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M I Davidov, N E Bunova
The study aimed to compare the efficacy and safety of Canephron N and ciprofloxacin as monotherapy in the management of mild forms of acute uncomplicated cystitis in women of working age. MATERIALS AND METHODS: A prospective, randomized study of Canephron N and ciprofloxacin for treating mild forms of acute uncomplicated cystitis (ACSS score less or equal 10) comprising 160 women aged 18-55 years was conducted from 2015 to 2017. Group I consisted of 80 women, who received oral Canephron N 2 tablets 3 times daily for 30 days...
October 2018: Urologii︠a︡
Shu-Fang Lv, Ming-Zhu Jia, Shan-Shan Zhang, Shuan Han, Jing Jiang
Ethylene and nitric oxide (NO) act as endogenous regulators during leaf senescence. Levels of ethylene or its precursor 1-aminocyclopropane-1-carboxylate acid (ACC) depend on the activity of ACC synthases (ACSs), and NO production is controlled by NO-associated 1 (NOA1). However, the integration mechanisms of ACSs and NOA1 activity still needs to be explored during leaf senescence. Here using some experimental techniques, such as physiological and molecular detection, liquid chromatograph-tandem mass spectrometry and fluorescence measurement, we investigated the relevant mechanisms...
February 8, 2019: Plant Biology
Yunchang Wu, Yiqing Wu, Gaurav Gangoli, Anh Bourcet, Walter Danker, Qianyi Gong, Huan Zhan, Wendong Chen, Zheng Wang
AIM: To assess the clinical and economic impact of flowable gelatin hemostatic matrix (FGHM) in anterior cervical spine surgery (ACSS). PATIENTS & METHODS: A total of 451 patients with performed ACSS were included to compare FGHM with conventional hemostatic methods for clinical and cost outcomes using propensity score matching method. RESULTS: The comparisons of the matched 125 pairs observed that FGHM was associated with significantly lower blood transfusion volume (11...
January 25, 2019: Journal of Comparative Effectiveness Research
Huan Mi, Hui Kou, Yao-di Chen, Hong Chen, Tao Wang
PURPOSE: To investigate social and cultural influence on preference of orthognathic surgery in patients with maxillofacial deformities through establishment of models, in order to provide motivational supports, improve treatment coordination and patients' satisfaction. METHODS: The orthognathic group included 137 patients with maxillofacial malformations, while the control group included 245 students from one university in Guizhou province. Acceptance of cosmetic surgery scale(ACSS), Orthognathic quality of life questionnaire(OQLQ) and sociocultural attitudes towards appearance questionnaire-3(SATAQ-3) were used in two groups...
October 2018: Shanghai Kou Qiang Yi Xue, Shanghai Journal of Stomatology
Feng Guo, Ting Ouyang, Taoxing Peng, Xiuying Zhang, Baogang Xie, Xiaoling Yang, Desheng Liang, Haijun Zhong
In this study, amphipathic chitosan derivative (ACS) and cell-penetrating peptide (CPP) co-modified colon-specific nanoparticles (CS-CPP NPs) were prepared and evaluated to improve the oral bioavailability of protein and peptide drugs. ACS modification was harnessed to protect CPPs from degradation in the stomach and small intestine after oral administration and achieve colon-specific drug delivery. After CS-CPP NPs reached the colon, ACSs on the surface of the NPs were gradually degraded and CPPs were exposed to bring into play the penetration efficacy in the colon epithelium...
January 23, 2019: Biomaterials Science
Wei Zhou, Ljiljana Rajic, Long Chen, Kaikai Kou, Yani Ding, Xiaoxiao Meng, Yan Wang, Biruk Mulaw, Jihui Gao, Yukun Qin, Akram N Alshawabkeh
Major challenges for effective implementation of the Electro-Fenton (EF) water treatment process are that conventional efficient cathodes are relatively expensive, and H2 O2 activation by Fe2+ may cause secondary pollution. Herein, we propose a low-cost activated carbon/stainless steel mesh (ACSS) composite cathode, where the SS mesh distributes the current and the AC simultaneously supports H2 O2 electrogeneration, H2 O2 activation, and organic compounds (OCs) adsorption. The oxygen-containing groups on the AC function as oxygen reduction reaction (ORR) sites for H2 O2 electrogeneration; while the porous configuration supply sufficient reactive surface area for ORR...
February 10, 2019: Electrochimica Acta
Shengjun Qian, Zhan Wang, Zefeng Zheng, Jisheng Ran, Junfeng Zhu, Weishan Chen
BACKGROUND The study aimed to develop a novel orthopedic surgical scaffold made of collagen and silk to repair the tendon and bone interface, and to investigate its influence on tendon and bone healing in a rabbit model. MATERIAL AND METHODS Four types of surgical scaffold were prepared, including a random collagen scaffold (RCS), an aligned collagen scaffold (ACS), a random collagen scaffold combined with knitted silk (RCSS), and an aligned collagen scaffold combined with knitted silk (ACSS). Rabbit bone marrow stem cells (BMSCs) were cultured and seeded onto the RCS and ACS scaffold...
January 9, 2019: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
Francesco Paciullo, Stefania Momi, Paolo Gresele
Since increased cholesterol levels are crucial in determining the development of atheroma, their reduction represents a mainstay in primary and secondary cardiovascular prevention. The most recent spectacular advancement in cholesterol-lowering therapy is represented by proprotein convertase subtilisin/kexin type-9 (PCSK9) inhibitors. Although their benefit over currently available treatments has been ascribed primarily to their strong low-density lipoprotein (LDL)-cholesterol reducing action, several clues suggest that PCSK9 inhibitors may also influence platelet function and blood coagulation...
January 3, 2019: Thrombosis and Haemostasis
AbdulMajid Al-Mqdashi, Aduwati Sali, Nor Kamariah Noordin, Shaiful J Hashim, Rosdiadee Nordin
Channel rendezvous is an initial and important process for establishing communications between secondary users (SUs) in distributed cognitive radio networks. Due to the drawbacks of the common control channel (CCC) based rendezvous approach, channel hopping (CH) has attracted a lot of research interests for achieving blind rendezvous. To ensure rendezvous within a finite time, most of the existing CH-based rendezvous schemes generate their CH sequences based on the whole global channel set in the network. However, due to the spatial and temporal variations in channel availabilities as well as the limitation of SUs sensing capabilities, the local available channel set (ACS) for each SU is usually a small subset of the global set...
December 10, 2018: Sensors
Eric Gomez-Urena, Rafael J Sierra, Kerryl E Greenwood-Quiantance, Melissa J Karau, James M Steckelberg, Robin Patel
Diagnosis of persistent infection at the time of reimplantation for staged revision of infected arthroplasties is challenging. Implant sonication culture for the diagnosis of prosthetic joint infection (PJI) has improved sensitivity compared to standard periprosthetic tissue culture. We report our experience with periprosthetic tissue culture and sonication culture of antimicrobial agent-containing cement spacers (ACSs) collected during second stages of staged revisions for arthroplasty infection. We studied 87 ACSs from 66 patients undergoing two-stage revision arthroplasty for PJI submitted for sonication culture along with conventional periprosthetic tissue cultures...
December 12, 2018: Journal of Clinical Microbiology
Jingwei Liu, Yiqi Zhang, Yong Hai, Nan Kang, Bo Han
PURPOSE: To conduct a high-level systematic review of the literature to evaluate intravenous and local steroid use in the management of dysphagia after anterior cervical spine surgery. METHODS: We searched the database PubMed, EMBASE, Clinical key, the Cochrane library and Wiley Online Library without time restriction using the terms 'dysphagia' or 'odynophagia' or 'swallowing disorder,' 'steroid,' 'anterior cervical spine surgery.' Randomized controlled trails (RCTs) were selected, and effects of intravenous and local steroids were investigated from these studies...
November 30, 2018: European Spine Journal
Jakhongir F Alidjanov, Kurt G Naber, Ulugbek A Abdufattaev, Adrian Pilatz, Florian M Wagenlehner
BACKGROUND AND OBJECTIVES: Acute uncomplicated cystitis (AC) is common among women. Acute onset of specific typical symptoms may serve as reliable criteria for developing a cost-effective strategy to make an accurate diagnosis of AC. We aimed to evaluate the diagnostic values of most common symptoms and signs of AC depending on their presence and severity. METHODS: The current trial was designed as a case-control study. Data derived from the Acute Cystitis Symptom Score (ACSS) database were analyzed...
2019: Urologia Internationalis
Christian Büsel, Ulrich Pomper, Ulrich Ansorge
We investigated the origin of attention capture in the contingent-capture protocol during a search for two colors. When searching for the target color, cues similar to the target capture attention but cues dissimilar to the target do not capture attention. The results are typically explained by top-down contingent capture, a form of proactive control where participants set up attentional control settings (ACSs) for the target and cues matching the ACSs capture attention. However, based on recent research, we hypothesized that the situation could be more complicated during search for several features...
November 6, 2018: Psychonomic Bulletin & Review
Chan Ho Park, Jeehee Roh, Ji-Hyun Youn, Seung-Hyun Son, Ji Hye Park, Soon Young Kim, Tae-Wuk Kim, Seong-Ki Kim
Ethylene regulates numerous aspects of plant growth and development. Multiple external and internal factors coordinate ethylene production in plant tissues. Transcriptional and post-translational regulations of ACC synthases (ACSs), which are key enzymes mediating a rate-limiting step in ethylene biosynthesis have been well characterized. However, the regulation and physiological roles of ACC oxidases (ACOs) that catalyze the final step of ethylene biosynthesis are largely unknown in Arabidopsis. Here, we show that Arabidopsis ACO1 exhibits a tissue-specific expression pattern that is regulated by multiple signals, and plays roles in the lateral root development in Arabidopsis...
October 31, 2018: Molecules and Cells
Maximilian Tscharre, Robert Herman, Miklos Rohla, Edita Piackova, Kris G Vargas, Serdar Farhan, Matthias K Freynhofer, Thomas W Weiss, Kurt Huber
BACKGROUND: Patients with familial hypercholesterolemia (FH) are at increased risk for premature and subsequent cardiovascular disease. Data on long-term major adverse cardiovascular events (MACE) in patients with FH after percutaneous coronary intervention (PCI) in the era of high-intensity statins are scarce. OBJECTIVE: We assessed the prognostic impact of clinically diagnosed FH on long-term MACE, a composite of all-cause death, myocardial infarction, and ischemic stroke in patients admitted for stable coronary artery disease (SCAD) or acute coronary syndromes (ACSs) undergoing PCI...
September 22, 2018: Journal of Clinical Lipidology
Sang-Woong Choi, Hyungseop Kim, In-Cheol Kim, Cheol-Hyun Lee, Jongmin Hwang, Hyoung-Seob Park, Yun-Kyeong Cho, Hyuck-Jun Yoon, Chang-Wook Nam, Seongwook Han, Seung-Ho Hur
PURPOSE: Ultrasonographic contrast enhancement of carotid plaque (CECP) has been used to detect neovascularization of vasa vasorum and plaque. However, it is uncertain whether CECP can provide risk stratification of coronary artery disease (CAD). This study aimed to evaluate the relationship between CECP and manifestations of acute coronary syndrome (ACS) in established CAD patients and to explore the prognostic implication of CECP for cardiovascular (CV) clinical outcomes. METHODS: A medical record review revealed that contrast-enhanced ultrasonography was performed to evaluate carotid atherosclerosis in 209 coronary artery-stented and 105 non-stented patients...
September 2018: Journal of Clinical Ultrasound: JCU
Troy A Webber, Edan A Critchfield, Jason R Soble
To supplement memory-based Performance Validity Tests (PVTs) in identifying noncredible performance, we examined the validity of the two most commonly used nonmemory-based PVTs-Dot Counting Test (DCT) and Wechsler Adult Intelligence Scale-Fourth edition (WAIS-IV) Reliable Digit Span (RDS)-as well as two alternative WAIS-IV Digit Span (DS) subtest PVTs. Examinees completed DCT, WAIS-IV DS, and the following criterion PVTs: Test of Memory Malingering, Word Memory Test, and Word Choice Test. Validity groups were determined by passing 3 (valid; n = 69) or failing ⩾2 (noncredible; n = 30) criterion PVTs...
October 6, 2018: Assessment
Brianna I Katzman, Rita John
BACKGROUND: The psychological distress caused by cancer can remain long after remission. With advanced curative treatments, many pediatric patients continue to have late complications that interfere with neurologic, physical, and social development. OBJECTIVES: The aim of this article is to analyze nine published articles that focus on adolescent cancer survivors (ACSs) and the incidence and risk factors of post-traumatic stress disorder (PTSD) and post-traumatic stress symptoms (PTSSs)...
October 1, 2018: Clinical Journal of Oncology Nursing
Tian Xiao Zhao, Michalis Kostapanos, Charmaine Griffiths, Emma L Arbon, Annette Hubsch, Fotini Kaloyirou, Joanna Helmy, Stephen P Hoole, James H F Rudd, Graham Wood, Keith Burling, Simon Bond, Joseph Cheriyan, Ziad Mallat
INTRODUCTION: Inflammation and dysregulated immune responses play a crucial role in atherosclerosis, underlying ischaemic heart disease (IHD) and acute coronary syndromes (ACSs). Immune responses are also major determinants of the postischaemic injury in myocardial infarction. Regulatory T cells (CD4+ CD25+ FOXP3+ ; Treg) induce immune tolerance and preserve immune homeostasis. Recent in vivo studies suggested that low-dose interleukin-2 (IL-2) can increase Treg cell numbers. Aldesleukin is a human recombinant form of IL-2 that has been used therapeutically in several autoimmune diseases...
September 17, 2018: BMJ Open
Jean-Baptiste Renault, Gaëtan Aüllo-Rasser, Mathias Donnez, Sébastien Parratte, Patrick Chabrand
Increasing use of patient-specific surgical procedures in orthopaedics means that patient-specific anatomical coordinate systems (ACSs) need to be determined. For knee bones, automatic algorithms constructing ACSs exist and are assumed to be more reliable than manual methods, although both approaches are based on non-unique numerical reconstructions of true bone geometries. Furthermore, determining the best algorithms is difficult, as algorithms are evaluated on different datasets. Thus, in this study, we developed 3 algorithms, each with 3 variants, and compared them with 5 from the literature on a dataset comprising 24 lower-limb CT-scans...
August 30, 2018: Journal of Biomechanics
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