MedRad

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Endorectal coils (ERCs) are used for acquiring high spatial resolution magnetic resonance (MR) images of the human prostate. The goal of this study is to determine the impact of an expandable versus a rigid ERC on changes in the location and deformation of the prostate gland and subsequently on registering prostate images acquired with and without an ERC. Sagittal and axial T2 weighted MR images were acquired from 25 patients receiving a combined MR imaging/MR spectroscopic imaging staging exam for prostate cancer...

PURPOSE: Understanding the internal dynamics of prostate injections, particularly injection pattern distribution is a key step to developing new therapies for prostate disease that may be best served with a direct injection approach. Due to excellent properties involving liquid contrast agents, MRI can be used for targeting and monitoring of injections into organs and tissues. MATERIALS AND METHODS: Eleven intraprostatic injections were performed in vivo with canines using a custom transrectal guiding and imaging system for use in a standard 1...

PURPOSE: Are implanted central venous port catheters suitable for contrast media pressure (power) injection in computed tomography? MATERIAL AND METHODS: In an in vitro study 100 ml of contrast medium (Ultravist 370, Schering, Berlin, Deutschland) was injected through 20 different port catheter systems using a power injector (Stellant, Medrad, Inianola, USA) with a pressure limit of 325 PSI. The injection rate was increased from 2 ml/s to 10 ml/s in increments of 2 ml/s...

PURPOSE: We determined the acute gastrointestinal (GI), genitourinary (GU), and dermatologic (D) toxicity during dose-escalated three-dimensional conformal radiation therapy (3DCRT). A modified intrarectal balloon (Medrad) was used for prostate gland localization and immobilization. METHODS: Forty-six men with clinical category T1c to T3a, and at least one high-risk feature (PSA >10, Gleason > or =7, or MRI evidence of extracapsular extension or seminal vesical invasion) comprised the study cohort...

PURPOSE: Currently available 4-F and 5-F peripherally inserted central catheters (PICCs) were investigated to evaluate their possible application for contrast medium injection using power injectors. The study was performed using an in vitro model to demonstrate the feasibility of using PICCs for contrast-enhanced diagnostic studies. MATERIALS AND METHODS: An evaluation of 24 catheter versions consisting of 4-F single-lumen and 5-F dual-lumen PICCs from 13 different manufacturers was conducted...

No abstract text is available yet for this article.

PURPOSE: To evaluate the diagnostic accuracy of contrast-enhanced magnetic resonance angiography (CE-MRA) MoBI-trak of peripheral vessels in patients with peripheral vascular disease who were candidates for digital subtraction angiography (DSA). METHODS: Eleven patients underwent CE-MRA with automated table movement (MoBI-trak) using a 1.5 T superconducting magnet (Philips Gyroscan ACS NT) equipped with a Power Trak 6000 gradient. Contrast medium (Gd-DTPA) was administered in two sequential boluses-20 cm(3) at 0...

PURPOSE: To evaluate the usefulness of three-dimensional (3D) gadolinium-enhanced magnetic resonance (MR) venography for evaluation of thoracic central veins. MATERIALS AND METHODS: Over a 4-month period, 14 patients with suspected central venous abnormalities were examined on a 1.5 T scanner (Magnetom Sonata, SIEMENS, Germany) by means of MR venography. A FLASH-3D sequence using the following parameters was employed: TR 1.6 ms, TE 0.6 ms, TA 3.74 s, flip: 15 degrees, slab thickness 110 mm, effective slice thickness: 2...

PURPOSE: Purpose of our study was to determine the feasibility and accuracy of contrast enhanced Turbo-MRA (CE-MRA) in the evaluation of patients with carotid artery stenosis, using a dynamic technique with multiple acquisitions. MATERIAL AND METHODS: 37 patients with suspected carotid artery stenosis were studied with a 1.5 T magnet (Siemens Vision Plus) using, with a neck phased array coil, a dynamic tridimensional T1 weighted spoiled GRE (TR/TE/NEX: 3.8/1.4/1; Matrix = 110 x 160; FOV = 163 x 260 mm TA = 10 seconds for each sequence); 4 consecutive sequences were performed during the same breath hold, acquired after i...

PURPOSE: The aim of this study was to record the flow-rate and to calculate the "iodine delivery rate" (IDR) of contrast media of various viscosities when the contrast media are injected by hand. METHODS: Five different catheters for coronary angiography were tested with the injection system Medrad Mark V Plus. Injections were performed with pressures of 100, 200 and 400 PSI. The contrast media examined were Imeron 350, Imeron 400, Omnipaque 350 and Ultravist 370...

PURPOSE: Using a power injector to applicate Gd-DTPA we found a contrast enhancement of the pyelo-caliceal system even in the native studies, and hence we analysed pitfalls when using power injectors in MRI. MATERIAL AND METHODS: We used a power injector Spectris (MedRad, Maastricht, Netherlands). In vitro artifacts were achieved by the mixture of contrast media and saline solution. We substituted contrast media by red water, NaCl by clear water. RESULTS: Using power injectors in MRI, some pitfalls must be avoided, which can render investigations useless, especially dynamic contrast-enhanced investigations...

INTRODUCTION: We tried to optimize the technique of contrast enhanced MR Angiography (MRA) in the study of the main body arteries. MATERIALS AND METHODS: Fifty volunteers were examined with contrast enhanced MRA with a superconductive magnet at 1.5 T (Signa GE) and 3D SPGR sequences acquired with the following parameters: TR 8.2 +/- 1.3 ms, TE 1.8 +/- 7 ms, FA 60 degrees, MA 128 X 256; the images were acquired on the sagittal or coronal planes. The contrast agent (Gd-DTPA) was injected with MedRad Spectris system, with the bolus technique and the following standard parameters: velocity 1...

PURPOSE: We report our experience in the safe use of power injectors with central and small-gauge peripheral venous access devices for intravenous administration of contrast agent to children undergoing computed tomography (CT) examinations. MATERIALS AND METHODS: We reviewed the medical records of 500 patients randomly selected from the 3121 children who underwent intravenous contrast-enhanced CT examinations at our institution from November 1993 through July 1995...

Each of the authors played a significant role in the design and development of one or more of the Medrad/Intec/Cardiac Pacemakers Inc defibrillators. In so doing, each has contributed to the realization of Dr Mirowski's dream. That tens of thousands of patients have now benefitted from his leadership and that many AICDs will soon be competing in the marketplace is testimony to his truly remarkable vision and persistence.

To assess the influence of viscosity on flow resistance, 4 clinically available contrast media were injected through 12 angiographic catheters of varying dimensions at 20 degrees and 37 degrees C. Seven cc of contrast was injected at a pressure of 200 PSI at 3cc/sec by Medrad Mark IV power injector. The pressure of injection through the manifold was recorded with an electronic pressure transducer. The lowest injection pressure at 37 degrees C occurred with Hexabrix. Differences in contrast media viscosity were apparent with catheters less than 6 French diameter...

Coronary angioplasty (PTCA) using prolonged balloon inflation has obviated emergency coronary bypass surgery in some patients with acute occlusions at the time of PTCA. However, the use of prolonged balloon inflations has not been shown to improve long-term restenosis rates. As an alternative to the passive autoperfusion catheter, we evaluated a hemoperfusion system in which blood was obtained from the side arm of an arterial sheath and infused through the central lumen of standard balloon catheters via a modified Medrad IV pump during balloon inflation...