keyword
https://read.qxmd.com/read/38391272/morphological-evidence-of-a-potential-arrhythmogenic-substrate-in-the-caudal-and-cranial-vena-cava-in-horses
#1
JOURNAL ARTICLE
Lara Ibrahim, Eva Buschmann, Gunther van Loon, Pieter Cornillie
BACKGROUND: Three-dimensional electro-anatomical mapping, previously performed in horses with atrial arrhythmias, has demonstrated the medial region of the caudal vena cava (CaVC), 1-8 cm caudal to the fossa ovalis, as an anatomical predilection site for atrial tachycardia associated with areas of slow conduction and conduction block. Slow conduction has also been recorded in the cranial vena cava (CrVC). OBJECTIVES: To investigate the morphological characteristics of the myocardial sleeves (MS) in the CaVC and CrVC, in order to identify a potential substrate of right sided atrial arrhythmias...
February 23, 2024: Equine Veterinary Journal
https://read.qxmd.com/read/38310341/association-of-tetralogy-of-fallot-and-complete-atrioventricular-canal-a-single-center-40-year-experience
#2
JOURNAL ARTICLE
Alejandro Fernandez-Cisneros, Steven J Staffa, Sitaram M Emani, Mariana Chávez, Kevin G Friedman, David M Hoganson, Aditya K Kaza, Pedro J Del Nido, Christopher Baird
OBJECTIVES: Outcome data in tetralogy of Fallot (ToF) and complete atrioventricular canal (CAVC) are limited. We report our experience for over 40 years in this patient population. METHODS: Single center, retrospective analysis of patients who underwent surgical repair with diagnosis of ToF-CAVC from 1979 to 2022, divided in two different periods and compared. RESULTS: A total of 116 patients were included: 1979-2007 (n = 61) and 2008-2021 (n = 55)...
February 3, 2024: European Journal of Cardio-thoracic Surgery
https://read.qxmd.com/read/37692634/complete-atrioventricular-canal-defect-in-a-non-syndromic-adult-patient-an-unusual-presentation
#3
Elias M Nabhan, Samih B Khoury, Tony E Bechara
This case report presents a 30-year-old male patient with a history of autism spectrum disorder who experienced a drastic decline in physical activity in recent years. Upon examination, the patient was found to be relatively bedridden, lethargic, and unable to maintain an upright gait, accompanied by severe clubbing. Transthoracic echocardiography revealed a massive 4 cm complete atrioventricular canal (CAVC) defect. Although the patient was asymptomatic throughout most of his life, the CAVC defect appeared to have progressively impacted his health and activity tolerance...
August 2023: Curēus
https://read.qxmd.com/read/36721320/outcomes-after-repair-of-complete-atrioventricular-canal-with-a-modified-single-patch-technique-a-retrospective-study
#4
JOURNAL ARTICLE
George Samanidis, Konstantinos Kostopanagiotou, Meletios Kanakis, Georgios Kourelis, Kyriaki Kolovou, Georgios Vagenakis, Dimitrios Bobos, Nicholas Giannopoulos
BACKGROUND: This study aimed to present the short- and midterm outcomes after complete atrioventricular canal defect (CAVC) repair using a single-patch technique. METHODS: This study included 30 children who underwent surgical correction of the CAVC using a single-patch technique. RESULTS: The median age of the patients was 5.7 months (interquartile range [IQR], 5.0-7.5 months), and 23 patients (76.7%) had type A CAVC. Fourteen patients (46...
February 1, 2023: J Yeungnam Med Sci
https://read.qxmd.com/read/35979598/surgical-repair-of-complete-common-atrioventricular-canal-in-a-conjoined-twin-following-separation
#5
JOURNAL ARTICLE
Stephen H Fatuzzo, Jason W Greenberg, Russel Hirsch, Ilias D Iliopoulos, Michael D Taylor, David L S Morales
Congenital heart disease (CHD) is common in conjoined twins but reports of surgical repair in this population are rare. We present the case of a conjoined twin diagnosed prenatally with a complete common atrioventricular canal defect (CAVC). Due to wound complications from twin separation, definitive repair was deferred and pulmonary arterial banding was performed initially. At 6 months, a complete CAVC repair was performed. The present case adds to the literature on successful cardiac surgical repairs in conjoined twins...
August 17, 2022: World Journal for Pediatric & Congenital Heart Surgery
https://read.qxmd.com/read/35537615/visualization-and-quantification-of-the-unrepaired-complete-atrioventricular-canal-valve-using-open-source-software
#6
JOURNAL ARTICLE
Hannah H Nam, Christian Herz, Andras Lasso, Alana Cianciulli, Maura Flynn, Jing Huang, Zi Wang, Beatriz Paniagua, Jared Vicory, Saleha Kabir, John Simpson, David Harrild, Gerald Marx, Meryl S Cohen, Andrew C Glatz, Matthew A Jolley
BACKGROUND: Repair of complete atrioventricular canal (CAVC) is often complicated by residual left atrioventricular valve regurgitation. The structure of the mitral and tricuspid valves in biventricular hearts has previously been shown to be associated with valve dysfunction. However, the three-dimensional (3D) structure of the entire unrepaired CAVC valve has not been quantified. Understanding the 3D structure of the CAVC may inform optimized repair. METHODS: Novel open-source work flows were created in SlicerHeart for the modeling and quantification of CAVC valves on the basis of 3D echocardiographic images...
September 2022: Journal of the American Society of Echocardiography
https://read.qxmd.com/read/35403044/intraoperative-conduction-mapping-in-complex-congenital-heart-surgery
#7
JOURNAL ARTICLE
Eric N Feins, Edward T O'Leary, David M Hoganson, Noah Schulz, Emily Eickoff, Jocelyn Davee, John K Triedman, Christopher W Baird, Pedro J Del Nido, Sitaram Emani, Elizabeth S DeWitt
Objective: Postoperative heart block is a significant problem in congenital heart surgery because of the unpredictability and variability of conduction tissue location in complex congenital heart defects. A novel technique for intraoperative conduction system mapping during complex congenital heart surgery is described. Methods: Intraoperative conduction system mapping was performed utilizing a high-density multielectrode grid catheter to collect intracardiac electrograms on open, beating hearts during repair of complex congenital heart defects...
April 2022: JTCVS techniques
https://read.qxmd.com/read/34627233/copy-number-variation-analysis-in-chinese-children-with-complete-atrioventricular-canal-and-single-ventricle
#8
JOURNAL ARTICLE
Xingyu Zhang, Bo Wang, Guoling You, Ying Xiang, Qihua Fu, Yongguo Yu, Xiaoqing Zhang
BACKGROUND: Congenital heart disease (CHD) is one of the most common birth defects. Copy number variations (CNVs) have been proved to be important genetic factors that contribute to CHD. Here we screened genome-wide CNVs in Chinese children with complete atrioventricular canal (CAVC) and single ventricle (SV), since there were scarce researches dedicated to these two types of CHD. METHODS: We screened CNVs in 262 sporadic CAVC cases and 259 sporadic SV cases respectively, using a customized SNP array...
October 9, 2021: BMC Medical Genomics
https://read.qxmd.com/read/34526241/dosing-of-opioid-medications-during-and-after-pediatric-cardiac-surgery-for-children-with-down-syndrome
#9
JOURNAL ARTICLE
Elizabeth R Vogel, Steven J Staffa, James A DiNardo, Morgan L Brown
OBJECTIVE: To determine whether children with Down syndrome (DS) receive higher doses of opioid medications compared with children without DS for repair of complete atrioventricular canal (CAVC). DESIGN: A retrospective chart review of children with and without DS who underwent primary repair of CAVC. The exclusion criteria included unbalanced CAVC and patients undergoing biventricular staging procedures. The primary outcome was oral morphine equivalents (OME) received in the first 24 hours after surgery...
January 2022: Journal of Cardiothoracic and Vascular Anesthesia
https://read.qxmd.com/read/34350818/the-effect-of-surgical-technique-age-and-trisomy-21-on-early-outcome-of-surgical-management-of-complete-atrioventricular-canal-defect
#10
JOURNAL ARTICLE
Sherief Azzab, Ahmed Samy, Hamdy Singab, Mohamed Zeinah, Gledisa Musollari, Ariana Axiaq, Amer Harky, Ahmed Tarek, Mohamed El Ghanam
BACKGROUND: The optimal timing, surgical technique, and the influence of Trisomy 21 on the outcome of surgical repair of Complete Atrioventricular Canal Defect remains uncertain. We reviewed our experience in the repair of CAVC to identify the influence of these factors on operative outcomes. METHODS: A prospective study included 70 patients, who underwent repair of CAVC at our institute between July, 2016 and October, 2019. Primary endpoint was mortality and the secondary endpoint was a degree of left atrioventricular valve regurgitation...
August 5, 2021: Cardiology in the Young
https://read.qxmd.com/read/34023203/the-characterization-of-postoperative-mechanical-respiratory-requirement-in-neonates-and-infants-undergoing-cardiac-surgery-on-cardiopulmonary-bypass-in-a-single-tertiary-institution
#11
JOURNAL ARTICLE
Sophia Koutsogiannaki, Sheng Xiang Huang, Karina Lukovits, Samuel Kim, Rachel Bernier, Kirsten C Odegard, Koichi Yuki
OBJECTIVES: Although neonates and infants undergoing cardiac surgery on cardiopulmonary bypass (CPB) are at high risk of developing perioperative morbidity and mortality, including lung injury, the intraoperative profile of lung injury in this cohort is not well-described. Given that the postoperative course of patients in the pediatric cardiac surgical arena has become increasingly expedited, the objective of this study was to characterize the profiles of postoperative mechanical ventilatory support in neonates and infants undergoing cardiac surgery on CPB and to examine the characteristics of lung mechanics and lung injury in this patient population who are potentially amendable to early postoperative recovery in a single tertiary pediatric institution...
January 2022: Journal of Cardiothoracic and Vascular Anesthesia
https://read.qxmd.com/read/33759429/long-term-trends-in-the-prevalence-of-congenital-heart-defects-in-patients-with-down-syndrome-in-southern-poland
#12
JOURNAL ARTICLE
Artur Dobosz, Mirosław Bik-Multanowski
INTRODUCTION: Down syndrome is one of the most common chromosomal abnormalities in humans. Patients have typical dysmorphic features and various congenital malformations. Congenital heart defects were reported as the most common of the latter, occurring in approximately 50% of the cases. THE AIM: We aimed to analyse the long-term trends in the prevalence of Down syndrome and related heart defects in the population of southern Poland (Krakow region). MATERIAL AND METHODS: We analysed 500 consecutive patients with Down syndrome who were born from 2006 through 2017 and were diagnosed at the Department of Medical Genetics, Jagiellonian University...
January 29, 2021: Journal of mother and child
https://read.qxmd.com/read/33578785/clinical-syndromic-phenotypes-and-the-potential-role-of-genetics-in-pulmonary-vein-stenosis
#13
JOURNAL ARTICLE
Abbas H Zaidi, Jessica M Yamada, David T Miller, Kerry McEnaney, Christina Ireland, Amy E Roberts, Kimberlee Gauvreau, Kathy J Jenkins, Ming Hui Chen
Pulmonary vein stenosis (PVS) is a rare, frequently lethal disease with heterogeneous phenotypes and an unclear etiology. Limited studies have reported associations between PVS and congenital heart disease (CHD), chronic lung disease (CLD), and/or prematurity; however, to date, there have been no studies that report detailed clinical syndromic phenotypes and the potential role of genetics in PVS. An existing registry of multivessel PVS patients seen at Boston Children's Hospital (BCH) was queried between August 2006 and January 2017 for all existing genetic testing data on these patients...
February 10, 2021: Children
https://read.qxmd.com/read/33359720/dynamic-annular-modeling-of-the-unrepaired-complete-atrioventricular-canal-annulus
#14
JOURNAL ARTICLE
Hannah H Nam, Patrick V Dinh, Andras Lasso, Christian Herz, Jing Huang, Adriana Posada, Ahmed H Aly, Alison M Pouch, Saleha Kabir, John Simpson, Andrew C Glatz, David M Harrild, Gerald Marx, Gabor Fichtinger, Meryl S Cohen, Matthew A Jolley
BACKGROUND: Repair of complete atrioventricular canal (CAVC) is often complicated by atrioventricular valve regurgitation, particularly of the left-sided valve. Understanding the 3-dimensional (3D) structure of the atrioventricular canal annulus before repair may help to inform optimized repair. However, the 3D shape and movement of the CAVC annulus has been neither quantified nor rigorously compared with a normal mitral valve annulus. METHODS: The complete annuli of 43 patients with CAVC were modeled in 4 cardiac phases using transthoracic 3D echocardiograms and custom code...
February 2022: Annals of Thoracic Surgery
https://read.qxmd.com/read/33000608/prevalence-of-elevated-pulmonary-artery-systolic-pressure-in-down-syndrome-young-patients-with-and-without-congenital-heart-disease
#15
JOURNAL ARTICLE
A Nicoletti, M Vatrano, S Sestito, R Apa, S Patroniti, G Ceravolo, M P Calabrò, F Parisi, K Roppa, R De Sarro, E Gitto, L Pensabene, D Concolino
This study examined the prevalence and distribution of elevated systolic pulmonary arterial pressure, measured by echocardiography, in young patients with down syndrome associated or not with congenital heart disease and surgical correction during childhood. Pulmonary artery systolic pressure, computed by regurgitant tricuspid flow velocity evaluation, is the most frequently used parameter for the screening of pulmonary hypertension. Down syndrome and congenital heart disease often coexist and the probability to detect elevated systolic pulmonary arterial pressure in this setting is high...
2020: Journal of Biological Regulators and Homeostatic Agents
https://read.qxmd.com/read/31654997/long-term-trends-in-the-prevalence-of-congenital-heart-defects-in-patients-with-down-syndrome-in-southern-poland
#16
JOURNAL ARTICLE
Artur Dobosz, Mirosław Bik-Multanowski
OBJECTIVE: Introduction: Down syndrome is one of the most common chromosomal abnormalities in humans. Patients have typical dysmorphic features and various congenital malformations. Congenital heart defects were reported as the most common of the latter, occurring in approximately 50% of the cases. The aim: We aimed to analyse the long-term trends in the prevalence of Down syndrome and related heart defects in the population of southern Poland (Krakow region). PATIENTS AND METHODS: Material and methods: We analysed 500 consecutive patients with Down syndrome who were born from 2006 through 2017 and were diagnosed at the Department of Medical Genetics, Jagiellonian University...
2019: Developmental Period Medicine
https://read.qxmd.com/read/31597616/repair-of-double-outlet-right-ventricle-midterm-outcomes
#17
JOURNAL ARTICLE
Olubunmi Oladunjoye, Breanna Piekarski, Christopher Baird, Puja Banka, Gerald Marx, Pedro J Del Nido, Sitaram M Emani
OBJECTIVE: Double outlet right ventricle (DORV) is a complex cardiac malformation with many anatomic variations and various approaches for surgical repair. This study aimed to describe the clinical outcomes of biventricular (BiV) repair for DORV. METHODS: Patients with DORV, who underwent BiV repair between January 2000 and December 2017 were retrospectively reviewed. Group 1 underwent primary BiV repair, whereas group 2 underwent staged BiV repair over a series of operations...
August 30, 2019: Journal of Thoracic and Cardiovascular Surgery
https://read.qxmd.com/read/31165901/characterisation-of-computed-tomography-angiography-findings-in-paediatric-patients-with-heterotaxy
#18
JOURNAL ARTICLE
Carlos F Ugas Charcape, Larry R Alpaca Rodriguez, Irma A Matos Rojas, Claudia I Lazarte Rantes, Melissa Valdez Quintana, Doris A Katekaru Tokeshi, Monica Epelman
BACKGROUND: Heterotaxy refers to the abnormal arrangement of organs across the left-right axis and is typically associated with complex cardiovascular malformations. OBJECTIVE: To characterise the range of cardiac and extracardiac CT angiography findings in children with heterotaxy using the latest nomenclature consensus and to compare the different types of isomerism. MATERIALS AND METHODS: We retrospectively analysed the data of 64 consecutive paediatric patients referred to our tertiary paediatric cardiovascular centre who underwent CT angiography for the evaluation of known or suspected heterotaxy within a 52-month period...
August 2019: Pediatric Radiology
https://read.qxmd.com/read/31065759/preoperative-clinical-and-echocardiographic-factors-associated-with-surgical-timing-and-outcomes-in-primary-repair-of-common-atrioventricular-canal-defect
#19
JOURNAL ARTICLE
Danielle S Burstein, Patrick E Gray, Heather M Griffis, Andrew C Glatz, Meryl S Cohen, J William Gaynor, David J Goldberg
In complete atrioventricular canal defect (CAVC), there are limited data on preoperative clinical and echocardiographic predictors of operative timing and postoperative outcomes. A retrospective, single-center analysis of all patients who underwent primary biventricular repair of CAVC between 2006 and 2015 was performed. Associated cardiac anomalies (tetralogy of Fallot, double outlet right ventricle) and arch operation were excluded. Echocardiographic findings on first postnatal echocardiogram were correlated with surgical timing and postoperative outcomes using bivariate descriptive statistics and multivariable logistic regression...
June 2019: Pediatric Cardiology
https://read.qxmd.com/read/30242970/complete-atrioventricular-canal-repair-with-a-decellularized-porcine-small-intestinal-submucosa-patch
#20
JOURNAL ARTICLE
Eliana Al Haddad, Damien J LaPar, Jeffrey Dayton, Elizabeth H Stephens, Emile Bacha
BACKGROUND: Congenital heart defects affect nearly 1% of all children born per year in the United States, and complete atrioventricular canal (CAVC) accounts for 2%-9%. While several patch materials have been used for septal defect closure during CAVC repair, clear superiority of one material over another has yet to be established. METHODS: A retrospective review of clinical outcomes following CAVC repair at Morgan Stanley Children's Hospital/Columbia University was performed on operations conducted from March 2010 to September 2017...
November 2018: Congenital Heart Disease
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