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https://read.qxmd.com/read/30732197/association-between-food-allergy-and-ankylosing-spondylitis-an-observational-study
#1
Qian Niu, Wei Wei, Zhuochun Huang, Junlong Zhang, Bin Yang, Lanlan Wang
Food allergies can alter the gut microbiome composition, increasing the risk of conditions such as ankylosing spondylitis (AS).To identify the association between specific allergens and AS, we investigated the differences in the serum levels of 14 food antigen-specific immunoglobulin (Ig) G between AS patients and healthy participants. The association between the levels of these antibodies and disease activity was assessed by measuring the inflammatory marker C-reactive protein (CRP).We enrolled 75 AS patients and 78 healthy controls who had undergone antigen-specific IgG tests in West China Hospital between January 2015 and October 2017, and performed enzyme-linked immunosorbent assays for specific IgG against 14 food allergens: rice, egg, mushroom, milk, pork, chicken, beef, crab, codfish, corn, soybean, tomato, shrimp, and wheat...
February 2019: Medicine (Baltimore)
https://read.qxmd.com/read/30597474/cross-allergenicity-of-crustacean-and-the-edible-insect-gryllus-bimaculatus-in-patients-with-shrimp-allergy
#2
Norio Kamemura, Mayumi Sugimoto, Norimasa Tamehiro, Reiko Adachi, Sayuri Tomonari, Takahito Watanabe, Taro Mito
Food scarcity is a serious problem for many developing as well as developed countries. Edible insects have attracted attention recently as a novel food source. Crickets are especially high in nutritional value and easy to breed and harvest. In this study, we evaluated the risk of allergic reactions associated with cricket consumption in individuals with crustacean allergy. We evaluated food allergy risk in the consumption of Gryllus bimaculatus (cricket) in patients with shrimp allergy, using enzyme-linked immunosorbent assay (ELISA) and IgE crosslinking-induced luciferase expression assay (EXiLE)...
December 28, 2018: Molecular Immunology
https://read.qxmd.com/read/30597268/enzyme-nanovehicles-histaminase-and-catalase-delivered-in-nanoparticulate-chitosan
#3
Mihaela Leonida, Sabrina Belbekhouche, Faith Adams, Uday Kiran Bijja, Dinesh-Amraram Choudhary, Ish Kumar
Widespread skin allergies are of high societal concern. This pathology usually includes "histamine intolerance" and inflammatory processes affecting the skin. Oxidative stress, due to both intrinsic and environmental factors, leads to skin disorders, disease, and aging. Since the stratum corneum (SC) allows only small, lipophilic molecules to be absorbed through the skin, proteins, which are large amphoteric macromolecules, display limited bioavailability. The present study investigates the potential of chitosan nanoparticles as vehicle for two enzymes (catalytic proteins): catalase (CAT) and diamine oxidase (histaminase, DAO)...
December 28, 2018: International Journal of Pharmaceutics
https://read.qxmd.com/read/30572432/high-prevalence-of-ige-sensitization-against-house-dust-mites-in-pregnant-women
#4
Chang-Ching Yeh, Keh-Gong Wu, Peng-Hui Wang
There is an increase in prevalence and financial burden of childhood atopic disorders in recent years. Understanding allergic conditions of pregnant women is important for developing strategies for prevention and management of allergy-related diseases. However, little is currently known about the atopic conditions in pregnant women.The sera from 46 pregnant women were analyzed for allergen-specific IgE antibodies using the Optigen assay and SDS-PAGE immunoblot analysis.Results from the Optigen assay showed that 20 (43%) of the 46 serum samples analyzed demonstrated IgE reactivity against mite p (Dermatophagoides pteronyssinus) (95%), mite f (D farinae) (95%), house dust (60%), cat (25%), shrimp (20%), crab (15%), cockroach (10%), dog (5%), latex (5%), willow black (5%), and timothy grass (5%)...
December 2018: Medicine (Baltimore)
https://read.qxmd.com/read/30537803/frequency-and-pattern-of-ige-mediated-sensitization-to-aero-and-food-allergens-in-ahvaz-province-of-khuzestan-in-southwestern-iran
#5
Mohammad Shahrooei, Abbas Fayezi, Raheleh Shokouhi Shoormasti, Faramarz Zakavi, Leila Golpasand Hagh, Johan Van Eldere, Xavier Bossuyt, Erna Van Hoeyveld
Efficient diagnosis of allergy and proper treatment need identification of the causative allergens eliciting clinical symptoms. The present study was performed to identify the most common aero- and food allergens and determine the pattern of sensitization among people of Ahvaz (southwestern Iran), one of the most polluted cities worldwide. Based on the physical examination and medical records, patients were referred to the Allergy laboratory for "in vitro" IgE determination. Specific and total IgE was determined by the ImmunoCAP system (Thermo Fisher-Phadia, Uppsala, Sweden)...
August 12, 2018: Iranian Journal of Allergy, Asthma, and Immunology
https://read.qxmd.com/read/30503670/self-reported-hypersensitivity-and-allergy-to-foods-amongst-mexican-adolescents-prevalence-and-associated-factors
#6
T R Bedolla-Pulido, M Bedolla-Barajas, J Morales-Romero, T I Bedolla-Pulido, M V Domínguez-García, D D Hernández-Colín, M V Flores-Merino
BACKGROUND: The prevalence of food allergy is on the rise on a global scale. OBJECTIVE: To determine the prevalence of food hypersensitivity (FHS) and probable food allergy (PFA), as well as the foods and factors associated with these occurrences. METHODS: A cross-sectional study was carried out among 1992 adolescents (aged 15-18 years). Each adolescent answered a structured questionnaire. A multivariate analysis was used to identify the association between the variables...
November 29, 2018: Allergologia et Immunopathologia
https://read.qxmd.com/read/30410550/anaphylactic-reaction-in-patient-allergic-to-mango
#7
Natalia Ukleja-Sokołowska, Ewa Gawrońska-Ukleja, Kinga Lis, Magdalena Żbikowska-Gotz, Łukasz Sokołowski, Zbigniew Bartuzi
Background: An allergy to mango is extremely rare. The antigenic composition of the fruit is not fully known. Profilin from mango has a structure similar to birch tree profiling: it is responsible for cross-reactions between mango and pear, apple, and peach. A panallergen with a structure similar to mugwort defensin (Art v 1) which cross-reacts with celery, carrot, peanuts, pepper, aniseed, and caraway has been previously described. Case study: A female patient, 30 years old, was admitted in February 2017 because of recurrent allergic reactions following consumption of various foods...
2018: Allergy, Asthma, and Clinical Immunology
https://read.qxmd.com/read/30408639/food-allergy-is-associated-with-depression-and-psychological-distress-a-web-based-study-in-11-876-japanese
#8
Shinsuke Hidese, Shun Nogawa, Kenji Saito, Hiroshi Kunugi
BACKGROUND: Although some studies suggest a possible association between food allergy (FA) and depression/psychological distress, empirical data are still scarce. We aimed to examine whether this association exists in a large sample of the Japanese population. METHODS: This web-based cross-sectional survey included 1000 individuals with self-reported lifetime history of clinical depression (mean age: 41.4 years, 501 men), and the remaining 10,876 subjects served as controls (mean age: 45...
October 26, 2018: Journal of Affective Disorders
https://read.qxmd.com/read/30400207/food-allergy-prevalence-in-salvadoran-schoolchildren-estimated-by-parent-report
#9
Francisco Cabrera-Chávez, Cecilia Ivonne Rodríguez-Bellegarrigue, Oscar Gerardo Figueroa-Salcido, Jesús Aristeo Lopez-Gallardo, Jesús Gilberto Arámburo-Gálvez, Marcela de Jesús Vergara-Jiménez, Mónica Lizzette Castro-Acosta, Norberto Sotelo-Cruz, Martina Hilda Gracia-Valenzuela, Noé Ontiveros
The prevalence of food allergy (FA) has not been estimated at a population level in Central American countries and, consequently, the magnitude and relevance of the problem in the Central American region remains unknown. Thus, our aim was to evaluate the parent-reported prevalence of FA in a population of schoolchildren from the Central American country El Salvador. A Spanish version of a structured questionnaire was utilized. Five hundred and eight (508) parents returned the questionnaire with valid responses (response rate, 32%)...
November 2, 2018: International Journal of Environmental Research and Public Health
https://read.qxmd.com/read/30373009/maillard-reaction-with-ribose-galacto-oligosaccharide-or-chitosan-oligosaccharide-reduced-the-allergenicity-of-shrimp-tropomyosin-by-inducing-conformational-changes
#10
Linglin Fu, Chong Wang, Jinbao Wang, Saiqiao Ni, Yanbo Wang
Tropomyosin (TM), the predominant shellfish allergen, has induced severe food allergy worldwide, but efficient prevention and cure measures are limited nowadays. In the present study, we introduced an approach to eliminate Penaeus chinensis TM by Maillard reaction with reducing sugars including ribose, galacto-oligosaccharide (GOS) and chitosan-oligosaccharide (COS), which reduced the allergenicity by up to 60%. We also evaluated the conformational changes of TM during reaction by far-UV circular dichroism, and found the reaction-induced alternation from α-helix to β-sheet...
February 15, 2019: Food Chemistry
https://read.qxmd.com/read/30336173/proteomic-profiling-of-the-white-shrimp-litopenaeus-vannamei-boone-1931-hemocytes-infected-with-white-spot-syndrome-virus-reveals-the-induction-of-allergy-related-proteins
#11
Ariadne Hernández-Pérez, Jesús Alejandro Zamora-Briseño, Eliel Ruiz-May, Alejandro Pereira-Santana, José Miguel Elizalde-Contreras, Sirenia Pozos-González, Edgar Torres-Irineo, Jorge Hernández-López, Martha Gabriela Gaxiola-Cortés, Rossanna Rodríguez-Canul
To elucidate the proteomic responses of shrimp hemocytes to white spot syndrome virus (WSSV) infection at the proteome level, a quantitative shotgun proteomic analysis was performed to detect differentially synthesized proteins in infected hemocytes of white shrimp (Litopenaeus vannamei). We identified 1528 proteins associated to 203 gene ontology (GO) categories. The most representative GO categories were regulation of cellular processes, organic substance metabolic processes and nitrogen compound metabolic processes...
February 2019: Developmental and Comparative Immunology
https://read.qxmd.com/read/29936683/the-role-of-dust-mites-in-allergy
#12
REVIEW
Jeffrey D Miller
House dust mites are an unsurpassed cause of atopic sensitization and allergic illness throughout the world. The major allergenic dust mites Dermatophagoides pteronyssinus, Dermatophagoides farinae, Euroglyphus maynei, and Blomia tropicalis are eight-legged members of the Arachnid class. Their approximately 3-month lifespan comprises egg, larval, protonymph, tritonymph, and adult stages, with adults, about one fourth to one third of a millimeter in size, being at the threshold of visibility. The geographic and seasonal distributions of dust mites are determined by their need for adequate humidity, while their distribution within substrates is further determined by their avoidance of light...
June 23, 2018: Clinical Reviews in Allergy & Immunology
https://read.qxmd.com/read/29887498/structural-and-dynamic-properties-of-allergen-and-non-allergen-forms-of-tropomyosin
#13
Jose K James, Douglas H Pike, I John Khan, Vikas Nanda
To what extent do structural and biophysical features of food allergen proteins distinguish them from other proteins in our diet? Invertebrate tropomyosins (Tpms) as a class are considered "pan-allergens," inducing food allergy to shellfish and respiratory allergy to dust mites. Vertebrate Tpms are not known to elicit allergy or cross-reactivity, despite their high structural similarity and sequence identity to invertebrate homologs. We expect allergens are sufficiently stable against gastrointestinal proteases to survive for immune sensitization in the intestines, and that proteolytic stability will correlate with thermodynamic stability...
July 3, 2018: Structure
https://read.qxmd.com/read/29798078/-multiple-factor-analysis-of-serum-allergen-distribution-of-patients-with-allergic-rhinitis-and-level-of-main-allergen-ige-in-shenyang-area
#14
Y L Chu, A H Yan, X H Tai, X J Jiang, L Hui, F F Jiang, Y Hu
Objective: To discuss multiple-factor analysis of serum allergen distribution of patients with allergic rhinitis and level of main allergen IgE in Shenyang area, and to provide a scientific basis for the prevention of allergic rhinitis in this area. Method: Serum IgE was detected in 749 cases[501 cases of male (66.8%), and 248 cases of female (33.2%)], with allergic rhinitis.The age range was from 3 to 65 years old, and they were divided into 5 groups based on age. A questionnaire survey was conducted to analyze the distribution of serum allergens and to carry out a multiple-factor analysis of level of the main allergen IgE in patients...
April 2018: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
https://read.qxmd.com/read/29751156/oral-allergy-syndrome-in-shrimp-and-house-dust-mite-allergies
#15
Karen Thursday S Tuano, Carla M Davis
No abstract text is available yet for this article.
November 2018: Journal of Allergy and Clinical Immunology in Practice
https://read.qxmd.com/read/29732297/oral-food-challenges-result-of-a-16-year-experience-at-a-major-teaching-hospital-in-thailand
#16
Witchaya Srisuwatchari, Pakit Vichyanond
Background: Prevalence of food allergy is increasing all over the world including in Asia. Diagnosis of food allergy in Asia is usually made after family complaints or by elimination and/or reintroduction foods. This could lead to an inaccurate diagnosis and to incorrect information on epidemiology of food allergy. We, herein, reported results of a 16-year experience (1996-2012) of oral food challenge (OFC) performed in pediatric patients at a major teaching hospital in Thailand. Objective: The major objectives of this report are to review types of foods selected for oral challenges, frequency of positive/negative challenges to these foods and the clinical reactions during challenges among these children...
April 2018: Asia Pacific Allergy
https://read.qxmd.com/read/29732295/self-reported-prevalence-of-clinical-features-of-allergy-to-nuts-and-seeds-and-seafood-in-university-students
#17
Ma Victoria Domínguez-García, Miriam V Flores-Merino, Cecilia Puente-Fernández, Jaime Morales-Romero, Martín Bedolla-Barajas
Background: In developing countries, there is a lack of epidemiological information related to food hypersensitivity, including nuts and seafood. Objective: The aim was to determine the prevalence of allergic reactions and clinical manifestations associated with the consumption of nuts and seeds or seafood in university students. Methods: We designed an observational cross-sectional study. A structured questionnaire was applied to Mexican university students to identify allergic reactions associated with the consumption of nuts and seeds, and seafood...
April 2018: Asia Pacific Allergy
https://read.qxmd.com/read/29732294/shellfish-crustacean-oral-allergy-syndrome-among-national-service-pre-enlistees-in-singapore
#18
Bernard Yu-Hor Thong, Shalini Arulanandam, Sze-Chin Tan, Teck-Choon Tan, Grace Yin-Lai Chan, Justina Wei-Lyn Tan, Mark Chong-Wei Yeow, Chwee-Ying Tang, Jinfeng Hou, Khai-Pang Leong
Background: All Singaporean males undergo medical screening prior to compulsory military service. A history of possible food allergy may require referral to a specialist Allergy clinic to ensure that special dietary needs can be taken into account during field training and deployment. Objective: To study the pattern of food allergy among pre-enlistees who were referred to a specialist allergy clinic to work up suspected food allergy. Methods: Retrospective study of all pre-enlistees registered in the Clinical Immunology/Allergy New Case Registry referred to the Allergy Clinic from 1 August 2015 to 31 May 2016 for suspected food allergy...
April 2018: Asia Pacific Allergy
https://read.qxmd.com/read/29731166/insect-food-allergy-and-allergens
#19
Steffie de Gier, Kitty Verhoeckx
Insects represent an alternative for meat and fish in satisfying the increasing demand for sustainable sources of nutrition. Approximately two billion people globally consume insects. They are particularly popular in Asia, Latin America, and Africa. Most research on insect allergy has focussed on occupational or inhalation allergy. Research on insect food safety, including allergenicity, is therefore of great importance. The objective of this review is to provide an overview of cases reporting allergy following insect ingestion, studies on food allergy to insects, proteins involved in insect allergy including cross-reactive proteins, and the possibility to alter the allergenic potential of insects by food processing and digestion...
August 2018: Molecular Immunology
https://read.qxmd.com/read/29655746/identification-of-pyruvate-kinase-as-a-novel-allergen-in-whiteleg-shrimp-litopenaeus-vannamei-by-specific-ige-present-in-patients-with-shrimp-allergy
#20
Chih-Hung Lee, Chia-Ching Wu, Yu-Chang Tyan, Wei-Tai Yu, Edward S Huang, Hsu-Sheng Yu
Food allergy is one of the most important health issues worldwide. In Taiwan, current literature suggests shrimps and crabs are the most common causes of food allergy, and are frequently associated with acute allergic reactions such as urticaria, atopic dermatitis, and asthma. However, knowledge regarding the shrimp allergens remains limited. Thus, there is an urgent need to establish comprehensive information for elucidating underlying triggers for food allergy. In this study, whiteleg shrimp (Litopenaeus vannamei) was used to evaluate the IgE-binding properties of various shrimp proteins to 7 allergic patients' sera by western blot...
August 30, 2018: Food Chemistry
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