Yajie Lu, Lulu Liu, Hongxing Li, Bilin Chen, Yu Gu, Li Wang, Chunlai Feng, Cheng Chen, Yanbin Chen, Wenkui Sun, Xuefan Cui, Min Cao, Yujian Tao, Jinjin Zhong, Huanhuan Zhong, Yueyan Ni, Yuchen Cai, Mengyue Song, Xiaoguang Liu, Yi Shi, Xin Su
OBJECTIVES: Aspergillus-specific IgG antibody (Asp IgG) has been successfully applied in the diagnosis of chronic pulmonary aspergillosis. We explored its value in nonneutropenic invasive pulmonary aspergillosis (IPA) by a multicenter, prospective, and controlled study. METHODS: We enrolled 372 clinically suspected nonneutropenic patients with IPA from February 2015 to August 2022. After excluding 4 cases with Aspergillus colonization, the remaining 368 cases were finally confirmed as patients with IPA (n = 99), or non-IPA patients (n = 269) consisting of community-acquired pneumonia (n = 206), tuberculosis (n = 22), nontuberculous mycobacteria (n = 5), lung abscess (n = 6), or noninfectious diseases (n = 30)...
June 2023: Clinical Microbiology and Infection