Christina J Sperna Weiland, Xavier J N M Smeets, Wietske Kievit, Robert C Verdonk, Alexander C Poen, Abha Bhalla, Niels G Venneman, Ben J M Witteman, David W da Costa, Brechje C van Eijck, Matthijs P Schwartz, Tessa E H Römkens, Jan Maarten Vrolijk, Muhammed Hadithi, Annet M C J Voorburg, Lubbertus C Baak, Willem J Thijs, Roy L van Wanrooij, Adriaan C I T L Tan, Tom C J Seerden, Yolande C A Keulemans, Thomas R de Wijkerslooth, Wim van de Vrie, Peter van der Schaar, Sven M van Dijk, Nora D L Hallensleben, Ruud L Sperna Weiland, Hester C Timmerhuis, Devica S Umans, Jeanin E van Hooft, Harry van Goor, Hjalmar C van Santvoort, Marc G Besselink, Marco J Bruno, Paul Fockens, Joost P H Drenth, Erwin J M van Geenen
BACKGROUND: Pancreatitis is the most common complication of endoscopic retrograde cholangiopancreatography (ERCP). Prophylactic rectal administration of non-steroidal anti-inflammatory drugs (NSAIDs) is considered as standard of care to reduce the risk of post-ERCP pancreatitis. It has been suggested that aggressive hydration might further reduce this risk. Guidelines already recommend aggressive hydration in patients who are unable to receive rectal NSAIDs, although it is laborious and time consuming...
May 2021: Lancet. Gastroenterology & Hepatology