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https://read.qxmd.com/read/30776353/the-prognostic-value-of-nitrotyrosine-levels-in-coronary-heart-disease-long-term-evaluation-in-the-acute-coronary-syndrome-registry-strategy-erico-study
#1
Alessandra V L Quidim, Tatiana Bruno, Paola Caroline Lacerda Leocádio, Itamar S Santos, Jacqueline Isaura Alvarez-Leite, Penélope Lacrísio Dos Reis Menta, Paulo A Lotufo, Isabela M Benseñor, Alessandra C Goulart
INTRODUCTION: We aimed to analyze the association of nitrotyrosine (N-TYR) levels and long-term survival in an ongoing coronary heart disease (CHD) prospective cohort, the Acute Coronary Syndrome Registry Strategy (ERICO study). METHODS: N-TYR levels collected during acute and subacute phase from onset of acute coronary syndrome (ACS) symptoms (myocardial infarction and unstable angina) were evaluated in 342 patients. We calculated case-fatality rates (180-days, 1 year, 2 years and 4 years) and survival analyses up to 4 years using Kaplan-Meier curves and Cox regression with respective cumulative hazard ratios (95% confidence interval; 95%CI), according to N-TYR tertiles up to 4 years of follow-up...
February 15, 2019: Clinical Biochemistry
https://read.qxmd.com/read/30771889/detection-and-molecular-characterization-of-giardia-spp-in-captive-psittaciformes-in-brazil
#2
Ricardo Shoiti Ichikawa, Bruna Nicoleti Santana, Elis Domingos Ferrari, Isabela Garcia do Nascimento, Alex Akira Nakamura, Ana Rita Moraes Nardi, Marcelo Vasconcelos Meireles
This study aimed to perform the detection and molecular characterization of Giardia spp. in Psittaciformes from the Southern and Southeastern regions of Brazil. Fecal samples were obtained from 359 adult exotic captive Psittaciformes belonging to 13 genera, randomly selected from 33 aviaries located in the Southern and Southeastern regions of Brazil during a bird exhibition at the 2015 Ornithological Championship of the Ornithological Federation of Brazil (FOB). Nested polymerase chain reaction targeting the small subunit rRNA gene identified Giardia spp...
March 1, 2019: Preventive Veterinary Medicine
https://read.qxmd.com/read/30755151/maternal-bisphenol-a-exposure-disrupts-spermatogenesis-in-adult-rat-offspring
#3
Patricia De Campos, Isabela M Oliveira, Janaina Sena de Souza, Rodrigo Rodrigues Da Conceição, Gisele Giannocco, Maria I Chiamolera, Magnus R Dias-Da Silva, Marco A Romano, Renata Marino Romano
Bisphenol A (BPA) is an endocrine-disrupting chemical (EDC) that is widely used in the manufacturing of plastics and inner linings of food cans. Previously, it was reported that BPA disturbed the sexual dimorphic nucleus of the hypothalamus and delaying the onset of puberty attributed to an estrogenic action. In addition, BPA during the perinatal period increased LH serum concentrations in male offspring of dams at doses below the reproductive NOAEL (No Observable Adverse Effect Level) based upon World Health Organization guidelines...
February 12, 2019: Journal of Toxicology and Environmental Health. Part A
https://read.qxmd.com/read/30744173/advances-in-understanding-the-immunological-pathways-in-psoriasis
#4
REVIEW
Simona-Roxana Georgescu, Mircea Tampa, Constantin Caruntu, Maria-Isabela Sarbu, Cristina-Iulia Mitran, Madalina-Irina Mitran, Clara Matei, Carolina Constantin, Monica Neagu
Psoriasis vulgaris is a chronic, immune-mediated, inflammatory, polygenic skin disorder affecting approximately 2% of the population. It has a great impact on quality of life; patients often experience depression, anxiety, stigma as well as suicidal behavior. Even though psoriasis is one of the most studied dermatological conditions, the pathogenesis of the disease is still not completely elucidated. The complex interactions between keratinocytes, dendritic cells, T-lymphocytes, neutrophils and mast cells are responsible for the histopathological changes seen in psoriasis...
February 10, 2019: International Journal of Molecular Sciences
https://read.qxmd.com/read/30738256/bringing-value-to-the-chemical-industry-from-capture-storage-and-use-of-co-2-a-dynamic-lca-of-formic-acid-production
#5
Rubén Aldaco, Isabela Butnar, María Margallo, Jara Laso, Marta Rumayor, Antonio Dominguez-Ramos, Angel Irabien, Paul E Dodds
Low carbon options for the chemical industry include switching from fossil to renewable energy, adopting new low-carbon production processes, along with retrofitting current plants with carbon capture for ulterior use (CCU technologies) or storage (CCS). In this paper, we combine a dynamic Life Cycle Assessment (d-LCA) with economic analysis to explore a potential transition to low-carbon manufacture of formic acid. We propose new methods to enable early technical, environmental and economic assessment of formic acid manufacture by electrochemical reduction of CO2 (CCU), and compare this production route to the conventional synthesis pathways and to storing CO2 in geological storage (CCS)...
January 31, 2019: Science of the Total Environment
https://read.qxmd.com/read/30716992/tolerance-to-benzalkonium-chloride-and-antimicrobial-activity-of-butia-odorata-barb-rodr-extract-in-salmonella-spp-isolates-from-food-and-food-environments
#6
Louise Haubert, Maiara Lindemann Zehetmeyr, Ytacyana Maria Nascimento Pereira, Isabela Schneid Kroning, Darla Silveira Volcan Maia, Carla Pohl Sehn, Graciela Völz Lopes, Andreia Saldanha de Lima, Wladimir Padilha da Silva
Salmonellosis, caused by the consumption of contaminated foods, is a major health problem worldwide. The aims of this study were to assess the susceptibility of Salmonella spp. isolates to benzalkonium chloride (BC) disinfectant and the antimicrobial activity of Butia odorata Barb. Rodr. extract against the same isolates from food and food environments. Moreover, phenotypic and genotypic resistance profiles, the presence of virulence genes and biofilm forming ability were determined. The minimum inhibitory concentration (MIC) of B...
February 2019: Food Research International
https://read.qxmd.com/read/30716521/hematological-and-immune-changes-in-piaractus-mesopotamicus-in-the-sepsis-induced-by-aeromonas-hydrophila
#7
Gustavo S Claudiano, Jefferson Yunis-Aguinaga, Fausto A Marinho-Neto, Renata L Miranda, Isabela M Martins, Fabrizia S Otani, Antonio V Mundim, Cleni M Marzocchi-Machado, Julieta R E Moraes
The pathogenesis of sepsis involves complex systems and multiple interrelationships between the host and pathogen producing high mortality rates in various animal species. In this study, hematological disturbances, innate immunity and survival during the septic process in Piaractus mesopotamicus inoculated with Aeromonas hydrophila were studied. For this aim, fish blood samples were taken from control and infected groups 1, 3, 6, and 9 h post-inoculation (HPI). Leukogram showed reduction in the number of leukocytes and thrombocytes, followed by cessation of leukocyte chemotaxis 6 HPI and severe morphological changes in leukocytes and erythrocytes...
February 1, 2019: Fish & Shellfish Immunology
https://read.qxmd.com/read/30712238/bone-response-after-immediate-placement-of-implants-in-the-anterior-maxilla-a-systematic-review
#8
Ricardo Junior Denardi, Ricarda Duarte da Silva, Geninho Thomé, Augusto Ricardo Andrighetto, Rubens Moreno de Freitas, Roberto Hideo Shimizu, Isabela Almeida Shimizu, Ana Cláudia Moreira Melo
PURPOSE: The objective of this systematic review was to assess the three-dimensional changes in bone tissue after immediate installation of a single implant in a fresh extraction socket in the anterior maxilla. METHODS: After defining a strategy, an electronic search was carried out using the databases PubMed, Embase, LILACS, Web of Science, Cochrane, and Scopus. In addition, the gray literature was also researched using Google Scholar and ProQuest. Two reviewers independently screened for eligible studies, assessed the methodological quality, and extracted the data...
February 2, 2019: Oral and Maxillofacial Surgery
https://read.qxmd.com/read/30707454/atlantic-epiphytes-a-data-set-of-vascular-and-non-vascular-epiphyte-plants-and-lichens-from-the-atlantic-forest
#9
Flavio Nunes Ramos, Sara Ribeiro Mortara, Nathalia Monalisa-Francisco, João Pedro Costa Elias, Luiz Menini Neto, Leandro Freitas, Rodrigo Kersten, André Márcio Amorim, Fernando Bittencourt Matos, André Felippe Nunes-Freitas, Suzana Alcantara, Marcia Helena Nagahama Alexandre, Renata Jimenez de Almeida-Scabbia, Odair José Garcia de Almeida, Fernanda Eliane Alves, Rogério Marcos de Oliveira Alves, Francine Seehaber Alvim, Antônio Carlos Silva de Andrade, Simone de Andrade, Lidyanne Yuriko Saleme Aona, Andréa Cardoso Araujo, Kelianne Carolina Targino de Araújo, Vanessa Ariati, Julia Camara Assis, Cecília Oliveira de Azevedo, Bruno Ferreira Barbosa, Daniel Elias Ferreira Barbosa, Fernando Dos Reis Barbosa, Fabio de Barros, Geicilaine Alves Basilio, Fernando Antonio Bataghin, Fernanda Bered, Juliana Santos Bianchi, Christopher Thomas Blum, Carlos Renato Boelter, Annete Bonnet, Pedro Henrique Santin Brancalion, Tiago Bӧer Breier, Caio de Toledo Brion, Cristiano Roberto Buzatto, Andressa Cabral, Tiago João Cadorin, Eder Caglioni, Luciana Canêz, Pedro Henrique Cardoso, Fábia Silva de Carvalho, Renan Gonçalves Carvalho, Eduardo Luis Martins Catharino, Sergio Javier Ceballos, Monise Terra Cerezini, Ricardo Gomes César, Cesar Cestari, Cleber Juliano Neves Chaves, Vanilde Citadini-Zanette, Luiz Francisco Mello Coelho, João Vicente Coffani-Nunes, Renato Colares, Gabriel Dalla Colletta, Nadjara de Medeiros Corrêa, Andrea Ferreira da Costa, Grênivel Mota da Costa, Laís Mara Santana Costa, Natália Gabriela Souza Costa, Dayvid Rodrigues Couto, Caroline Cristofolini, Ana Carolina Rodrigues da Cruz, Leopoldo Angelo Del Neri, Mercedes di Pasquo, Aline Dos Santos Dias, Letícia do Carmo Dutra Dias, Ricardo Dislich, Marília Cristina Duarte, Juliano Ricardo Fabricante, Fernando Henrique Antoniolli Farache, Ana Paula Gelli de Faria, Claudenice Faxina, Mariana Terrola Martins Ferreira, Erich Fischer, Carlos Roberto Fonseca, Talita Fontoura, Talitha Mayumi Francisco, Samyra Gomes Furtado, Mauro Galetti, Mário Luís Garbin, André Luís de Gasper, Márcia Goetze, Janaína Gomes-da-Silva, Mateus Felipe Araujo Gonçalves, Diego Rafael Gonzaga, Ana Carolina Granero E Silva, André de Camargo Guaraldo, Ernestino de Souza Gomes Guarino, Aline Votri Guislon, Luigy Bitencourt Hudson, Jomar Gomes Jardim, Patricia Jungbluth, Selma Dos Santos Kaeser, Igor Musauer Kessous, Natália Mossmann Koch, Yoshiko Saito Kuniyoshi, Paulo Henrique Labiak, Maria Esther Lapate, Ana Carolina Laurenti Santos, Roberta Luísa Barbosa Leal, Felipe Silveira Leite, Paula Leitman, Ana Paula Liboni, Dieter Liebsch, Débora Vanessa Lingner, Julio Antonio Lombardi, Eve Lucas, Jhonny Dos Reis Luzzi, Patricia Mai, Luiz Felipe Mania, Waldir Mantovani, Angelica Guidoni Maragni, Marcia Cristina Mendes Marques, Gonzalo Marquez, Cristiane Martins, Laura do Nascimento Martins, Pedro Luiz Sanglard Silva Martins, Frederico Fregolente Faracco Mazziero, Camila de Aguiar Melo, Maria Margarida Fiuza de Melo, Alex Fernando Mendes, Letícia Mesacasa, Leonor Patricia Cerdeira Morellato, Vanessa de Souza Moreno, Adelcio Muller, Mariana Moreira da Silva Murakami, Edinete Cecconello, Camila Nardy, Michelle Helena Nervo, Beatriz Neves, Matheus Guimarães Cardoso Nogueira, Fabiana Regina Nonato, Ary Teixeira de Oliveira-Filho, César Pedro Lopes de Oliveira, Gerhard Ernst Overbeck, Gabriel Mendes Marcusso, Mateus Luís Barradas Paciencia, Patricia Padilha, Peterson Teodoro Padilha, Ana Clara Alves Pereira, Luciana Carvalho Pereira, Rodrigo Augusto Santinelo Pereira, Jimmy Pincheira-Ulbrich, José Salatiel Rodrigues Pires, Marco Aurélio Pizo, Kátia Cavalcanti Pôrto, Ludmila Rattis, Joice Rodrigues de Mendonça Reis, Simone Gonçalves Dos Reis, Thereza Christina da Rocha-Pessôa, Carlos Frederico Duarte Rocha, Fernando Souza Rocha, Alba Regina Pereira Rodrigues, Ricardo Ribeiro Rodrigues, Juliana Marcia Rogalski, Roberta Luiza Rosanelli, Andrés Rossado, Davi Rodrigo Rossatto, Débora Cristina Rother, Carlos Ramon Ruiz-Miranda, Felipe Zamborlini Saiter, Mauricio Bonesso Sampaio, Lucas Deziderio Santana, Juliana Silveira Dos Santos, Ricardo Sartorello, Marlies Sazima, Juliane Luzía Schmitt, Geniane Schneider, Bruna Grosch Schroeder, Lucia Sevegnani, Vasconcelos Oliveira Silva Júnior, Fernando Rodrigues da Silva, Maria Juliana da Silva, Mércia Patrícia Pereira Silva, Rafaela Guimarães Silva, Sandro Menezes Silva, Rodrigo Bustos Singer, Geovane Siqueira, Luis Eduardo Soares, Hildeberto Caldas de Sousa, Adriano Spielmann, Vinicius Rodrigues Tonetti, Maria Teresa Zugliani Toniato, Paulo Sérgio Bordoni Ulguim, Cássio van den Berg, Eduardo van den Berg, Isabela Galarda Varassin, Izabela Bitencourt Veloso da Silva, Alexander Christian Vibrans, Jorge Luiz Waechter, Erick Willy Weissenberg, Paulo Günter Windisch, Marina Wolowski, Agustina Yañez, Vania Nobuko Yoshikawa, Luciano Ramos Zandoná, Camila Martini Zanella, Elisabete Maria Zanin, Daniela Cristina Zappi, Valesca Bononi Zipparro, João Paulo Fernandes Zorzanelli, Milton Cezar Ribeiro
Epiphytes are hyper-diverse and one of the frequently undervalued life forms in plant surveys and biodiversity inventories. Epiphytes of the Atlantic Forest, one of the most endangered ecosystems in the world, have high endemism and radiated recently in the Pliocene. We aimed to (1) compile an extensive Atlantic Forest data set on vascular, non-vascular plants (including hemiepiphytes), and lichen epiphyte species occurrence and abundance; (2) describe the epiphyte distribution in the Atlantic Forest, in order to indicate future sampling efforts...
February 2019: Ecology
https://read.qxmd.com/read/30703427/isolation-and-physicochemical-characterization-of-different-lignin-streams-generated-during-the-second-generation-ethanol-production-process
#10
Rafael C A Castro, Isabela S Ferreira, Inês C Roberto, Solange I Mussatto
Four different lignin samples were isolated during the processing of rice straw for ethanol production: one after mild alkaline pretreatment (deacetylation) of rice straw, and other three after simultaneous saccharification and fermentation (fermentation residues), under different process conditions. Then, a complete chemical characterization in terms of main components (lignin, carbohydrates, among others) and elemental composition was performed for all the samples. Additionally, the structural and morphological characteristics, calorific value, thermal stability, solubility in solvents and antioxidant potential were also determined...
January 28, 2019: International Journal of Biological Macromolecules
https://read.qxmd.com/read/30698855/characteristics-of-referred-patients-with-twin-twin-transfusion-syndrome-who-did-not-undergo-fetal-therapy
#11
Elizabeth B Sasso, Macy T Hardley, Isabela Bottura, Lisa M Korst, Joseph G Ouzounian, Ramen H Chmait
INTRODUCTION: Abundant research has reported twin-twin transfusion syndrome (TTTS) outcomes following fetal therapy. Our research describes TTTS patients who did not undergo fetal therapy. METHODS: Records from TTTS pregnancies evaluated at 16-26 gestational weeks were reviewed between 1/2006 and 3/2017. The study population comprised subjects who did not undergo fetal therapy. Based on initial consultation, patients were grouped as non-surgical vs. surgical candidates...
January 30, 2019: Prenatal Diagnosis
https://read.qxmd.com/read/30693789/do-smokers-devaluate-smoking-cues-after-go-no-go-training
#12
Hanneke Scholten, Isabela Granic, Zhang Chen, Harm Veling, Maartje Luijten
OBJECTIVE: Smoking is one of the leading public health problems worldwide. The inability to quit smoking may be the result of the amplified value of smoking-related cues and inhibitory control deficits. Previous research has shown that pairing substance-related cues with no-go trials in go/no-go training reduces the value of these cues, an effect known as devaluation. The current experiment investigated the devaluation effect of go/no-go training on smoking-related cues, and compared this effect between smokers and nonsmokers...
January 29, 2019: Psychology & Health
https://read.qxmd.com/read/30681577/linear-and-nonlinear-analyses-of-heart-rate-variability-following-orthostatism-in-subclinical-hypothyroidism
#13
Rosangela A Hoshi, Rodrigo V Andreão, Itamar S Santos, Eduardo M Dantas, José Geraldo Mill, Paulo A Lotufo, Isabela M Bensenor
Subclinical hypothyroidism (SCHypo) is associated with autonomic disturbances that can interfere in physiological responses. This study was designed to evaluate linear and nonlinear variables of heart rate variability (HRV) following postural change, comparing subjects with SCHypo to euthyroid subjects.HRV analyses were performed in 5-minute time series collected in the supine and standing positions from a subsample of 855 participants of the ELSA-Brasil study. The cardiac autonomic nervous function was evaluated by linear time and frequency domain analyses (SDNN, RMSSD, LFms, HFms, and LF/HF ratio) as well as by nonlinear symbolic dynamics (0, 1, and 2 V)...
January 2019: Medicine (Baltimore)
https://read.qxmd.com/read/30679972/potential-pathogenic-mechanisms-involved-in-the-association-between-lichen-planus-and-hepatitis-c-virus-infection
#14
REVIEW
Simona Roxana Georgescu, Mircea Tampa, Madalina Irina Mitran, Cristina Iulia Mitran, Maria Isabela Sarbu, Ilinca Nicolae, Clara Matei, Constantin Caruntu, Monica Neagu, Mircea Ioan Popa
Lichen planus (LP) is an immune-mediated inflammatory disease that particularly affects the skin and mucous membranes. Its etiology remains elusive, however some trigger factors, including viral or bacterial antigens, drugs and metals, have been postulated. There is a higher prevalence of hepatitis C virus (HCV) infection among patients with LP, with some geographical variations. HCV is an enveloped RNA virus that belongs to the Flaviviridae family and in most instances causes chronic liver infections. It has been hypothesized that HCV may contribute to LP development, but the link between the two disorders is not fully understood...
February 2019: Experimental and Therapeutic Medicine
https://read.qxmd.com/read/30679967/correlations-between-related-purine-derivatives-and-renal-disorders-in-patients-with-psoriasis-vulgaris
#15
Ilinca Nicolae, Mircea Tampa, Corina Daniela Ene, Cristina Iulia Mitran, Madalina Irina Mitran, Maria Isabela Sarbu, Clara Matei, Cosmin Ene, Simona Roxana Georgescu
Recent data suggest that severe psoriasis is an independent risk factor for chronic renal disease. In the present study, we investigated the role of related-purine derivatives as predictors of renal dysfunctions in patients with psoriasis. A prospective study was conducted on a group of 45 patients with psoriasis vulgaris and 45 control cases, monitored over a 5-year period. Alterations of renal function, albumin/creatinine ratio (ACR, mg/g) and UA/creatinine ratio (UACR, mg/mg) were determined in spontaneous urine samples...
February 2019: Experimental and Therapeutic Medicine
https://read.qxmd.com/read/30673036/spinal-metallosis-as-a-complication-of-a-lodged-bullet-from-a-firearm-wound-an-image-centered-case
#16
Isabela Machado, Daniel de Paula Garcia, Carolina Souza Tannus, Koji Tanaka, Fred Bernardes Filho, Mauro Jose Brandao da Costa, Rodolfo Mendes Queiroz
No abstract text is available yet for this article.
August 2018: Revista da Associação Médica Brasileira
https://read.qxmd.com/read/30670457/the-timing-is-right-to-end-snakebite-deaths-in-south-asia
#17
Ravikar Ralph, Sanjib Kumar Sharma, Mohammad Abul Faiz, Isabela Ribeiro, Suman Rijal, François Chappuis, Ulrich Kuch
No abstract text is available yet for this article.
January 22, 2019: BMJ: British Medical Journal
https://read.qxmd.com/read/30670452/multidrug-resistant-enteric-fever-in-south-asia-unmet-medical-needs-and-opportunities
#18
Christopher M Parry, Isabela Ribeiro, Kamini Walia, Priscilla Rupali, Stephen Baker, Buddha Basnyat
No abstract text is available yet for this article.
January 22, 2019: BMJ: British Medical Journal
https://read.qxmd.com/read/30670439/a-pharmacokinetic-pharmacodynamic-assessment-of-the-hepatic-and-bone-marrow-toxicities-of-the-new-trypanoside-fexinidazole
#19
James A Watson, Nathalie Strub-Wourgraft, Antoine Tarral, Isabela Ribeiro, Joel Tarning, Nicholas J White
Fexinidazole is a novel oral treatment for Trypanosoma brucei gambiense , human African trypanosomiasis: g -HAT. Fexinidazole also has activity against T. cruzi the causative agent of Chagas disease. During the course of a dose ranging assessment in chronic indeterminate Chagas disease, delayed neutropenia and significant increases in hepatic transaminases were observed and clinical investigations were suspended. We retrospectively analyzed all available pharmacokinetic and pharmacodynamic data on fexinidazole in normal healthy volunteers and in patients with Chagas disease and g -HAT, to assess the determinants of toxicity...
January 22, 2019: Antimicrobial Agents and Chemotherapy
https://read.qxmd.com/read/30666679/polymyxin-b-clinical-outcomes-a-prospective-study-of-patients-undergoing-intravenous-treatment
#20
Karen P H Mattos, Isabela R Gouvêa, Júlia C F Quintanilha, Maria A Cursino, Pedro E N S Vasconcelos, Patricia Moriel
WHAT IS KNOWN AND OBJECTIVE: Polymyxins, especially polymyxin B, has become the last line of therapy against Gram-negative pathogens' carbapenemase producers. However, given increasing use of polymyxin B in clinical settings its therapeutic value has been evaluated worldwide due to its toxic effects. The aim of this study was to assess the efficacy and safety of antimicrobial therapy with polymyxin B in patients with multidrug-resistant bacteria in Brazil. METHODS: This was a prospective cohort study in a 403-bed academic tertiary care centre, located in the countryside of Brazil...
January 21, 2019: Journal of Clinical Pharmacy and Therapeutics
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