keyword
https://read.qxmd.com/read/38537186/can-the-width-of-lower-tongue-base-preoperative-sonography-measurements-predict-hypoxemia-during-esophagogastroduodenoscopy-under-sedation-in-asa-i-ii-patients
#1
JOURNAL ARTICLE
Hao Wu, Min Xia, Xu Chen, Sheng Wang, Wei Zhang
The most common complication during esophagogastroduodenoscopy (EGD) under sedation is hypoxemia. There is a scarcity of indicators to predict the risk of hypoxemia during EGD under sedation accurately. The width of the lower tongue base measured by ultrasound (US) is considered to be a significant predictor of the presence and severity of obstructive sleepapnea syndrome (OSAS), which develops hypoxemia by a similar mechanism to EGD under sedation. This study aimed to observe its ability to predict hypoxemia during EGD under sedation...
January 30, 2024: Medical Ultrasonography
https://read.qxmd.com/read/38537067/conventional-epithelial-off-corneal-crosslinking-in-patients-with-progressive-keratoconus-10-year-outcomes
#2
JOURNAL ARTICLE
Jérémy Bordais, Myriam Cassagne, David Touboul, Valentine Saunier, Jacqueline Butterworth, François Malecaze, Vincent Soler, Pierre Fournié
PURPOSE: Corneal crosslinking (CXL) is the standard treatment of progressive keratoconus (KC). We evaluated the safety and 10-year outcomes of conventional "epithelial-off" CXL for progressive KC for the first time in a cohort in France. METHODS: We conducted a retrospective review of patients undergoing conventional CXL (Dresden protocol) in our tertiary ophthalmology department from 2006 to 2011 with 10-year follow-up. The primary outcome was change in preoperative versus postoperative keratometry measured by maximum keratometry (Kmax), steep keratometry (K2), flat keratometry (K1), mean keratometry (Km), and topographic cylinder...
March 27, 2024: Cornea
https://read.qxmd.com/read/38536860/cost-effectiveness-of-a-pediatric-operating-room-installation-in-sub-saharan-africa
#3
JOURNAL ARTICLE
Ava Yap, Salamatu I Halid, Nancy Ukwu, Ruth Laverde, Paul Park, Greg Klazura, Emma Bryce, Maija Cheung, Elliot Marseille, Doruk Ozgediz, Emmanuel A Ameh
The unmet need for pediatric surgery imposes enormous health and economic consequences globally, predominantly shouldered by Sub-Saharan Africa (SSA) where children comprise almost half of the population. Lack of knowledge about the economic impact of improving pediatric surgical infrastructure in SSA inhibits the informed allocation of limited resources towards the most cost-effective interventions to bolster global surgery for children. We assessed the cost-effectiveness of installing and running two dedicated pediatric operating rooms (ORs) in a hospital in Nigeria with a pre-existing pediatric surgical service by constructing a decision tree model of pediatric surgical delivery at this facility over a year, comparing scenarios before and after the installation of the ORs, which were funded philanthropically...
2024: PLOS Glob Public Health
https://read.qxmd.com/read/38536626/construct-validity-of-eq-5d-5l-among-patients-with-inflammatory-bowel-disease-a-study-based-on-real-world-data-from-the-swedish-inflammatory-bowel-disease-registry
#4
JOURNAL ARTICLE
Jack Latteur, Olivia Ernstsson, Evalill Nilsson, Susanna Jäghult, Emelie Heintz
OBJECTIVES: The Swedish Inflammatory Bowel Disease Registry (SWIBREG) includes approximately 84% of all patients with inflammatory bowel disease (IBD) treated with immunomodulators, biologics or surgery in Sweden. Data on health-related quality of life (HRQoL) have been collected using EQ-5D-5L in the registry since 2012. Nevertheless, there are few studies assessing the validity of EQ-5D-5L in this patient population. Thus, the aim of this study was to assess the construct validity of EQ-5D-5L amongst patients with IBD (ulcerative colitis and Crohn's disease)...
March 27, 2024: Journal of Patient-Reported Outcomes
https://read.qxmd.com/read/38536518/prognostic-modeling-in-early-rheumatoid-arthritis-reconsidering-the-predictive-role-of-disease-activity-scores
#5
JOURNAL ARTICLE
Alix Bird, Lauren Oakden-Rayner, Luke A Smith, Minyan Zeng, Shonket Ray, Susanna Proudman, Lyle J Palmer
OBJECTIVE: In this prospective cohort study, we provide several prognostic models to predict functional status as measured by the modified Health Assessment Questionnaire (mHAQ). The early adoption of the treat-to-target strategy in this cohort offered a unique opportunity to identify predictive factors using longitudinal data across 20 years. METHODS: A cohort of 397 patients with early RA was used to develop statistical models to predict mHAQ score measured at baseline, 12 months, and 18 months post diagnosis, as well as serially measured mHAQ...
March 27, 2024: Clinical Rheumatology
https://read.qxmd.com/read/38536227/patient-education-and-decision-support-for-long-acting-injectable-hiv-antiretroviral-therapy-protocol-for-tool-development-and-pilot-testing-with-ryan-white-hiv-aids-program-medical-case-management-programs-in-new-york
#6
JOURNAL ARTICLE
Mary Kathryn Irvine, Rebecca Zimba, Tigran Avoundjian, Meghan Peterson, Connor Emmert, Sarah G Kulkarni, Morgan M Philbin, Elizabeth A Kelvin, Denis Nash
BACKGROUND: Long-acting injectable (LAI) HIV antiretroviral therapy (ART) presents a major opportunity to facilitate and sustain HIV viral suppression, thus improving health and survival among people living with HIV and reducing the risk of onward transmission. However, realizing the public health potential of LAI ART requires reaching patients who face barriers to daily oral ART adherence and thus can clinically benefit from alternative treatment modalities. Ryan White HIV/AIDS Program Part A medical case management (MCM) programs provide an array of services to address barriers to HIV care and treatment among economically and socially marginalized people living with HIV...
March 27, 2024: JMIR Research Protocols
https://read.qxmd.com/read/38536110/epidemiology-and-prognostic-significance-of-cough-in-fibrotic-interstitial-lung-disease
#7
JOURNAL ARTICLE
Yet H Khor, Kerri A Johannson, Veronica Marcoux, Jolene H Fisher, Deborah Assayag, Helene Manganas, Nasreen Khalil, Martin Kolb, Christopher J Ryerson
Rationale: Cough is a key symptom in patients with fibrotic interstitial lung disease (ILD). Objective: This study evaluated the prevalence, longitudinal change, associations, and prognostic significance of cough severity in patients with fibrotic ILD. Methods: We included consecutive patients with idiopathic pulmonary fibrosis (IPF) and non-IPF fibrotic ILD who completed the 100mm-Cough Severity Visual Analog Scale (VAS) from the prospective multi-center Canadian Registry for Pulmonary Fibrosis. Baseline cough severity and associations with patient demographics and clinical factors were determined...
March 27, 2024: American Journal of Respiratory and Critical Care Medicine
https://read.qxmd.com/read/38536086/frailty-as-a-comprehensive-health-measure-beyond-seizure-control-in-patients-with-epilepsy-a-cross-sectional-study
#8
JOURNAL ARTICLE
Emanuele Cerulli Irelli, Maria S Borioni, Alessandra Morano, Adolfo Mazzeo, Pierludovico Moro, Biagio Orlando, Enrico M Salamone, Luca Giordano, Alessio Petrungaro, Marco Toccaceli Blasi, Anna T Giallonardo, Marco Canevelli, Carlo Di Bonaventura
OBJECTIVE: Due to the high clinical heterogeneity of epilepsy, there is a critical need for novel metrics aimed at capturing its biological and phenotypic complexity. Frailty is increasingly recognized in various medical disciplines as a useful construct to understand differences in susceptibility to adverse outcomes. Here, we develop a frailty index (FI) for patients with epilepsy (PwE) and explore its association with demographic and clinical features. METHODS: In this cross-sectional study, we consecutively enrolled 153 PwE from an outpatient epilepsy clinic...
March 27, 2024: Epilepsia
https://read.qxmd.com/read/38536026/pelvic-exenteration-a-retrospective-study-in-a-tertiary-referral-cancer-center-in-the-uk
#9
JOURNAL ARTICLE
Konstantinos Palaiologos, Rebecca Karkia, Zoi Nikoloudaki, Ahmed Mohamed, Rebecca Lavelle, Susanne Booth, Marina Flynn, Christopher Helbren, Matthew Simms, Theo Giannopoulos
BACKGROUND: Pelvic exenteration (PE) is an extensive surgery that is indicated in cases of recurrent advanced gynecological cancer with curative and sometimes palliative intent. The procedure is associated with both high morbidity and mortality and as such is considered a highly specialist procedure. The aim of the study was to analyze surgical outcomes in women who underwent PE for advanced gynecological malignancy in a tertiary cancer referral center over 11 years. METHODS: This is an observational retrospective single-center study...
March 27, 2024: Minerva obstetrics and gynecology
https://read.qxmd.com/read/38536021/quality-measures-in-pre-liver-transplant-care-by-the-practice-metrics-committee-of-the-american-association-for-the-study-of-liver-diseases
#10
JOURNAL ARTICLE
Mayur Brahmania, Alexander Kuo, Elliot B Tapper, Michael Volk, Jennifer M Vittorio, Marwan Ghabril, Timothy Morgan, Fasiha Kanwal, Neehar D Parikh, Paul Martin, Shivang Mehta, Gerald S Winder, Gene Y Im, David Goldberg, Jennifer C Lai, Andres Duarte-Rojo, Angelo H Paredes, Arpan A Patel, Amandeep Sahota, Lisa M McElroy, Charlie Thomas, Anji E Wall, Maricar Malinis, Saima Aslam, Douglas A Simonetto, Nneka N Ufere, Sudha Ramakrishnan, Mary Margaret Flynn, Yasmin Ibrahim, Sumeet K Asrani, Marina Serper
INTRODUCTION: The LT evaluation and waitlisting process is subject to variations in care that can impede quality. The American Association for the Study of Liver Diseases (AASLD) Practice Metrics Committee (PMC) developed quality measures and patient-reported experience measures (PREMs) along the continuum of pre-LT care to reduce care variation and guide patient-centered care. METHODS: Following a systematic literature review, candidate pre-LT measures were grouped into four phases of care: referral, evaluation and waitlisting, waitlist management, and organ acceptance...
March 27, 2024: Hepatology: Official Journal of the American Association for the Study of Liver Diseases
https://read.qxmd.com/read/38535429/translation-adaptation-and-validation-of-the-greek-version-of-the-kerlan-jobe-orthopaedic-clinic-shoulder-and-elbow-score-in-greek-overhead-athletes
#11
JOURNAL ARTICLE
Eleftherios Paraskevopoulos, Anna Christakou, Stefanos Karanasios, Amalia Panagiota Louka, George M Pamboris, Maria Papandreou
Athletes engaging in overhead activities often face injury risks, emphasising the need for reliable assessment tools. This study focused on the translation and psychometric evaluation of the Kerlan-Jobe Orthopaedic Clinic (KJOC) Shoulder and Elbow Score into Greek (Gr-KJOC) for assessing upper limb function in Greek-speaking overhead athletes. The Gr-KJOC underwent meticulous translation and adaptation processes, ensuring linguistic equivalence and cultural relevance. A sample of 60 athletes participated in the psychometric evaluation, including assessments of internal consistency, test-retest reliability, construct validity, and structural validity...
March 12, 2024: Journal of Functional Morphology and Kinesiology
https://read.qxmd.com/read/38534997/comparison-of-transoral-and-transcervical-ultrasonography-with-mri-for-the-diagnostic-work-up-of-oropharynx-tumors-a-protocol-for-a-multicenter-clinical-trial-spotus
#12
JOURNAL ARTICLE
Martin Garset-Zamani, Gitte Bjørn Hvilsom, Thomas Kjærgaard, Christina Caroline Plaschke, Christoffer Holst Hahn, Mikkel Kaltoft, Padraig O'Leary, Natalie Lassen Frid, Rikke Norling, Danijela Dejanovic, Johanna Maria Hall, Tina Klitmøller Agander, Signe Bergliot Nielsen, Annette Kjær Ersbøll, Irene Wessel, Christian von Buchwald, Tobias Todsen
This study protocol for a prospective, multicenter, diagnostic, clinical trial describes the integration of transoral and transcervical ultrasonography (US) in the initial clinical work-up of patients referred to tertiary head and neck cancer centers with suspected oropharyngeal cancer. The study evaluates the blinded detection rate of oropharyngeal tumors and their US-estimated size and T-stage before histopathology and cross-sectional imaging are available. Magnetic resonance imaging (MRI) scans will be prospectively rated while blinded to T-site histopathology and US...
March 8, 2024: Diagnostics
https://read.qxmd.com/read/38534980/the-assessment-of-sf-36-survey-for-quality-of-life-measurement-after-radical-cystectomy-for-muscle-invasive-bladder-cancer-a-systematic-review
#13
REVIEW
Vlad Barbos, Bogdan Feciche, Silviu Latcu, Alexei Croitor, Vlad Dema, Razvan Bardan, Flaviu Ionut Faur, Tudor Mateescu, Dorin Novacescu, Gherle Bogdan, Alin Adrian Cumpanas
This study presents a systematic review of the literature on individuals' health-related quality of life (HRQoL) following radical cystectomy for muscle-invasive bladder cancer (MIBC), utilizing the Short Form-36 Health Survey (SF-36) as a primary assessment tool. The review was designed as an exhaustive literature search across three major databases including PubMed, Scopus, and Embase up to December 2023, using the PRISMA guidelines. The selection process refined 2281 identified articles down to 11 studies meeting our inclusion criteria...
March 16, 2024: Diseases (Basel)
https://read.qxmd.com/read/38534965/safety-and-efficacy-of-convalescent-plasma-combined-with-other-pharmaceutical-agents-for-treatment-of-covid-19-in-hospitalized-patients-a-systematic-review-and-meta-analysis
#14
REVIEW
Massimo Franchini, Daniele Focosi, Mario Cruciani, Michael J Joyner, Liise-Anne Pirofski, Jonathon W Senefeld, Shmuel Shoham, David J Sullivan, Arturo Casadevall
Plasma collected from people recovered from COVID-19 (COVID-19 convalescent plasma, CCP) was the first antibody-based therapy employed to fight the pandemic. CCP was, however, often employed in combination with other drugs, such as the antiviral remdesivir and glucocorticoids. The possible effect of such interaction has never been investigated systematically. To assess the safety and efficacy of CCP combined with other agents for treatment of patients hospitalized for COVID-19, a systematic literature search using appropriate Medical Subject Heading (MeSH) terms was performed through PubMed, EMBASE, Cochrane central, medRxiv and bioRxiv...
February 21, 2024: Diseases (Basel)
https://read.qxmd.com/read/38534946/a-retrospective-age-analysis-of-the-ambulatory-oncology-patient-satisfaction-survey-differences-in-satisfaction-across-dimensions-of-person-centred-care-and-unmet-needs-among-older-adults-receiving-cancer-treatment
#15
JOURNAL ARTICLE
Fay J Strohschein, Siwei Qi, Sandra Davidson, Claire Link, Linda Watson
Over half of all new cancer cases in Alberta are diagnosed among people aged 65+ years, a group that encompasses vast variation. Patient-reported experience measures are routinely collected within Cancer Care Alberta; however, the specific consideration of the needs and concerns of older Albertans with cancer is lacking. In 2021, 2204 adults who had received treatment at a cancer centre in Alberta completed the Ambulatory Oncology Patient Satisfaction Survey (AOPSS). In this study, we explored the age differences in satisfaction across six dimensions of person-centred care and in the proportions of unmet needs across eight types of issues, with specific attention to older adults...
March 13, 2024: Current Oncology
https://read.qxmd.com/read/38534125/long-term-outcome-of-the-sauv%C3%A3-kapandji-procedure-in-patients-with-post-traumatic-distal-radioulnar-joint-disorders
#16
JOURNAL ARTICLE
Gijs P Debeij, Pascal F W Hannemann, Jan A Ten Bosch
The aims of this study were to retrospectively assess the occurrence of complications or need for secondary wrist procedures after the Sauvé-Kapandji procedure, and to prospectively assess patient-reported outcomes at long-term follow-up. All patients treated with the Sauvé-Kapandji procedure in our tertiary referral hospital between January 2008 and September 2021 were identified and contacted to complete the Quick Disabilities of the Arm, Shoulder, and Hand and the Patient-Rated Wrist/Hand Evaluation outcome measures...
March 27, 2024: Journal of Hand Surgery, European Volume
https://read.qxmd.com/read/38534037/profilometric-esthetic-and-patient-reported-outcomes-of-the-l-shape-technique-combined-with-delayed-connective-tissue-grafting-in-the-maxillary-anterior-region-a-3-year-case-series-study
#17
JOURNAL ARTICLE
Yeon-Tae Kim, Jae-Hong Lee
OBJECTIVE: To evaluate the profilometric, esthetic, and patient-reported outcomes of peri-implant tissues in the maxillary anterior esthetic zone following guided bone regeneration (GBR) using the L-shape technique combined with delayed connective tissue grafting (CTG). MATERIALS AND METHODS: Profilometric and pink esthetic score (PES) measurements were performed at the time of implant surgery with GBR (T0) and at the 1- (T1), 2- (T2), and 3-year (T3) follow-up...
March 27, 2024: Journal of Esthetic and Restorative Dentistry
https://read.qxmd.com/read/38533997/benchmark-outcomes-for-distal-pancreatectomy-a-multicenter-prospective-snapshot-study-spandispan
#18
JOURNAL ARTICLE
José M Ramia, Cándido F Alcázar-López, Celia Villodre-Tudela, Juan J Rubio-García, Belén Hernández, Daniel Aparicio-López, Mario Serradilla-Martín
BACKGROUND: Improving the quality of care is a priority for health systems to obtain better care and reduce costs. One of the tools for measuring quality is benchmarking (BM). We presented a one-country prospective study of distal pancreatectomies (DP) and determined BM. STUDY DESIGN: Prospective, multicenter, observational snapshot study of DP carried out at Spanish HPB centers for a year (February 22-January 23). HPB centers were defined as high-volume if they performed > 10 DP per year...
March 27, 2024: Journal of the American College of Surgeons
https://read.qxmd.com/read/38533994/mobile-phone-text-messaging-for-medication-adherence-in-secondary-prevention-of-cardiovascular-disease
#19
REVIEW
Julie Redfern, Qiang Tu, Karice Hyun, Matthew A Hollings, Nashid Hafiz, Clara Zwack, Caroline Free, Pablo Perel, Clara K Chow
BACKGROUND: Cardiovascular diseases (CVDs) are the leading cause of death globally, accounting for almost 18 million deaths annually. People with CVDs have a five times greater chance of suffering a recurrent cardiovascular event than people without known CVDs. Although drug interventions have been shown to be cost-effective in reducing the risk of recurrent cardiovascular events, adherence to medication remains suboptimal. As a scalable and cost-effective approach, mobile phone text messaging presents an opportunity to convey health information, deliver electronic reminders, and encourage behaviour change...
March 27, 2024: Cochrane Database of Systematic Reviews
https://read.qxmd.com/read/38533919/accurate-robust-and-scalable-machine-abstraction-of-mayo-endoscopic-subscores-from-colonoscopy-reports
#20
JOURNAL ARTICLE
Anna L Silverman, Balu Bhasuran, Arman Mosenia, Fatema Yasini, Gokul Ramasamy, Imon Banerjee, Saransh Gupta, Taline Mardirossian, Rohan Narain, Justin Sewell, Atul J Butte, Vivek A Rudrapatna
BACKGROUND: The Mayo endoscopic subscore (MES) is an important quantitative measure of disease activity in ulcerative colitis. Colonoscopy reports in routine clinical care usually characterize ulcerative colitis disease activity using free text description, limiting their utility for clinical research and quality improvement. We sought to develop algorithms to classify colonoscopy reports according to their MES. METHODS: We annotated 500 colonoscopy reports from 2 health systems...
March 26, 2024: Inflammatory Bowel Diseases
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