keyword
https://read.qxmd.com/read/37555768/low-frequency-oscillometry-indices-to-assess-ventilation-inhomogeneity-in-cf-patients
#21
JOURNAL ARTICLE
Sotirios Fouzas, Christos Kogias, Maria Gioulvanidou, Aris Bertzouanis, Elisavet-Anna Chrysochoou, Michael Β Anthracopoulos, John Tsanakas, Elpis Hatziagorou
BACKGROUND: The utility of the forced oscillations technique (FOT) in cystic fibrosis (CF) remains uncertain. The aim of this study was to explore the ability of lower-frequency FOT indices, alone and after adjustment for the lung volume, to assess the extent of ventilation inhomogeneity in CF patients with varying disease severity. METHODS: Forty-five children, adolescents, and adults with CF (age 6.9-27 years) underwent spirometry, FOT, and nitrogen multiple-breath washout (N2-MBW) measurements...
August 9, 2023: Pediatric Pulmonology
https://read.qxmd.com/read/37536553/window-of-opportunity-for-respiratory-oscillometry-a-review-of-recent-research
#22
REVIEW
Sabina Kostorz-Nosal, Dariusz Jastrzębski, Anna Błach, Szymon Skoczyński
Oscillometry has been around for almost 70 years, but there are still many unknowns. The test is performed during tidal breathing and is therefore free from patient-dependent factors that could influence the results. The Forced Oscillation Technique (FOT), which requires minimal patient cooperation, is gaining ground, particularly with elderly patients and children. In pulmonology, it is a valuable tool for assessing obstructive conditions (with a distinction between central and peripheral obstruction) and restrictive disorders (intrapulmonary and extrapulmonary)...
October 2023: Respiratory Physiology & Neurobiology
https://read.qxmd.com/read/37514484/single-and-multiple-gate-design-optimization-algorithm-for-improving-the-effectiveness-of-fiber-reinforcement-in-the-thermoplastic-injection-molding-process
#23
JOURNAL ARTICLE
Mattia Perin, Youngbin Lim, Guido A Berti, Taeyong Lee, Kai Jin, Luca Quagliato
Fiber reinforcement orientation in thermoplastic injection-molded components is both a strength as well as a weak point of this largely employed manufacturing process. Optimizing the fiber orientation distribution (FOD) considering the shape of the part and the applied loading conditions allows for enhancing the mechanical performances of the produced parts. Henceforth, this research proposes an algorithm to identify the best injection gate (IG) location/s starting from a 3D model and a user-defined load case...
July 19, 2023: Polymers
https://read.qxmd.com/read/37500257/the-genome-sequence-of-the-champagne-epernay-geisenheim-wine-yeast-reveals-its-hybrid-nature
#24
JOURNAL ARTICLE
Beatrice Bernardi, Florian Michling, Judith Muno-Bender, Katrin Matti, Jürgen Wendland
Lager yeasts are hybrids between Saccharomyces cerevisiae and S. eubayanus. Wine yeast biodiversity, however, has only recently been discovered to include besides pure S. cerevisiae strains also hybrids between different Saccharomyces yeasts as well as introgressions from non-Saccharomyces species. Here we analysed the genome of the Champagne-Epernay-Geisenheim (CEG) wine yeast. This yeast is an allotetraploid (4n-1) hybrid of S. cerevisiae harbouring a substantially reduced S. kudriavzevii genome contributing only 1/3 of a full genome equivalent...
July 27, 2023: FEMS Yeast Research
https://read.qxmd.com/read/37473547/triple-enhanced-raman-scattering-sensors-from-flexible-mxene-au-nanocubes-platform-via-attenuating-the-coffee-ring-effect
#25
JOURNAL ARTICLE
Xin Liu, Alei Dang, Tiehu Li, Tung-Chun Lee, Yiting Sun, Yuhui Liu, Fei Ye, Shuze Ma, Yong Yang, Weibin Deng
Developing substrates that combine sensitivity and signal stability is a major challenge in surface enhanced Raman scattering (SERS) research. Herein, we present a flexible triple-enhanced Raman Scattering MXene/Au nanocubes (AuNCs) sensor fabricated by selective filtration of Ti3 C2 Tx MXene/AuNCs hybrid on the Ti3 C2 Tx MXene membrane and subsequent treatment with 1H,1H,2H,2H-perfluoro-octyltriethoxysilane (FOTS). The resultant superhydrophobic MXene/AuNCs-FOTS membrane not only provides the SERS substrate with environmental stability, but also imparts analyte enrichment to enhance the sensitivity (LOD = 1 × 10-14  M) and reliability (RSD = 6...
July 14, 2023: Biosensors & Bioelectronics
https://read.qxmd.com/read/37443681/bronchiectasis-assessment-in-primary-ciliary-dyskinesia-a-non-invasive-approach-using-forced-oscillation-technique
#26
JOURNAL ARTICLE
Wilfredo De Jesús-Rojas, Luis Reyes-Peña, José Muñiz-Hernández, Patricia Quiles Ruiz de Porras, Jesús Meléndez-Montañez, Marcos J Ramos-Benitez, Ricardo A Mosquera
Primary ciliary dyskinesia (PCD) is an autosomal recessive disorder that results from the dysfunction of motile cilia, which can cause chronic upper and lower respiratory infections leading to bronchiectasis. However, there is a need for additional tools to monitor the progression of bronchiectasis in PCD. The forced oscillation technique (FOT) is an effort-independent lung function test that can be used to evaluate respiratory mechanics. In this retrospective study, we aimed to describe the radiographic findings associated with respiratory impedance (resistance (Rrs) and reactance (Xrs)) measured by FOT in six adult PCD patients and one pediatric with the ( RSPH4A (c...
July 6, 2023: Diagnostics
https://read.qxmd.com/read/37362514/deeper-seated-than-skin-deep-report-of-a-rare-case-of-follicular-occlusion-tetrad-and-a-literature-review
#27
Yilen K Ng-Wong, Blesset Alexander, Mery Bartl, Christine E Loftis, Dina Hammad, Emilia C Dulgheru, Mauricio De La Garza, Aidee C Nunez
Follicular occlusion tetrad (FOT) is a clinical syndrome consisting of hidradenitis suppurativa (HS), acne conglobata (AC), dissecting cellulitis of the scalp (DCS), and pilonidal cyst (PC). These entities typically occur independently, but occasionally present simultaneously comprising FOT. The four components share similar pathophysiology affecting the apocrine glands, follicular hyperkeratinization being the hallmark of each entity. Understanding shared similarities of each disease is paramount for the treatment approach as the relapsing and chronic nature of this syndrome can be burdening to patients...
May 2023: Curēus
https://read.qxmd.com/read/37261706/lung-function-tests-in-infants-and-children
#28
REVIEW
Kana Ram Jat, Sheetal Agarwal
Lung function testing is an essential modality of investigation in children as it provides objective evidence of lung disease/health. With advances in technology, various tests are available that can aid in the diagnosis of lung disease, assess the progression and response to therapy and document the lung development and evolving lung diseases in infants. This narrative review discusses lung function tests in infants and children. Currently, lung function tests can be performed in every age group, from neonates to the elderly...
August 2023: Indian Journal of Pediatrics
https://read.qxmd.com/read/37240114/optimizing-fluid-management-guided-by-volumetric-parameters-in-patients-with-sepsis-and-ards
#29
RANDOMIZED CONTROLLED TRIAL
Evgeniia V Fot, Natalia O Khromacheva, Aleksei A Ushakov, Aleksei A Smetkin, Vsevolod V Kuzkov, Mikhail Y Kirov
We compared two de-escalation strategies guided by either extravascular lung water or global end-diastolic volume-oriented algorithms in patients with sepsis and ARDS. Sixty patients with sepsis and ARDS were randomized to receive de-escalation fluid therapy, guided either by the extravascular lung water index (EVLWI, n = 30) or the global end-diastolic volume index (GEDVI, n = 30). In cases of GEDVI > 650 mL/m2 or EVLWI > 10 mL/kg, diuretics and/or controlled ultrafiltration were administered to achieve the cumulative 48-h fluid balance in the range of 0 to -3000 mL...
May 15, 2023: International Journal of Molecular Sciences
https://read.qxmd.com/read/37227933/a-perfluorocarbon-coated-zrp-cation-exchanger-with-excellent-ammonium-selectivity-and-chemical-stability-an-oral-sorbent-for-end-stage-kidney-disease-eskd
#30
JOURNAL ARTICLE
Evan Richards, Sang-Ho Ye, Stephen R Ash, Lei Li
An oral sorbent to remove NH4 + within the small intestine of end-stage kidney disease (ESKD) patients could reduce blood urea levels and diminish their dialysis treatment burden. But current sorbent materials like amorphous zirconium phosphate particles Zr(HPO4 )2 ·H2 O (ZrP) lack the selectivity to remove NH4 + in water solution with other competing ions. Our previous work found that a gas-permeable, hydrophobic polydimethylsiloxane (PDMS) coating on ZrP improved the material's selectivity for NH4 + ...
May 25, 2023: Langmuir: the ACS Journal of Surfaces and Colloids
https://read.qxmd.com/read/37107890/white-spots-prevention-in-orthodontics-systematic-review-of-the-literature
#31
REVIEW
Assunta Patano, Giuseppina Malcangi, Roberta Sardano, Antonio Mastrodonato, Grazia Garofoli, Antonio Mancini, Alessio Danilo Inchingolo, Daniela Di Venere, Francesco Inchingolo, Gianna Dipalma, Angelo Michele Inchingolo
Early-stage dental demineralization, called white spots (WS), get their name from the characteristic colour that enamel takes on due to the acid attack of salivary cariogenic bacteria. They are often associated with fixed orthodontic therapy (FOT) and, if left untreated, evolve into caries with repercussions on oral health and dental aesthetics. This review aims to identify the most effective prophylaxis strategies to prevent WS during FOT. The search for the reviewed studies was conducted on the Pubmed, Scopus, and Web of Science databases, selecting English-only articles published in the 5 years from January 2018 to January 2023...
April 21, 2023: International Journal of Environmental Research and Public Health
https://read.qxmd.com/read/37107438/changes-in-the-bio-compounds-and-biological-activities-of-eight-whole-grains-fermentation-starter-with-different-oxidized-chin-shin-oolong-teas
#32
JOURNAL ARTICLE
Chih-Feng Wang, Cui-Rou Huang, Ying-Chen Lu
Chin-shin oolong tea is the most widely planted variety in Taiwan. This study fermented eight whole grains fermentation starter (EGS) with light (LOT), medium (MOT), and fully (FOT) oxidized Chin-shin oolong teas for ten weeks. Comparing the three fermentation beverages, it was found that LOT fermentation can obtain the highest catechins (1644.56 ± 60.15 ppm) among the functional and antioxidant components. MOT can obtain the highest glucuronic acid (19,040.29 ± 2903.91 ppm), tannins, total phenols, flavonoids, and angiotensin-converting enzyme (ACE) inhibitory activity...
April 14, 2023: Foods (Basel, Switzerland)
https://read.qxmd.com/read/37106004/thermodynamic-determination-of-the-equilibrium-first-order-phase-transition-line-hidden-by-hysteresis-in-a-phase-diagram
#33
JOURNAL ARTICLE
Keisuke Matsuura, Yo Nishizawa, Markus Kriener, Takashi Kurumaji, Hiroshi Oike, Yoshinori Tokura, Fumitaka Kagawa
In some materials exhibiting field-induced first-order transitions (FOTs), the equilibrium phase-transition line is hidden by the hysteresis region associated with the FOT. In general, phase diagrams form the basis for the study of material science, and the profiles of phase-transition lines separating different thermodynamic phases include comprehensive information about thermodynamic quantities, such as latent heat. However, in a field-induced FOT, the equilibrium phase-transition line cannot be precisely determined from measurements of resistivity, magnetization, etc, especially when the transition is accompanied by large hysteresis...
April 27, 2023: Scientific Reports
https://read.qxmd.com/read/37102656/the-association-between-vitamin-d-intake-with-inflammatory-and-biochemical-indices-and-mortality-in-critically-ill-patients-with-covid-19-a-case-control-study
#34
JOURNAL ARTICLE
Maryam Gholamalizadeh, Faezeh Rabbani, Mina Ahmadzadeh, Azadeh Hajipour, Hayehe Musavi, Khadijeh Abbasi Mobarakeh, Zahra Salimi, Bojlul Bahar, Zahra Mahmoodi, Somayeh Gholami, Samaneh Mirzaei Dahka, Saeid Doaei, Mokammad Esmail Akbari
BACKGROUND: The coronavirus disease-2019 (COVID-19) has become a worldwide health issue with widespread hospitalization and dependence on the intensive care unit (ICU). Vitamin D has a key role in modulating immune cells and modulating the inflammatory responses. This study aimed to investigate the association of vitamin D supplementation with inflammatory, biochemical, and mortality indices in critically ill patients with COVID-19. METHODS: This case-control study was conducted on critically ill COVID-19 patients hospitalized in the ICU including the survived >30 day patients as the case group and dead patients as the control group...
April 2023: Immunity, Inflammation and Disease
https://read.qxmd.com/read/37071965/modified-stainless-steel-wires-with-superwettability-for-highly-efficient-in-tube-solid-phase-microextraction
#35
JOURNAL ARTICLE
Ya-Ning Wang, Yu-Ping Zhang, Wan-Li You, LingBo Qu, De-Liang Chen, Yuan Chen, Jun Chen
Construction of different surface wettability is meaningful for the interaction between the sorbent surface and target components. In the current study, four kinds of stainless-steel wires (SSWs) with different hydrophobic/hydrophilic property were prepared and used as the absorbents to enrich the target compounds with different polarity. Comparative extraction of six non-polar polycyclic aromatic hydrocarbons (PAHs) and six polar estrogens was carried out by in-tube solid phase microextraction (IT-SPME). The results showed that two SSWs with the superhydrophobic surfaces exhibited high extraction capacity to the non-polar PAHs with the superior enrichment factor (EF) in the range of 29-672 and 57-744, respectively...
April 12, 2023: Journal of Chromatography. A
https://read.qxmd.com/read/37062974/f1-taught-orthopaedic-teaching-programme-for-students-fots
#36
JOURNAL ARTICLE
Prakrit Raj Kumar, Yousuf Hashmi, William Beedham, Ranya Vardini Kumar, Simon Fleming
INTRODUCTION: The COVID-19 pandemic has impacted students learning, with the time off resulting in students 'de-skilling', increasing concerns for upcoming observed structured clinical examinations. Foundation Year 1 (F1) doctors (F1s), despite being expected to teach, rarely receive formal preparation, with COVID-19 exacerbating opportunities to practice. As such, a national orthopaedic teaching programme was designed to provide F1s with opportunities to develop their teaching skills and to synergistically teach medical students how to perform clinical orthopaedic examinations...
September 1, 2022: Postgraduate Medical Journal
https://read.qxmd.com/read/37059986/no-association-between-in-utero-exposure-to-emissions-from-a-coalmine-fire-and-post-natal-lung-function
#37
JOURNAL ARTICLE
Emily J Hemstock, Rachel E Foong, Graham L Hall, Amanda J Wheeler, Shyamali C Dharmage, Marita Dalton, Grant J Williamson, Caroline Gao, Michael J Abramson, Fay H Johnston, Graeme R Zosky
BACKGROUND AND OBJECTIVE: Studies linking early life exposure to air pollution and subsequent impaired lung health have focused on chronic, low-level exposures in urban settings. We aimed to determine whether in utero exposure to an acute, high-intensity air pollution episode impaired lung function 7-years later. METHOD: We conducted a prospective cohort study of children who lived in the vicinity of a coalmine fire. Respiratory function was measured using the forced oscillation technique (FOT)...
April 14, 2023: BMC Pulmonary Medicine
https://read.qxmd.com/read/36949784/social-cognition-in-parkinson-s-disease-a-case-control-study
#38
JOURNAL ARTICLE
Govinda Siripurapu, Bhawna Verma, Deblina Biswas, Anandapadmanabhan Reghu, Aayushi Vishnoi, Divya Madathiparambil Radhakrishnan, Arunmozhimaran Elavarasi, Anu Gupta, Venugopalan Yamuna Vishnu, Mamta Bhushan Singh, Rohit Bhatia, Manjari Tripathi, Achal Srivastava, Madakasira Vasantha Padma Srivastava, Roopa Rajan
BACKGROUND: Social cognition is the study of how people make sense of themselves and others. Impairment in several domains of social cognition is increasingly being recognized in Parkinson's disease (PD). OBJECTIVES: We aimed to study multiple domains of social cognition in Indian PD patients using a culturally appropriate, validated instrument. METHODS: We recruited 52 individuals with PD and 31 healthy volunteers (HV) and used the Social Cognition Rating Tools in Indian Setting (SOCRATIS) tool to assess theory of mind (ToM), attributional biases and social cue perception...
March 2023: Movement Disorders Clinical Practice
https://read.qxmd.com/read/36927049/periodontal-microbiological-and-proinflammatory-cytokines-levels-in-fixed-orthodontics-patients-treated-with-photodynamic-therapy-adjunct-to-full-mouth-scaling
#39
JOURNAL ARTICLE
Ali Alqerban, Saeed N Asiri, Rawda Alghabban, Fahad Alharbi, Abdullah Almalki, Ali S Aljhani, Ferdous Bukhary, Rawa Abdelrahim, Fahad Alkhtani, Abdulaziz Samran
Objective: To assess the efficiency of photodynamic therapy (PDT) adjunct to full mouth scaling (FMS) in improving periodontal, microbiological, and proinflammatory cytokines levels in patients undergoing fixed orthodontics treatment (FOT). Materials and methods: The study recruited 60 teenage patients who were undergoing FOT. All the patients were arbitrarily divided into two groups: Group 1, FMS +PDT and Group 2, FMS alone. Plaque scores (PS), bleeding on probing (BOP), and probing depth (PD) were assessed...
March 2023: Photobiomodulation, photomedicine, and laser surgery
https://read.qxmd.com/read/36719777/gender-differences-in-dynamic-functional-network-connectivity-in-pediatric-and-adult-patients-with-attention-deficit-hyperactivity-disorder
#40
JOURNAL ARTICLE
Elijah Agoalikum, Benjamin Klugah-Brown, Hongzhou Wu, Junlin Jing, Bharat B Biswal
Attention-deficit/hyperactivity disorder (ADHD) persistence into adulthood depends on gender, with 60% female and 35% male cases. This study sought to investigate gender differences in dynamic functional network connectivity (FNC) using resting-state functional magnetic resonance imaging data of pediatric ADHD patients (female: N  = 24; 11.02 ± 2.60 years, male: N  = 20;11.87 ± 2.62 years) and adult ADHD patients (female = 19; 31...
March 27, 2023: Brain Connectivity
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