Jesús F García-Gavilán, Nancy Babio, Estefanía Toledo, Zhila Semnani-Azad, Cristina Razquin, Courtney Dennis, Amy Deik, Dolores Corella, Ramón Estruch, Emilio Ros, Montserrat Fitó, Fernando Arós, Miquel Fiol, José Lapetra, Rosa Lamuela-Raventos, Clary Clish, Miguel Ruiz-Canela, Miguel Ángel Martínez-González, Frank Hu, Jordi Salas-Salvadó, Marta Guasch-Ferré
BACKGROUND: Olive oil consumption has been inversely associated with the risk of type 2 diabetes (T2D) and cardiovascular disease (CVD). However, the impact of olive oil consumption on plasma metabolites remains poorly understood. This study aims to identify plasma metabolites related to total and specific types of olive oil consumption, and to assess the prospective associations of the identified multi-metabolite profiles with the risk of T2D and CVD. METHODS: The discovery population included 1837 participants at high cardiovascular risk from the PREvención con DIeta MEDiterránea (PREDIMED) trial with available metabolomics data at baseline...
December 13, 2023: Cardiovascular Diabetology