Kriti Gera, Doga Kahramangil, Graeme A Fenton, Daniela Martir, Diana N Rodriguez, Zohaib Ijaz, Rick Y Lin, Sherise C Rogers, Brian H Ramnaraign, Thomas J George, Young-Rock Hong, Steven J Hughes, Ibrahim Nassour, Ilyas Sahin
BACKGROUND: Gallbladder carcinoma (GBC) is a rare, aggressive malignancy comprising 0.5% of gastrointestinal cancers. It has poor survival outcomes due to its insidious onset, lack of standardized screening, and limited therapies. Advanced-stage diagnosis with liver, lymph node, and peritoneal metastasis is common, while bone metastasis is rare. The knowledge on bone metastasis in GBC is limited to case reports and small series, and its clinical significance is largely unexplored. METHODS: The study extracted the demographic and clinical variables of patients with metastatic (M1) gallbladder adenocarcinoma from the Surveillance, Epidemiology, and End Results (SEER) database between 2011 and 2020...
October 19, 2023: Cancers