Hongbo Gao, Li Sun, Dalong Ni, Libo Zhang, Han Wang, Wenbo Bu, Jinjin Li, Qianwen Shen, Ya Wang, Yanyan Liu, Xiangpeng Zheng
In the process of radiation therapy (RT), the cytotoxic effects of excited electrons generated from water radiolysis tend to be underestimated due to multiple biochemical factors, particularly the recombination between electrons and hydroxyl radicals (·OH). To take better advantage of radiolytic electrons, we constructed WO3 nanocapacitors that reversibly charge and discharge electrons to regulate electron transportation and utilization. During radiolysis, WO3 nanocapacitors could contain the generated electrons that block electron-·OH recombination and contribute to the yield of ·OH at a high level...
June 29, 2023: Journal of Nanobiotechnology