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Brucella spondylitis

Peng Wu, Yu-Jiao Zhang, Fang Qin, Lan Liu, Shu-Jun Cui
Objective To explore the value of fractional anisotropy(FA) and apparent diffusion coefficient(ADC) in the early diagnosis of intervertebral disc change in patients with Brucella spondylitis(BS) and in the assessment of BS disc changes after treatment and to further investigate the imaging features of BS in its acute,subacute,and chronic stages. Methods Totally 60 serologically or pathologically confirmed BS patients who were treated in the First Hospital Affiliated to Hebei North University(n=20) or ZhangJiakou Infectious Diseases Hospital(n=40) were enrolled...
August 30, 2018: Zhongguo Yi Xue Ke Xue Yuan Xue Bao. Acta Academiae Medicinae Sinicae
W Li, Y H Zhao, J Liu, Y W Duan, M Gao, Y T Lu, L Yao, S L Li
Objective: To compare the characteristics of X-ray, CT and MRI of Brucella spondylitis and tuberculous spondylitis and its significance for differential diagnosis. Methods: A total of 10 cases of Brucella spondylitis and 20 cases of tuberculous spondylitis confirmed from the clinical, laboratory or pathological department were enrolled between January 2014 and August 2017 in the Fifth Affiliated Hospital of Sun Yat-sen University and the Third Affiliated Hospital of Southern Medical University. The CT, MRI findings were retrospectively analyzed to improve the differential diagnosis of these two diseases...
August 7, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
Xin Hua Yin, Zhong Kai Liu, Bao Rong He, Ding Jun Hao
Literature reporting on lumber brucella spondylitis (LBS) is rare, therefore, the purpose of this study was to evaluate the outcomes of one-stage surgical management for lumber brucella spondylitis by anterior debridement, autogenous grafts, and instrumentation. This was a retrospective cohort study including 16 patients with lumber brucella spondylitis by treated from January 2009 to October 2011 in our department. All cases underwent one-stage anterior internal fixation, debridement, and bone fusion; clinical and radiographic results were analyzed and compared...
July 2018: Medicine (Baltimore)
Jee Young Lee, Yongduk Jeon, Mi Young Ahn, Hea Won Ann, In Young Jung, Wooyong Jung, Moo Hyun Kim, Jin Young Ahn, Je Eun Song, Yong Chan Kim, Dong Hyun Oh, Eun Jin Kim, Su Jin Jeong, Nam Su Ku, Hyunsoo Kim, Kyungwon Lee, June Myung Kim, Jun Yong Choi
Brucellosis is a zoonotic infection that is usually transmitted from cattle to humans through ingestion of animal milk, direct contact with animal parts, or inhalation of aerosolized particles. In Korea, brucellosis seem to be transmitted through close contact with blood, fetus, urine, and placenta of domestic cow that has been infected by Brucella abortus, or inhalation of B. arbortus while examining or slaughtering cow. Brucella melitensis infection is rare in Korea and there have been no reported cases of B...
June 2018: Infection & Chemotherapy
Laiyong Tu, Xinmei Liu, Wenfei Gu, Zhenbin Wang, Enfeng Zhang, Aikenmu Kahar, Ge Chu, Jiang Zhao
BACKGROUND We clarified the imaging features of Brucella spondylitis to enhance our understanding of the disease and to minimize misdiagnosis. MATERIAL AND METHODS Imaging data (X-ray, computed tomography [CT], and magnetic resonance imaging [MRI] data) of 72 Brucella spondylitis patients treated from 2010 to 2017 were retrospectively analyzed; diagnoses was made by evaluating laboratory and pathological data. RESULTS X-ray films revealed changes in intervertebral space heights, the number of lateral osteophytes, and bone destruction, which were more severe in the following order: lumbosacral vertebrae (56 cases, 77...
April 29, 2018: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
Man Li, Xingang Zhou, Jingjing Li, Lei Sun, Xiangmei Chen, Peng Wang
It is difficult to diagnose brucellar spondylitis because of its nonspecific clinical, radiological, and histological characteristics. This study aimed to determine whether real-time polymerase chain reaction (PCR) using formalin-fixed paraffin-embedded (FFPE) tissues was superior to conventional serum-based methods for diagnosing brucellar spondylitis.This retrospective study included 31 patients with brucellosis and a control group of 20 people with no history of brucellosis or exposure to Brucella spp. Samples from all patients with brucellar spondylitis were evaluated using Giemsa staining, the standard tube agglutination (STA) test, blood culture, and real-time PCR...
March 2018: Medicine (Baltimore)
Mehmet Tezer, Zafer Orhan, Cagatay Ozturk, Mercan Sarier, Azmi Hamzaoglu
Brucellar spondylitis may be difficult to diagnose. Initial plain radiographs of the spine may show mild degenerative lesions. Although, magnetic resonance imaging of spine is mostly helpful to establish the disease, in some cases, it may lead to misdiagnosis. The aim of this report was to present a case of brucella infection involving the cervical spine that was falsely diagnosed and underwent to surgery for cervical disc herniation. Since the spinal form of brucellosis has no specific symptomatology, a patient has symptoms with mimicking the cervical hernia, with a history of disabling pain more severe than radicular pain, and especially who reside in countries where the disease is endemic, the brucella infection should be kept in mind in the differential diagnosis and specific diagnostic investigations such as brucella agglutination tests should be made before any treatment procedure...
June 2006: European Journal of Orthopaedic Surgery & Traumatology: Orthop├ędie Traumatologie
Guillermo H Giambartolomei, Paula C Arriola Benitez, M Victoria Delpino
Osteoarticular brucellosis is the most common presentation of human active disease although its prevalence varies widely. The three most common forms of osteoarticular involvement are sacroiliitis, spondylitis, and peripheral arthritis. The molecular mechanisms implicated in bone damage have been recently elucidated. B. abortus induces bone damage through diverse mechanisms in which TNF-╬▒ and the receptor activator of nuclear factor kappa-B ligand (RANKL)-the natural modulator of bone homeostasis are involved...
2017: Frontiers in Microbiology
Yangbin Chen, Jun-Song Yang, Tao Li, Peng Liu, Tuan-Jiang Liu, Li-Min He, Li-Xiong Qian, Ding-Jun Hao
STUDY DESIGN: Clinical case series. OBJECTIVE: The aim of this study was to explore the efficacy and safety of one-stage debridement, autogenous bone graft, and instrumentation for lumbar brucella spondylitis (LBS) via a posterior approach. SUMMARY OF BACKGROUND DATA: Reports on LBS are sporadic, and the therapeutic effect and safety of surgical interventions have not been assessed in clinical studies. METHODS: Between January 2012 and January 2014, 24 consecutive patients with symptomatic LBS who underwent a one-stage operation that combined debridement, autogenous bone graft, and instrumentation via a posterior approach were enrolled...
October 1, 2017: Spine
Tao Li, Tao Liu, Zhensong Jiang, Xingang Cui, Jianmin Sun
The present study examined the histopathological and magnetic resonance imaging (MRI) features of pyogenic, brucella and tuberculous spondylitis (PS, BS and TS, respectively). A total of 22 PS, 20 BS and 20 TS patients were included in the study. Histopathological examination was used to assess the lesion structure and composition, and the MRI observation identified the lesion location and signal features. The following histopathological and MRI features were identified significantly more in patients with PS than in patients with BS and TS: Predominant neutrophil infiltration, abnormal intervertebral disk signal, lesions on the ventral and lateral sides of the vertebral bodies, and thick and irregular abscess walls...
October 2016: Experimental and Therapeutic Medicine
Baohui Yang, Hongbo Hu, Jie Chen, Xijing He, Haopeng Li
Objective . To evaluate the clinical, laboratory, and radiological presentation of 16 cases of brucellar spondylitis. Methods . The clinical manifestations, laboratory tests, and imaging findings of 16 patients (aged from 24 to 66 years) with brucellar spondylitis treated between September 2012 and September 2014 at the Second Affiliated Hospital of Xi'an Jiaotong University (Xi'an, China) were retrospectively analyzed. Results . Clinical manifestations included high fever, severe pain, sweating, and fatigue...
2016: BioMed Research International
Fatehi Elnour Elzein, Nisreen Sherbeeni
Brucellosis is one of the commonest zoonotic infections worldwide. The disease is endemic in Saudi Arabia, the Middle East, and the Mediterranean area. Osteoarticular involvement is a frequent manifestation of brucellosis. It tends to involve the sacroiliac joints more commonly; however, spondylitis and peripheral arthritis are increasingly reported. Brucellosis can be overlooked especially in the presence of companion bacteria. Hence, it should be suspected in all patients with septic arthritis in endemic areas or in patients visiting such areas...
2016: Case Reports in Infectious Diseases
Ali Baradaran Bagheri, Koorosh Ahmadi, Niaz Mohamad Jafari Chokan, Bita Abbasi, Reza Akhavan, Ehsan Bolvardi, Somayeh Soroureddin
BACKGROUND: Brucellosis is an endemic zoonotic disease, especially in the Middle East and Mediterranean regions and can involve many organs and tissue. Osteoarticular involvement is the most common complication. Spondylitis is its most prevalent clinical form in adults, and there may be difficult in diagnosis and treatment. In present study, we aimed to assess these diagnostic value of MRI, in patients with spondylitis due to brucella, comparing with clinical and laboratory findings. METHOD: Patients with low back pain who were admitted to Sheikhol-raees MRI center were included in this study...
April 2016: Acta Informatica Medica: AIM
Eun Jung Kim, Su Jin Lee, Eun Young Ahn, Dae Gon Ryu, Yu Hee Choi, Tae Hyun Kim
Brucellosis is a multisystem disease with various clinical symptoms. Neurobrucellosis is a rare but serious manifestation of brucellosis. A 60-year-old man with a previous diagnosis of brucellar spondylitis presented with sudden onset of aphasia and numbness of the right upper extremity. Cerebral angiography showed diffuse narrowing and dilatation on the distal branches of both the anterior cerebral artery (ACA) and the left middle cerebral artery (MCA) which indicated cerebral vasculitis, and the patient's Brucella agglutinin titer was 1:1280...
December 2015: Infection & Chemotherapy
ZhiXun Yin, ErXing He, HongMei Ding, JingChen Chen
INTRODUCTION: Although Brucella spondylitis and Brucella discitis have been frequently reported, Brucella infection of the vertebral arch is rare and has not been previously described. We present the first case of Brucella infection of the thoracic vertebral arch with epidural abscess formation and discuss the clinical key points. CASE PRESENTATION: A 57-year-old man of Han nationality with a history of contact with an isolated sheep stomach 2 months previously was admitted with an undulant fever, night sweats, back pain, and weakness...
October 23, 2015: Journal of Medical Case Reports
Guldal Esendagli-Yilmaz, Omer Uluoglu
Pyogenic spondylitis and discitis are usually seen following a recent infection or surgery. A septic embolus causes an infarcted area within the bone. Pyogenic spondylitis is characterized by edema, vascular leakage, and supportive inflammatory reaction characterized with polymorphonuclear leukocytes. In tuberculosis of the spine, active lesions are characterized by formation of epithelioid granulomas with central caseating necrosis. Mycobacterium tuberculosis can be shown by histochemical stains for acid-fast bacteria or by immunochemistry...
May 2015: Neuroimaging Clinics of North America
Xinming Yang, Xianhong Zuo, Yongli Jia, Yuefei Chang, Peng Zhang, Yixing Ren
OBJECTIVE: To compare the effectiveness between the method of simple posterior debridement combined with bone grafting and fusion and internal fixation and the method of one-stage anterior radical debridement combined with bone grafting and fusion and posterior internal fixation in the treatment of thoracolumbar brucella spondylitis so as to provide the reference for the clinical treatment. METHODS: A retrospective analysis was made on the clinical data of 148 cases of thoracolumbar brucella spondylitis between January 2002 and January 2012...
October 2014: Chinese Journal of Reparative and Reconstructive Surgery
Nazlim Aktug-Demir, Servet Kolgelier, Serap Ozcimen, Sua Sumer, Lutfi S Demir, Ahmet C Inkaya
OBJECTIVES: To determine the diagnostic factors for brucellar spondylitis. METHODS: This retrospective study included 227 consecutive brucellosis patients admitted to the Infectious Diseases and Clinical Microbiology clinics of Adiyaman State Hospital and Adiyaman 82 nd Year State Hospital, Adiyaman, Turkey between January 2010 and December 2012. Acute brucellosis was diagnosed by standard tube agglutination test and/or growth of Brucella spp. in appropriately prepared culture media (Bactec)...
August 2014: Saudi Medical Journal
Zulkif Bozgeyik, Serpil Aglamis, Pinar Gundogan Bozdag, Affan Denk
OBJECTIVE: The aim of this retrospective study was to determine the magnetic resonance imaging (MRI) findings of patients with musculoskeletal brucellosis. MATERIALS AND METHODS: Sixty-eight among 304 patients with musculoskeletal brucellosis, aged 12-82 years (average, 50.2 years), were included in the study. Patients were diagnosed based on clinical findings, Brucella agglutination tests, and MRI findings. MRI was performed to all of the patients with sacroiliitis, spondylitis-spondylodiscitis, and peripheral arthritis...
September 2014: Clinical Imaging
Makram Koubaa, Imed Maaloul, Chakib Marrakchi, Dorra Lahiani, Boussaima Hammami, Zeinab Mnif, Kaireddine Ben Mahfoudh, Adnane Hammami, Mounir Ben Jemaa
BACKGROUND CONTEXT: Brucellosis remains an important economic and public health problem in some parts of the world. The spine is the most common site of musculoskeletal involvement of brucellosis. PURPOSE: Assess the clinical, laboratory, radiological findings, and outcomes of vertebral involvement in brucellosis. STUDY DESIGN: A retrospective study. PATIENT SAMPLE: Thirty-two patients with spinal brucellosis during a period of 21 years (1990-2010) were included...
August 1, 2014: Spine Journal: Official Journal of the North American Spine Society
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