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Keywords Chronic stimulant use in adult...

Chronic stimulant use in adults with adhd

https://read.qxmd.com/read/37966364/growth-trajectories-in-stimulant-treated-children-and-adolescents-a-qualitative-review-of-the-literature-from-comprehensive-datasets-and-registries
#1
REVIEW
Chloe Hutt Vater, Joseph Biederman, Maura DiSalvo, Hannah O'Connor, Haley Parker, K Yvonne Woodworth, Janet Wozniak, Stephen V Faraone
Objective: Attention-deficit/hyperactivity disorder (ADHD) treatment with stimulant products has been shown to be safe and effective; however, there are remaining concerns about their possible adverse effects on growth trajectories. We conducted a systematic review of the extant literature derived from ecologically valid databases and registries to assess the body of knowledge about the effects of stimulants on growth trajectories in naturalistic samples. Methods: Using PubMed and PsycINFO, we searched for articles published before February 8, 2023 that focused on growth findings associated with stimulant treatment in pediatric ADHD from comprehensive datasets derived from naturalistic population studies...
November 2023: Journal of Child and Adolescent Psychopharmacology
https://read.qxmd.com/read/37884027/medical-cannabis-legalization-no-contribution-to-rising-stimulant-rates-in-the-usa
#2
JOURNAL ARTICLE
Garrett D Alexander, Luke R Cavanah, Jessica L Goldhirsh, Leighton Y Huey, Brian J Piper
INTRODUCTION: There has been a pronounced increase in the use of Schedule II stimulants to treat attention-deficit hyperactivity disorder (ADHD) in the United States over the last two decades. Interestingly, chronic medical cannabis (MC) use can present with cognitive impairments that resemble ADHD symptoms. This study aimed to determine if MC legalization increased prescription stimulant distribution. METHODS: Information on the distribution of methylphenidate, amphetamine, and lisdexamfetamine for 2006 to 2021 was extracted from the Drug Enforcement Administration's comprehensive database and the three-year population-corrected slopes of stimulant distribution before and after MC program implementation were compared...
October 26, 2023: Pharmacopsychiatry
https://read.qxmd.com/read/37878798/recommendation-for%C3%A2-long-term-management-of%C3%A2-adult-attention-deficit-hyperactivity-disorder-in%C3%A2-military-populations-veterans-and%C3%A2-dependents-a-narrative-review
#3
JOURNAL ARTICLE
Derek J Baughman, Crista M Watson, Jonathan W Beich, May N Joresa Herboso, Liana K Cuttie, Ari-Beth C Marlyne
INTRODUCTION: In addition to the higher burden of mental health disease in the military, there is a compounding antecedent association between behavioral health comorbidities and the treatment of attention-deficit/hyperactivity disorder (ADHD) in this population. Despite the low prevalence of new-onset ADHD in adults globally, the rate of stimulant (i.e., amphetamines) prescription is increasing. Stimulants can exacerbate mental health disease (often masquerading as ADHD symptomatology), precluding optimal treatment of the underlying etiology and imposing unnecessary dangerous side effects...
October 25, 2023: Military Medicine
https://read.qxmd.com/read/37386203/prevalence-of-chronic-and-multisite-pain-in-adolescents-and-young-adults-with-adhd-a-comparative-study-between-clinical-and-general-population-samples-the-hunt-study
#4
JOURNAL ARTICLE
Ingunn Mundal, Jorun Schei, Stian Lydersen, Per Hove Thomsen, Torunn Stene Nøvik, Levi R Kvitland
Attention-deficit/hyperactivity disorder (ADHD) and chronic pain are prevalent and associated. We examined the prevalence and distribution of chronic pain in adolescents and young adults with ADHD using 9-years longitudinal data (from T1:2009-2011 to T3:2018-2019) with three time points from a clinical health survey compared to two age-matched reference population-based samples. Mixed-effect logistic regression and binary linear regression were used to estimate the probability for chronic and multisite pain at each time point and to compare the prevalence of chronic pain with the reference populations...
June 29, 2023: European Child & Adolescent Psychiatry
https://read.qxmd.com/read/37288998/methylphenidate-use-and-restorative-treatment-needs-in-young-adults-with-attention-deficit-hyperactivity-disorder
#5
JOURNAL ARTICLE
Haggai Schermann, Nathan Schiffmann, Ran Ankory, Amir Shlaifer, Nirit Yavnai, Victoria Yoffe, Lena Natapov
OBJECTIVE: To assess the effect and dose-response of methylphenidate (MP) use on the restorative treatment needs in young adults with attention deficit hyperactivity disorder. PARTICIPANTS AND METHODS: This retrospective study comprises a cohort of military recruits aged 18-25 who served for 12 to 48 months between 2005 and 2017. The medical records of 213 604 participants were assessed of which: 6875 participants with ADHD who received treatment with MP, 6729 participants with ADHD who had no prescriptions for MP, and 200 000 healthy participants...
June 8, 2023: Special Care in Dentistry
https://read.qxmd.com/read/37176536/challenges-of-treating-adhd-with-comorbid-substance-use-disorder-considerations-for-the-clinician
#6
REVIEW
Margherita Barbuti, Marco Maiello, Vincenza Spera, Alessandro Pallucchini, Giulio E Brancati, Angelo G I Maremmani, Giulio Perugi, Icro Maremmani
Adults with attention deficit/hyperactivity disorder (ADHD) often present psychiatric comorbidities and, in particular, substance use disorder (SUD). ADHD-SUD comorbidity is characterized by greater severity of both disorders, earlier age of onset, higher likelihood of polydrug-abuse and suicidal behaviors, more hospitalizations, and lower treatment adherence. At the present stage, research focused on the pharmacological management of ADHD with comorbid SUD in both adolescents and adults is still lacking. Furthermore, while the short-term effects of stimulants are well studied, less is known about the chronic effects of these drugs on dopamine signaling...
April 24, 2023: Journal of Clinical Medicine
https://read.qxmd.com/read/37127834/effects-of-chronic-methamphetamine-exposure-on-rewarding-behavior-and-neurodegeneration-markers-in-adult-mice
#7
JOURNAL ARTICLE
Delaney L Davis, Daniel B Metzger, Philip H Vann, Jessica M Wong, Ritu A Shetty, Michael J Forster, Nathalie Sumien
Recreational and medical use of stimulants among young adults have gained popularity in the United States over the last decade and their use may increase vulnerability to brain biochemical changes and addictive behaviors. The long-term effects of chronic stimulant exposure in later adulthood have not been fully elucidated.Our study investigated whether chronic exposure to methamphetamine (METH), at a dose designed to emulate human therapeutic dosing for ADHD, would promote biochemical alterations and affect sensitivity to the rewarding effects of subsequent METH dosing...
May 2, 2023: Psychopharmacology
https://read.qxmd.com/read/36970292/case-report-methylphenidate-improved-chronic-pain-in-an-adult-patient-with-attention-deficit-hyperactivity-disorder
#8
Ekachaeryanti Zain, Atsunori Sugimoto, Jun Egawa, Toshiyuki Someya
INTRODUCTION: Chronic pain remains a health problem that is difficult to treat adequately. Its unknown cause and complex comorbidity with other illnesses, including mental disorders, amplify the severity of symptoms, which consequently decreases the quality of life of patients long term. In our clinical practice, we coincidentally found evidence that methylphenidate (MPH) effectively managed chronic pain in an adult patient with attention deficit hyperactivity disorder (ADHD). The effectiveness of MPH in the treatment of ADHD is well-established; however, its utility in treating pain remains unclear...
2023: Frontiers in Psychiatry
https://read.qxmd.com/read/36193720/effect-of-stimulants-on-final-adult-height
#9
REVIEW
Natalia M Wojnowski, Elaine Zhou, Youn Hee Jee
OBJECTIVES: The use of stimulant medications for treatment of ADHD has raised concern as to whether they adversely impact linear growth. Previous studies have indicated that stimulant medications may suppress growth for a short period after treatment initiation; however, more information is needed to evaluate the long-term effects on final adult stature. This mini review aims to evaluate the effect of stimulant medications on final adult height in children with ADHD. CONTENT: We performed a literature review across PubMed/MEDLINE database...
October 5, 2022: Journal of Pediatric Endocrinology & Metabolism: JPEM
https://read.qxmd.com/read/36168642/viloxazine-for-the-treatment-of-attention-deficit-hyperactivity-disorder
#10
JOURNAL ARTICLE
Christopher L Robinson, Katelyn Parker, Saurabh Kataria, Evan Downs, Rajesh Supra, Alan D Kaye, Omar Viswanath, Ivan Urits
PURPOSE OF REVIEW: Attention deficit hyperactivity disorder (ADHD) is a widely diagnosed neurodevelopmental disorder giving rise to symptoms of hyperactivity, impulsivity, and inattentiveness that can impair daily functioning. Stimulants, such as methylphenidate and amphetamines, are the mainstay of treatment for ADHD. However, nonstimulant drugs such as viloxazine, atomoxetine, guanfacine, and clonidine are becoming more popular due to minimal adverse effects when compared to stimulants...
2022: Health Psychology Research
https://read.qxmd.com/read/36037842/pre-clinical-evidence-that-methylphenidate-increases-motivation-and-or-reward-preference-to-search-for-high-value-rewards
#11
JOURNAL ARTICLE
Laura N Pulido, Jose A Pochapski, Adam Sugi, Julie Y Esaki, Joao L Stresser, William N Sanchez, Gabriel Baltazar, David Levcik, Romulo Fuentes, Claudio Da Cunha
Methylphenidate is a stimulant used to treat attention deficit and hyperactivity disorder (ADHD). In the last decade, illicit use of methylphenidate has increased among healthy young adults, who consume the drug under the assumption that it will improve cognitive performance. However, the studies that aimed to assess the methylphenidate effects on memory are not consistent. Here, we tested whether the effect of methylphenidate on a spatial memory task can be explained as a motivational and/or a reward effect...
February 2, 2023: Behavioural Brain Research
https://read.qxmd.com/read/34933573/glycemic-control-and-diabetes-related-complications-in-adults-with-type-1-diabetes-mellitus-and-adhd
#12
JOURNAL ARTICLE
Michal Vinker-Shuster, Roy Eldor, Ilan Green, Avivit Golan-Cohen, Iris Manor, Eugene Merzon
OBJECTIVE: To assess the correlation of co-morbid ADHD and diabetes-related complications in patients with type-1-diabetes-mellitus (T1DM). METHODS: A retrospective cross-sectional study was conducted during 2018 using the Leumit-Health-Services(LHS) database. Diabetes-related complications were assessed in patients with T1DM and ADHD (T1DM-ADHD+) and compared with patients with T1DM alone (T1DM-ADHD-). RESULTS: Out of 789 adult-patients with T1DM, 75 (9...
December 21, 2021: Journal of Attention Disorders
https://read.qxmd.com/read/33179887/adhd-in-children-common-questions-and-answers
#13
JOURNAL ARTICLE
Jennifer G Chang, Francesca M Cimino, Weyinshet Gossa
Attention-deficit/hyperactivity disorder (ADHD) is a multidimensional chronic neurodevelopmental condition that affects 8.4% of U.S. children between two and 17 years of age and may pose long-term morbidity if untreated. The evaluation for ADHD begins when parents or caregivers present to primary care physicians with concerns about behavior problems or poor school or social function. A comprehensive history and physical examination should assess for comorbid or other conditions that can mimic ADHD. The combination of Diagnostic and Statistical Manual of Mental Disorders, 5th ed...
November 15, 2020: American Family Physician
https://read.qxmd.com/read/31644379/home-induction-and-outpatient-treatment-of-kratom-use-disorder-with-buprenorphine-naloxone-a-case-report-in-a-young-adult
#14
JOURNAL ARTICLE
Kelsey K Schmuhl, Spencer M Gardner, Casey B Cottrill, Andrea E Bonny
Background : The use of the natural product, kratom, has increased significantly in recent years. The active compounds in kratom have been shown to produce both opioid and stimulant-like effects. While kratom is marketed as a safe, non-addictive method to treat pain and opioid withdrawal, there have been reports demonstrating that kratom is physiologically addictive and linked to overdose deaths. A limited number of case-reports are available describing treatment of kratom use disorder in middle-aged adults, generally in the context of chronic pain and in inpatient settings...
2020: Substance Abuse
https://read.qxmd.com/read/30776284/-transition-of-adolescents-with-attention-deficit-hyperactivity-disorder-implications-for-treatment-of-adults
#15
JOURNAL ARTICLE
José Martínez-Raga, María López-Cerveró
Attention deficit hyperactivity disorder (ADHD) is a chronic, complex and multifactorial neurodevelopmental disorder associated with high rates of concurrent psychiatric disorders, along with problems and complications on different areas of individual functioning. ADHD is not exclusively a childhood disorder, 40-60% persisting into adulthood with an estimated prevalence of 2.5-5%. Adolescence is a stage where great and continuous changes occur, associated with a lower adherence to treatment, a greater vulnerability to the emergence of academic problems, more risk-behaviors, the onset of substance use and higher rates of other comorbid disorders...
2019: Medicina
https://read.qxmd.com/read/30646105/prevalence-of-and-factors-associated-with-long-term-concurrent-use-of-stimulants-and-opioids-among-adults-with-attention-deficit-hyperactivity-disorder
#16
JOURNAL ARTICLE
Yu-Jung Jenny Wei, Yanmin Zhu, Wei Liu, Regina Bussing, Almut G Winterstein
Importance: There exist limited data on the long-term concurrent use of stimulants and opioids among adults with attention-deficit/hyperactivity disorder (ADHD), a population at risk for prescription drug abuse. Objective: To assess the prevalence and secular trends of and the factors associated with long-term concurrent use of stimulants and opioids among adults with ADHD. Design, Setting, and Participants: This cross-sectional study assessed Medicaid Analytic eXtract data from 29 states between 1999 and 2010...
August 3, 2018: JAMA Network Open
https://read.qxmd.com/read/30557579/exposure-to-methylphenidate-in-adolescence-and-adulthood-modulates-cross-sensitization-to-amphetamine-in-adulthood-in-three-genetically-variant-female-rat-strains
#17
JOURNAL ARTICLE
Natasha Kharas, Pamela Yang, Daniel Castro-Alvarado, Kevelyn Rose, Nachum Dafny
Attention Deficit Hyperactivity Disorder (ADHD) is a developmental, behavioral disorder that is characterized by patterns of impulsivity and limited attention. Stimulants, such as methylphenidate (MPD) and amphetamine (Amph), are utilized as first-line agents in the treatment of ADHD. While Amph is known to elicit dependence, MPD is not. Interdependence between MPD and Amph is a growing concern. Therefore, it is important to explore this interaction in animal models to gain insight on its mechanisms. In experimental studies, drugs that elicit behavioral sensitization and cross-sensitization in animals are considered to have the potential to elicit dependence...
April 19, 2019: Behavioural Brain Research
https://read.qxmd.com/read/29503545/treatment-patterns-health-care-resource-utilization-and-costs-in-japanese-adults-with-attention-deficit-hyperactivity-disorder-treated-with-atomoxetine
#18
JOURNAL ARTICLE
Hideyuki Imagawa, Saurabh P Nagar, William Montgomery, Tomomi Nakamura, Masayo Sato, Keith L Davis
OBJECTIVE: To describe the characteristics and medication treatment patterns of adult patients with attention-deficit/hyperactivity disorder (ADHD) prescribed atomoxetine in Japan. MATERIALS AND METHODS: A retrospective analysis of insurance claims data was conducted using the Japan Medical Data Center database. Adults (≥18 years) with ADHD who had ≥1 atomoxetine claim from January 1, 2013 to December 31, 2014, and ≥180 to ≤900 days of follow-up were included...
2018: Neuropsychiatric Disease and Treatment
https://read.qxmd.com/read/29397534/chronic-methylphenidate-alters-tonic-and-phasic-glutamate-signaling-in-the-frontal-cortex-of-a-freely-moving-rat-model-of-adhd
#19
JOURNAL ARTICLE
Erin M Miller, Jorge E Quintero, Francois Pomerleau, Peter Huettl, Greg A Gerhardt, Paul E A Glaser
Glutamate dysfunction has been implicated in a number of substance of abuse studies, including cocaine and methamphetamine. Moreover, in attention-deficit/hyperactivity disorder (ADHD), it has been discovered that when the initiation of stimulant treatment occurs during adolescence, there is an increased risk of developing a substance use disorder later in life. The spontaneously hypertensive rat (SHR) serves as a phenotype for ADHD and studies have found increased cocaine self-administration in adult SHRs when treated with the stimulant methylphenidate (MPH) during adolescence...
January 2019: Neurochemical Research
https://read.qxmd.com/read/29026749/implementation-of-a-schedule-ii-patient-agreement-for-opioids-and-stimulants-in-an-adult-primary-care-practice
#20
JOURNAL ARTICLE
Erin Downey, Wei Pan, Jan Harrison, Esther Poza-Juncal, Paula Tanabe
BACKGROUND: The consumption of controlled substances in North Carolina and the nation has created a health crisis with epidemic levels of medication diversion, abuse, overdose and death. Primary care providers are the principal prescribers of controlled substances and at greatest risk of encountering patients that abuse medications. Guidelines recommend patient agreements with monitoring requirements when prescribing opioids and stimulants. Studies have focused on opioids and excluded stimulants...
January 2017: Journal of Family Medicine and Primary Care
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