Hae Won Jung, Chang-Yeon Kim, Seung-Pyo Hong, Han-Joon Bae, Ji Yong Choi, Jae Kean Ryu, Jin-Bae Lee, Kyoung-Hoon Lee, Kyoo-Rok Han, Dong-Heon Yang, Chang-Gyu Park, Gheol-Woong Yu, Moo-Yong Rhee, Sung-Ji Park, Min-Su Hyon, Joon-Han Shin, Bum-Kee Hong, Han-Young Jin, Sung-Yun Lee, Sang-Hoon Seol, Sang-Rok Lee, Song-Yi Kim, Kwang-Je Lee, Eun-Joo Cho, Chang-Wook Nam, Tae-Ho Park, Ung Kim, Kee-Sik Kim
The authors performed this study to investigate the efficacy and safety of a rosuvastatin (RSV)/amlodipine (AML) polypill compared with those of atorvastatin (ATV)/AML polypill. We included 259 patients from 21 institutions in Korea. Patients were randomly assigned to 1 of 3 treatment groups: RSV 10 mg/AML 5 mg, RSV 20 mg/AML 5 mg, or ATV 20 mg /AML 5 mg. The primary endpoint was the efficacy of the RSV 10.20 mg/AML 5 mg via percentage changes in LDL-C after 8 weeks of treatment, compared with the ATV 20 mg /AML 5 mg...
August 16, 2023: Journal of Clinical Hypertension