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Meniscal tear

Duraisamy Shriram, Go Yamako, Etsuo Chosa, Yee Han Dave Lee, Karupppasamy Subburaj
BACKGROUND: Patients undergoing total or partial arthroscopic meniscectomy for treating traumatic meniscal tears are at greater risk of developing knee osteoarthritis (OA) due to increased mechanical load. The purpose of this study was to evaluate the effects of a valgus unloader brace in the medial meniscectomized knee joint during the gait cycle. METHODS: A three-dimensional finite element model of the knee joint was developed using the substructures segmented from magnetic resonance images...
February 12, 2019: Journal of Orthopaedic Surgery and Research
Michela Battistelli, Marta Favero, Debora Burini, Giovanni Trisolino, Dante Dallari, Lucia De Franceschi, Steven R Goldring, Mary B Goldring, Elisa Belluzzi, Giuseppe Filardo, Brunella Grigolo, Elisabetta Falcieri, Eleonora Olivotto
The human meniscus plays a crucial role for transmission and distribution of load across the knee, as well as shock absorption, joint stability, lubrication, and congruity. The aim of this study was to compare the complex geometry, and unique ultrastructure and tissue composition of the meniscus in healthy (control) and pathological conditions to provide understanding of structural changes that could be helpful in the future design of targetted therapies and improvement of treatment indications. We analyzed meniscus samples collected from 3 healthy multi-organ donors (median age, 66 years), 5 patients with traumatic meniscal tear (median age, 41 years) and 3 patients undergoing total knee replacement (TKR) for end-stage osteoarthritis (OA) (median age, 72 years)...
February 11, 2019: European Journal of Histochemistry: EJH
Vinay Kumaraswamy, Arun G Ramaswamy, Shyam Sundar, David V Rajan, Karthik Selvaraj, Santosh Sahanand, S Deebak
PURPOSE: Traditionally, MRI has not been used to predict meniscus tear reparability. An attempt has been made in this study to predict meniscal reparability using MRI, and a new scoring system to help with the same has been developed and tested. METHODS: Thirty repaired menisci were compared with equal number of meniscectomy cases retrospectively. Various clinical and radiological (radiographs and MRI) characteristics like chronicity of tear, pattern of tear, etc, were tabulated...
February 8, 2019: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
João V Novaretti, Neel K Patel, Jayson Lian, Ravi Vaswani, Darren de Sa, Alan Getgood, Volker Musahl
PURPOSE: To investigate the long-term survivorship rates and functional outcomes of meniscal allograft transplantation (MAT) in patients with minimum 10-year postoperative follow-up. METHODS: Two reviewers independently searched EMBASE, MEDLINE, and PubMed from database inception for literature related to MAT according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) checklist. Data are reported in a narrative summary fashion with descriptive statistics...
February 2019: Arthroscopy: the Journal of Arthroscopic & related Surgery
Nirav Amin, Louis McIntyre, Thomas Carter, John Xerogeanes, Jeffrey Voigt
PURPOSE: To determine whether needle arthroscopy (NA) compared with magnetic resonance imaging (MRI) in the diagnosis and treatment of meniscal tears is cost-effective when evaluated over a 2-year period via patient-reported outcomes. The hypothesis is that improved diagnostic accuracy with NA would lead to less costly care and similar outcomes. METHODS: A Markov model/decision tree analysis was performed using TreeAge Pro 2017 software. Patients were evaluated for degenerative and traumatic damage to the lateral/medial meniscus...
February 2019: Arthroscopy: the Journal of Arthroscopic & related Surgery
Alejandro Espejo-Reina, José Aguilera, María Josefa Espejo-Reina, María Pilar Espejo-Reina, Alejandro Espejo-Baena
PURPOSE: To analyze, in a long series of patients with knee injuries, the meniscal tear patterns in both stable and unstable knees to ascertain the exact proportion of such injuries that could have been repaired. METHODS: A descriptive cross-sectional study was undertaken by reviewing the clinical reports of arthroscopic knee operations carried out in 1 hospital. A total of 2,066 consecutive patients were included in the study. An analysis of clinical and anatomical data of knee lesions, including the shape of the meniscal tears and the surrounding injuries, was performed...
January 29, 2019: Arthroscopy: the Journal of Arthroscopic & related Surgery
Kun-Hui Chen, En-Rung Chiang, Hsin-Yi Wang, Hsiao-Li Ma
No abstract text is available yet for this article.
January 29, 2019: Journal of Knee Surgery
J M McKinney, T N Doan, L Wang, J Deppen, D S Reece, K A Pucha, S Ginn, R D Levit, N J Willett
Mesenchymal stem cells (MSCs) represent a great therapeutic promise in pre-clinical models of osteoarthritis (OA), but many questions remain as to their therapeutic mechanism of action: engraftment versus paracrine action. Encapsulation of human MSCs (hMSCs) in sodium alginate microspheres allowed for the paracrine signaling properties of these cells to be isolated and studied independently of direct cellular engraftment. The objective of the present study was to quantitatively assess the efficacy of encapsulated hMSCs as a disease-modifying therapeutic for OA, using a medial meniscal tear (MMT) rat model...
January 29, 2019: European Cells & Materials
Bum-Sik Lee, Seong-Il Bin, Jong-Min Kim, Min-Ho Park, Sang-Min Lee, Kun-Hyung Bae
BACKGROUND: Arthroscopic meniscectomy has been commonly performed for persistent pain caused by degenerative medial meniscal posterior root tears (MMPRTs). However, risk factors that affect long-term outcomes and joint survivorship after meniscectomy are unclear. PURPOSE: To identify the risk factors associated with end-stage osteoarthritis after arthroscopic meniscectomy for degenerative MMPRT for middle-aged or elderly patients and to determine the joint survivorship according to the identified risk factors...
January 23, 2019: American Journal of Sports Medicine
Alexander R Markes, Joseph Knox, Qunjie Zhong, Valentina Pedoia, Xiaojuan Li, C Benjamin Ma
Background: An altered tibial position is still present despite anterior cruciate ligament (ACL) reconstruction. It has been demonstrated that an abnormal tibial position after an ACL injury may play a role in subsequent injuries to the meniscus, which can lead to early cartilage degeneration. Purpose: To determine changes in both the tibial position and the meniscal matrix present before and after ACL reconstruction as well as to evaluate the association between these 2 variables in ACL-injured knees 3 years after reconstruction...
January 2019: Orthopaedic Journal of Sports Medicine
Jolanta Tomczyk, Maciej Rachalewski, Agnieszka Bianek-Bodzak, Marcin Domżalski
Evaluation with magnetic resonance imaging (MRI) is currently a gold standard for comprehensive posttraumatic assessment of the knee joint. Increasing availability of MR systems with stronger magnetic fields and new sequences results in higher resolution of images and thus allows imaging smaller and finer anatomical details, including different anatomical variations. This article focuses on anatomical variations of knee ligaments, which can mimics pathological structures. Well-known and less common ligaments that are sporadically observed and may raise the most doubt will be discussed...
January 21, 2019: Folia Morphologica (Warsz)
Lior Pariente, Itamar Ashkenazi, Roger Sevi, Yoram Folman
BACKGROUND: MRI is increasingly used as a diagnostic tool for sports injuries involving the knees before referral to arthroscopy. OBJECTIVES: Since degenerative changes increase with age, we aimed to evaluate whether age affects the accuracy of MRI. METHODS: This is a retrospective study of patients with knee injury whose evaluation included both MRI and arthroscopy. Two age groups were defined: young adults (18-39 years) and adults (40 years and above)...
January 2019: Harefuah
Floris R van Tol, Willem A Kernkamp, Robert J P van der Wal, Jan-Willem A Swen, Samuel K Van de Velde, Ewoud R A van Arkel
Two-stage revision anterior cruciate ligament (ACL) reconstruction is an effective way to revise suboptimal tunnel-placement allowing for proper graft fixation. However, prolonged increased laxity of the knee may increase the risk of meniscal or chondral injury. It was hypothesized that no additional meniscal or chondral lesions occur in between the two stages of the two-stage revision ACL reconstruction. In this retrospective study, 42 patients undergoing a two-stage revision ACL reconstruction were included...
January 18, 2019: Journal of Knee Surgery
Anıl Didem Aydın Kabakçı, Mustafa Büyükmumcu, Duygu Akın, Onur Bilge
PURPOSE: The aim of this study is to evaluate of morphometry of the lateral meniscus (LM) and determine incidence of the LM shapes. METHODS: This study was performed on fetal cadaver collection of Anatomy Department of Necmettin Erbakan University. Fifty human fetal cadavers (25 female, 25 male human fetal cadavers) were used in this study. Microdissection was performed. Morphometric measurements were performed. LM were classified into four types and five subtypes...
January 17, 2019: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
Lindsey A MacFarlane, Heidi Yang, Jamie E Collins, Ali Guermazi, Morgan H Jones, Kurt P Spindler, Amelia R Winter, Elena Losina, Jeffrey N Katz, Robert H Brophy, Brian J Cole, Bruce A Levy, Lisa A Mandl, Scott Martin, Robert G Marx, Mathew Matava, Clare Safran-Norton, Michael Stuart, Rick Wright
BACKGROUND: Arthroscopic partial meniscectomy (APM) is used to treat meniscal tears, although its efficacy is controversial. PURPOSE: This study used magnetic resonance imaging (MRI) to determine characteristics that lead to greater benefit from APM and physical therapy (PT) than from PT alone among patients with meniscal tear and knee osteoarthritis. STUDY DESIGN: Cohort study; Level of evidence, 2. METHODS: Using data from the Meniscal Tear in Osteoarthritis Research (MeTeOR) trial, the authors first assessed whether the effect of treatment on pain scores at 6 months differed according to baseline MRI features (bone marrow lesions, cartilage and meniscal damage)...
January 17, 2019: American Journal of Sports Medicine
Allen Nicholson, Logan Petit, Anthony Egger, Paul Saluan, Cordelia W Carter
Discoid meniscus is a rare anatomical variant with altered morphology and structure that can sometimes present symptomatically, typically in the pediatric population. The discoid meniscus is usually in the lateral compartment of the knee and is characterized by a partial or complete filling-in of central meniscal tissue, increased meniscal thickness, disorganization of longitudinal collagen fibers, and sometimes lack of peripheral attachments. These changes to both the macro- and micro-structure of the meniscus predispose affected patients to increased rates of both meniscal tears and mechanical symptoms...
December 2018: American Journal of Orthopedics
Cesar Praz, Thais Dutra Vieira, Adnan Saithna, Nikolaus Rosentiel, Vikram Kandhari, Helder Nogueira, Bertrand Sonnery-Cottet
BACKGROUND: Lateral meniscus posterior root tears (LMPRTs) result in loss of hoop forces and significant increases in tibiofemoral contact pressures. Preoperative imaging lacks reliability; therefore, holding an appropriate index of suspicion, based on the epidemiology of and risk factors for LMPRT, may reduce the rate of missed diagnoses. PURPOSE: The primary objectives of this study were to evaluate the incidence of and risk factors for lateral meniscus root lesions in a large series of patients undergoing anterior cruciate ligament (ACL) reconstruction...
January 16, 2019: American Journal of Sports Medicine
Michael A Donohue, Liang Zhou, Chad A Haley
Meniscal injuries in the young, active patient are often challenging injuries for the orthopaedic surgeon whose goal is to provide pain-free return to play/military duty and preserve maximal meniscal integrity. In the U.S. military, the incidence rate of meniscal tears is almost 10 times higher than that of the civilian population; although, the rates of reoperation following meniscal repair are fairly similar. The decision to pursue meniscal debridement versus repair is multifactorial depending on tear characteristics, concomitant injury, patient characteristics, and goals...
January 10, 2019: Journal of Knee Surgery
Masakazu Atobe, Takamichi Nagami, Shuji Muramatsu, Takeshi Ohno, Masayuki Kitagawa, Hiroko Suzuki, Masashi Ishiguro, Atsushi Watanabe, Masashi Kawanishi
Osteoarthritis (OA) is a degenerative disease characterized by joint destruction and loss of cartilage. There are many unmet needs in the treatment of OA and there are few promising candidates for disease-modifying OA drugs, particularly anabolic agents. Here, we describe the identification of novel quinazolin-4(3H)-one derivatives which stimulate chondrocyte cartilage matrix production via TRPV4 and mitigate damaged articular cartilage. We successfully identified the water-soluble, highly potent quinazolin-4(3H)-one derivative 36 and studied its intra-articular physicochemical profile to use in in vivo surgical OA model studies...
January 10, 2019: Journal of Medicinal Chemistry
Alana M Munger, Nicholas R Gonsalves, Natalya Sarkisova, Emily Clarke, Curtis D VandenBerg, J Lee Pace
BACKGROUND: Prior research has shown decreased accuracy of meniscal injury detection using magnetic resonance imaging (MRI) for anterior cruciate ligament (ACL)-deficient adult patients as well as ACL-deficient pediatric and adolescent patients. The objectives of this study were the following: (1) assess the diagnostic ability of MRI in detecting meniscal injuries for pediatric and adolescent patients undergoing arthroscopic ACL reconstruction and (2) characterize the unrecognized meniscal injuries...
January 8, 2019: Journal of Pediatric Orthopedics
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