, was measured in 32 patients with MDD who entered a sham-controlled, double-blinded, randomized trial of rTMS to the left dorsolateral prefrontal cortex, and a cohort of 20 healthy controls (HCs)...
February 13, 2019: NeuroImage: Clinical
Shreyas Harita, Gabriela Ioachim, Jocelyn Powers, Patrick W Stroman
Resting-state functional magnetic resonance imaging (rs-fMRI) has been used to investigate networks within the cortex and has also provided some insight into the networks present in the brainstem (BS) and spinal cord (SC). The purpose of this study was to investigate resting-state blood oxygenation-level dependent (BOLD) fluctuations in the BS/SC and to identify resting-state networks (RSNs) across these regions. Resting-state BOLD fMRI data were obtained from the entire BS and cervical SC in 16 healthy participants, at 3 T, with T2 -weighted single-shot fast spin-echo imaging...
February 15, 2019: Neuroscience
Patrícia Klobušiaková, Radek Mareček, Jan Fousek, Eva Výtvarová, Irena Rektorová
BACKGROUND: Cognitive impairment in Parkinson's disease (PD) is associated with altered connectivity of the resting state networks (RSNs). Longitudinal studies in well cognitively characterized PD subgroups are missing. OBJECTIVES: To assess changes of the whole-brain connectivity and between-network connectivity (BNC) of large-scale functional networks related to cognition in well characterized PD patients using a longitudinal study design and various analytical methods...
2019: Journal of Alzheimer's Disease: JAD
Akihiro Takamiya, Jinichi Hirano, Bun Yamagata, Shigeki Takei, Taishiro Kishimoto, Masaru Mimura
Introduction : Electroconvulsive therapy (ECT) has antidepressant effects, but it also has possible cognitive side effects. The effects of ECT on neuronal oscillatory pattern and phase synchronization, and the relationship between clinical response or cognitive change and electroencephalogram (EEG) measurements remain elusive. Methods : Individuals with unipolar depressive disorder receiving bilateral ECT were recruited. Five minutes of resting, eyes-closed, 19-lead EEG recordings were obtained before and after a course of ECT...
2019: Frontiers in Human Neuroscience
Raimon H R Pruim, Christian F Beckmann, Marianne Oldehinkel, Jaap Oosterlaan, Dirk Heslenfeld, Catharina A Hartman, Pieter J Hoekstra, Stephen V Faraone, Barbara Franke, Jan K Buitelaar, Maarten Mennes
BACKGROUND: Attention-deficit/hyperactivity disorder (ADHD) is a heterogeneous neurodevelopmental disorder, putatively induced by dissociable dysfunctional biobehavioral pathways. Here, we present a proof-of-concept study to parse ADHD-related heterogeneity in its underlying neurobiology by investigating functional connectivity across multiple brain networks to 1) disentangle categorical diagnosis-related effects from dimensional behavior-related effects and 2) functionally map these neural correlates to neurocognitive measures...
December 20, 2018: Biological Psychiatry: Cognitive Neuroscience and Neuroimaging
Xiao Wang, Wei Liao, Shaoqiang Han, Jiao Li, Yan Zhang, Jingping Zhao, Huafu Chen
Schizophrenia (SCZ) is a severe neuropsychiatric disease associated with dysfunction of brain regions and networks. Recent, functional magnetic resonance imaging (fMRI) studies have determined that the global signal (GS) is an important source of the local neuronal activity. However, the dynamics of this effect in SCZ remains unknown. To address this issue, 39 drug-naive patients with early-onset schizophrenia (EOS) and 31 age-, gender- and education-matched healthy controls underwent resting-state fMRI scans...
February 14, 2019: Schizophrenia Research
Nicolai Franzmeier, Anna Rubinski, Julia Neitzel, Yeshin Kim, Alexander Damm, Duk L Na, Hee Jin Kim, Chul Hyoung Lyoo, Hana Cho, Sofia Finsterwalder, Marco Duering, Sang Won Seo, Michael Ewers
In Alzheimer's disease, tau pathology spreads hierarchically from the inferior temporal lobe throughout the cortex, ensuing cognitive decline and dementia. Similarly, circumscribed patterns of pathological tau have been observed in normal ageing and small vessel disease, suggesting a spatially ordered distribution of tau pathology across normal ageing and different diseases. In vitro findings suggest that pathological tau may spread 'prion-like' across neuronal connections in an activity-dependent manner. Supporting this notion, functional brain networks show a spatial correspondence to tau deposition patterns...
February 15, 2019: Brain: a Journal of Neurology
Furong Zhu, Yi Liu, Feng Liu, Ru Yang, Huabing Li, Jindong Chen, David N Kennedy, Jingping Zhao, Wenbin Guo
Disrupted functional asymmetry has been implicated in schizophrenia. However, it remains unknown whether disrupted functional asymmetry originates from intra-hemispheric and/or inter-hemispheric functional connectivity (FC) in the patients, and whether it starts at very early stage of psychosis. Seventy-six patients with first-episode, drug-naive schizophrenia, 74 subjects at ultra-high risk for psychosis (UHR), and 71 healthy controls underwent resting-state functional magnetic resonance imaging. The 'Parameter of asymmetry' (PAS) metric was calculated and support vector machine (SVM) classification analysis was applied to analyze the data...
February 12, 2019: European Neuropsychopharmacology: the Journal of the European College of Neuropsychopharmacology
Jingjing Xu, Minming Zhang
PURPOSE: To determine the association between functional connectivity (FC) of functional-segmented anterior and posterior portions of the hippocampus and performance on verbal and visual memory tests in a young, healthy population. METHODS: We recruited 100 healthy participants in the age of 19-29. Resting state fMRI data were acquired and voxel-wise correlation analysis was performed to functionally divide the hippocampus. We investigated the inter-hemispheric hippocampal-cortical functional connectivity after the participants took the assessment of episodic memory using verbal (California Verbal Learning Test II, CVLT-II) and visual subtests (Rey-Osterrieth Complex Figure, ROCF)...
February 12, 2019: Behavioural Brain Research
Jatin G Vaidya, Alexis L Elmore, Alexander Wallace, Douglas R Langbehn, John R Kramer, Samuel Kuperman, Daniel S O'Leary
OBJECTIVE: Youth with a family history of alcohol use disorder (family history positive; FHP) are at increased risk for developing maladaptive substance use relative to family history negative (FHN) peers. Building on earlier studies demonstrating morphological differences and distinct patterns of neural activation in FHP, the purpose of the present study was to investigate differential intrinsic functional connectivity among brain networks indexing premorbid risk of developing alcohol use disorder (AUD)...
February 13, 2019: Journal of the American Academy of Child and Adolescent Psychiatry
Maria Seidel, Viola Borchardt, Daniel Geisler, Joseph A King, Ilka Boehm, Sophie Pauligk, Fabio Bernardoni, Ronald Biemann, Veit Roessner, Martin Walter, Stefan Ehrlich
OBJECTIVE: Functional MRI studies have repeatedly shown alterations in patients with anorexia nervosa (AN). These alterations might be driven by baseline signal characteristics such as the (fractional) amplitude of low frequency fluctuations (fALFF/ALFF), as well as regional signal consistency [ie. regional homogeneity (ReHo)] within circumscribed brain regions. Previous studies have also demonstrated grey matter (pseudo-) atrophy in underweight AN. Here we study fALFF/ALFF and ReHo in predominantly adolescent patients with AN, while taking grey matter changes into consideration...
February 15, 2019: Journal of the American Academy of Child and Adolescent Psychiatry
Nina Levar, Tessa J Van Doesum, Damiaan Denys, Guido A Van Wingen
In recent years, resting-state (RS) networks and RS function have received increased attention, highlighting their importance in both cognitive function and psychopathology. The neurochemical substrates underlying RS networks and their interactions, however, have not yet been well established. Even though prior research has provided first evidence for a negative association between brain GABA levels and RS connectivity, these findings have been limited to within network connectivity, and not network interactions...
February 14, 2019: Scientific Reports
Elise R Facer-Childs, Brunno M Campos, Benita Middleton, Debra J Skene, Andrew P Bagshaw
INTRODUCTION: Functional connectivity (FC) of the human brain's intrinsically connected networks underpins cognitive functioning and disruptions of FC are associated with sleep and neurological disorders. However, there is limited research on the impact of circadian phenotype and time of day on FC. STUDY OBJECTIVES: The aim of this study was to investigate resting state FC of the default mode network (DMN) in Early and Late circadian phenotypes over a socially constrained day...
February 15, 2019: Sleep
Chelsea M Kaplan, Andrew Schrepf, Deniz Vatansever, Tony E Larkin, Ishtiaq Mawla, Eric Ichesco, Laura Kochlefl, Steven E Harte, Daniel J Clauw, George A Mashour, Richard E Harris
A critical component of brain network architecture is a robust hub structure, wherein hub regions facilitate efficient information integration by occupying highly connected and functionally central roles in the network. Across a wide range of neurological disorders, hub brain regions seem to be disrupted, and the character of this disruption can yield insights into the pathophysiology of these disorders. We applied a brain network-based approach to examine hub topology in fibromyalgia, a chronic pain condition with prominent central nervous system involvement...
January 16, 2019: Pain
Xin Huang, Han-Dong Dan, Fu-Qing Zhou, Qin-Qin Deng, Yin Shen
Previous neuroimaging studies have shown that the long-term effects of peripheral vision loss lead to functional and morphological reorganization in visual cortices. However, it has not been determined whether whole-brain functional network centrality changes occur during peripheral vision loss. This study aimed to investigate functional network centrality and connectivity changes in individuals with peripheral vision loss because of retinitis pigmentosa (RP) by using voxel-wise degree centrality (DC) and seed-based resting-state functional connectivity (rsFC) methods...
March 6, 2019: Neuroreport
Zhifu Shen, Siyi Yu, Minyu Wang, Tianwei She, Ya Yang, Yanan Wang, Wei Wei, Xiaoli Guo, Youping Hu, Fanrong Liang, Jie Yang
Neuroimaging studies have manifested functional abnormalities in pain-related brain regions in patients with primary dysmenorrhea (PDM). However, as the key region in brain pain matrix, whether and how the amygdala functional network alteration in PDM is unclear. In this study, we aimed to investigate the intrinsic amygdala functional connectivity (AFC) network alteration in patients with PDM during ovulatory period. Thirty-six PDM patients and 35 matched healthy controls were enrolled in this study. The AFC was constructed using amygdala-based functional connectivity using resting-state functional MRI data...
February 11, 2019: Neuroreport
Hadeer Emam, David C Steffens, Godfrey Pearlson, Lihong Wang
OBJECTIVE: Previous studies of imaging predictors on acute treatment response in late life depression (LLD) demonstrated that poor response to selective serotonin reuptake inhibitors (SSRI) is associated with pre-treatment low functional connectivity (FC) within executive control network and high FC within default-mode network including the ventromedial prefrontal cortex (vmPFC). However, there is less research in regional resting-state functional activity that explains FC changes related to SSRI response...
February 13, 2019: International Journal of Geriatric Psychiatry
Chuanyin Zhan, Hua-Jun Chen, Yong-Qing Gao, Tian-Xiu Zou
Purpose: Whole-brain functional network analysis is an emerging methodology for exploring the mechanisms underlying hepatic encephalopathy (HE). This study aimed to identify the brain subnetwork that is significantly altered within the functional connectome in minimal HE (MHE), the earliest stage of HE. Materials and Methods: The study enrolled 19 cirrhotic patients with MHE and 19 controls who underwent the resting-state functional magnetic resonance imaging and cognitive assessment based on the Psychometric Hepatic Encephalopathy Score (PHES)...
2019: Frontiers in Neurology
Adellah Sariah, Zhening Liu, Weidan Pu, Haihong Liu, Zhimin Xue, Xiaojun Huang
Background: A number of neuroimaging studies have investigated structural, metabolic, and functional connectivity changes in betel quid (BQ) chewers. We present a systematic review of neuroimaging studies with emphasis on key brain systems affected by BQ chewing to bring a better understanding on the neuro mechanisms involved in BQD. Methods: All BQ neuroimaging studies were identified by searching PubMed, EMBASE, and Google scholar for English articles published until March 2018 using the key words: Betel-quid, resting state, functional MRI, structural MRI, diffusion tensor imaging (DTI), and betel quid dependence basing on the PRISMA criteria...
2019: Frontiers in Psychiatry
Chandra Sripada, Mike Angstadt, Saige Rutherford, Daniel Kessler, Yura Kim, Mike Yee, Elizaveta Levina
Resting state functional connectomes are massive and complex. It is an open question, however, whether connectomes differ across individuals in a correspondingly massive number of ways, or whether most differences take a small number of characteristic forms. We systematically investigated this question and found clear evidence of low-rank structure in which a modest number of connectomic components, around 50-150, account for a sizable portion of inter-individual connectomic variation. This number was convergently arrived at with multiple methods including estimation of intrinsic dimensionality and assessment of reconstruction of out-of-sample data...
February 13, 2019: Scientific Reports
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"