Hadil Zureigat, Michael T Osborne, Shady Abohashem, Kenechukwu Mezue, Charbel Gharios, Simran Grewal, Alex Cardeiro, Nicki Naddaf, Giovanni Civieri, Taimur Abbasi, Azar Radfar, Wesam Aldosoky, Antonia V Seligowski, Meagan M Wasfy, James Sawalla Guseh, Timothy W Churchill, Rachel P Rosovsky, Zahi Fayad, Anthony Rosenzweig, Aaron Baggish, Roger K Pitman, Karmel W Choi, Jordan Smoller, Lisa M Shin, Ahmed Tawakol
BACKGROUND: The mechanisms underlying the psychological and cardiovascular disease (CVD) benefits of physical activity (PA) are not fully understood. OBJECTIVES: This study tested whether PA: 1) attenuates stress-related neural activity, which is known to potentiate CVD and for its role in anxiety/depression; 2) decreases CVD in part through this neural effect; and 3) has a greater impact on CVD risk among individuals with depression. METHODS: Participants from the Mass General Brigham Biobank who completed a PA survey were studied...
April 23, 2024: Journal of the American College of Cardiology