keyword
https://read.qxmd.com/read/38361356/cinnamic-acid-ameliorates-acetic-acid-induced-inflammatory-response-through-inhibition-of-tlr-4-in-colitis-rat-model
#1
JOURNAL ARTICLE
Zahra Rezaei, Saeideh Momtaz, Pardis Gharazi, Mahban Rahimifard, Maryam Baeeri, Ali Reza Abdollahi, Mohammad Abdollahi, Amirhossein Niknejad, Danial Khayatan, Mohammad Hosein Farzaei, Amir Hossein Abdolghaffari
BACKGROUND: Cinnamic acid, an active compound in cinnamon spp., has anti-inflamatory and antioxidant characteristics and is favorable in managing inflammatory bowel diseases. OBJECTIVE: Evaluate cinnamic acid's effects on colitis in rats. METHODS: To induce colitis in experimental rats, excluding the sham group, a 4% intrarectal solution of acetic acid was administered. The rats were then given oral doses of cinnamic acid at 30, 45, and 90 mg/kg for two days...
January 29, 2024: Anti-inflammatory & Anti-allergy Agents in Medicinal Chemistry
https://read.qxmd.com/read/38310527/serum-level-of-lactadherin-mfge8-in-inflamatory-bowel-disease
#2
JOURNAL ARTICLE
Kamil Kozioł, Danuta Owczarek, Dorota Cibor, Małgorzata Zwolińska-Wcisło
OBJECTIVE: Evaluation of serum lactadherin level, its correlation with disease activity and certain biochemical parameters in IBD patients. METHODS: The study involved adult IBD patients, comprising 50 with ulcerative colitis (UC), 68 with Crohn's disease (CD), and 29 healthy controls. RESULTS: The MFGE8 median concentration was significantly higher in UC versus controls (1914.54 vs. 1392.21; p = 0.017), but not in CD. The median MFGE8 levels in UC and CD patient groups didn't significantly differ...
October 30, 2023: Folia Medica Cracoviensia
https://read.qxmd.com/read/34724688/-medical-and-surgical-management-of-moderate-to-severe-inflamatory-bowel-disease
#3
JOURNAL ARTICLE
Juan Eloy Paredes Méndez, Sonia Irene Junes Pérez, Henry Tomas Vargas Marcacuzco, Paulo Anibal Alosilla Sandoval, Isamar Benyi Gutiérrez Córdova, Jorge Luis Fernández Luque, Eduardo Alvarado Ortiz Blanco
UNLABELLED: The management of inflammatory bowel disease (IBD) is mainly medical, however, more than 70% of patients with Crohn's disease (CD) and 25% with ulcerative colitis (UC) will require surgery during their lifetime. OBJECTIVE: To evaluate medical, surgical management and evolution in patients with moderate-to-severe IBD. MATERIALS AND METHODS: Observational, descriptive, retrospective study from January 2011 to December 2019 in the Gastroenterology Service of the Guillermo Almenara Irigoyen National Hospital, Lima-Peru...
2021: Revista de Gastroenterología del Perú: órgano Oficial de la Sociedad de Gastroenterología del Perú
https://read.qxmd.com/read/33909805/brazilian-ibd-study-group-position-statement-on-sars-cov2-vaccination
#4
JOURNAL ARTICLE
Natália Sousa Freitas Queiroz, Fábio Vieira Teixeira, Caio Cesar Furtado Freire, Marina Pamponet Motta, Marcela Almeida Menezes de Vasconcellos, Liliana Andrade Chebli, Rogerio Saad-Hossne
Mass vaccination offers the best strategy to fight against COVID-19 pandemic, and SARS-CoV2 vaccines are being approved in several countries for emergency use. In Brazil, vaccine approval is expected in the next few days, however potential concerns exist regarding vaccine recommendations for specific populations, such as patients with inflammatory bowel disease (IBD). To address these questions, the Brazilian IBD Study Group (GEDIIB) provides this practical advice with key recommendations about the COVID-19 vaccines in IBD population...
2021: Arquivos de Gastroenterologia
https://read.qxmd.com/read/33845581/tofacitinib-a-useful-option-for-the-treatment-of-pyoderma-gangrenosum-in-an-ulcerative-colitis-patient
#5
LETTER
Pablo Salmón Olavarría, Saioa Rubio Iturria, Óscar Nantes Castillejo
Pyoderma gangrenosum (PG) is a difficult-to-manage ulcero-necrotizing dermatosis associated with inflammatory bowel disease (IBD). In this article, we report a refractory PG in a patient with severe ulcerative colitis (UC) that responded to tofacitinib 10 mg/12 h.
October 2021: Revista Española de Enfermedades Digestivas
https://read.qxmd.com/read/33656063/brazilian-ibd-study-group-position-statement-on-sars-cov2-vaccination
#6
JOURNAL ARTICLE
Natália Sousa Freitas Queiroz, Fábio Vieira Teixeira, Caio Cesar Furtado Freire, Marina Pamponet Motta, Marcela Almeida Menezes de Vasconcellos, Liliana Andrade Chebli, Rogerio Saad-Hossne
Mass vaccination offers the best strategy to fight against COVID-19 pandemic, and SARS-CoV2 vaccines are being approved in several countries for emergency use. In Brazil, vaccine approval is expected in the next few days, however potential concerns exist regarding vaccine recommendations for specific populations, such as patients with inflammatory bowel disease (IBD). To address these questions, the Brazilian IBD Study Group (GEDIIB) provides this practical advice with key recommendations about the COVID-19 vaccines in IBD population...
February 26, 2021: Arquivos de Gastroenterologia
https://read.qxmd.com/read/33169787/chromoendoscopy-with-indigo-carmine-vs-virtual-chromoendoscopy-iscan-1-for-neoplasia-screening-in-patients-with-inflammatory-bowel-disease-a-prospective-randomized-study
#7
RANDOMIZED CONTROLLED TRIAL
Oscar González-Bernardo, Sabino Riestra, Santiago Vivas, Ruth de Francisco, Isabel Pérez-Martínez, Andrés Castaño-García, Víctor Jiménez-Beltrán, Valeria Rollé, Patricio Suárez, Adolfo Suárez
INTRODUCTION: The risk of colon cancer is greater in patients with inflammatory bowel disease (IBD) than in the general population. Chromoendoscopy with dye (CE) is the currently recommended method for detecting dysplasia in screening colonoscopies in IBD patients; however, the role of virtual chromoendoscopy (VC) is not yet well defined. OBJECTIVE: The object of this study was to compare CE and VC with the iSCAN 1 system in the detection of neoplastic lesions in IBD patients...
July 27, 2021: Inflammatory Bowel Diseases
https://read.qxmd.com/read/32942866/chronic-cholestatic-liver-diseases-primary-biliary-cholangitis-and-primary-sclerosing-cholangitis
#8
JOURNAL ARTICLE
Tomáš Fejfar, Tomáš Vaňásek, Petr Hůlek
Cholestasis is defined as hepatocyte and cholangiocyte bile excretion failure or failure of bile transport to the duodenum. Primary biliary cholangitis (PBC) and primary sclerosing cholangitis as chronic progressive cholestatic diseases are the common reasons of chronic cholestasis. Altogether with cholestatic laboratory picture the pruritus, liver osteodystrophy and fatigue are associated symptoms in both diseases. All associated symptoms and complications are needed to be diagnosed and treated early. In case of liver cirrhosis complicatons of accompanied portal hypertension should be treated and liver transplantation must be considered in all those patients...
2020: Vnitr̆ní Lékar̆ství
https://read.qxmd.com/read/29756563/cyclooxygenase-2-inhibitors-as-a-therapeutic-target-in-inflammatory-diseases
#9
REVIEW
Miguel D Ferrer, Carla Busquets-Cortés, Xavier Capó, Silvia Tejada, Josep A Tur, Antoni Pons, Antoni Sureda
Inflammation plays a crucial role in the development of many complex diseases and disorders including autoimmune diseases, metabolic syndrome, neurodegenerative diseases, and cardiovascular pathologies. Prostaglandins play a regulatory role in inflammation. Cyclooxygenases are the main mediators of inflammation by catalyzing the initial step of arachidonic acid metabolism and prostaglandin synthesis. The differential expression of the constitutive isoform COX-1 and the inducible isoform COX-2, and the finding that COX-1 is the major form expressed in the gastrointestinal tract, lead to the search for COX-2-selective inhibitors as anti-inflammatory agents that might diminish the gastrointestinal side effects of traditional non-steroidal anti-inflammatory drugs (NSAIDs)...
2019: Current Medicinal Chemistry
https://read.qxmd.com/read/29307123/the-role-of-diet-in-managing-inflamatory-bowel-disease-affected-dogs-a-retrospective-cohort-study-on-76-cases
#10
JOURNAL ARTICLE
Maria Chiara Marchesi, Cecilia C. Timpano, Sara Busechian, Camillo Pieramati, Fabrizio Rueca
The term inflammatory bowel diseases (IBD) refers to a group of idiopathic, chronic intestinal diseases characterized by a diffuse infiltration of inflammatory cells into the lamina propria of the intestine. The pathogenesis of IBD is unknown. The most common signs described are diarrhoea, vomit, and progressive weight loss. In order to make a definitive diagnosis, though, the presence of inflammatory cells infiltration must be evident on histopathologic analysis. The therapeutic approach has 2 main goals: decrease the inflammatory response and remove possible antigenic sources, such as food components or intestinal microflora...
December 29, 2017: Veterinaria Italiana
https://read.qxmd.com/read/26533501/costs-of-inflamatory-bowel-disease-crohns-disease-and-ulcerative-colitis-in-serbia
#11
JOURNAL ARTICLE
M Kostic, L Djakovic, R Sujic, S Jankovic
No abstract text is available yet for this article.
November 2015: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://read.qxmd.com/read/26031872/-biosimilars-in-inflamatory-bowel-disease-management-and-care
#12
JOURNAL ARTICLE
Iván Guerra, Fernando Bermejo
No abstract text is available yet for this article.
June 2015: Revista Española de Enfermedades Digestivas
https://read.qxmd.com/read/25910306/evaluation-of-increased-subclinical-atherosclerosis-risk-with-carotid-intima-media-thickness-and-pulse-wave-velocity-in-inflamatory-bowel-disease
#13
JOURNAL ARTICLE
Erhan Alkan, Mustafa Serkan Karakaş, Bülent Yıldırım
BACKGROUND/AIMS: A significant increase in accelerated atherosclerosis risk have determined in chronic inflammatory diseases. Recent studies have suggested a pathophysiological link between inflamatory bowel disease (IBD) and atherosclerosis; for which carotid intima-media thickness (CIMT) and pulse wave velocity (PWV) has been considered as an early marker. The aim of this study was to determine the presence of early atherosclerosis in IBD patients without clinically diagnosed cardiovascular disease and any coincident risk factors for atherosclerosis...
December 2014: Turkish Journal of Gastroenterology: the Official Journal of Turkish Society of Gastroenterology
https://read.qxmd.com/read/22253125/surgical-treatment-of-neonates-with-very-low-vlbw-or-extremely-low-elbw-birth-weight
#14
JOURNAL ARTICLE
Ewa Sawicka, Klaudia Zak, Maria Boczar, Barbara Płoska-Urbanek, Dariusz Mydlak, Martyna Woynarowska
UNLABELLED: Progress in perinatology and neonatal intensive care led to surgical treatment of premature infants born with low (<1500 g) and extremely low (<1000 g) birth weight. AIM: Evaluation of surgical treatment in the group of neonates with very low birth weight (<1500 g) and extremely low birth weight (<1000 g). MATERIAL AND METHODS: In the years 2000-2009 in the Department of Paediatric Surgery in the Institute of Mother and Child, 617 neonates underwent surgical treatment, 101 of them (16%) were born with very low or extremely low birth weight...
2011: Medycyna Wieku Rozwojowego
https://read.qxmd.com/read/21812362/-diagnostic-value-of-antineutophil-cytoplasmic-antibodies
#15
REVIEW
Agnieszka Zak-Gołab, Antoni Hrycek, Michał Holecki, Jerzy Chudek
Antineutrophil cytoplasmic antibodies (ANCA) constitute a family of auto-antibodies directed against various components of the neutrophil cytoplasm. The indirect immunofluorecence assays detected three fluorescent staining patterns: cANCA--cytoplasmic; pANCA--perinuclear and aANCA--atypical. Occurence ANCA is mainly associated with Wegener's granulomatosis and vasculitis, but they are also detected in autoimmune diseases (eg. in systemic lupus erythematosus, in rheumathoid arthritis, Sjögren's syndrome, in dermatomyositis) and in inflamatory bowel diseases (Crohn disease, colitis ulcerosa)...
2011: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://read.qxmd.com/read/19794271/comparison-of-mr-enteroclysis-with-colonoscopy-in-crohn-s-disease-first-locust-bean-gum-study-from-turkey
#16
COMPARATIVE STUDY
Burcu Narin, Faik Sungurlu, Aysun Balci, Alper Arman, Oya O Kurdas, Masum Simsek
BACKGROUND/AIM: The aim of this study was to compare magnetic resonance enteroclysis (MRE) findings with those of colonoscopy, using locust bean gum (LBG) as an oral contrast agent in the diagnosis and follow-up of patients with Crohn's disease. MATERIALS AND METHODS: Nine patients with histologically proven Crohn 's disease were enrolled in this study; MRE was performed within a week of colonoscopy. All patients were examined using a 1.5 T MR Scanner after per os administration of 850 mL of a combination of LBG and mannitol...
October 2009: Saudi Journal of Gastroenterology: Official Journal of the Saudi Gastroenterology Association
https://read.qxmd.com/read/19668960/-posterior-scleritis-clinical-features-systemic-association-treatment-and-evolution-of-23-patients
#17
JOURNAL ARTICLE
Danuza de Oliveira Machado, André Luis Land Curi, Thaís Fontes Bessa, Wesley Ribeiro Campos, Fernando Oréfice
PURPOSE: To document the clinical features, systemic association, treatment and evolution of 23 patients with posterior scleritis evaluated in the Uveitis service of the Federal University of Minas Gerais. METHODS: 23 patients were identified with the diagnosis of posterior scleritis. Signals and symptoms, visual acuity, B-mode ultrasonography signals, systemic associations, treatment and evolution were described and analyzed. RESULTS: Sixteen patients were female and seven were male with mean age of 44,7 years...
May 2009: Arquivos Brasileiros de Oftalmologia
https://read.qxmd.com/read/18330942/increased-basolateral-sorting-of-carcinoembryonic-antigen-in-a-polarized-colon-carcinoma-cell-line-after-cholesterol-depletion-implications-for-treatment-of-inflammatory-bowel-disease
#18
JOURNAL ARTICLE
Robert Ehehalt, Markus Krautter, Martin Zorn, Richard Sparla, Joachim Fullekrug, Hasan Kulaksiz, Wolfgang Stremmel
AIM: To investigate a possible increase of basolateral expression of carcinoembryonic antigen (CEA) by interfering with the apical transport machinery, we studied the effect of cholesterol depletion on CEA sorting and secretion. METHODS: Cholesterol depletion was performed in polarized Caco-2 cells using lovastatin and methyl-beta-cyclodextrin. RESULTS: We show that CEA is predominantly expressed and secreted at the apical surface. Reduction of the cholesterol level of the cell by 40%-50% with lovastatin and methyl-beta-cyclodextrin led to a significant change of the apical-to-basolateral transport ratio towards the basolateral membrane...
March 14, 2008: World Journal of Gastroenterology: WJG
https://read.qxmd.com/read/17988050/endoanal-ultrasonography-in-establishing-the-diagnosis-of-fecal-incontinence
#19
JOURNAL ARTICLE
Dj Saranovic, Z Krivokapic, D Masulovic, A Djuric, A Ivanovic, B Dobriserevic, Z Markovic, G Barisic
Visualisation of the rectum, rectoanal junction and adjacent structures is very demanding and challenging both with technical and medical side. Local staging of rectal and anal tumor and perianal neoplasm by conventional and sibgle slice CT or by barium enema study is not so valuable. These methods can not visualise fistulous communication in inflamatory bowel diseases and have not any role in evaluation of fecal incontinence. During last decade, endoscopic ultrasound and magnetic resonance imaging have been recognised as methods of choice in establishing diagnosis of rectal, perirectal, anal and perianal diseases...
2007: Acta Chirurgica Iugoslavica
https://read.qxmd.com/read/15950057/sulphate-respiration-from-hydrogen-in-desulfovibrio-bacteria-a-structural-biology-overview
#20
REVIEW
Pedro M Matias, Inês A C Pereira, Cláudio M Soares, Maria Arménia Carrondo
Sulphate-reducing organisms are widespread in anaerobic enviroments, including the gastrointestinal tract of man and other animals. The study of these bacteria has attracted much attention over the years, due also to the fact that they can have important implications in industry (in biocorrosion and souring of oil and gas deposits), health (in inflamatory bowel diseases) and the environment (bioremediation). The characterization of the various components of the electron transport chain associated with the hydrogen metabolism in Desulfovibrio has generated a large and comprehensive list of studies...
November 2005: Progress in Biophysics and Molecular Biology
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