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F Z Mokrane, L Dercle, O Meyrignac, É Crubézy, H Rousseau, N Telmon, F Dedouit
PURPOSE: Multi-phase postmortem computed tomography angiography (MPMCTA) is a growing technique, which is standardized for adults. Application of this protocol for a children population is not so well defined. Our study aims to adapt the adult's protocol to children, using a porcine model. MATERIAL AND METHODS: Three groups of 18 pigs were studied, with a weight distribution between 4 and 48 kg. Different pump devices were used. Pigs of group I were studied using the Virtangio® machine, whereas pigs of groups II and III were studied using used the Medrad® machine...
September 2018: International Journal of Legal Medicine
Federica Matteucci, Laura Solinas, Valentina Turri, Caterina Donati, Vincenzo D'Errico, Andrea Moretti, David Bianchini, Giovanni Paganelli, Davide Gallegati, Mattia Altini
BACKGROUND: Healthcare providers across Europe are facing an ever-growing demand in clinical PET referrals. Currently, it is estimated that the administration of the PET tracer accounts for approximately 40% of the unitary PET procedure reimbursement (uPETr). Although the cost of PET/CT is highly dependant on the radiopharmaceutical cost itself, little is known about the economical impact of the utilized administration method and the repercussions on staff radiation exposure. Our objective was to evaluate the cost- effectiveness of automatic injection/fractionation system IntegoTM (Bayer HealthCare, MEDRAD Europe, Netherlands) for istaff radiation exposure reduction and to validate its use with 18F-choline (FCH)...
July 7, 2016: Quarterly Journal of Nuclear Medicine and Molecular Imaging
V Leung, A Sastry, T D Woo, H R Jones
AIM: To quantify the dose reduction and ensure that the use of a split-bolus protocol provided sufficient vascular enhancement. MATERIALS AND METHODS: Between 1 January 2014 and 31 May 2014, both split bolus and traditional two-phase scans were performed on a single CT scanner (SOMATOM Definition AS+, Siemens Healthcare) using a two-pump injector (Medrad Stellant). Both protocols used Siemens' proprietary tube current and tube voltage modulation techniques (CARE dose and CARE kV)...
October 2015: Clinical Radiology
Piotr P Buszman, Armando Tellez, Maxwell E Afari, Athanasios Peppas, Gerard B Conditt, Serge D Rousselle, Jennifer C McGregor, Mark Stenoien, Greg L Kaluza, Juan F Granada
OBJECTIVES: This study sought to evaluate vascular drug uptake, distribution and response of second-generation paclitaxel coated balloon (PCB) (Cotavance, MEDRAD Interventional, Indianola, Pennsylvania) and compare it with first-generation technology, containing identical excipient and drug concentration. BACKGROUND: Original PCB technologies displayed a heterogeneous deposition of crystalline paclitaxel-iopromide inside the balloon folds, whereas second-generation PCBs consisted of more homogeneous, circumferential coatings...
August 2013: JACC. Cardiovascular Interventions
(no author information available yet)
The infusion pump component of the Medrad Continuum MR infusion system contains ferromagnetic materials and may be pulled into the MR system's bore if not adequately secured. Users need to be aware that neither the pump nor any other components should be removed from the system within the scan room. Additionally, before bringing the system into the scan room, users should verify that the system is free of damage and that the pump and its mounting bracket are both firmly secured.
September 2011: Health Devices
Krzysztof Milewski, Maxwell Eyram Afari, Armando Tellez, Michael S Aboodi, Jung-Sun Kim, Yanping Cheng, Gerard B Conditt, Jennifer C McGregor, Geng Hua Yi, Mark Stenoien, Dan Langanki, Christian G Krueger, Greg L Kaluza, Juan F Granada
OBJECTIVES: The authors aimed to validate a novel iliofemoral in-stent restenosis (ISR) model for the efficacy evaluation of paclitaxel-coated balloons (PCB) using the familial hypercholesterolemic swine (FHS). BACKGROUND: Most of the validation work regarding PCB technologies has been performed in the coronary territory of juvenile domestic swine. Although invaluable for safety evaluation, this model is not suited for the evaluation of the efficacy of peripheral PCB technologies...
October 2012: JACC. Cardiovascular Interventions
Michela Lecchi, Giovanni Lucignani, Claudio Maioli, Giuseppe Ignelzi, Angelo Del Sole
PURPOSE: In nuclear medicine, radiopharmaceuticals are usually administered in unit doses partitioned from multi-dose vials. The partitioning typically takes place in a radiopharmacy, depending on local practice. Automatic, as opposed to manual, partitioning and administration should reduce radiation exposure of the personnel involved, improve the accuracy of the administration and mitigate contamination. This study set out to verify and validate the (18)F-fluorodeoxyglucose (FDG) administration procedure performed using Intego (MEDRAD, Inc...
November 2012: European Journal of Nuclear Medicine and Molecular Imaging
John M Moriarty, Geoffrey L Kung, Yanerys Ramos, Abbas N Moghaddam, Daniel B Ennis, J Paul Finn
BACKGROUND: Catheter rupture during CT angiography has prompted policies prohibiting the use of electronic injectors with peripherally inserted central venous catheters (PICCs) not only for CT but also for MRI. Consequently, many institutions mandate hand injection for MR angiography, limiting precision of infusion rates and durations of delivery. OBJECTIVE: To determine whether electronic injection of gadolinium-based contrast media through a range of small-caliber, single-lumen PICCs would be safe without risk of catheter rupture over the range of clinical protocols and determine whether programmed flow rates and volumes were realized when using PICCs for contrast delivery...
September 2012: Pediatric Radiology
Melissa Bailey, Gwynne Kirchen, Bridget Bonaventura, Kelly Rosborough, Mahmoud Abdel-Rasoul, Roger Dzwonczyk
Most electrical equipment in the modern operating room (OR) radiates electrical noise (EN) that can interfere with patient monitors. We have described the EN that an intraoperative magnetic resonance imaging (iMRI) system emits and have shown that this high-energy EN diminishes the quality of the ECG waveform during iMRI scans in our neurosurgical OR. We have also shown that the ECG signal filters in our iMRI-compatible patient monitor reduce this interference but, in the process, disturb the true morphology of the displayed waveform...
June 2012: Journal of Clinical Monitoring and Computing
B Schnorr, U Speck, B Scheller
The use of drug-coated balloons (DCB) for preventing restenosis in both coronary and peripheral arteries has received increasing attention. The first successful clinical outcomes in inhibiting restenosis have been reported for paclitaxel-coated balloons. Paclitaxel is a lipophilic substance characterized by rapid intracellular uptake and irreversible binding to microtubules. In this way, paclitaxel alters the cell structure, ultimately reducing proliferation, migration, and signaling. These properties make paclitaxel a very potent antiproliferative drug...
October 2011: Minerva Cardioangiologica
Sisto Perdonà, Giuseppe Di Lorenzo, Riccardo Autorino, Carlo Buonerba, Marco De Sio, Sergio Venanzio Setola, Roberta Fusco, Francesco Michele Ronza, Michele Caraglia, Matteo Ferro, Antonella Petrillo
BACKGROUND: The use of magnetic resonance spectroscopy imaging (MRSI) and dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) have emerged as a valid diagnostic tools for prostate cancer (CaP). METHODS: Men with PSA levels below 10 ng/ml were enrolled in a prospective cohort study and underwent combined MRSI and DCE-MRI and transrectal ultrasound-guided prostate biopsy. Imaging was performed using a 1.5 T MR scanner (Symphony TIM; Siemens, Erlangen, Germany) with an endorectal coil (Medrad; Pittsburg, PA), inflated with 60 cc of air...
August 2013: Urologic Oncology
Karan Garg, Neal Cayne, Glenn Jacobowitz
We report the use of mechanical and pharmacologic catheter-directed thrombolysis in treating deep vein thrombosis with congenital absence of the inferior vena cava The patient presented with disabling bilateral lower extremity swelling and pain and was found to have extensive bilateral iliofemoral deep vein thromboses. Genetic testing revealed a factor V Leiden mutation. The patient underwent thrombolysis using a Possis (MEDRAD Inc, Warrendale, Pa) catheter and overnight infusion of tissue plasminogen activator...
June 2011: Journal of Vascular Surgery
Claude Abdallah, Raafat Hannallah, Kantilal Patel
This study aimed to review the use of two methods of propofol infusion: a metred burette system where propofol is diluted in Lactated Ringer using the rule of six [ 1 ] or an infusion pump: Medrad Continuum Magnetic resonance (MR) compatible Infusion System (Medrad Inc. Indianola, PA) and to determine the difference, if any, between the total amount of drug delivered, the impact on vital signs, sedation status and discharge time of the patients. With Institutional Review Board (IRB) approval, 140 children aged 0 to 18 years, American Society of Anesthesiologists (ASA) physical status I or II requiring sedation for elective outpatient brain Magnetic Resonance Imaging (MRI) examination were included in the study...
October 2010: Journal of Medical Engineering & Technology
Jiachao Liang, Steffen Sammet, Xiangyu Yang, Guang Jia, Yukihisa Takayama, Michael V Knopp
PURPOSE: To compare the intraindividual differences of dynamic signal characteristics for 3 gadolinium chelates (gadopentetate dimeglumine [Gd-DTPA], gadodiamide [Gd-DTPA-BMA], and gadobenate dimeglumine [Gd-BOPTA]) using dynamic contrast enhanced magnetic resonance (MR) imaging (DCE-MRI) with a preclinical beagle model at 7 Tesla. METHOD AND MATERIALS: Seven beagles were scanned 3 times each with a 7-day interval between the scans on a 7T whole body MRI system (Achieva, Philips) using a T/R head coil...
May 2010: Investigative Radiology
Eric Barua, Jeffrey Johnston, Jeffrey Fujii, Roger Dzwonczyk, Ennio Chiocca, Sergio Bergese
The Polestar N-20 Scanner (Medtronic Navigation, Louisville, CO) is an intraoperative magnetic resonance image (iMRI) guidance system designed for neurosurgery. Sixty-five patients underwent craniotomy for tumor resection using the iMRI during the period from April 2005 to December 2006. Anesthesiologists used an iMRI-compatible patient monitoring system (Veris MR, MEDRAD, Indianola, PA), anesthesia machine (Aestiva/5 MRI, Datex-Ohmeda, Madison, WI), and infusion pumps (Continuum; MEDRAD). Average setup time for each case (from intubation to incision) was one hour, 33 minutes and showed learning improvement over the 21-month period...
August 2009: Journal of Clinical Anesthesia
(no author information available yet)
No abstract text is available yet for this article.
May 2007: Health Devices
Yongbok Kim, I-Chow J Hsu, Jean Pouliot, Susan Moyher Noworolski, Daniel B Vigneron, John Kurhanewicz
Endorectal coils (ERCs) are used for acquiring high spatial resolution magnetic resonance (MR) images of the human prostate. The goal of this study is to determine the impact of an expandable versus a rigid ERC on changes in the location and deformation of the prostate gland and subsequently on registering prostate images acquired with and without an ERC. Sagittal and axial T2 weighted MR images were acquired from 25 patients receiving a combined MR imaging/MR spectroscopic imaging staging exam for prostate cancer...
December 2005: Medical Physics
Scott L Chowning, Robert C Susil, Axel Krieger, Gabor Fichtinger, Louis L Whitcomb, Ergin Atalar
PURPOSE: Understanding the internal dynamics of prostate injections, particularly injection pattern distribution is a key step to developing new therapies for prostate disease that may be best served with a direct injection approach. Due to excellent properties involving liquid contrast agents, MRI can be used for targeting and monitoring of injections into organs and tissues. MATERIALS AND METHODS: Eleven intraprostatic injections were performed in vivo with canines using a custom transrectal guiding and imaging system for use in a standard 1...
March 1, 2006: Prostate
B Gebauer, U K-M Teichgräber, T Hothan, R Felix, H-J Wagner
PURPOSE: Are implanted central venous port catheters suitable for contrast media pressure (power) injection in computed tomography? MATERIAL AND METHODS: In an in vitro study 100 ml of contrast medium (Ultravist 370, Schering, Berlin, Deutschland) was injected through 20 different port catheter systems using a power injector (Stellant, Medrad, Inianola, USA) with a pressure limit of 325 PSI. The injection rate was increased from 2 ml/s to 10 ml/s in increments of 2 ml/s...
October 2005: RöFo: Fortschritte Auf Dem Gebiete der Röntgenstrahlen und der Nuklearmedizin
Rosemonde Woel, Clair Beard, Ming-Hui Chen, Mark Hurwitz, Marian Loffredo, Elizabeth McMahon, Jane Ching, Lynn Lopes, Anthony V D'Amico
PURPOSE: We determined the acute gastrointestinal (GI), genitourinary (GU), and dermatologic (D) toxicity during dose-escalated three-dimensional conformal radiation therapy (3DCRT). A modified intrarectal balloon (Medrad) was used for prostate gland localization and immobilization. METHODS: Forty-six men with clinical category T1c to T3a, and at least one high-risk feature (PSA >10, Gleason > or =7, or MRI evidence of extracapsular extension or seminal vesical invasion) comprised the study cohort...
June 1, 2005: International Journal of Radiation Oncology, Biology, Physics
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