keyword
https://read.qxmd.com/read/38523388/a-child-with-intravascular-fasciitis-mimicking-deep-vein-thrombosis-a-case-report
#1
Yeşim Yiğit, Oğuzhan Erdoğan, Ayşen Türedi Yıldırım, Erdener Özer, Hüseyin Gülen
BACKGROUND: Intravascular fasciitis (IF) is a benign, reactive, myofibroblastic proliferation that originates from the superficial or deep fascia of small / medium-sized arteries and veins. CASE REPORT: An 8-year-old male patient was admitted to a health center with the complaint of swelling in the inguinal region. Lower extremity venous Doppler ultrasonography showed deep vein thrombosis (DVT) of the femoral vein and anticoagulation with low-molecular weight heparin (LMWH) was initiated...
2024: Turkish Journal of Pediatrics
https://read.qxmd.com/read/38513152/intercalary-resection-of-the-tibia-for-primary-bone-tumors-are-vascularized-fibula-autografts-with-or-without-allografts-a-durable-reconstruction
#2
JOURNAL ARTICLE
Domenico Andrea Campanacci, Roberto Scanferla, Mariagrazia Marsico, Federico Scolari, Guido Scoccianti, Giovanni Beltrami, Luca Delcroix, Marco Innocenti, Rodolfo Capanna
BACKGROUND: Reconstruction with vascularized fibula grafts (VFG) after intercalary resection of sarcoma may offer longevity by providing early graft-host union and fracture healing. The ability of the fibula to hypertrophy under mechanical stress, as well as vascularized bone in the area, may also be advantageous, given that soft tissues may be compromised because of resection, chemotherapy, or radiation therapy. VFG with a massive allograft combines the primary mechanical stability of the graft with the biological potential of the vascularized fibula; however, complications and the durability of this combined reconstruction are not well described...
March 21, 2024: Clinical Orthopaedics and related Research
https://read.qxmd.com/read/38495393/deep-vein-thrombosis-as-the-presenting-sign-in-an-adolescent-with-new-onset-type-2-diabetes
#3
Felicia Cooper, Mauri Carakushansky, Craig M Johnson, Shilpa Gurnurkar
Prothrombin G20210A mutation occurs in only 2% to 3% of the population, but usually does not become apparent unless the individual exhibits another risk factor for clotting. A risk factor such as hyperglycemia in the setting of diabetes mellitus may accelerate this clotting process, even at a very young age. In this case report, we discuss a 15-year-old boy presenting with left calf swelling and pain, found to have extensive deep vein thrombosis in the setting of hyperglycemia and a newly discovered prothrombin G20210A mutation...
March 2024: JCEM Case Rep
https://read.qxmd.com/read/38491391/risk-factors-for-venous-thromboembolism-in-a-single-pediatric-intensive-care-unit-in-china
#4
JOURNAL ARTICLE
Jintuo Zhou, Yanting Zhu, Ying Liu, Hairong Zhan, Peiguang Niu, Huajiao Chen, Jinhua Zhang
BACKGROUND: Analyses of extensive, nationally representative databases indicate a rising prevalence of venous thromboembolism (VTE) among critically ill children. However, the majority of studies on childhood VTE have primarily concentrated on Caucasian populations in the United States and European countries. There is a lack of epidemiological studies on VTE in Chinese children. METHODS: We conducted a retrospective cohort study of data from the Pediatric Intensive Care (PIC) database...
March 15, 2024: Thrombosis Journal
https://read.qxmd.com/read/38484629/the-role-of-coagulation-factors-viii-ix-and-xi-in-the-prediction-and-mediation-of-recurrent-thrombotic-events-in-children-with-non-central-venous-catheter-deep-vein-thrombosis
#5
JOURNAL ARTICLE
Alessandra Bosch, Kirsten Brunsvig Jarvis, Leonardo R Brandão, Yushu Zhou, Jennifer Vincelli, Nour Amiri, Laura Avila
BACKGROUND: The role of elevated coagulation factors VIII (FVIII), FIX, FXI for the prediction of recurrent thrombotic events in children after an index non-central venous catheter (non-CVC) related deep vein thrombosis (DVT) remains unclear. OBJECTIVE: This study investigates the predictive role of FVIII, FIX, and FXI for recurrent thrombosis in children with index non-CVC DVTs, and the mediation effect of FVIII on chronic inflammation and recurrent thrombosis...
March 7, 2024: Thrombosis Research
https://read.qxmd.com/read/38480517/sequelae-and-post-thrombotic-syndrome-after-venous-thromboembolism-in-acute-lymphoblastic-leukemia-survivors-treated-on-the-nopho-all2008-protocol
#6
JOURNAL ARTICLE
Merete Dam, Line Stensig Lynggaard, Ólafur G Jónsson, Sonata Saulyte Trakymiene, Katrin Palk, Kirsten Jarvis, Liv Andrés-Jensen, Ruta Tuckuviene, Birgitte Klug Albertsen
The treatment of acute lymphoblastic leukemia (ALL) is frequently complicated by toxicity, including venous thromboembolism (VTE) affecting roughly 8% of patients. VTE can lead to post-thrombotic syndrome (PTS), a group of signs and symptoms developed as a complication to deep venous thrombosis (DVT), imposing risk of permanent disability and reduced quality of life (QoL). PTS prevalence ranges from 0% to 70%, reflecting very heterogenous cohorts and assessment tools. We aimed to estimate sequelae, including PTS and QoL in children and adults (<45 years old) who had a DVT during ALL treatment...
March 13, 2024: Pediatric Blood & Cancer
https://read.qxmd.com/read/38405595/case-report-in-situ-pulmonary-artery-thrombosis-in-a-12-year-old-girl-classified-as-systemic-lupus-erythematosus
#7
Yong Feng, Ning Chen, Bing Dai, Yunxiao Shang
In situ pulmonary artery thrombosis (ISPAT) is a relatively rare but potentially life-threatening complication of systemic lupus erythematosus (SLE) in children. We report the case of a 12-year-old girl who presented with fever, chest pain, and dyspnea. Immune thrombocytopenia was identified due to purpura and menorrhagia 3 months before presentation with a lowest platelet count of 12 × 109 /L. The sudden onset of fever, chest pain, and dyspnea were misdiagnosed as hyperinflammatory responses caused by pneumonia; these symptoms ameliorated with glucocorticoid and antibiotic treatment...
2024: Frontiers in Pediatrics
https://read.qxmd.com/read/38365603/pediatric-scurvy-case-report-a-novel-presentation-with-deep-vein-thrombosis-secondary-to-large-bilateral-spontaneous-iliac-subperiosteal-hematomas
#8
JOURNAL ARTICLE
Henry Charles de Boer, Jasdev Singh Sawhney
BACKGROUND: Scurvy is an uncommon disease in developed countries caused by deficiency of vitamin C. We present a case of scurvy in a 14-year-old male with autism with both novel presentation and imaging findings. This case had the novel presentation of lower limb deep vein thrombosis (DVT) secondary to compression of the external iliac vein from large bilateral iliac wing subperiosteal hematomas. Subperiosteal hematoma is a well-recognised feature of scurvy but large and bilateral pelvic subperiosteal hematoma causing DVT has not previously been described...
February 16, 2024: BMC Pediatrics
https://read.qxmd.com/read/38265429/machine-learning-prediction-model-of-major-adverse-outcomes-after-pediatric-congenital-heart-surgery-a-retrospective-cohort-study
#9
JOURNAL ARTICLE
Chaoyang Tong, Xinwei Du, Yancheng Chen, Kan Zhang, Mengqin Shan, Ziyun Shen, Haibo Zhang, Jijian Zheng
BACKGROUND: Major adverse postoperative outcomes (APOs) can greatly affect mortality, hospital stay, care management and planning, and quality of life. This study aimed to evaluate the performance of five machine learning (ML) algorithms for predicting four major APOs after pediatric congenital heart surgery and their clinically meaningful model interpretations. METHODS: Between August 2014 and December 2021, 23,000 consecutive pediatric patients receiving congenital heart surgery were enrolled...
January 23, 2024: International Journal of Surgery
https://read.qxmd.com/read/38206831/neuroimaging-of-neonatal-stroke-venous-focus
#10
JOURNAL ARTICLE
Lillian M Lai, Takashi Shawn Sato, Sedat Giray Kandemirli, Natally AlArab, Yutaka Sato
Perinatal venous infarcts are underrecognized clinically and at imaging. Neonates may be susceptible to venous infarcts because of hypercoagulable state, compressibility of the dural sinuses and superficial veins due to patent sutures, immature cerebral venous drainage pathways, and drastic physiologic changes of the brain circulation in the perinatal period. About 43% of cases of pediatric cerebral sinovenous thrombosis occur in the neonatal period. Venous infarcts can be recognized by ischemia or hemorrhage that does not respect an arterial territory...
February 2024: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://read.qxmd.com/read/38194094/similar-rate-of-venous-thromboembolism-vte-and-failure-of-non-operative-management-for-early-versus-delayed-vte-chemoprophylaxis-in-adolescent-blunt-solid-organ-injuries-a-propensity-matched-analysis
#11
JOURNAL ARTICLE
Areg Grigorian, Sebastian Schubl, Lourdes Swentek, Cristobal Barrios, Michael Lekawa, Dylan Russell, Jeffry Nahmias
BACKGROUND: Early initiation of venous thromboembolism (VTE) chemoprophylaxis in adults with blunt solid organ injury (BSOI) has been demonstrated to be safe but this is controversial in adolescents. We hypothesized that adolescent patients with BSOI undergoing non-operative management (NOM) and receiving early VTE chemoprophylaxis (eVTEP) (≤ 48 h) have a decreased rate of VTE and similar rate of failure of NOM, compared to similarly matched adolescents receiving delayed VTE chemoprophylaxis (dVTEP) (> 48 h)...
January 9, 2024: European Journal of Trauma and Emergency Surgery: Official Publication of the European Trauma Society
https://read.qxmd.com/read/38106767/an-evaluation-of-the-appropriateness-of-initial-enoxaparin-dosing-among-pediatric-patients
#12
JOURNAL ARTICLE
Abdullah Altuwayjiri, Amirah AlDarwish, Renad Alshuraim
Background Enoxaparin is a low molecular weight heparin that irreversibly inactivates factor Xa leading to the inhibition of clot formation. Despite the non-FDA approval in pediatrics, enoxaparin is recommended with an initial dose of 1.5mg/kg/q12hrs for patients aged ≤ 2 months and 1mg/kg/q12hrs for patients > 2 months, targeting therapeutic anti-Xa with a range of 0.5 to 1 units/mL. Due to more rapid clearance in pediatrics, our study aims to assess the need for initial higher doses than recommended by the guideline to reach the target anti-Xa level...
November 2023: Curēus
https://read.qxmd.com/read/38097769/technical-feasibility-and-clinical-efficacy-of-iliac-vein-stent-placement-in-adolescents-and-young-adults-with-may-thurner-syndrome
#13
JOURNAL ARTICLE
Frederic J Bertino, C Matthew Hawkins, Gary M Woods, Jay H Shah, Darshan E Variyam, Kavita N Patel, Anne E Gill
PURPOSE: To report technical feasibility and clinical efficacy of iliac vein stent placement in adolescent patients with May-Thurner Syndrome (MTS). MATERIALS AND METHODS: Single-institution retrospective review of the medical record between 2014 and 2021 found 63 symptomatic patients (F = 40/63; mean age 16.1 years, 12-20 years) who underwent left common iliac vein (LCIV) stent placement for treatment of LCIV compression from an overriding right common iliac artery, or equivalent (n = 1, left IVC)...
January 2024: Cardiovascular and Interventional Radiology
https://read.qxmd.com/read/38059918/uncovering-risk-factors-and-outcomes-of-pulmonary-embolism-in-a-nationwide-cohort-of-hospitalized-children
#14
JOURNAL ARTICLE
Carlos Theodore Huerta, Walter A Ramsey, Cindy Rodriguez, Joshua P Parreco, Chad M Thorson, Juan E Sola, Eduardo A Perez
PURPOSE: The incidence of pulmonary embolism (PE) in hospitalized children has increased in recent years. This study sought to characterize factors and outcomes associated with PE using a national pediatric cohort. METHODS: The Nationwide Readmissions Database was queried (2016-2018) for patients (<18 years) with a diagnosis of PE. Index and prior hospitalizations (PHs) within 1 year were analyzed. A binary logistic regression utilizing 37 covariates (demographics, procedures, comorbidities, etc...
December 7, 2023: American Surgeon
https://read.qxmd.com/read/38052364/tranexamic-acid-demonstrates-efficacy-without-increased-risk-for-venous-thromboembolic-events-in-cranial-neurosurgery-systematic-review-of-the-evidence-and-current-applications-in-nontraumatic-pathologies
#15
REVIEW
Nolan J Brown, Joelle N Hartke, Mark Pacult, Kyle R Burkett, Julian Gendreau, Joshua S Catapano, Michael T Lawton
BACKGROUND: The cautionary stance normally taken towards tranexamic acid (TXA) is rooted in concerns regarding its complication profile, namely its purported risk for venous thromboembolic events (VTEs). In the present review, we intend to bring increased attention to TXA as a remarkably valuable tool that does not appear to increase the risk for VTE when used as indicated in select patients. METHODS: We queried three databases to identify reporting use of TXA during nontraumatic cranial neurosurgery procedures (excluded traumatic brain injury)...
March 2024: World Neurosurgery
https://read.qxmd.com/read/37965418/pulmonary-embolism-in-an-adolescent-with-may-thurner-syndrome-a-case-report
#16
Mohammed Alpakra, Sameer M Al-Qahtani, Syed Rayees, Badriah G Alasmari, Mohamed F Bazeed
May-Thurner syndrome (MTS) is a pathological variant where the left iliac vein is compressed by the right iliac artery. Usually common in females between the third and fourth decades of life, this case report is about MTS in an adolescent girl. The patient was overweight and had a sedentary lifestyle. She developed a sudden onset of unilateral left leg deep venous thrombosis (DVT), leading to low-risk pulmonary embolism (PE) within a week of the symptoms starting. The patient received a heparin infusion for one week, after which she was switched to subcutaneous low-molecular-weight heparin...
October 2023: Curēus
https://read.qxmd.com/read/37919775/prothrombin-complex-concentrate-pcc-for-treatment-of-trauma-induced-coagulopathy-systematic-review-and-meta-analyses
#17
JOURNAL ARTICLE
Ioannis Hannadjas, Arthur James, Ross Davenport, Charlotte Lindsay, Karim Brohi, Elaine Cole
BACKGROUND: Trauma-induced coagulopathy (TIC) is common in trauma patients with major hemorrhage. Prothrombin complex concentrate (PCC) is used as a potential treatment for the correction of TIC, but the efficacy, timing, and evidence to support its use in injured patients with hemorrhage are unclear. METHODS: A systematic search of published studies was performed on MEDLINE and EMBASE databases using standardized search equations. Ongoing studies were identified using clinicaltrials...
November 2, 2023: Critical Care: the Official Journal of the Critical Care Forum
https://read.qxmd.com/read/37819408/percutaneous-treatment-of-symptomatic-deep-vein-thrombosis-in-adolescents-using-large-bore-thrombectomy-systems
#18
JOURNAL ARTICLE
Eric J Monroe, Michael A Woods, David S Shin, Joseph Reis, John Swietlik, Aaron Eifler, Jason W Pinchot, Jeffrey Forris Beecham Chick
BACKGROUND: While large-bore mechanical thrombectomy provides effective venous thrombus removal, often with avoidance of thrombolytics, literature surrounding the application of these devices in pediatric patients is sparse. OBJECTIVE: To report technical success and outcomes following large-bore thrombectomy systems in adolescent patients with deep venous thrombosis. MATERIALS AND METHODS: A retrospective review identified all patients less than 18 years of age undergoing mechanical venous thrombectomy at a single institution between 2018 and 2022...
October 11, 2023: Pediatric Radiology
https://read.qxmd.com/read/37731355/bedside-placement-of-tunneled-femorally-inserted-central-catheters-in-pediatric-patients-on-extracorporeal-life-support-a-case-series-and-discussion
#19
JOURNAL ARTICLE
Mark D Weber, Thomas Conlon, James Connelly, Adam S Himebauch
BACKGROUND: Pediatric patients requiring extracorporeal life support (ECLS) often need central venous access for extended periods of time. In this population, the placement of an upper extremity peripherally inserted central catheter (PICC) can be challenging due to the location and size of the venous ECLS cannula. Bedside placement of a tunneled femorally inserted central catheters (T-FICC) can be a viable alternative to a traditional PICC. METHODS: In this case series we present five children who were on ECLS and had a T-FICC placed at the bedside...
September 20, 2023: Journal of Vascular Access
https://read.qxmd.com/read/37594628/french-canadian-cross-cultural-adaptation-of-captsure%C3%A2-an-index-for-the-clinical-assessment-of-post-thrombotic-syndrome-in-children
#20
JOURNAL ARTICLE
Marie-Claude Pelland-Marcotte, Angelika Stavrakoukas, Gina Wong, Raoul Santiago, Laura Avila
PURPOSE: Post-thrombotic syndrome (PTS) is the most common complication of deep venous thrombosis (DVT). The index for the Clinical Assessment of Post-Thrombotic Syndrome in children (CAPTSure©) is a clinical tool for the diagnosis and severity rating of PTS in pediatric patients. The purpose of this study was to translate and adapt CAPTSure© for French-speaking patients. METHODS: We conducted a cross-sectional study to perform linguistic and cultural adaptation of CAPTSure©, using a rigorous translation process followed by cognitive debriefings in twenty French-speaking pediatric patients aged up to 18 years old with a history of upper or lower extremity DVT at least 6 months prior...
August 18, 2023: Journal of Patient-Reported Outcomes
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