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(Intracranial OR brain) AND aneurysm

Dan Laukka, Melissa Rahi, Riitta Parkkola, Tero Vahlberg, Arttu Rintala, Eeva Salo, Jaakko Rinne
OBJECTIVEKawasaki disease (KD) is a vasculitis that can cause aneurysm formation in coronary arteries and, more rarely, in peripheral arteries. A possible connection between KD and intracranial aneurysms is unclear. The purpose of this study was to determine if KD is associated with intracranial aneurysms.METHODSIn this prospective cohort study, all patients hospitalized and diagnosed with KD in the authors' hospital district area in the period from 1978 to 1995 were identified. Patients with a current age ≥ 25 years and a history of KD in childhood were included in the study, which was conducted between 2016 and 2017...
February 15, 2019: Journal of Neurosurgery. Pediatrics
Goji Fushihara, Tomoya Kamide, Tatsuki Kimura, Ririko Takeda, Toshiki Ikeda, Yuichiro Kikkawa, Ryuichiro Araki, Hiroki Kurita
OBJECTIVE: The aim of the study was to better define the incidence of and risk factors for early seizures after repair of unruptured intracranial aneurysms in modern microsurgical techniques. PATIENTS AND METHODS: The medical records of 414 consecutive patients who underwent neck clipping of unruptured intracranial aneurysms in our institution over a 5-year period were retrospectively reviewed. Clinical and neuroimaging variables were analyzed to investigate putative predictors of perioperative seizures using multivariate logistic regression analysis...
February 8, 2019: Clinical Neurology and Neurosurgery
Alejandro Enriquez-Marulanda, Krishnan Ravindran, Mohamed M Salem, Luis C Ascanio, Peter Kan, Visish M Srinivasan, Christoph J Griessenauer, Clemens M Schirmer, Abhi Jain, Justin M Moore, Christopher S Ogilvy, Ajith J Thomas, Abdulrahman Y Alturki
BACKGROUND AND PURPOSE: Posterior communicating artery segment aneurysms are one of the most frequent intracranial aneurysms. Currently, there is limited literature describing the use of the pipeline embolization device in these aneurysms. MATERIAL AND METHODS: We conducted a multicenter retrospective review of 3 prospectively-collected databases of patients treated with pipeline between January 2013 and December 2017. The primary objective was to assess the efficacy and safety of the pipeline in the treatment of saccular posterior communicating artery aneurysms...
February 13, 2019: World Neurosurgery
Ching-Jen Chen, M Rao Patibandla, Min S Park, M Yashar Kalani
Despite the widespread use of the pipeline embolization device (PED), no complete aneurysm regrowth after its placement has been reported in the literature. We report the first case of aneurysm regrowth after the initial follow-up angiography demonstrating near-complete occlusion of the aneurysm and remodeling of the vessel with on-label PED use for a large 20 mm × 24 mm × 22 mm (width × depth × height) cavernous segment internal carotid artery (ICA) aneurysm. The patient was treated with two overlapping PED (4...
January 2019: Journal of Neurosciences in Rural Practice
Pervinder Bhogal, Joseph Lansley, Ken Wong, Sundip D Udani, Chris Uff, John Wadley, Atul Kumar, Charles C Matouk, Hegoda Ld Makalanda
Ruptured arteriovenous malformations are a frequently encountered pathology with significant associated morbidity and mortality. Identifying and securing the rupture point is mandatory; however, this can often be difficult. Black blood vessel wall magnetic resonance imaging is a promising technique for identifying ruptured saccular aneurysms and has been used in cases of multiple aneurysms. Here we describe a case of using this imaging technique to identify the rupture point in a ruptured arteriovenous malformation with histopathological correlation...
February 14, 2019: Interventional Neuroradiology
Mindy X Wang, Garrett Smith, Mehmet Albayram
Spinal cord watershed ischemia is a rare phenomenon often associated with cardiac arrest, prolonged hypotension, and atherosclerotic disease. It can manifest as central necrosis with peripheral sparing in the transverse axis, and central lesion with rostral and caudal sparing in the longitudinal axis. Few reports provide detailed imaging findings of spinal cord watershed ischemia lesions. We present a patient who experienced watershed infarcts of the brain and spinal cord following prolonged hypotension due to blood loss after an aortic aneurysm repair...
January 31, 2019: Clinical Imaging
Anna Tölli, Charlotte Höybye, Bo-Michael Bellander, Jörgen Borg
OBJECTIVE: To explore associations between pituitary dysfunction and clinical outcome at 12 months after traumatic brain injury and aneurysmal subarachnoid haemorrhage. METHODS: Prospective cohort study of 82 patients with traumatic brain injury and 45 with aneurysmal subarachnoid haemorrhage, included at 1 neurointensive care unit. Baseline data comprised age, sex, Glasgow Coma Scale (GCS) score, S100B and pupil light reactions. Hormone data were collected in the neurointensive care unit and 3, 6 and 12 months...
February 14, 2019: Journal of Rehabilitation Medicine
Fang Zhu, Jason Chui, Ian Herrick, Janet Martin
OBJECTIVES: We aim to evaluate the diagnostic test accuracy (DTA) of intraoperative evoked potential (EP) monitoring to detect cerebral injury during clipping of cerebral aneurysms. DESIGN: Systematic review. DATA SOURCES: Major electronic databases including MEDLINE, EMBASE, LILACS. ELIGIBILITY CRITERIA: We included studies that reported the DTA of intraoperative EP monitoring during intracranial aneurysm clipping procedures in adult patients...
February 12, 2019: BMJ Open
Zheng Feng, Guibo Lin, Ke Meng, Weidong Yu, Chao Fu
No abstract text is available yet for this article.
January 2019: Arquivos de Neuro-psiquiatria
Lindsay A Weiner, Adam C Richardson, Semhar Z Tewelde
BACKGROUND: Spontaneous spinal and intracranial subdural hematomas are rarely reported, especially occurring simultaneously. Anticoagulation use has been associated with spontaneous hemorrhages. Prompt diagnosis is required to prevent permanent neurological sequelae. In this case report, we describe a spontaneous spinal and intracranial subdural hematoma in a woman taking warfarin and initially presenting with severe vaginal pain. CASE REPORT: A 42-year-old woman who had a history of mechanical valve replacement and was therefore taking warfarin, came to an emergency department for relief of severe vaginal pain...
February 8, 2019: Journal of Emergency Medicine
David Lagier, David Tonon, Philippe Garrigue, Benjamin Guillet, Laura Giacomino, Jean-Charles Martin, Marie-Christine Alessi, Nicolas Bruder, Lionel J Velly
BACKGROUND: Several lipid metabolites in cerebrospinal fluid are correlated with poor outcomes in aneurysmal subarachnoid haemorrhage. Most of these metabolites bind to ubiquitous thromboxane-prostaglandin (TP) receptors, causing vasoconstriction and inflammation. Here, we evaluated terutroban (TBN), a specific TP receptor antagonist, for the prevention of post-haemorrhage blood-brain barrier disruption, neuronal apoptosis and delayed cerebral hypoperfusion. METHODS: The rat double subarachnoid haemorrhage model was produced by twice injecting (days 1 and 2) autologous blood into the cisterna magna...
February 11, 2019: Critical Care: the Official Journal of the Critical Care Forum
Tobias Engele, Christian Brettschneider, Pedram Emami, Hans-Helmut König
OBJECTIVE: Rupture of unruptured intracranial aneurysms (UIA) is the main cause for subarachnoid hemorrhage (SAH). UIA are widespread among the population. Advanced technology enables us to diagnose UIAs with increasing reliability and subsequently treat them. There are two main treatment options: surgical clipping and endovascular treatment of the aneurysm. This paper aims to analyze costs of neurosurgical clipping and the endovascular approach to treat UIA and to give an overview over the existing literature...
February 8, 2019: World Neurosurgery
Ririko Takeda, Hiroki Kurita
BACKGROUND: The treatment of complex unruptured middle cerebral artery (MCA) aneurysms which are untreatable with conventional surgical techniques are rare, and direct aneurysmal clipping usually remains the first-line treatment for large and giant saccular MCA aneurysms. Tandem clipping and multiple clipping techniques represent neck reconstruction in direct clipping surgeries that address for these aneurysms. CASE DESCRIPTION: The authors describe a simple variation of neck reconstructive clipping techniques for the large MCA unruptured aneurysm in a patient with an unruptured 20mm MCA bifurcation aneurysm...
February 8, 2019: World Neurosurgery
Peng Hu, Hong-Qi Zhang, Xiao-Yu Li, Xian-Zeng Tong
BACKGROUND: The STA connected to proximal MCA has been reported before. However, the flow supply capacity of the double-barrel STA to proximal MCA bypass in treating complex intracranial aneurysms has not been well documented. METHODS: Consecutive cases using this technique to treat complex intracranial aneurysms during the past five years have been collected. SEP and MEP monitoring were applied for each patient to determine any ischaemic events during the surgery...
February 8, 2019: World Neurosurgery
Huibin Man, Weiping Bi
BACKGROUND Preliminary microarray data in our laboratory indicated that the novel long noncoding RNA (lncRNA), GASL1, was downregulated in patients with intracranial aneurysms. This study aimed to investigate the expression of lncRNA GASL1 in patients with intracranial aneurysms and its role in the regulation of vascular smooth muscle cell (VSMC) proliferation by transforming growth factor-β1 (TGF-β1). MATERIAL AND METHODS The study included 68 patients with unruptured intracranial aneurysms and 56 healthy volunteers...
February 11, 2019: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
Chi-Man Yip, Huai-Pao Lee, Jui-Hsun Fu, Shuo-Hsiu Hsu
Intracranial solitary fibrous tumors are rare mesenchymal neoplasms originating in the meninges and constitute a heterogeneous group of rare spindle cell tumors that include benign and malignant neoplasms of which hemangiopericytoma is nowadays considered a cellular phenotypic variant. From literatures, the incidence of coexistence of brain tumors and intracranial aneurysms is ~0.7-5.4%. Meningioma is the most frequent tumor coexisted with intracranial aneurysms, followed by pituitary adenoma, neuroepithelial tumor, and metastatic tumor...
January 2019: Journal of Surgical Case Reports
Antonio Meola, Jianghong Rao, Navjot Chaudhary, Guosheng Song, Xianchuang Zheng, Steven D Chang
Magnetic particle imaging (MPI) is a novel radiation-free tomographic imaging method that provides a background-free, signal attenuation-free, direct quantification of the spatial distribution of superparamagnetic iron-oxide nanoparticles (SPIONs) with high temporal resolution (milliseconds), high spatial resolution (< 1 mm), and extreme sensitivity (μmol). The technique is based on non-linear magnetization of the SPIONs when exposed to an oscillating magnetic field. MPI was first described in 2001. Since then, the technique has been applied to experimental imaging of diseases affecting different organs in the human body...
February 7, 2019: World Neurosurgery
Hirokazu Koseki, Haruka Miyata, Satoshi Shimo, Nobuhiko Ohno, Kazuma Mifune, Kenjiro Shimano, Kimiko Yamamoto, Kazuhiko Nozaki, Hidetoshi Kasuya, Shuh Narumiya, Tomohiro Aoki
Intracranial aneurysm (IA) usually induced at a bifurcation site of intracranial arteries causes a lethal subarachnoid hemorrhage. Currently, IA is considered as a macrophage-mediated inflammatory disease triggered by a high wall shear stress (WSS) on endothelial cells. However, considered the fact that a high WSS can be observed at every bifurcation site, some other factors are required to develop IAs. We therefore aimed to clarify mechanisms underlying the initiation of IAs using a rat model. We found the transient outward bulging and excessive mechanical stretch at a prospective site of IA formation...
February 8, 2019: Translational Stroke Research
Jan-Karl Burkhardt, Michael T Lawton
INTRODUCTION: The aim of this study was to analyze practice trends in specific intracranial bypass types in a large, consecutuve bypass experience. METHODS: This retrospective review of a prospectively maintained database included all intracranial bypasses performed by a single surgeon over 21 years. Bypass types were grouped into 7 categories and analyzed in seven 3-year time intervals: type 1 = extracranial-to-intracranial (EC-IC) bypass with scalp arteries as donors; type 2 = EC-IC bypass with interposition graft to cervical carotid arteries; type 3 = arterial reimplantation; type 4 = in situ bypass; type 5 = reanastomosis; type 6 = intracranial-to-intracranial (IC-IC) bypass with interposition graft; and type 7= combination bypass...
February 5, 2019: World Neurosurgery
Caroline Der-Nigoghossian, Kimberly Levasseur-Franklin, Jason Makii
Optimal blood pressure management is controversial in neurocritically ill patients due to conflicting concerns of worsening ischemia with decreased blood pressure versus cerebral edema and increased intracranial pressure with elevated blood pressure. In addition, there is a lack of high-quality evidence regarding optimal blood pressure goals in patients with most of these conditions. This review summarizes guideline recommendations and examines the literature for blood pressure management in patients with ischemic stroke, intracerebral hemorrhage, aneurysmal subarachnoid hemorrhage, traumatic brain injury, and spinal cord injury...
February 7, 2019: Pharmacotherapy
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