keyword
https://read.qxmd.com/read/37650161/-a-control-study-of-steroid-withdrawal-protection-strategy-after-kidney-transplantation-in-children
#21
JOURNAL ARTICLE
J Y Lu, M Zhang, J A Lin, H R Chen, Y J Li, X Gao, C X Wang, L S Liu, X Liao
Objective: To study the influence of steroid withdrawal protection strategy on height growth in pediatric patients after kidney transplantation. Methods: The prospective cohort study enrolled 40 stage 5 chronic kidney disease children receiving kidney transplantation from July 2017 to September 2022 at Guangzhou Women and Children's Medical Center. Based on the primary preoperative disease, patients with immune abnormality-associated glomerular diseases or unknown causes were assigned to the steroid maintenance group, in which patients received steroid tapering within 3 months after surgery to a maintenance dose of 2...
September 2, 2023: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
https://read.qxmd.com/read/37550774/prehabilitation-for-frail-patients-undergoing-total-hip-or-knee-replacement-protocol-for-the-joint-prep-feasibility-randomised-controlled-trial
#22
JOURNAL ARTICLE
Tanzeela Khalid, Yoav Ben-Shlomo, Wendy Bertram, Lucy Culliford, Clare England, Emily Henderson, Catherine Jameson, Marcus Jepson, Shea Palmer, Michael R Whitehouse, Vikki Wylde
BACKGROUND: Approximately, 8% of community-based adults aged ≥ 50 years in England are frail. Frailty has been found to be associated with poorer outcomes after joint replacement. Targeting frailty preoperatively via exercise and protein supplementation has the potential to improve outcomes for people undergoing joint replacement. Prior to proceeding with a randomised controlled trial (RCT), a feasibility study is necessary to address key uncertainties and explore how to optimise trial design and delivery...
August 7, 2023: Pilot and Feasibility Studies
https://read.qxmd.com/read/37519822/neoadjuvant-nivolumab-and-cabozantinib-in-advanced-renal-cell-carcinoma-in-a-horseshoe-kidney-how-to-achieve-a-safe-and-radical-resection-a-case-report-and-review-of-the-literature
#23
Anezka Zemankova, Hana Studentova, Andrea Kopova, Tomas Tichy, Vladimir Student, Bohuslav Melichar
INTRODUCTION: Neoadjuvant nivolumab and cabozantinib in locally advanced renal cell carcinoma in a horseshoe kidney is a novel therapeutic approach in the preoperative setting. METHODS: We report a case of a 52-year old male who presented with a large inoperable tumor of the horseshoe kidney and achieved major partial radiologic response after neoadjuvant therapy with nivolumab and cabozantinib leading to radical resection of the tumor. The patient remains tumor free on the subsequent follow-up and his renal function is only mildly decreased...
2023: Frontiers in Oncology
https://read.qxmd.com/read/37510872/bleeding-disorders-and-dental-implants-review-and-clinical-indications
#24
REVIEW
Christian Bacci, Claudia Schiazzano, Ezio Zanon, Edoardo Stellini, Luca Sbricoli
BACKGROUND: Bleeding disorders can be divided into three categories: congenital coagulation disorders (CCDs), antiplatelet-induced bleeding disorders (APBDs) and anticoagulant-induced bleeding disorders (ACBDs). Implant placement can be challenging in these kinds of patients. The aim of this study is to provide evidence on implant surgery in patients with bleeding disorders and to generate some practical recommendations for clinicians. MATERIAL AND METHODS: Pubmed/MEDLINE, Scopus, Web of Science and Cochrane Library databases were screened...
July 18, 2023: Journal of Clinical Medicine
https://read.qxmd.com/read/37423088/contralateral-transfalcine-approach-for-resection-of-right-medial-frontal-avm
#25
Matthew Z Sun, Eva M Wu, Meredith C Costello, Ahmed Abdelsalam, Robert M Starke, Jacques J Morcos
Brain arteriovenous malformations (AVMs) are high flow vascular lesions that can cause significant morbidity and mortality [1-6]. We present a case of a 23-year-old woman who initially presented to an outside institution with a ruptured right medial frontal Spetzler Martin grade II AVM. An EVD was placed and a diagnostic angiogram with partial embolization was performed. She was then transferred to our institution two months post rupture for further care. On arrival, she was trached with eyes opening to voice and localizing in bilateral upper extremities and withdrawing in bilateral lower extremities...
June 23, 2023: Clinical Neurology and Neurosurgery
https://read.qxmd.com/read/37407040/vitamin-insufficiency-after-surgery-for-oesophagogastric-neoplasms-a-study-protocol-for-a-prospective-intervention-study
#26
JOURNAL ARTICLE
Ariadne L van der Velden, Thomas A Vermeer, Evert-Jan G Boerma, Eric Hj Belgers, Jan Hmb Stoot, Mathie Pg Leers, Meindert N Sosef, Guy Hej Vijgen
INTRODUCTION: Oesophageal cancer (EC) and gastric cancer (GC) are among the top 10 cancers worldwide. Both diseases impact the nutritional status of patients and their Quality of Life (QoL). Preoperative malnutrition is reported in 42%-80%. However, studies investigating postoperative nutritional status are limited, and postoperative identification and treatment of micronutrient and macronutrient deficiencies are currently lacking in (inter-)national guidelines. The aim of this study is to identify and target micronutrient deficiencies after surgery for oesophagogastric neoplasms...
July 4, 2023: BMJ Open
https://read.qxmd.com/read/37369848/the-use-of-anti-adrenergic-agents-as-a-predictor-of-acute-kidney-injury-and-delayed-recovery-of-kidney-function-the-nara-aki-cohort-study
#27
JOURNAL ARTICLE
Masatoshi Nishimoto, Miho Murashima, Maiko Kokubu, Masaru Matsui, Masahiro Eriguchi, Ken-Ichi Samejima, Yasuhiro Akai, Kazuhiko Tsuruya
Association of preoperative regular use of anti-adrenergic agents with postoperative acute kidney injury (AKI) and with trajectory of kidney function after AKI is still unknown. In a retrospective cohort study, adults undergoing non-cardiac surgery under general anesthesia were included. Obstetric or urological surgery, missing data, or preoperative dialysis was excluded. The exposure of interest was preoperative regular use of anti-adrenergic agents. The outcomes were AKI within 1 week postoperatively and trajectories of kidney function within 2 weeks postoperatively among patients with AKI...
June 27, 2023: Hypertension Research: Official Journal of the Japanese Society of Hypertension
https://read.qxmd.com/read/37351557/descending-control-of-nociception-poorly-predicts-the-development-of-persistent-postsurgical-pain-like-behavior-in-consomic-dahl-s-rat-strains
#28
JOURNAL ARTICLE
Luiz F Ferrari, Ashley Wilkinson, Christian Cahoon, Anna Ramirez, Charles Rey, Gary W Donaldson, Norman E Taylor
BACKGROUND: Chronic postsurgical pain is a poorly recognized outcome of surgery where patients experience pain long after healing from the surgical insult. Descending control of nociception, a phenomenon whereby application of a strong nociceptive stimulus to one part of the body of animals inhibits pain in remote body regions, offers one strategy to identify a propensity to develop chronic postsurgical pain-like behavior. Here, consomic rat panel was used to test the hypothesis that pain persistence is mechanistically linked to ineffective descending control of nociception...
October 1, 2023: Anesthesiology
https://read.qxmd.com/read/37291959/considerations-for-perioperative-opioid-analgesic-stewardship-in-australia-a-focus-on-tapentadol
#29
REVIEW
Stephanie C Ternel Lebret
Opioid-related harm remains a serious public health issue in Australia, where there is a strong focus on judicious use of opioids to optimize postoperative patient outcomes. The risks associated with preoperative opioid use (worsened postoperative pain, surgical outcomes, increased length of stay and financial costs) must be balanced with the risks of sub-optimal post-surgical pain management (development of chronic pain, persistent postsurgical opioid use and opioid dependence). In addition to significantly lower rates of gastrointestinal adverse effects (nausea, vomiting, constipation), tapendatol (vs oxycodone) is less likely to cause excessive sedation and opioid-induced ventilatory impairment, may be associated with less withdrawal symptoms of mild to moderate intensity and significantly lower odds of 3-month persistent postoperative opioid use in certain patient populations...
May 2023: Pain Management
https://read.qxmd.com/read/37219585/enhanced-recovery-management-in-pediatric-pyeloplasty-outcomes-in-a-single-institution-and-tips-for-improvement
#30
JOURNAL ARTICLE
Jiannan He, Huajian Lai, Tianyou Zhang, Lei Ye, Bing Yao, Hu Qu, Bo Ma, Qiang Guo, Yifei Zhang, Jianguang Qiu, Dejuan Wang
OBJECTIVE: We report the application of enhanced recovery after surgery (ERAS) regimens to pediatric patients undergoing laparoscopic pyeloplasty (LP), aiming to guide the practice of ERAS in pediatric LP. METHODS: From October 2018, we prospectively implemented a twenty-point ERAS regimen, including a modified LP procedure, for pediatric UPJO patients in a single institution. Data from 2018 to 2021 were collected and analyzed retrospectively. The variables gathered included: demographics, preoperative details and recovery elements...
May 23, 2023: World Journal of Urology
https://read.qxmd.com/read/37211934/-causes-of-asymptomatic-side-limb-pain-after-minimally-invasive-transforaminal-lumbar-interbody-fusion
#31
JOURNAL ARTICLE
You Lyu, Chao Zhang, Dong Zhang
OBJECTIVE: To investigate possible causes and preventive measures for asymptomatic pain in the limbs after minimally invasive transforaminal lumbar interbody fusion(MIS-TLIF). METHODS: Clinical data from 50 patients with lumbar degenerative disease who underwent MIS-TLIF between January 2019 and September 2020 were retrospectively analyzed. The group included 29 males and 21 females aged from 33 to 72 years old, with an average age of (65.3±7.13) years. Twenty-two patients underwent unilateral decompression, and 28 underwent bilateral decompression...
May 25, 2023: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
https://read.qxmd.com/read/37203222/an-individualised-tapering-protocol-reduces-opioid-use-1%C3%A2-year-after-spine-surgery-a-randomised-controlled-trial-of-patients-with-preoperative-opioid-use
#32
JOURNAL ARTICLE
Peter Gaarsdal Uhrbrand, Mikkel Mylius Rasmussen, Simon Haroutounian, Lone Nikolajsen
BACKGROUND: Persistent opioid use following surgery is common especially in patients with preoperative opioid use. This study aims to determine the long-term effect of an individualised opioid tapering plan versus standard of care in patients with a preoperative opioid use undergoing spine surgery at Aarhus University Hospital, Denmark. METHODS: This is the 1-year follow-up of a prospective, single-centre, randomised trial of 110 patients who underwent elective spine surgery for degenerative disease...
September 2023: Acta Anaesthesiologica Scandinavica
https://read.qxmd.com/read/37086001/split-transfer-of-the-tibialis-anterior-tendon-combined-with-calcaneocuboid-fusion-vs-split-transfer-of-the-tibialis-anterior-tendon-alone-to-treat-equinovarus-foot-deformity-in-children-with-cerebral-palsy
#33
JOURNAL ARTICLE
Tayfun Bacaksız, İhsan Akan, Cemal Kazimoglu
BACKGROUND: The study aimed to compare the outcomes of combined calcaneocuboid arthrodesis and split anterior tibialis tendon transfer (SPLATT) procedure to isolated SPLATT surgery for the treatment of the spastic equinovarus deformity in children with cerebral palsy (CCP). METHODS: Forty-one ambulatory CCP with 56 equinovarus feet, with positive flexor withdrawal reflex test results, were studied. The average age was 9.1 ± 3.2 years (range 3-22)...
April 21, 2023: Foot & Ankle International
https://read.qxmd.com/read/37061688/effect-of-acuity-level-and-patient-characteristics-on-bowel-preparation-quality-a-retrospective-cohort-study-of-inpatient-colonoscopies
#34
JOURNAL ARTICLE
Christopher Kabir, Mariani Salazar Leon, Cindy Ndiaye, Michael Flicker
BACKGROUND AND AIMS: Colonoscopy is the primary method to detect mucosal abnormalities in the colon, rectum, and terminal ileum. Inadequate bowel preparation is a common problem and can impede successful visualization during colonoscopy. Although studies identified hospitalization as a predictor of inadequate bowel preparation, acuity of care vary greatly within this patient population. The current study aims to examine the effect of patient characteristics and care level predictors on inadequate bowel preparation quality within the inpatient setting...
April 15, 2023: BMC Gastroenterology
https://read.qxmd.com/read/36971260/low-grade-inflammation-during-the-glucocorticoid-withdrawal-phase-in-patients-with-cushing-s-syndrome
#35
JOURNAL ARTICLE
Frederick Vogel, Leah Braun, Stephanie Zopp, Elisabeth Nowak, Jochen Schreiner, Irina Benz, German Rubinstein, Heike Künzel, Katrin Ritzel, Matthias Kroiss, Jürgen Honegger, Felix Beuschlein, Katharina Schilbach, Daniel Teupser, Martin Bidlingmaier, Martin Reincke
CONTEXT: Endogenous Cushing's syndrome (CS) leads to profound immunosuppression. Successful surgery induces biochemical remission and reversal of immunosuppression, which is characterized by clinical signs of glucocorticoid withdrawal and associated with increased susceptibility to infections and thromboembolic complications. OBJECTIVE: We hypothesized that the glucocorticoid withdrawal phase is characterized by low-grade inflammation that may be related to patient-relevant outcomes...
March 27, 2023: European Journal of Endocrinology
https://read.qxmd.com/read/36920674/conversion-surgery-after-lenvatinib-treatment-for-anaplastic-thyroid-carcinoma-a-case-report
#36
JOURNAL ARTICLE
Haruhiko Yamazaki, Katsuhiko Masudo, Sachie Kanada, Yoshiaki Inayama, Hiroyuki Hayashi, Yu Fujii, Yasushi Rino
BACKGROUND: Anaplastic thyroid carcinoma (ATC) is the most aggressive form of thyroid carcinoma. Lenvatinib, a multikinase inhibitor, is rarely used in preoperative settings due to adverse effects including delayed wound healing and fistula formation. Herein, we report the use of lenvatinib treatment prior to conversion surgery for the treatment of ATC. CASE PRESENTATION: A 71-year-old woman was referred to our hospital with suspected thyroid cancer with recurrent laryngeal nerve invasion and cervical lymph node metastasis based on the results of ultrasonography...
March 15, 2023: Surgical Case Reports
https://read.qxmd.com/read/36794133/chest-tube-free-video-assisted-thoracoscopic-surgery-secured-by-quantitative-air-leak-monitoring-a-case-series
#37
JOURNAL ARTICLE
Qiuyuan Li, Yan Jiang, Junrong Ding, Huan Li, Weidong Zhang, Hongrui Chen, Hanqiao Xu, Zhaoqiang Xia, Liang Duan, Lei Lin
BACKGROUND: Although chest tube-omitted video-assisted thoracoscopic surgery (VATS) has been proven to be safe and efficacious, its universal application is precluded by a varying morbidity rate due to a lack of standardization. Since digital chest drainage has already shown improved accuracy and consistency in the management of postoperative air leak, we incorporated it in the strategy of intraoperative chest tube withdrawal, aiming to achieve better results. METHODS: We collected the clinical data of 114 consecutive patients who underwent elective uniportal VATS pulmonary wedge resection at the Shanghai Pulmonary Hospital from May 2021 to February 2022...
January 31, 2023: Journal of Thoracic Disease
https://read.qxmd.com/read/36792181/ccl17-blockade-by-ccl17mab-gsk-j4-ameliorates-hyperalgesia-in-a-rat-model-of-postoperative-pain
#38
JOURNAL ARTICLE
Zhiyu Zhang, Tian Zhang, Yijia Zhang, Yingxia Liang
CCL17 (C-C motif chemokine ligand 17), an important chemokine, plays a vital role in regulating immune balance in the central nervous system. In this study, we explored the potential roles of CCL17 in a rat postoperative pain model and that of blocking CCL17 in the prevention of postoperative pain in rats. A right plantar incision in rat was used as a model of postoperative pain. A behavioral change was measured preoperatively and postoperatively using mechanical withdrawal thresholds and thermal withdrawal latency...
February 15, 2023: Biological & Pharmaceutical Bulletin
https://read.qxmd.com/read/36689143/reasons-for-preoperative-patient-attrition-among-bariatric-surgery-candidates-patients-point-of-view
#39
JOURNAL ARTICLE
Foolad Eghbali, Fatemeh Jahanshahi, Kiana Garakani, Sevil Ghasemi, Aisa Talebi, Bahador Oshidari, Hesam Mosavari, Abdolreza Pazouki
PURPOSE: Obesity has become a global health concern, associated with decreased quality of life and life expectancy. Although bariatric surgery has many benefits (e.g., substantial and durable weight loss, amelioration of comorbidities, and improvement in functionality), its patient attrition rate is relatively high. Therefore, we aim to assess the causes of withdrawal from our program. MATERIALS AND METHODS: We interviewed patients who dropped out of our bariatric surgery program between January 2016 and December 2021...
January 23, 2023: Obesity Surgery
https://read.qxmd.com/read/36689033/high-preoperative-serum-strontium-levels-increase-the-risk-of-acute-kidney-injury-after-cardiopulmonary-bypass
#40
JOURNAL ARTICLE
Natsumi Tomita, Yuji Hotta, Hidekazu Ito, Aya Naiki-Ito, Karin Matsuta, Yuko Yamamoto, Kazuki Ohashi, Tomoaki Hayakawa, Akimasa Sanagawa, Yasuhiro Horita, Masahiro Kondo, Tomoya Kataoka, Satoru Takahashi, Kazuya Sobue, Kazunori Kimura
BACKGROUND: Acute kidney injury (AKI) is a common complication of cardiac surgeries. The incidence of AKI after cardiac surgeries using cardiopulmonary bypass (CPB-AKI) is high, emphasizing the need to determine strategies to prevent CPB-AKI. This study investigates the correlation between CPB-AKI and trace metal levels in clinical and animal studies. METHODS: Samples and clinical data were obtained from 74 patients from the Nagoya City University Hospital and Okazaki City Hospital...
January 23, 2023: Clinical and Experimental Nephrology
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