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Age related hearing loss

H L Zhang, X C Gong, X J Hao, J Deng, H Y Liu, D Wu, X X Huo, R Guo
Objective: To investigate the hearing loss and speech disorders in the elderly, to analyze the risk factors of the elderly deafness, as well as to provide reference for the clinical research of the elderly deafness. Methods: From March 2016 to March 2018, 913 elderly people, who were tested for hearing and speech disorders, were examined by a unified questionnaire to investigate the demographic data of the subjects and the related factors of deafness, and the hearing and speech recognition tests were carried out...
February 7, 2019: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
T X Diao, Q H Han, H J Shan, X Q Wu, Y J Lin, Q Li, G H Wang, Y Y Jing, X Ma, M Shen, L S Yu, L Han, Y X Wang
Objective: To investigate the correlation between age-related hearing loss and cognitive impairment. Methods: 201 elderly patients, who were admitted to the Department of Otorhinolaryngology of Peking University People's Hospital from March 1, 2017 to March 31, 2017, were evaluated with hearing screening and the Montreal Cognitive Assessment Scale. Among them, 101 were female and 100 were male, aged 60-90 years old. Taking the cognitive level as the dependent variable, and taking the age, sex, education, occupation, marital status, residence, and average hearing loss (average hearing threshold of 500, 1 000, 2 000, and 4 000 Hz), as well as the length of conscious hearing loss as the independent variables, the single factor analysis and multivariate linear regression analysis were used to screen the main factors affecting the cognitive level of the elderly...
February 7, 2019: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
N Sai, W J Han, M M Wang, X Qin, T Zhang, W D Shen, J Liu, P Dai, S M Yang, D Y Han
Objective: To elucidate the clinical behavior, causes of misdiagnosis, surgical management, and outcomes of facial nerve schwannomas (FNS). Methods: A retrospective review in Chinese People's Liberation Army General Hospital from January 1, 2002 to December 31, 2015 was carried out and evaluated 110 patients with FNS, including 50 males and 60 females, aged 16-67 years old. The appropriate surgical strategy was selected based on each patient's clinical manifestations, facial nerve function, and imaging characteristics...
February 7, 2019: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
Małgorzata Pawlaczyk-Łuszczyńska, Kamil Zaborowski, Małgorzata Zamojska-Daniszewska, Adam Dudarewicz, Paulina Rutkowska-Kaczmarek
BACKGROUND: The aim of the study was to assess the noise exposure and risk of noise-induced hearing loss (NIHL) among users of communication headsets (CHs) or headphones. MATERIAL AND METHODS: Noise measurements and questionnaire surveys were carried out in 74 workers (aged: 31.8±7.3 years), including military aviation personnel (N = 12), transcribers (N = 18) and call center operators (N = 44). Sound pressure levels (SPLs) emitted by CHs (or headphones) were determined using the microphone in the real ear (MIRE) technique and artificial ear techniques according to PN-EN ISO 11904-1:2008 and CSA Z107...
February 15, 2019: Medycyna Pracy
Annerose Keilmann, Barbara Friese, Vanessa Hoffmann
OBJECTIVES: Many studies examining early bilingualism in migrant populations focus on the development of the first language. As language acquisition is closely related to the hearing development, there is a critical need to investigate language development in hearing-impaired children being raised bilingually who were fitted with cochlear implants and/or hearing aids. Therefore, this research project aimed to study the linguistic development of hearing-impaired children being raised with German as a second language who were provided with hearing aids or cochlear implants...
February 6, 2019: International Journal of Pediatric Otorhinolaryngology
Ángela Ros-Sanjuán, Sara Iglesias-Moroño, Marta Troya-Castilla, Bernarda Márquez-Márquez, Ismael Herruzo-Cabrera, Miguel Ángel Arráez-Sánchez
OBJECTIVE: The aims of our study were to evaluate tumour response in a series of patients with vestibular schwannoma (VS) treated with linear accelerator stereotactic radiosurgery (LINAC-RS), to describe the complications and to analyze the variables associated with the response to treatment. MATERIAL AND METHODS: This retrospective descriptive study included 64 patients treated from 2010 to 2016 with a minimum follow-up of one year, excluding patients with neurofibromatosis...
February 12, 2019: Neurocirugía
Selena E Briggs
Hearing loss is common in the geriatric population. Most hearing loss is associated with presbycusis or age-related hearing loss, impacting one-third of individuals over 65 years and increasing in prevalence with age. Hearing loss impacts quality of life, psychological health, and cognition. Implantable auditory devices are an exceptional option to improve hearing and quality of life. Various implantable auditory devices have been implemented safely with significant improvement in communication and performance on auditory tasks...
February 11, 2019: Otolaryngologic Clinics of North America
Katrina S McClannahan, Kristina C Backer, Kelly L Tremblay
OBJECTIVES: The goal of this study was to identify the effects of auditory deprivation (age-related hearing loss) and auditory stimulation (history of hearing aid use) on the neural registration of sound across two stimulus presentation conditions: (1) equal sound pressure level and (2) equal sensation level. DESIGN: We used a between-groups design, involving three groups of 14 older adults (n = 42; 62 to 84 years): (1) clinically defined normal hearing (≤25 dB from 250 to 8000 Hz, bilaterally), (2) bilateral mild-moderate/moderately severe sensorineural hearing loss who have never used hearing aids, and (3) bilateral mild-moderate/moderately severe sensorineural hearing loss who have worn bilateral hearing aids for at least the past 2 years...
February 11, 2019: Ear and Hearing
Peter Sarich, Karen Canfell, Emily Banks, Ellie Paige, Sam Egger, Grace Joshy, Rosemary Korda, Marianne Weber
BACKGROUND: Evidence suggests that people who develop serious health conditions are likely to cease drinking alcohol (sometimes known as 'sick-quitters'). We quantified the likelihood of quitting drinking in relation to the onset of a variety of health conditions. METHODS: Odds ratios (OR) and 95% confidence intervals (CI) of ceasing alcohol consumption after diagnosis of 28 health conditions and four general indicators of health were derived from logistic regression among 97,852 drinkers aged ≥45 years between baseline (2006-2009) and median 5...
February 13, 2019: Alcoholism, Clinical and Experimental Research
Teresa Partearroyo, Silvia Murillo-Cuesta, Néstor Vallecillo, Jose M Bermúdez-Muñoz, Lourdes Rodríguez-de la Rosa, Giacomo Mandruzzato, Adelaida M Celaya, Steven H Zeisel, María A Pajares, Gregorio Varela-Moreiras, Isabel Varela-Nieto
Betaine-homocysteine S-methyltransferases (BHMTs) are methionine cycle enzymes that remethylate homocysteine; hence, their malfunction leads to hyperhomocysteinemia. Epidemiologic and experimental studies have revealed a correlation between hyperhomocysteinemia and hearing loss. Here, we have studied the expression of methionine cycle genes in the mouse cochlea and the impact of knocking out the Bhmt gene in the auditory receptor. We evaluated age-related changes in mouse hearing by recording auditory brainstem responses before and following exposure to noise...
February 12, 2019: FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology
Sara Alhanbali, Piers Dawes, Rebecca E Millman, Kevin J Munro
OBJECTIVES: Listening effort can be defined as the cognitive resources required to perform a listening task. The literature on listening effort is as confusing as it is voluminous: measures of listening effort rarely correlate with each other and sometimes result in contradictory findings. Here, we directly compared simultaneously recorded multimodal measures of listening effort. After establishing the reliability of the measures, we investigated validity by quantifying correlations between measures and then grouping-related measures through factor analysis...
February 6, 2019: Ear and Hearing
Kristianna Mey, Michael Bille, Stig Hebbelstrup Rye Rasmussen, Lisbeth Tranebjærg, Per Cayé-Thomasen
INTRODUCTION: The aim was to investigate the progress of hearing loss over time in a cohort of pendred syndrome and non-syndromic enlarged vestibular aqueduct (PS/NSEVA) with one or two confirmed pathogenic variations in SLC26A4. STUDY DESIGN: Retrospective cohort study. SUBJECTS AND METHODS: At our tertiary referral center, a retrospective search of all patients with enlarged vestibular aqueduct, hearing loss and SLC26A4 mutations yielded 103 individuals by March 2017, 96 of whom had records of hearing levels; both an early audiometry and the latest between 3 and 668 months follow-up...
March 2019: Otology & Neurotology
Jan Löhler, Leif Erik Walther, Fynn Hansen, Philipp Kapp, Jörg Meerpohl, Barbara Wollenberg, Rainer Schönweiler, Christine Schmucker
BACKGROUND: Worldwide approximately 360 million people suffer from hearing impairment, 328 million of whom are adults. Up to now there has been no systematic evaluation of any representative epidemiological data on the prevalence of hearing loss among adults in Germany. The present paper is intended to investigate this within the framework of a systematic review. METHODS: A systematic literature search was carried out in electronic databases as well as by means of hand-searching...
February 9, 2019: European Archives of Oto-rhino-laryngology
Mariann Idstad, Kristian Tambs, Lisa Aarhus, Bo Lars Engdahl
BACKGROUND: Hearing loss is a global public health problem putting millions of people at risk of experiencing impediments in communication and potentially impaired mental health. Many studies in this field are based on small, cross sectional samples using self-report measures. The present study aims to investigate the association between childhood sensorineural hearing loss and mental health in adult men and women longitudinally in a large cohort with a matched control group, and hearing is measured by pure-tone audiometry...
February 8, 2019: BMC Public Health
Ragnhild Drage Berentsen, Bjørn I Haukanes, Pétur B Júlíusson, Karen Rosendahl, Gunnar Houge
A 4-generation family with multiple synostoses syndrome type 4 (SYNS4) is reported, the third family identified so far. The phenotype segregated with a previously undescribed Asn399Lys (c.1197C>A) substitution in GDF6 . N399 is part of a hydrophobic pocket critical for binding the BMP/GDF antagonist noggin. The N399K substitution renders GDF6 more similar to noggin-resistant members of the BMP family, namely GDF2 and BMP10, both of which contain lysine in the corresponding position. To further define the SYNS4 phenotype, we examined 6 of 9 affected family members...
January 2019: Molecular Syndromology
Jiwon M Lee, Kandai Nozu, Dae Eun Choi, Hee Gyung Kang, Ii-Soo Ha, Hae Ii Cheong
Alport syndrome (AS) is one of the most frequent hereditary nephritis leading to end-stage renal disease (ESRD). Although X-linked (XLAS) inheritance is the most common form, cases with autosomal recessive inheritance with mutations in COL4A3 or COL4A4 are being increasingly recognized. A systematic review was conducted on autosomal recessive Alport syndrome (ARAS). Electronic databases were searched using related terms (until Oct 10th, 2018). From 1601 articles searched, there were 26 eligible studies with 148 patients...
February 3, 2019: Journal of Clinical Medicine
D Z Shi, X F Zhang, Y J Huang, Z Q Luo
Objective: To compare the recovery of different times of intratympanic dexamethasone in the treatment of sudden sensorineural hearing loss(SSNHL) and investigate the related prognostic factors. Method: Ninety patients with SSNHL were randomly divided into group A(3 times, every 2 days) and group B(5 times, every 2 days) according to the times of intratympanic dexamethasone. All patients were treated with blood flow promoting agents and neural nutrients. After 2 weeks of treatment, the recovery was compared...
November 2018: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
Sara Ponticorvo, Renzo Manara, Josef Pfeuffer, Arianna Cappiello, Sofia Cuoco, Maria Teresa Pellecchia, Renato Saponiero, Donato Troisi, Claudia Cassandro, Marta John, Alfonso Scarpa, Ettore Cassandro, Francesco Di Salle, Fabrizio Esposito
Age-related hearing loss (HL) can be related to brain dysfunction or structural damage and may result in cerebral metabolic/perfusion abnormalities. Arterial spin labeling (ASL) magnetic resonance imaging (MRI) allows investigating noninvasively brain perfusion changes. Pseudocontinuous ASL and T1-weighted MRI (at 3 T) and neuropsychological testing (Montreal Cognitive Assessment) were performed in 31 HL (age range = 47-77 years, mean age ± SD = 63.4 ± 8.4 years, pure-tone average [PTA] HL > 50 dB) and 28 normal hearing (NH; age range = 48-78 years, mean age ± SD = 59...
February 4, 2019: Human Brain Mapping
Sharon G Curhan, Walter C Willett, Francine Grodstein, Gary C Curhan
INTRODUCTION: We examined the relation between self-reported hearing loss, hearing aid use, and risk of subjective cognitive function (SCF) decline. METHODS: We conducted an 8-year (2008-2016) longitudinal study of 10,107 men aged ≥62 years who reported their hearing status in 2006 and had no subjective cognitive concerns in 2008. Change in SCF scores was assessed by a 6-item questionnaire, and subjective decline was defined as new report of at least one SCF concern during follow-up...
January 21, 2019: Alzheimer's & Dementia: the Journal of the Alzheimer's Association
Roberta Vaccaro, Daniele Zaccaria, Mauro Colombo, Simona Abbondanza, Antonio Guaita
OBJECTIVE: Hearing loss is a common chronic condition in elderly people. The prevalence of disabling hearing loss among the elderly worldwide is 33% and in Italy ranges from 0.6% (profound hearing loss) to 39% (mild hearing loss). We investigated the relationship between self-reported hearing disability and clinician-evaluated hearing status, and its longitudinal consequences in relation to cognitive impairment and functional decline. We hypothesised that subjects who report that they have a hearing disability have a worse functional and cognitive profile than people who do not report having a hearing disability...
March 2019: Maturitas
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