Dana Hutton, Michelle Kameda-Smith, Fardad T Afshari, Ahmed Elawadly, Florence Hogg, Samir Mehta, James Samarasekara, Kristian Aquilina, Noor Ul Owase Jeelani, M Zubair Tahir, Dominic Thompson, Martin M Tisdall, Adikarige Haritha Dulanka Silva, James Hatcher, Greg James
OBJECTIVE: Invasive group A streptococcus (iGAS) infections are associated with a high rate of morbidity and mortality. CNS involvement is rare, with iGAS accounting for only 0.2%-1% of all childhood bacterial meningitis. In 2022, a significant increase in scarlet fever and iGAS was reported globally with a displacement of serotype, causing a predominance of the emm1.0 subtype. Here, the authors report on iGAS-related suppurative intracranial complications requiring neurosurgical intervention and prolonged antibiotic therapy...
July 7, 2023: Journal of Neurosurgery. Pediatrics