Masakiyo Yatomi, Keiichi Akasaka, Shintaro Sato, Mizuki Chida, Mio Kanbe, Hiru Sawada, Itaru Yokota, Ikuo Wakamatsu, Sohei Muto, Mari Sato, Kochi Yamaguchi, Yosuke Miura, Hiroaki Tsurumaki, Reiko Sakurai, Kenichiro Hara, Yasuhiko Koga, Noriaki Sunaga, Hideaki Yamakawa, Hidekazu Matsushima, Sahori Yamazaki, Yukie Endo, Sei-Ichiro Motegi, Takeshi Hisada, Toshitaka Maeno
BACKGROUND: Autoimmune pulmonary alveolar proteinosis (APAP) is a diffuse lung disease that causes abnormal accumulation of lipoproteins in the alveoli; however, its pathogenesis remains unclear. Recently, APAP cases have been reported during the course of dermatomyositis. The combination of these two diseases may be coincidental; however, it may have been overlooked because differentiating APAP from a flare-up of interstitial pneumonia associated with dermatomyositis is challenging. This didactic case demonstrates the need for early APAP scrutiny...
April 8, 2024: BMC Pulmonary Medicine