Yoshitomo Morinaga, Hiromichi Suzuki, Shigeyuki Notake, Takashi Mizusaka, Keiichi Uemura, Shinobu Otomo, Yuka Oi, Akihito Ushiki, Naoki Kawabata, Kazuaki Kameyama, Eri Morishita, Yoshiko Uekura, Akio Sugiyama, Yosuke Kawashima, Katsunori Yanagihara
Introduction. Resistance against macrolide antibiotics in Mycoplasma pneumoniae is becoming non-negligible in terms of both appropriate therapy and diagnostic stewardship. Molecular methods have attractive features for the identification of Mycoplasma pneumoniae as well as its resistance-associated mutations of 23S ribosomal RNA (rRNA). Hypothesis/Gap Statement. The automated molecular diagnostic sytem can identify macrolide-resistant M. pneumoniae . Aim. To assess the performance of an automated molecular diagnostic system, GENECUBE Mycoplasma, in the detection of macrolide resistance-associated mutations...
November 3, 2020: Journal of Medical Microbiology