keyword
https://read.qxmd.com/read/38505920/employing-multicolor-melting-curve-analysis-to-rapidly-identify-non-tuberculous-mycobacteria-in-patients-with-bronchiectasis-a-study-from-a-pulmonary-hospital-in-the-fuzhou-district-of-china-2018-2022
#1
JOURNAL ARTICLE
Mintao Zheng, Xinchao Chen, Qiaoqian Chen, Xiaohong Chen, Mingxiang Huang
Non-tuberculous mycobacteria (NTM) infection is common in bronchiectasis, with rising incidence globally. However, investigation into NTM in bronchiectasis patients in China remains relatively limited. This work aimed to identify and understand the features of NTM in bronchiectasis patient in Fuzhou district of China. The pulmonary samples were collected from 281 bronchiectasis patients with suspected NTM infection in Fuzhou, 2018-2022. MPB64 antigen detection was employed for the preliminary evaluation of NTM...
2024: Critical Reviews in Immunology
https://read.qxmd.com/read/38499001/pectoralis-muscle-area-as-a-predictor-of-mortality-in-patients-hospitalized-with-bronchiectasis-exacerbation
#2
JOURNAL ARTICLE
Hyewon Seo, Seung-Ick Cha, Jongmin Park, Jae-Kwang Lim, Won Kee Lee, Ji-Eun Park, Sun Ha Choi, Yong Hoon Lee, Seung-Soo Yoo, Shin-Yup Lee, Jaehee Lee, Chang-Ho Kim, Jae-Yong Park
INTRODUCTION: Data on factors related to mortality in patients with bronchiectasis exacerbation are insufficient. Computerized tomography (CT) can measure the pectoralis muscle area (PMA) and is a useful tool to diagnose sarcopenia. This study aimed to evaluate whether PMA can predict mortality in patients with bronchiectasis exacerbation. METHODS: Patients hospitalized due to bronchiectasis exacerbation at a single center were retrospectively divided into survivors and non-survivors based on 1-year mortality...
March 18, 2024: Respiration; International Review of Thoracic Diseases
https://read.qxmd.com/read/38485676/biofilm-formation-in-mycobacterial-genus-mechanism-of-biofilm-formation-and-anti-mycobacterial-biofilm-agents
#3
JOURNAL ARTICLE
Sina Nasrollahian, Hassan Pourmoshtagh, Sahar Sabour, Nahal Hadi, Taher Azimi, Saeed Soleiman-Meigooni
Mycobacterium tuberculosis, Mycobacterium leprae, and non-tuberculous mycobacteria (NTM) are among the most significant human pathogens within the Mycobacterium genus. These pathogens can infect people who come into contact with biomaterials or have chronic illnesses. A characteristic pathogenic trait of mycobacteria is the development of biofilms, which involves several molecules, such as the GroEL1 chaperone, glycopeptidolipids, and shorter-chain mycolic acids. Bacterial behavior is influenced by nutrients, ions, and carbon sources, which also play a regulatory role in biofilm development...
March 11, 2024: Current Pharmaceutical Biotechnology
https://read.qxmd.com/read/38461090/-bronchial-involvement-in-granulomatosis-with-polyangiitis
#4
JOURNAL ARTICLE
R Batton, P Le Guen, A Cazes, M-P Debray, C Taillé
No abstract text is available yet for this article.
March 8, 2024: Revue des Maladies Respiratoires
https://read.qxmd.com/read/38455609/pneumonectomy-for-severe-post-tuberculosis-bronchiectasis-a-successful-of-case-report-and-review-of-the-long-term-outcome
#5
JOURNAL ARTICLE
Putri O Zulfa, Yopie A Habibie
Limited clinical intervention studies highlight the absence of evidence-based international guidelines for effectively managing post-tuberculosis lung disease, emphasizing bronchiectasis. The aim of this study was to describe a case of left pneumonectomy for severe post-tuberculosis cystic bronchiectasis and to provide a review of the post-surgical mortality rate, complications, survival rate, and the patient's quality of life following the pneumonectomy procedure. A 36-year-old Indonesian male smoker presented with worsening breathing difficulties and fever...
December 2023: Narra J
https://read.qxmd.com/read/38455273/case-series-of-complicated-bronchopulmonary-lophomoniasis-differential-diagnosis-of-tuberculosis
#6
Cristian Morán-Mariños, Juan Salas López, Felix Llanos-Tejada, Renato Casanova-Mendoza, Renzo Villanueva-Villegas, Antonella Chavez-Huamani, Kenneth G Vargas-Ponce, Margaret Condori-Zevallos
Pulmonary lophomoniasis is a rare and life-threatening disease, most commonly reported across Asian and Latin American countries. Here, we have reported two cases of pulmonary lophomoniasis presenting with atypical manifestations. Case #1 represents a 19-year-old male patient with clinical characteristics suggestive of tuberculosis, presenting with hemoptysis and receiving antituberculosis treatment. Case #2 represents a 69-year-old man with post-tuberculosis pulmonary disease with cystic bronchiectasis presenting with polymicrobial co-infection...
2024: European Clinical Respiratory Journal
https://read.qxmd.com/read/38449006/clinical-characteristics-and-drug-resistance-of-nocardia-in-henan-china-2017-2023
#7
REVIEW
Yungang Han, Meijin Cheng, Zheng Li, Huihui Chen, Shuang Xia, Yue Zhao, Yali Wang, Wenyi He, Wei Wang
BACKGROUND: The aim of this study was to investigate the clinical features of Nocardia infections, antibiotic resistance profile, choice of antibiotics and treatment outcome, among others. In addition, the study compared the clinical and microbiological characteristics of nocardiosis in bronchiectasis patients and non-bronchiectasis patients. METHODS: Detailed clinical data were collected from the medical records of 71 non-duplicate nocardiosis patients from 2017 to 2023 at a tertiary hospital in Zhengzhou, China...
March 6, 2024: Annals of Clinical Microbiology and Antimicrobials
https://read.qxmd.com/read/38417459/-allergic-bronchopullmonary-aspergillosis-abpa-an-update
#8
JOURNAL ARTICLE
Marcus Joest, Johanna Klein, Daniel Kütting, Dirk Skowasch
Allergic bronchopulmonary aspergillosis (ABPA) is a regular occurrence in everyday pneumology. ABPA should be considered in patients with severe asthma, in mould allergic patients with very high serum IgE levels and in patients with cystic fibrosis. The aim should be to make the diagnosis as early as possible in the course of the disease to avoid late complications such as bronchiectasis and fibrotic lung remodelling. Symptoms are highly variable and rather non-specific, overlapping with those of the underlying primary disease...
March 2024: Pneumologie
https://read.qxmd.com/read/38414309/incidence-and-prevalence-of-chronic-pulmonary-aspergillosis-in-patients-with-post-tuberculosis-lung-abnormality-results-from-a-community-survey-in-north-india
#9
JOURNAL ARTICLE
Kathirvel Soundappan, Inderpaul Singh Sehgal, Nidhi Prabhakar, Samriti Rana, Rajesh Raju, Sahajal Dhooria, Kuruswamy Thurai Prasad, Valliappan Muthu, Shivaprakash M Rudramurthy, Arunaloke Chakrabarti, Mandeep Garg, Ritesh Agarwal
BACKGROUND: Post-tuberculosis lung abnormality (PTLA) is the most common risk factor for developing chronic pulmonary aspergillosis (CPA). However, the prevalence and incidence of CPA in PTLA patients in India remain unknown. OBJECTIVES: We aimed to ascertain the incidence and prevalence of CPA in subjects with PTLA. METHODS: We identified a cohort of pulmonary tuberculosis who completed anti-tuberculosis therapy (ATT) before November 2019 from the records of the 12 tuberculosis treatment centers attached to the national program...
March 2024: Mycoses
https://read.qxmd.com/read/38387995/association-between-statin-use-and-tuberculosis-risk-in-patients-with-bronchiectasis-a-retrospective-population-based-cohort-study-in-taiwan
#10
JOURNAL ARTICLE
Kuang-Ming Liao, Chung-Shu Lee, Yu-Cih Wu, Chin-Chung Shu, Chung-Han Ho
BACKGROUND: Chronic airway diseases have been associated with an increased risk of tuberculosis (TB); however, data in patients with bronchiectasis is limited. Statins have been shown to exhibit anti-inflammatory effects by modulating the inflammatory response. This study investigated whether statin treatment could reduce the risk of TB in patients with bronchiectasis. METHODS: We conducted a retrospective cohort study using a nationwide population database of patients with bronchiectasis who did or did not receive statin treatment...
February 22, 2024: BMJ Open Respiratory Research
https://read.qxmd.com/read/38328573/cystic-fibrosis-in-an-adolescent-a-miranda-warning-against-blaming-tb-a-case-based-scholarly-update
#11
Amanuel Yegnanew Adela, Assefa Getachew Kebede, Daniel Zewdneh, Mahlet Kifle, Adriano Basso Dias
Cystic fibrosis (CF) is a multisystem disorder that occurs as a result of autosomal recessive congenital transmission of CF transmembrane conductance regulator (CFTR) gene mutation on chromosome 7. Because it is considered a disease of the Caucasian pediatric population or due to lack of awareness, it is rarely considered in developing countries like ours. This case report presents the first case of cystic fibrosis ever reported in Ethiopia and possibly East Africa, that of a 17-year-old female diagnosed with the disease following a CT scan of her abdomen and chest...
2024: Adolescent Health, Medicine and Therapeutics
https://read.qxmd.com/read/38317417/proposed-etiotypes-for-copd-controversial-issues
#12
JOURNAL ARTICLE
Sang Hyuk Kim, Ji-Yong Moon, Kyung Hoon Min, Hyun Lee
The 2023 Global Initiative for Chronic Obstructive Lung Disease (GOLD) revised the definition of chronic obstructive pulmonary disease (COPD) to broadly include a variety of etiologies. A new taxonomy, composed of etiotypes, aims to highlight the heterogeneity in causes and pathogenesis of COPD, allowing more personalized management strategies and emphasizing the need for targeted research to understand and manage COPD better. However, controversy arises with including some diseases under the umbrella term of COPD, as their clinical presentations and treatments differ from classical COPD, which is smoking-related...
February 6, 2024: Tuberculosis and Respiratory Diseases
https://read.qxmd.com/read/38309966/-annual-review-of-bronchiectasis-research-in-2023
#13
REVIEW
L S Zhang, J Y Wang, J F Xu
This review focuses on the latest advances in bronchiectasis from October 1st, 2022 to September 30th, 2023, including the etiology, diagnosis, treatment, comorbidities, and management of bronchiectasis in order to provide a reference in clinical diagnosis and treatment, and future research of bronchiectasis for domestic peers.
February 12, 2024: Chinese Journal of Tuberculosis and Respiratory Diseases
https://read.qxmd.com/read/38309959/-standard-technical-specifications-for-methacholine-chloride-methacholine-bronchial-challenge-test-2023
#14
JOURNAL ARTICLE
(no author information available yet)
The methacholine challenge test (MCT) is a standard evaluation method of assessing airway hyperresponsiveness (AHR) and its severity, and has significant clinical value in the diagnosis and treatment of bronchial asthma. A consensus working group consisting of experts from the Pulmonary Function and Clinical Respiratory Physiology Committee of the Chinese Association of Chest Physicians, the Task Force for Pulmonary Function of the Chinese Thoracic Society, and the Pulmonary Function Group of Respiratory Branch of the Chinese Geriatric Society jointly developed this consensus...
February 12, 2024: Chinese Journal of Tuberculosis and Respiratory Diseases
https://read.qxmd.com/read/38249873/etiology-diagnostic-modalities-and-short-term-outcomes-of-hemoptysis-a-retrospective-cross-sectional-study-from-a-tertiary-care-center-in-qatar
#15
JOURNAL ARTICLE
Shakeel Ahmed, Mansoor Hameed, Mustafa Al-Tikriti, Khaled Elfert, Mousa Hussein, Mutaz Albakri, Rajvir Singh, Irfan Ul Haq, Mushtaq Ahmad, Merlin Thomas
BACKGROUND: Hemoptysis is a concerning symptom characterized by the expectoration of blood from the respiratory tract, which can range from mild to life-threatening. It can be caused by various underlying conditions. Accurate diagnosis is critical for effective management. The causes of hemoptysis can vary depending on geographic location and the population's composition. In this study, we aimed to examine the etiology, diagnostic methods, and short-term outcomes of hemoptysis in Qatar, focusing on data from Hamad General Hospital (HGH), which serves as a major tertiary care center in the country...
December 30, 2023: Journal of Thoracic Disease
https://read.qxmd.com/read/38225822/long-term-management-of-people-with-post-tuberculosis-lung-disease
#16
REVIEW
Wan Seo, Hyung Woo Kim, Ju Sang Kim, Jinsoo Min
Post-tuberculosis lung disease (PTLD) is emerging as a significant area of global interest. As the number of patients surviving tuberculosis (TB) increases, the subsequent long-term repercussions have drawn increased attention due to their profound clinical and socioeconomic impacts. A primary obstacle to its comprehensive study has been its marked heterogeneity. The disease presents a spectrum of clinical manifestations which encompass tracheobronchial stenosis, bronchiectasis, granulomas with fibrosis, cavitation with associated aspergillosis, chronic pleural diseases, and small airway diseases-all persistent consequences of PTLD...
January 2024: Korean Journal of Internal Medicine
https://read.qxmd.com/read/38225554/shorter-antitubercular-therapy-for-extrapulmonary-tuberculosis-a-case-report
#17
JOURNAL ARTICLE
Diviya Bharathi Ravikumar, Barath Prashanth Sivasubramanian, Ankur Singla, Rakshaya Venu, Saketh Palasamudram Shekar
INTRODUCTION: Extrapulmonary tuberculosis (EPTB) adds to India's significant economic burden, with pericardial effusion being a potentially fatal complication. This case report highlights the need for early diagnosis and the feasibility of shorter-duration treatment for EPTB in developing countries. PRESENTATION: This case report describes a 19-year-old male from Southeast Asia who had a history of bronchiectasis involving the left lower lobe and the right middle lobe, which was cystic in nature, as well as multiple episodes of non-tuberculous pneumonia...
January 15, 2024: BMC Infectious Diseases
https://read.qxmd.com/read/38186818/subacute-invasive-pulmonary-aspergillosis-in-a-nondiabetic-immunocompetent-female-suffering-from-allergic-broncho-pulmonary-aspergillosis
#18
Subodh Kumar, Devesh Pratap Singh, Sana Ansari, Vivek Hada
A 55-year-old female presented with recent exacerbation of the chronic cough, dyspnea, and copious expectoration. The symptoms worsened during the winter months. In the past, she was misdiagnosed with pulmonary tuberculosis. A computed tomography scan revealed bronchiectasis changes, high attenuated mucus, and hypereosinophilia. The diagnosis of Allergic Bronchopulmonary Aspergillosis (ABPA) with subacute invasion was confirmed through bronchoscopy and fungal culture. Treatment with oral voriconazole significantly improved lung function and quality of life...
November 2023: Journal of Family Medicine and Primary Care
https://read.qxmd.com/read/38138876/which-is-the-best-way-to-treat-massive-hemoptysis-a-systematic-review-and-meta-analysis-of-observational-studies
#19
REVIEW
Eleni Karlafti, Dimitrios Tsavdaris, Evangelia Kotzakioulafi, Leonidas Kougias, Georgios Tagarakis, Georgia Kaiafa, Smaro Netta, Christos Savopoulos, Antonios Michalopoulos, Daniel Paramythiotis
INTRODUCTION: Hemoptysis is one of the most common symptoms of respiratory system diseases. Common causes include bronchiectasis, tumors, tuberculosis, aspergilloma, and cystic fibrosis. The severity of hemoptysis varies from mild to moderate to massive hemoptysis and can easily lead to hemodynamic instability and death from suffocation or shock. Nevertheless, the most threatening hemoptysis that is presented to the emergency department and requires hospitalization is the massive one...
November 26, 2023: Journal of Personalized Medicine
https://read.qxmd.com/read/38115299/changes-in-the-airway-microbiome-in-patients-with-bronchiectasis
#20
JOURNAL ARTICLE
Dongmei Lu, Chenxi Li, Zhiwei Zhong, Maidina Abudouaini, Aynazar Amar, Hongtao Wu, Xuemei Wei
This study used metagenomic next-generation sequencing (mNGS) technology to explore the changes of the microbial characteristics in the lower respiratory tract in patients with acute exacerbations of bronchiectasis (noncystic fibrosis) to guide clinical treatment and improve patients' quality of life and prognosis. This prospective study included 54 patients with acute exacerbation and 46 clinically stable patients admitted to the Respiratory and Critical Care Medicine Center of the People's Hospital of Xinjiang Uygur Autonomous Region from January 2020 to July 2022...
December 15, 2023: Medicine (Baltimore)
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