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https://read.qxmd.com/read/30759068/identification-of-growth-patterns-of-preterm-and-small-for-gestational-age-children-from-birth-to-4-years-do-they-catch-up
#1
Dirk Manfred Olbertz, Rebekka Mumm, Ursula Wittwer-Backofen, Susanne Fricke-Otto, Anke Pyper, Johannes Otte, Martin Wabitsch, Petra Gottmann, Karl Otfried Schwab, Martin Scholten, Kathrin Gerstmann, Manfred Voigt
Background A legitimate indication for growth hormone (GH) therapy in children born too light or short at birth [small-for-gestational age (SGA)] exists in Germany and the European Union only if special criteria are met. Methods We conducted a longitudinal, multi-centered study on full-term appropriate-for-gestational age (AGA, n=1496) and pre-term born SGA (n=173) and full-term SGA children (n=891) in Germany from 2006 to 2010. We analyzed height, weight, body mass index (BMI) and head circumference. Results Pre-term or full-term born SGA children were shorter, lighter and had a lower BMI from birth until 3 years of age than full-term AGA children...
February 13, 2019: Journal of Perinatal Medicine
https://read.qxmd.com/read/30735437/sex-specific-perinatal-programming-of-adult-insulin-resistance-in-guinea-pigs-by-variable-perinatal-growth-induced-by-spontaneous-variation-in-litter-size
#2
Dane M Horton, David A Saint, Kathryn L Gatford, Karen L Kind, Julie A Owens
Intrauterine growth restriction (IUGR) and subsequent neonatal catch-up growth are implicated in programming of insulin resistance later in life. Spontaneous IUGR in the guinea pig, due to natural variation in litter size, produces offspring with asymmetric IUGR and neonatal catch-up growth. We hypothesized that spontaneous IUGR and/or accelerated neonatal growth would impair insulin sensitivity in adult guinea pigs. Insulin sensitivity of glucose metabolism was determined by hyperinsulinemic-euglycemic clamp (HEC) in 38 (male=21, female=17) young adult guinea pigs from litters of two to four pups...
February 8, 2019: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology
https://read.qxmd.com/read/30715743/growth-impairment-in-individuals-with-citrin-deficiency
#3
Chikahiko Numakura, Gen Tamiya, Masao Ueki, Tomoo Okada, Shun-Ichi Maisawa, Kanako Kojima-Ishii, Jun Murakami, Reiko Horikawa, Daisuke Tokuhara, Koichi Ito, Masanori Adachi, Takahiro Abiko, Tetsuo Mitsui, Kiyoshi Hayasaka
Citrin deficiency causes neonatal intrahepatic cholestasis (NICCD), failure to thrive and dyslipidemia (FTTDCD), and adult-onset type II citrullinemia (CTLN2). Owing to a defect in the NADH-shuttle, citrin deficiency impairs hepatic glycolysis and de novo lipogenesis leading to hepatic energy deficit. To investigate the physiological role of citrin, we studied the growth of 111 NICCD-affected subjects (51 males and 60 females) and 12 NICCD-unaffected subjects (five males and seven females), including the body weight, height, and genotype...
January 9, 2019: Journal of Inherited Metabolic Disease
https://read.qxmd.com/read/30709755/iugr-genetic-influences-metabolic-problems-environmental-associations-triggers-current-and-future-management
#4
REVIEW
Feyza Darendeliler
The children with intrauterine growth restriction (IUGR) especially if they make a catch-up growth in early life have a higher risk for long term problems including short stature and also developing metabolic syndrome, Type 2 diabetes, insulin resistance and cardiovascular diseases. The studies also support that these children may have abnormalities in pubertal timing, adrenarche and reproductive function. The aim of this review was to summarize the published reports mainly on puberty and reproductive functions in children born IUGR at older ages in association with metabolic problems that they encounter...
January 22, 2019: Best Practice & Research. Clinical Endocrinology & Metabolism
https://read.qxmd.com/read/30703154/longitudinal-growth-and-emotional-and-behavioral-problems-at-age-7-in-moderate-and-late-preterms
#5
Baukje M Dotinga, Andrea F de Winter, Inger F A Bocca-Tjeertes, Jorien M Kerstjens, Sijmen A Reijneveld, Arend F Bos
OBJECTIVES: Moderately and late preterm children (MLPs, 32.0-36.9 weeks gestational age) have a greater risk of poorer growth. This seems to be associated with poorer neuropsychological functioning. Evidence is limited on whether this also holds for emotional and behavioral (EB) problems. Therefore, we assessed whether longitudinal growth from birth until age 7 was associated with EB problems at age 7 in MLPs. STUDY DESIGN: This study was part of the Longitudinal Preterm Outcome Project, a prospective cohort study...
2019: PloS One
https://read.qxmd.com/read/30693654/growth-failure-in-focal-dermal-hypoplasia
#6
Stephanie C Hsu, Sarah Bartz, Laura Pyle, Mary Fete, Shanlee Davis, Rebecca Ohman-Hanson, Timothy J Fete, Kathleen J Motil
Focal dermal hypoplasia (FDH) is a rare genetic disorder caused by mutations in the PORCN gene located on the X chromosome. Short stature was previously noted to be a common finding in FDH, however the etiology of this is unclear. The present study sought to elucidate specific causes for short stature by assessing growth charts, determining bone ages and auxologic measurements, examining laboratory data for the common causes of growth failure, assessing dietary intake, and performing a growth hormone stimulation test...
January 28, 2019: American Journal of Medical Genetics. Part A
https://read.qxmd.com/read/30685852/maternal-chronic-intermittent-hypoxia-in-rats-causes-early-atherosclerosis-with-increased-expression-of-caveolin-1-in-offspring
#7
Huihuang Lin, Yiming Zeng, Ziyan Wang
OBJECTIVE: The objective of our research was to explore the effects of maternal and postpartum chronic intermittent hypoxia (CIH) exposure on atherosclerosis in adulthood offspring of rats, and the role of Caveolin-1 in the course. METHODS: Sixteen rats were assigned to two groups (n = 8), maternal normoxia and CIH group. After delivery, two male pups per litter were selected and breastfed for 1 month, which then randomly received postpartum normoxia or CIH...
January 26, 2019: Sleep & Breathing, Schlaf & Atmung
https://read.qxmd.com/read/30678423/isolated-growth-hormone-deficiency-type-ii-due-to-a-novel-gh1-mutation-a-case-report
#8
Ahmad Kautsar, Jan M. Wit, Aman Pulungan
Isolated growth hormone deficiency (IGHD) type II is a rare autosomal dominant disorder characterized by severe short stature with low growth hormone level. Timely diagnosis is important for optimal results of recombinant human GH (rhGH) treatment and detection of additional pituitary deficiencies in affected relatives. A male child presented at the age of one year with severe proportionate short stature (-4.9 SDS) with normal Body Mass Index (-1.1 SDS). Physical examination revealed frontal bossing, midfacial hypoplasia, normal external genitalia with no dysmorphic features...
January 25, 2019: Journal of Clinical Research in Pediatric Endocrinology
https://read.qxmd.com/read/30664741/short-term-antidepressant-treatment-has-long-lasting-effects-and-reverses-stress-induced-decreases-in-bone-features-in-rats
#9
S H Lee, C A Mastronardi, R W Li, G Paz-Filho, E G Dutcher, M D Lewis, A D Vincent, P N Smith, S R Bornstein, J Licinio, M L Wong
Antidepressants are among the most-prescribed class of drugs in the world and though weight gain is a common outcome of antidepressant treatment, that effect is not well understood. We employed an animal model comprised of 2 weeks of chronic restraint stress with antidepressant treatment, followed by diet-induced obesity. We showed that short-term antidepressant treatment had long-lasting effects, not only leading to weight gain, but also enhancing trabecular and cortical bone features in rats; therefore, weight gain in this model was different from that of the classic diet-induced obesity...
January 16, 2019: Translational Psychiatry
https://read.qxmd.com/read/30649167/catch-up-growth-in-full-term-small-for-gestational-age-infants-a-systematic-review
#10
Susan C Campisi, Sarah E Carbone, Stanley Zlotkin
This is the first systematic review to examine the global prevalence of catch-up growth (CUG) in small for gestational age (SGA) infants who were born at full term (FT). Size at birth and subsequent growth is an important indicator of neonatal and adult health. Globally, 16% of infants are SGA at birth, ranging from 7% in industrialized countries to 41.5% in South Asia. SGA infants are at increased risk for negative developmental and adult health outcomes. Some achieve CUG but others do not. CUG has immediate and late health implications especially in low- and middle-income countries...
January 11, 2019: Advances in Nutrition
https://read.qxmd.com/read/30611596/catch-up-growth-and-behavioral-development-among-preterm-small-for-gestational-age-children-a-nationwide-japanese-population-based-study
#11
Akihito Takeuchi, Takashi Yorifuji, Mariko Hattori, Kei Tamai, Kazue Nakamura, Makoto Nakamura, Misao Kageyama, Toshihide Kubo, Tatsuya Ogino, Katsuhiro Kobayashi, Hiroyuki Doi
OBJECTIVE: To examine the relationship between the catch-up growth of preterm, SGA children and their behavioral development. METHODS: We analyzed data from a large Japanese, nationwide, population-based, longitudinal survey that started in 2001. We restricted the study participants to preterm children with information on height at 2 years of age (n = 1667). Catch-up growth for SGA infants was defined as achieving a height at 2 years of age above -2.0 standard deviations for chronological age...
January 2, 2019: Brain & Development
https://read.qxmd.com/read/30606228/postnatal-length-and-weight-growth-velocities-according-to-fenton-reference-and-their-associated-perinatal-factors-in-healthy-late-preterm-infants-during-birth-to-term-corrected-age-an-observational-study
#12
Li Zhang, Yan Li, Shuang Liang, Xiao-Juan Liu, Feng-Ling Kang, Gui-Mei Li
BACKGROUND: Optimum early postnatal growth is critical for early and later health of preterm infants. Postnatal length and weight growth velocities and their associated perinatal factors in healthy late preterm infants without restriction of neonatal complications and nutritional problems have not been widely studied. METHODS: As part of ongoing longitudinal follow-up study of growth and development of preterm infants in Shandong Qianfoshan Hospital in China, 599 healthy late preterm infants without neonatal complications and nutritional problems were sampled from 795 preterm infants born in January 2014 to April 2017...
January 3, 2019: Italian Journal of Pediatrics
https://read.qxmd.com/read/30604693/effects-of-percutaneous-varicocele-repair-on-testicular-volume-results-from-a-12-month-follow-up
#13
Andrea Sansone, Danilo Alunni Fegatelli, Carlotta Pozza, Giorgio Fattorini, Rosa Lauretta, Marianna Minnetti, Francesco Romanelli, Pierleone Lucatelli, Mario Corona, Mario Bezzi, Francesco Lombardo, Andrea Lenzi, Daniele Gianfrilli
Varicocele is a common finding in men. Varicocele correction has been advocated for young patients with testicular hypotrophy, but there is a lack of morphofunctional follow-up data. We assessed whether percutaneous treatment of left varicocele is associated with testicular "catch-up growth" in the following 12 months by retrospectively reviewing data from an electronic database of 10 656 patients followed up in our clinic between 2006 and 2016. We selected all young adults (<35 years) with left varicocele who underwent percutaneous treatment, had a minimum of 12 months' ultrasound imaging follow-up, and had no other conditions affecting testicular volume...
December 25, 2018: Asian Journal of Andrology
https://read.qxmd.com/read/30598443/nutrition-the-visceral-immune-system-and-the-evolutionary-origins-of-pathogenic-obesity
#14
Mary Jane West-Eberhard
The global obesity epidemic is the subject of an immense, diversely specialized research effort. An evolutionary analysis reveals connections among disparate findings, starting with two well-documented facts: Obesity-associated illnesses (e.g., type-2 diabetes and cardiovascular disease), are especially common in: ( i ) adults with abdominal obesity, especially enlargement of visceral adipose tissue (VAT), a tissue with important immune functions; and ( ii ) individuals with poor fetal nutrition whose nutritional input increases later in life...
January 15, 2019: Proceedings of the National Academy of Sciences of the United States of America
https://read.qxmd.com/read/30587647/growth-patterns-in-small-for-gestational-age-babies-and-correlation-with-insulin-like-growth-factor-1-levels
#15
Deepika Rustogi, Sangeeta Yadav, Siddarth Ramji, T K Mishra
OBJECTIVE: Correlation of catch-up growth and Insulin-like Growth Factor -1 levels (IGF-I) in SGA babies. METHODS: 50 Full-term Small for Gestational Age children aged 12-18 months were analyzed for Catch-up growth (gain in weight and/or length, Standard Deviation Score/SDS >0.67). IGF-1 was measured after post-glucose load using ELISA method and correlated with catch-up growth. RESULTS: Mean (SD) birthweight and length were 2.1 (0.3) Kg and 44...
November 15, 2018: Indian Pediatrics
https://read.qxmd.com/read/30585805/nutritional-support-in-the-recovery-phase-of-critically-ill-children
#16
Koen F M Joosten, Renate D Eveleens, Sascha C A T Verbruggen
PURPOSE OF REVIEW: The metabolic stress response of a critically ill child evolves over time and thus it seems reasonable that nutritional requirements change during their course of illness as well. This review proposes strategies and considerations for nutritional support during the recovery phase to gain optimal (catch-up) growth with preservation of lean body mass. RECENT FINDINGS: Critical illness impairs nutritional status, muscle mass and function, and neurocognition, but early and high intakes of artificial nutrition during the acute phase cannot resolve this...
March 2019: Current Opinion in Clinical Nutrition and Metabolic Care
https://read.qxmd.com/read/30573000/-research-advances-in-the-relationship-between-iron-deficiency-and-neurodevelopment-in-preterm-infants
#17
Lin Xu, Ming-Yan Li, Yue-Liang Shen
Iron deficiency (ID) is the most common micronutrient deficiency in children. Due to insufficient iron storage at birth and rapid catch-up growth after birth, preterm infants tend to have a high incidence rate of ID. During the critical period of brain development, ID alters iron-dependent neurometabolism, neurochemistry, neuroanatomy, and gene/protein profiles. This affects the central nervous system and causes the change in neurocognitive and behavioral development. Iron supplementation in infancy cannot reverse neurodevelopmental impairment caused by perinatal ID...
December 2018: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
https://read.qxmd.com/read/30559857/-igf1r-gene-alterations-in-children-born-small-for-gestitional-age-sga
#18
Aleksandra Janchevska, Marina Krstevska-Konstantinova, Heike Pfäffle, Marina Schlicke, Nevenka Laban, Velibor Tasic, Zoran Gucev, Kristina Mironska, Aleksandar Dimovski, Jürgen Kratzsch, Jürgen Klammt, Roland Pfäffle
BACKGROUND: Small for gestational age (SGA)-born children are a heterogeneous group with few genetic causes reported. Genetic alterations in the IGF1 receptor (IGF1R) are found in some SGA children. AIM: To investigate whether alterations in IGF1R gene are present in SGA born children. PATIENTS AND METHODS: We analysed 64 children born SGA who stayed short (mean -3.25 ± 0.9 SDS) within the first 4 years of age, and 36 SGA children who caught up growth (0...
November 25, 2018: Open Access Macedonian Journal of Medical Sciences
https://read.qxmd.com/read/30557361/reduced-body-weight-at-weaning-followed-by-increased-post-weaning-growth-rate-interacts-with-part-per-trillion-fetal-serum-concentrations-of-bisphenol-a-bpa-to-impair-glucose-tolerance-in-male-mice
#19
Julia A Taylor, Jennifer M Sommerfeld-Sager, Chun-Xia Meng, Susan C Nagel, Toshi Shioda, Frederick S Vom Saal
There is evidence from longitudinal studies that being light at birth and weaning is associated with subsequent rapid weight gain in infants. This is referred to as "centile crossing", which can lead to increased risk of lifetime obesity, glucose dysregulation and type 2 diabetes. Here, pregnant CD-1 mice were hemi-ovariectomized so that the entire litter was contained in one uterine horn to increase variability in fetal growth rate. Pregnant females were implanted on gestation day (GD) 9 with a Silastic capsule containing 6, 60 or 600 μg bisphenol A (BPA)...
2018: PloS One
https://read.qxmd.com/read/30555169/immigrants-economic-assimilation-evidence-from-longitudinal-earnings-records
#20
Andrés Villarreal, Christopher R Tamborini
We examine immigrants' earnings trajectories, and measure both the extent and speed with which they are able to reduce the earnings gap with natives, using a unique dataset that links respondents of the Survey of Income and Program Participation (SIPP) to their longitudinal earnings obtained from individual tax records. Our analysis addresses key debates regarding ethnoracial and cohort differences in immigrants' earnings trajectories. First, we find a racially-differentiated pattern of earnings assimilation whereby black and Hispanic immigrants are less able to catch up with native whites' earnings compared to white and Asian immigrants, but are able to almost reach earnings parity with natives of their same race and ethnicity...
August 1, 2018: American Sociological Review
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