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Cardiovascular depression

Robert W Yeh, Hector Tamez, Eric A Secemsky, J Aaron Grantham, James Sapontis, John A Spertus, David J Cohen, William J Nicholson, Kensey Gosch, Philip G Jones, Linda R Valsdottir, Jeffrey Bruckel, William L Lombardi, Farouc A Jaffer
OBJECTIVES: This study sought to examine depression prevalence among chronic total occlusion (CTO) patients and compared symptom improvement among depressed and nondepressed patients after percutaneous coronary intervention (PCI). BACKGROUND: Depression in cardiovascular patients is common, but its prevalence among CTO patients and its association with PCI response is understudied. METHODS: Among 811 patients from the OPEN-CTO (Outcomes, Patient Health Status, and Efficiency in Chronic Total Occlusion Hybrid Procedures) registry, we evaluated change in health status between baseline and 1-year post-PCI, as measured by the Seattle Angina Questionnaire (SAQ) and the Rose Dyspnea Score...
March 9, 2019: JACC. Cardiovascular Interventions
Frank Doyle, Kenneth Freedland, Robert Carney, Peter de Jonge, Chris Dickens, Susanne Pedersen, Jan Sorensen, Martin Dempster
BACKGROUND: Depression is common in patients with coronary artery disease (CAD) and is associated with poorer outcomes and higher costs. Several randomised controlled trials (RCTs) targeting depression, of various modalities (including pharmacological, psychotherapeutic and other approaches), have been conducted and summarised in pairwise meta-analytic reviews. However, no study has considered the cumulative evidence within a network, which can provide valuable indirect comparisons and information about the relative efficacy of interventions...
March 16, 2019: Systematic Reviews
Xiao-Huan Zhang, Chong-Yong Li, Qing-Hua Lin, Zhi-Heng He, Feng Feng, Ming-Fang He
AIMS: Liquorice is a widely used herbal medicine for treating various diseases native to southern Europe and parts of Asia. Isoliquiritin (ISL), a licorice root-derived flavonoid, has been reported to exhibit antioxidant, anti-inflammatory, anti-genotoxic activity and anti-depression activities. This study was aimed to explore the pro-angiogenic activity of ISL and explicate the underlying mechanism. MAIN METHODS: In vitro, ISL-treated human umbilical vein endothelial cells (HUVECs) were analyzed for cell viability, cell migration and tube formation...
March 12, 2019: Life Sciences
Nien-Tzu Chang, Ta-Chen Su
BACKGROUND AND AIMS: Inherited familial hypercholesterolemia (FH) increases cardiovascular risks, but perceived depression in FH is unknown. This study aims to explore the association between the FH and perceived depression. METHODS: This study was a hospital-based design, we started to recruit clinical diagnosis of phenotypic FH since 2014 for the Ten Countries Study in the Asia-Pacific region. We consecutively recruited 302 FH patients and other 414 comparison subjects (214 subjects with hypertriglyceridemia and 200 subjects with normal lipid controls) from the special lipid clinic of National Taiwan University Hospital, Taipei...
March 2019: Atherosclerosis. Supplements
Shu-Ting Chen, Shih-Ting Huang, Wen-Yi Shau, Chao-Lun Lai, Jim Z Li, Selwyn Fung, Vicki C Tse, Mei-Shu Lai
BACKGROUND: Despite the recommendations of statins treatment for secondary prevention of atherosclerotic cardiovascular disease (ASCVD), treatment adherence and persistence are still a concern. This study examined the real world practice of long-term adherence and persistence to statins treatment initiated after hospital discharge for ASCVD, and their associated factors in a nationwide cohort. METHODS: Post discharge statin prescriptions between 2006 and 2012 were extracted from the Taiwan National Health Insurance claims database...
March 15, 2019: BMC Cardiovascular Disorders
Louisa G Sylvia, Samantha L Pegg, Steven C Dufour, Jessica A Janos, Emily E Bernstein, Weilynn C Chang, Nathan E Hall, Kristen K Ellard, Andrew A Nierenberg, Thilo Deckersbach
BACKGROUND: Individuals with bipolar disorder (BD) are more likely than the general population to develop risk factors associated with cardiovascular disease, one of the leading causes of morbidity and mortality in this clinical population. To address this disproportionate medical burden, we developed Nutrition Exercise and Wellness Treatment (NEW Tx), a lifestyle intervention for individuals with BD. METHODS: In this study, participants were randomized to NEW Tx (n = 19) or a treatment as usual waitlist (n = 19)...
March 6, 2019: Journal of Affective Disorders
Silvia Lai, Maurizio Muscaritoli, Paola Andreozzi, Alessandro Sgreccia, Sabrina De Leo, Sandro Mazzaferro, Anna Paola Mitterhofer, Marzia Pasquali, Paolo Protopapa, Alessandra Spagnoli, Maria Ida Amabile, Alessio Molfino
OBJECTIVE: Chronic kidney disease (CKD) is a condition with high cardiovascular mortality associated with emerging risk factors, including sarcopenia. Several mechanisms can affect muscle mass, such as vitamin D deficiency, low protein intake, physical inactivity, metabolic acidosis, and inflammation leading to a worsening of cardiovascular outcomes and cognitive function. We aimed to evaluate the prevalence of sarcopenia in CKD patients on conservative and replacement therapy and the associations between sarcopenia and markers of atherosclerosis, endothelial dysfunction, psychological and cognitive function...
December 11, 2018: Nutrition
Stephanie L Harrison, Catherine Lang, Craig Whitehead, Maria Crotty, Julie Ratcliffe, Steve Wesselingh, Maria C Inacio
BACKGROUND: Studies in some high-income countries have reported a potential decline in the prevalence of dementia. Improvements in cardiovascular health may be contributing to this decline. The objective was to examine trends in prevalence of dementia and survival with dementia for people accessing aged care in Australia. METHODS: A retrospective study of older people who accessed long-term care 2008-2014 (n = 348,311) and home care 2005-2014 (n = 188,846) in Australia was developed...
March 15, 2019: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
Philip S Hall, Gregory Nah, Eric Vittinghoff, Donna R Parker, JoAnn E Manson, Barbara V Howard, Gloria E Sarto, Margery L Gass, Shawnita M Sealy-Jefferson, Elena Salmoirago-Blotcher, Marcia L Stefanick, Aladdin H Shadyab, Linda V Van Horn, Ki Park, Nisha I Parikh
Women with history of pregnancy loss (PL) have higher burden of cardiovascular disease (CVD) later in life, yet it is unclear whether this is attributable to an association with established CVD risk factors (RFs). We examined whether PL is associated with CVD RFs and biomarkers in parous postmenopausal women in the Women's Health Initiative, and whether the association between PL and CVD RFs accounted for the association between PL and incident CVD. Linear and logistic regressions were used to estimate associations between baseline history of PL and CVD RFs...
February 22, 2019: American Journal of Cardiology
Alba González-Roz, Diann E Gaalema, Irene Pericot-Valverde, Rebecca J Elliott, Philip A Ades
PURPOSE: Depression is overrepresented in patients with cardiovascular disease and increases risk for future cardiac events. Despite this, depression is not routinely assessed within cardiac rehabilitation. This systematic review sought to examine available depression questionnaires to use within the cardiac population. We assessed each instrument in terms of its capability to accurately identify depressed patients and its sensitivity to detect changes in depression after receiving cardiac rehabilitation...
March 11, 2019: Journal of Cardiopulmonary Rehabilitation and Prevention
Mathilde Kemula
Clinical evaluation of a psoriatic patient. Psoriasis is a frequent and burdening inflammatory dermatosis. It affects the quality of life of patients in a deep and sustained way, even if the disease is not very extensive. As we now have an array of very effective treatments, it is important to be able to evaluate the objective and subjective severity of the dermatosis, in order to choose the optimal therapeutic goal for each patient. Of course, an associated psoriasis arthritis must be sought because it will influence the choice of treatment...
November 2018: La Revue du Praticien
Muhammad Saleem Awan, Muhammad Yousuf Daud, Matiullah Khan, Attique-Ur-Rehman Jehangiri, Rashid Ali, Shaista Jalil
BACKGROUND: Ischemic heart disease is responsible for approximately 1/3 of all global deaths, making it a leading cause of cardiovascular mortality. Non-ST-segment elevation acute coronary syndrome (NSTE-ACS) which is an acute event in spectrum of coronary artery disease is a potentially lifethreatening emergency, makes up for the majority of admissions to a cardiac unit with one-year mortality rate of 23.5%. The objective of this study was to determine the association of degree of ST segment depression on hospital mortality in patients presenting with Non-ST segment elevation myocardial infarction (NSTEMI)...
January 2019: Journal of Ayub Medical College, Abbottabad: JAMC
Halima Umer, Alemayehu Negash, Mengesha Birkie, Asmare Belete
Background: Depression and heart disease are an important public-health problem. Depression is one of the most prevalent and disabling psychiatric disorders with more than three times increased risk among patients with cardiovascular disorders. Objective: To identify the prevalence and associated factors of depressive disorder among adult patients with cardiovascular disease. Methods: Institution based cross-sectional study design was used to conduct this study on 293 study participants attending an outpatient cardiac clinic at Jimma University Teaching Hospital...
2019: International Journal of Mental Health Systems
Corlia Brandt, Elizabeth C Janse van Vuuren
Background: Pelvic organ prolapse (POP) is a multifactorial, poorly understood condition impacting quality of life (QOL). The pathology and aetiology might imply population-specific differences in domains of the International Classification of Function, Disability and Health (ICF). There is, however, a lack of research in this regard in South Africa. Objectives: To describe the dysfunction, activity limitations, participation restrictions and contextual factors in South African women with POP...
2019: South African Journal of Physiotherapy
Leigh Ann Johnson, Stephanie Ellen Large, Haydee Izurieta Munoz, James Richard Hall, Sid E O'Bryant
BACKGROUND: Mexican Americans are at increased risk of developing mild cognitive impairment (MCI) and Alzheimer's disease compared to non-Hispanic whites. This study sought to examine the relationship between vascular risk, depression, and cognition in Mexican American elders. METHODS: Data from 470 (390 normal controls, 80 MCI patients) Mexican Americans enrolled in the Health and Aging Brain among Latino Elders (HABLE) study were used. The cardiovascular risk was assessed by the Framingham Risk Score...
March 12, 2019: Dementia and Geriatric Cognitive Disorders
Jennifer L Furman, Abigail Soyombo, Andrew H Czysz, Manish K Jha, Thomas J Carmody, Brittany L Mason, Philipp E Scherer, Madhukar H Trivedi
Background: Major depressive disorder (MDD) is often comorbid with metabolic diseases such as obesity, cardiovascular disease, and type 2 diabetes. A potential link between these disorders is adiponectin, an adipocyte-derived circulating hormone with insulin-sensitizing, anti-inflammatory, and neuroplasticity effects. Reductions in plasma levels of adiponectin have been reported in both humans with depression and in the chronic-defeat mouse model of depression. However, the predictive value of adiponectin for treatment response to depression has not been determined...
August 2018: Personalized Medicine in Psychiatry
Raleigh Ems, Anisha Garg, Thomas A Ostergard, Jonathan P Miller
Hypertension is the single greatest contributor to human disease and mortality affecting over 75 million people in the United States alone. Hypertension is defined according to the American College of Cardiology as systolic blood pressure (SBP) greater than 120 mm Hg and diastolic blood pressure (DBP) above 80 mm Hg measured on two separate occasions. While there are multiple medication classes available for blood pressure control, fewer than 50% of hypertensive patients maintain appropriate control. In fact, 0...
2019: Frontiers in Neuroscience
Christian Albus, Christoph Herrmann-Lingen, Katrin Jensen, Matthes Hackbusch, Nina Münch, Catharina Kuncewicz, Maurizio Grilli, Bernhard Schwaab, Bernhard Rauch
BACKGROUND: Exercise-based cardiac rehabilitation (ebCR) often includes various psychological interventions for lifestyle change or distress management. However, the additional benefit of specific psychological interventions on depression, anxiety, quality of life, cardiac morbidity and cardiovascular or total mortality is not well investigated. DESIGN: Systematic review and meta-analysis. METHODS: Randomized controlled trials and controlled cohort trials published between January 1995 and October 2017 comparing ebCR with or without pre-specified psychosocial interventions were selected and evaluated on the basis of predefined inclusion and outcome criteria...
March 11, 2019: European Journal of Preventive Cardiology
Michael Weiss, Guido Michels, Frank Eberhardt, Wolfgang Fehske, Stefan Winter, Frank Baer, Yeong-Hoon Choi, Christian Albus, Daniel Steven, Stephan Baldus, Roman Pfister
BACKGROUND: Psychological distress is common in patients with cardiovascular disease and negatively impacts outcome. HYPOTHESIS: Psychological distress is high in acute high risk cardiac patients eligible for a WCD, and associated with low quality of life. Distress is aggravated by WCD. METHODS: Consecutive patients eligible for a WCD were included in the prospective, multicenter "Cologne Registry of External Defibrillator" registry...
2019: PloS One
Marlene S Williams, Roy C Ziegelstein, Una D McCann, Neda F Gould, Tamara Ashvetiya, Dhananjay Vaidya
OBJECTIVE: Depression in patients with cardiovascular disease is associated with increased risk of adverse clinical outcomes. Investigators have searched for potential biobehavioral explanations for this increased risk. Platelet activation and response to serotonin is an attractive potential mechanism. Our objective was to examine platelet serotonin signaling in a group of patients with coronary artery disease and comorbid depression to define the relationship between platelet serotonin signaling and cardiovascular complications...
March 7, 2019: Psychosomatic Medicine
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