keyword
https://read.qxmd.com/read/38485627/-update-for-cord-blood-unit-selection-in-hematopoietic-stem-cell-transplantation-workshop-sfgm-tc
#1
Valérie Dubois, Lucie Blandin, Marion Duclaut, Alix Duquesne, Lionel Faivre, Romain Ferru-Clement, Jean Roy, Alexandre Walencik, Leonardo Magro, Federico Garnier
Changing practices and the limited use of cord blood units as a source of cells for allogeneic hematopoietic stem cell transplants (HSC) led us to reconsider the recommendations established in 2011 and 2012, and to propose an update incorporating recent bibliographic data. If HLA compatibility was until now established at low resolution for HLA-A and B loci, and at high resolution for HLA-DRB1, the recent papers are converging towards an increase in the level of resolution, making way for a compatibility now defined in high resolution for all the considered loci, and the inclusion of the HLA-C locus, in order to establish a level of HLA compatibility on 8 alleles (HLA-A, B, C and DRB1)...
March 13, 2024: Bulletin du Cancer
https://read.qxmd.com/read/38242769/-cell-therapy-in-all-its-forms
#2
REVIEW
Aurore Dougé, Christophe Caux, Jacques-Olivier Bay
Immunotherapy strategies have revolutionized the management of a significant number of patients in recent years, whether they are undergoing treatment for hematologic malignancies or solid tumors. This therapeutic class is extensive, ranging from antibodies targeting immune checkpoint molecules to adoptive cell therapy strategies, including bispecific antibodies and anticancer vaccines. All these strategies are currently in active development. Adoptive cell therapy involves the infusion of normal or genetically modified immune cells into a patient with the aim of restoring strong antitumor immunity, primarily associated with the cytotoxicity of T lymphocytes...
January 18, 2024: Bulletin du Cancer
https://read.qxmd.com/read/37169605/-allogeneic-hematopoietic-stem-cell-transplantation-and-treatment-with-car-t-cells%C3%A2-%C3%A2-identification-of-psycho-social-vulnerability-factors-guidelines-from-the-francophone-society-of-bone-marrow-transplantation-and-cellular-therapy-sfgm-tc
#3
JOURNAL ARTICLE
Alice Polomeni, Malika Ainaoui, Aurélie Berr, Natacha de Bentzman, Marie Denis, Valérie Friser, Leonardo Magro, Ibrahim Yakoub-Agha
Allogeneic hematopoietic stem cell transplantation (HCT) and CAR-T cells therapy are treatments with curative aim for certain hematological malignancies, refractory or relapse. Nevertheless, they carry the risk of morbidity and mortality and may have a significant psychosocial impact, particularly for HCT. It is therefore necessary to identify psychological difficulties and social problems, as well as the patient's resources, and those of his entourage, in order to improve his overall management. The objective of this evaluation is not to pose contraindications to treatments, but to adapt the personalized care project...
May 9, 2023: Bulletin du Cancer
https://read.qxmd.com/read/37055307/-transfusion-management-and-immuno-hematological-follow-up-after-allogeneic-hematopoietic-cell-transplantation-recommendations-of-the-francophone-society-of-bone-marrow-transplantation-and-cellular-therapy-sfgm-tc
#4
Aliénor Xhaard, Muriel Bouton, Laurence Delugin, Christine Giraud, Alizée Guyon, Claudine Giroux-Lathuile, Khadija Hajjout, Pascal Nicolas, Thierry Peyrard, Vanessa Ratie, Anne Boisnard, Lucie Capelle, Sandrine Godin, Richard Traineau, Ibrahim Yacoub-Agha, Anne-Claire Leprêtre
The French High Authority of Health (HAS) and National Drug Safety (ANSM) agencies recommendations issued in 2014, the French General Direction of Health (DGS) instruction published in November 2021, the French National Blood Bank (EFS) guidelines and the data available in the literature globally define "good transfusion practices" but provide little information about the immuno-hematological and transfusion management of patients who have received an allogeneic hematopoietic stem transplantation (allo-HCT)...
April 11, 2023: Bulletin du Cancer
https://read.qxmd.com/read/36643941/risk-factors-of-aki-in-acute-respiratory-distress-syndrome-a-time-dependent-competing-risk-analysis-on-severe-covid-19-patients
#5
JOURNAL ARTICLE
Antoine Marchiset, Valerie Serazin, Omar Ben Hadj Salem, Claire Pichereau, Lionel Lima Da Silva, Siu-Ming Au, Christophe Barbier, Yann Loubieres, Jan Hayon, Julia Gross, Herve Outin, Matthieu Jamme
INTRODUCTION: Acute kidney injury (AKI) is frequently observed in patients with COVID-19 admitted to intensive care units (ICUs). Observational studies suggest that cardiovascular comorbidities and mechanical ventilation (MV) are the most important risk factors for AKI. However, no studies have investigated the renal impact of longitudinal covariates such as drug treatments, biological variations, and/or MV parameters. METHODS: We performed a monocentric, prospective, longitudinal analysis to identify the dynamic risk factors for AKI in ICU patients with severe COVID-19...
2023: Canadian Journal of Kidney Health and Disease
https://read.qxmd.com/read/36326787/the-neutrophil-to-lymphocyte-ratio-represents-a-systemic-inflammation-marker-and-reflects-the-relationship-with-90-day-mortality-in-non-cirrhotic-chronic-severe-hepatitis
#6
JOURNAL ARTICLE
Fu Chen Dong, Wen Ting Tan, Xian Bo Wang, Xin Zheng, Yan Huang, Bei Ling Li, Zhong Ji Meng, Yan Hang Gao, Zhi Ping Qian, Feng Liu, Xiao Bo Lu, Jia Shang, Yu Shi, Yu Bao Zheng, Hua Dong Yan, Yan Zhang, Bao Yan Xu, Yi Xin Hou, Qun Zhang, Yan Xiong, Cong Cong Zou, Jun Chen, Ze Bing Huang, Xiu Hua Jiang, Sen Luo, Yuan Yuan Chen, Na Gao, Chun Yan Liu, Wei Yuan, Xue Mei, Jing Li, Tao Li, Rong Jiong Zheng, Xin Yi Zhou, Jin Jun Chen, Guo Hong Deng, Xiang Xiao Mei, Wei Tuo Zhang, Hai Li
BACKGROUND AND OBJECTIVE: Systemic inflammatory responses are common in patients with chronic severe hepatitis (CSH) and increase their risk of mortality. Knowledge regarding the impact of the systemic inflammatory response on short-term outcomes in noncirrhotic CSH patients is limited. PATIENTS AND METHODS: We collected data from two prospective, multicenter cohorts from the CATCH-LIFE non-cirrhotic cohort. Cox regression was used to explore the association between systemic inflammation markers and 90-day liver transplant (LT)-free mortality...
November 3, 2022: Journal of Digestive Diseases
https://read.qxmd.com/read/36307324/-management-of-genetic-predisposition-to-hematologic-malignancies-in-patients-undergoing-allogeneic-hematopoietic-cell-transplantation-hct-guidelines-from-the-sfgm-tc
#7
JOURNAL ARTICLE
Valérie Coiteux, Laurène Fenwarth, Nicolas Duployez, Malika Ainaoui, Cécile Borel, Alice Polomeni, Ibrahim Yakoub-Agha, Yves Chalandon
The advent of new technologies has made it possible to identify genetic predispositions to myelodysplastic syndromes (MDS) and acute leukemias (AL) more frequently. The most frequent and best characterized at present are mutations in CEBPA, RUNX1, GATA2, ETV6 and DDX41 and, either in the presence of one of these mutations with a high allelic frequency, or in the case of a personal or family history suggestive of blood abnormalities such as non-immune thrombocytopenia, it is recommended to look for the possibility of a hereditary hematological malignancy (HHM)...
February 2023: Bulletin du Cancer
https://read.qxmd.com/read/35450721/kidney-graft-failure-and-patient-survival-modelling-based-on-competing-risks-under-nonproportional-hazards
#8
JOURNAL ARTICLE
Zdeněk Valenta, Damian Skrabaka, Aleksander Jerzy Owczarek, Aureliusz Kolonko, Robert Król, Andrzej Więcek, Jacek Ziaja
We analyze data on Silesian patients after kidney transplantation under competing events scenarios where time to death and time to graft failure are considered as absorbing competing events. Our objectives are to use model diagnostics in identifying violations of proportionality assumption under the framework of subdistribution and cause-specific hazards. We use the Fine-Gray proportional hazards model for the subdistribution. Under the cause-specific hazards (CSH) scenario we use the Cox proportional hazards model and Gray's time-varying coefficients model and available model diagnostics...
April 18, 2022: Transplantation Proceedings
https://read.qxmd.com/read/34526099/the-consensus-from-the-chinese-society-of-hematology-on-indications-conditioning-regimens-and-donor-selection-for-allogeneic-hematopoietic-stem-cell-transplantation-2021-update
#9
JOURNAL ARTICLE
Xiao-Hui Zhang, Jing Chen, Ming-Zhe Han, He Huang, Er-Lie Jiang, Ming Jiang, Yong-Rong Lai, Dai-Hong Liu, Qi-Fa Liu, Ting Liu, Han-Yun Ren, Yong-Ping Song, Zi-Min Sun, Xiao-Wen Tang, Jian-Min Wang, De-Pei Wu, Lan-Ping Xu, Xi Zhang, Dao-Bin Zhou, Xiao-Jun Huang
The consensus recommendations in 2018 from The Chinese Society of Hematology (CSH) on indications, conditioning regimens and donor selection for allogeneic hematopoietic stem cell transplantation (allo-HSCT) facilitated the standardization of clinical practices of allo-HSCT in China and progressive integration with the world. There have been new developments since the initial publication. To integrate recent developments and further improve the consensus, a panel of experts from the CSH recently updated the consensus recommendations, which are summarized as follows: (1) there is a new algorithm for selecting appropriate donors for allo-HSCT candidates...
September 15, 2021: Journal of Hematology & Oncology
https://read.qxmd.com/read/33962736/-donation-removal-and-transplantation-of-haematopoietic-stem-cells-legal-provisions
#10
JOURNAL ARTICLE
Daniel Maroudy
From donation to transplantation of hematopoietic stem cells, medullary origin, peripheral blood, placental or cord, legal provisions apply to the actors involved. Since 1994, the law on bioethics, its successive revisions and their implementing texts set the fundamental principles, rules and practical procedures to be followed.
April 2021: Soins; la Revue de Référence Infirmière
https://read.qxmd.com/read/32705137/plasma-cell-myeloma-presenting-with-amyloid-laden-crystal-negative-histiocytosis
#11
JOURNAL ARTICLE
Marc J Braunstein, Kseniya Petrova-Drus, Cara A Rosenbaum, David S Jayabalan, Adriana C Rossi, Steven Salvatore, Karen Rech, Roger N Pearse, Duane C Hassane, John Postley, Yuliya S Jhanwar, Julia T Geyer, Ruben Niesvizky
OBJECTIVES: Crystal-storing histiocytosis (CSH) is rare in plasma cell dyscrasias, with only 3 cases reported in the setting of amyloid. No cases of crystal-negative histiocytosis coincident with multiple myeloma and amyloidosis have been reported previously. METHODS: A 58-year-old woman presented with pain due to destructive bone lesions and was found to have plasma cell myeloma (PCM) and marrow amyloid deposition associated with crystal-negative histiocytosis...
November 4, 2020: American Journal of Clinical Pathology
https://read.qxmd.com/read/32020016/cyclosporine-h-improves-the-multi-vector-lentiviral-transduction-of-murine-haematopoietic-progenitors-and-stem-cells
#12
JOURNAL ARTICLE
Leonid Olender, Nir Bujanover, Omri Sharabi, Oron Goldstein, Roi Gazit
Haematopoietic stem cells (HSCs) have the potential for lifetime production of blood and immune cells. The introduction of transgenes into HSCs is important for basic research, as well as for multiple clinical applications, because HSC transplantation is an already established procedure. Recently, a major advancement has been reported in the use of cyclosporine H (CsH), which can significantly enhance the lentivirus (LV) transduction of human haematopoietic stem and progenitor cells (HSPCs). In this study, we employed CsH for LV transduction of murine HSCs and defined haematopoietic progenitors, confirming previous findings in more specific subsets of primitive haematopoietic cells...
February 4, 2020: Scientific Reports
https://read.qxmd.com/read/30241381/influence-of-eugenia-uniflora-extract-on-adhesion-to-human-buccal-epithelial-cells-biofilm-formation-and-cell-surface-hydrophobicity-of-candida-spp-from-the-oral-cavity-of-kidney-transplant-recipients
#13
JOURNAL ARTICLE
Luanda B F C Souza, Walicyranison P Silva-Rocha, Magda R A Ferreira, Luiz Alberto L Soares, Terezinha I E Svidzinski, Eveline P Milan, Regina H Pires, Ana Marisa Fusco Almeida, Maria José S Mendes-Giannini, Guilherme Maranhão Chaves
This study evaluated the influence of the extract of Eugenia uniflora in adhesion to human buccal epithelial cells (HBEC) biofilm formation and cell surface hydrophobicity (CSH) of Candida spp. isolated from the oral cavity of kidney transplant patients. To evaluate virulence attributes in vitro, nine yeasts were grown in the presence and absence of 1000 μg/mL of the extract. Adhesion was quantified using the number of Candida cells adhered to 150 HBEC determined by optical microscope. Biofilm formation was evaluated using two methodologies: XTT (2,3-bis(2-methoxy-4-nitro-5-sulfophenyl)-2 H -tetrazolium-5-carboxanilide) and crystal violet assay, and further analyzed by electronic scan microscopy...
September 20, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://read.qxmd.com/read/28062700/intravital-imaging-of-neutrophil-recruitment-reveals-the-efficacy-of-fpr1-blockade-in-hepatic-ischemia-reperfusion-injury
#14
JOURNAL ARTICLE
Masaki Honda, Takayuki Takeichi, Shintaro Hashimoto, Daiki Yoshii, Kaori Isono, Shintaro Hayashida, Yuki Ohya, Hidekazu Yamamoto, Yasuhiko Sugawara, Yukihiro Inomata
Neutrophils are considered responsible for the pathophysiological changes resulting from hepatic ischemia-reperfusion (I/R) injury, which is a complication of trauma, shock, liver resection, and transplantation. Recently, evidence is accumulating that formyl-peptide receptor (FPR) signaling constitutes an important danger signal that guides neutrophils to sites of inflammation. This study aimed to investigate dynamic neutrophil recruitment using two-photon laser-scanning microscopy (TPLSM) in response to FPR1 blockade during hepatic I/R...
February 15, 2017: Journal of Immunology
https://read.qxmd.com/read/25746240/an-in-vivo-swine-study-for-xeno-grafts-of-calcium-sulfate-based-bone-grafts-with-human-dental-pulp-stem-cells-hdpscs
#15
JOURNAL ARTICLE
Tzong-fu Kuo, Sheng-Yang Lee, Hong-Da Wu, Malosi Poma, Yu-Wei Wu, Jen-Chang Yang
The purpose of this in vivo study was to evaluate the effect of human dental pulp stem cells (hDPSCs) on various resorbable calcium sulfate/calcium phosphate bone grafts in bone regeneration. Granular particles of calcium sulfate dehydrate (CSD), α-calcium sulfate hemihydrate/amorphous calcium phosphate (α-CSH/ACP), and CSD/β-tricalcium phosphates (β-TCP) were prepared for in vitro dissolution and implantation test. The chemical compositions of specimen residues after dissolution test were characterized by XRD...
May 2015: Materials Science & Engineering. C, Materials for Biological Applications
https://read.qxmd.com/read/25649696/preoperative-hypercapnia-as-a-predictor-of-hypotension-during-anesthetic-induction-in-lung-transplant-recipients
#16
JOURNAL ARTICLE
Toshiyuki Mizota, Shino Matsukawa, Hiroshi Fukagawa, Hiroki Daijo, Tomoharu Tanaka, Fengshi Chen, Hiroshi Date, Kazuhiko Fukuda
OBJECTIVE: To determine the incidence and predisposing factors of hypotension during anesthetic induction in lung transplant recipients. DESIGN: Retrospective study. SETTING: University hospital. PARTICIPANTS: Patients who underwent lung transplantation between 2008 and 2013 (n = 68). INTERVENTIONS: None. MEASUREMENTS AND MAIN RESULTS: The authors analyzed the mean arterial pressure (MAP) from administration of anesthetic drugs to 10 minutes after endotracheal intubation (ie, the anesthetic induction) among participants who underwent lung transplantation...
August 2015: Journal of Cardiothoracic and Vascular Anesthesia
https://read.qxmd.com/read/25428052/improving-biodegradation-behavior-of-calcium-sulfate-bone-graft-tablet-by-using-water-vapor-treatment
#17
JOURNAL ARTICLE
Yu-Yu Tsai, Sea-Fue Wang, Shu-Ting Kuo, Wei-Hsing Tuan
The biodegradation rate of calcium sulfate hemihydrate (CSH) tablets is extremely rapid. This study adopts a water vapor treatment to modify the surface structure of a CSH tablet. After the treatment, a small amount of calcium sulfate dihydrate (CSD) forms on the surface; the porosity near the surface region decreases, consequently enhancing tablet strength and surface hardness. Because of the decrease in porosity at the surface, the time for complete disintegration increases from 1.2 h to 7.2 h; the time for complete dissolution increases from 7 days to 25 days...
January 1, 2013: Materials Science & Engineering. C, Materials for Biological Applications
https://read.qxmd.com/read/21745333/alveolar-bone-regeneration-around-immediate-implants-using-an-injectable-nhac-csh-loaded-with-autogenic-blood-acquired-mesenchymal-progenitor-cells-an-experimental-study-in-the-dog-mandible
#18
COMPARATIVE STUDY
Xue Han, Hongchen Liu, Dongsheng Wang, Fang Su, Yong Zhang, Wei Zhou, Shujun Li, Rui Yang
BACKGROUND: Lack of osseointegration between a dental implant and the walls of the alveolar bone is a common problem in immediate implantation. Injectable tissue-engineered bone (ITB) may be an effective and minimally invasive solution to the problem. In this study, an injectable bone cement, nHAC/CSH, which consists of nano-hydroxyapatite/collagen (nHAC) and calcium sulfate hemihydrate (CaSO4 .½H2 O; CSH) was investigated as a tissue-engineered scaffold material with blood-acquired mesenchymal progenitor cells (BMPC) as seeding cells...
June 2013: Clinical Implant Dentistry and related Research
https://read.qxmd.com/read/20206631/physiological-characterization-of-the-cold-shock-induced-humoral-factor-for-wing-color-pattern-changes-in-butterflies
#19
JOURNAL ARTICLE
Shah H A Mahdi, Shinichi Gima, Yuya Tomita, Hideo Yamasaki, Joji M Otaki
Butterfly wing color patterns can be modified by the application of temperature shock to pupae immediately after pupation, which has been attributed to a cold-shock-induced humoral factor called cold-shock hormone (CSH). Here, we physiologically characterized CSH and pharmacological action of tungstate, using a nymphalid butterfly Junonia orithya. We first showed that the precise patterns of modification were dependent on the time-point of the cold-shock treatment after pupation, and confirmed that the modification properties induced in a cold-shocked pupa were able to be transferred to another pupa in a parabiosis experiment...
September 2010: Journal of Insect Physiology
https://read.qxmd.com/read/20120925/-hydrophobic-properties-of-enterobacter-spp-rods
#20
JOURNAL ARTICLE
Anna Michalska, Eugenia Gospodarek
Enterobacter sp. is one of the important factors of hospital infections, especially at patients in intensive care, surgical and transplant units and cell surface hydrophobicity (CSH) plays an important role in the pathogenicity of many bacterial. Because of the increase of these bacteria in the infections, the aims of this study were the assessment of CSH of Enterobacter sp. strains on the basis of two methods: salt aggregation test (SAT) and bacterial adhesion to hydrocarbons (BATH). 175 strains of Enterobacter sp...
2009: Medycyna Doświadczalna i Mikrobiologia
keyword
keyword
168236
1
2
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.