Marialuisa Zedde, Manuela Napoli, Claudio Moratti, Francesca Romana Pezzella, David Julian Seiffge, Georgios Tsivgoulis, Luigi Caputi, Carlo Salvarani, Danilo Toni, Franco Valzania, Rosario Pascarella
Primary Angiitis of the Central Nervous System (PACNS) is a rare cerebrovascular disease involving the arteries of the leptomeninges, brain and spinal cord. Its diagnosis can be challenging, and the current diagnostic criteria show several limitations. Among the clinical and neuroimaging manifestations of PACNS, intracranial bleeding, particularly intracerebral hemorrhage (ICH), is poorly described in the available literature, and it is considered infrequent. This review aims to summarize the available data addressing this issue with a dedicated focus on the clinical, neuroradiological and neuropathological perspectives...
February 19, 2024: Biomedicines