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Bhavana Patel, Shubhangi B Kamble, Hitesh A Vyas, Mahesh K Vyas, Rajkumar Chinthala
An elevated total or low-density lipoprotein (LDL) cholesterol levels or low levels of high-density lipoprotein (HDL) cholesterol is defined as dyslipidemia which is an important risk factor for coronary artery diseases (CADs) and strokes. It is estimated that abnormal cholesterol levels in the blood lead to cause about 18% of cardio vascular diseases (CVDs) and 56% of the ischemic heart diseases at global level. In comparison with others, South Asians have the highest incidence rate of CADs. Acharya Charaka has mentioned Rukshana Upakrama (a type of management which induces dryness) as one amongst the Shad-Upakrama (six principles of management) and can be considered as the best for the reduction of increased Kapha Dosha, Meda Dhatu (adipose tissue) and their related morbid factors...
April 2018: Ayu
Juan Tovar-Huamani, Felipe Mercado-Olivares, Jose Antonio Grandez-Urbina, Rafael Pichardo-Rodriguez, Marco Tovar-Huamani, Herney García-Perdomo
OBJECTIVE: This PUBA study aimed to assess the efficacy of fractional CO2 laser in the treatment of genitourinary syndrome of menopause (GSM). METHODS: GSM symptoms were assessed before, 1 month after the first session and 1 month after the third session of laser (3 sessions with a 30 days interval between them) in 60 women (median, interquartile range: 55, 49-69). Subjective (visual analog scale) and objective (Vaginal Health Index, VHIS; Vaginal Maturity Index/Frost Index; Spanish Overactive Bladder Questionnaire-Short Form, USMEX Spanish OAB-qSF and Female Sexual Function Index, FSFI) measures were used during the study period to assess CO2 fractionated laser treatment outcomes compared to baseline...
February 19, 2019: Lasers in Surgery and Medicine
Justyna Kozłowska, Weronika Prus, Natalia Stachowiak
Most peeling products (exfoliators) available on the market, used in cosmetic and aesthetic dermatology applications, contain synthetic microbeads as abrasive agents. After being released into the natural environment, these non-biodegradable microparticles have an adverse impact on it, especially on aquatic ecosystems. Cosmetics consisting of solid plastic particles will be prohibited in the European Union from 2020. Therefore, there is a great need to develop effective abrasive substances for cosmetic industry...
February 15, 2019: International Journal of Biological Macromolecules
Elizabeth J Price, Alan N Baer
SS is a chronic, autoimmune disease of unknown aetiology for which there is no known curative treatment. Although dryness of the eyes and mouth are the classically described features, patients often experience drying of other mucosal surfaces and systemic manifestations, including fatigue and arthralgia. There is an association with other autoimmune diseases, especially thyroid disease, coeliac disease and primary biliary cholangitis. Systemic features may affect up to 70% and include inflammatory arthritis, skin involvement, haematological abnormalities, neuropathies, interstitial lung disease and a 5-10% lifetime risk of B cell lymphoma...
February 15, 2019: Rheumatology
Iris L A Bodewes, Albin Björk, Marjan A Versnel, Marie Wahren-Herlenius
Primary SS (pSS) is a rheumatic disease characterized by an immune-mediated exocrinopathy, resulting in severe dryness of eyes and mouth. Systemic symptoms include fatigue and joint pain and a subset of patients develop more severe disease with multi-organ involvement. Accumulating evidence points to involvement of innate immunity and aberrant activity of the type I IFN system in both the initiation and propagation of this disease. Analysis of the activity of IFN-inducible genes has evidenced that more than half of pSS patients present with a so-called 'type I IFN signature'...
February 15, 2019: Rheumatology
Muhammad Amir Bakhtavar, Irfan Afzal, Shahzad Maqsood Ahmed Basra
Seed moisture content (SMC) is an important attribute to seed quality. Maintaining seed dryness throughout supply chain (The Dry Chain) prevents seed germination and quality losses. Ambient relative humidity (RH) and temperature affect seed moisture and thereof seed moisture isotherm. Present study was conducted to compare the moisture adsorption isotherms of wheat, maize, cotton and quinoa seeds packed in hermetic Super Bag and traditional packaging materials including paper, polypropylene (PP), jute and cloth bags...
2019: PloS One
Xiaoyu Zeng, Ying Lv, Zhongxiu Gu, Zhe Jia, Chen Zhang, Xiaoxiao Lu, Chenchen Chu, Yichen Gao, Yu Nie, Yanxia Wang, Yan Zhang, Shaozhen Zhao
Purpose: To observe ocular surface changes in Type II diabetic patients with different disease durations and to understand the correlations between clinical parameters and diabetic durations. Methods: In this cross-sectional, prospective study, 51 healthy controls and 91 patients with Type II diabetes were enrolled. The diabetics were divided into 3 subgroups according to the disease duration, including duration <10 y group, 10 to 20 y group, and ≥21 y group...
2019: Journal of Ophthalmology
Jadwiga Wańczyk-Baszak, Sławomir Woźniak, Bartosz Milejski, Tomasz Paszkowski
Perimenopausal changes caused by oestrogen deficiency are accompanied by a decrease in the content of collagen and elastin in the tissues, leading to thinning of the epithelium and the resultant disappearance of the superficial layer, which leads to smooth muscle dysfunction as well as connective tissue degradation. This aetiopathogenetic chain results in a set of symptoms experienced by approximately 50% of women in the peri- and postmenopausal period. Symptoms of dryness, burning, dyspareunia and urgency contribute to a significant reduction in the quality of sexual function and general comfort of life due to recurrent infections of the vagina, vulva and urinary tract...
December 2018: Przeglad Menopauzalny, Menopause Review
Ana Lúcia Gonçalves, Sara Simões, Felix Bärlocher, Cristina Canhoto
Human-induced salinization of freshwaters constitutes a growing global problem, whose consequences on streams functioning are largely unknown. Climate change projections predict enhanced evaporation, as well as an increase in extreme events and in variability of precipitation. This will result in more frequent, extended and severe drought periods that may aggravate water salinization of streams and rivers. In this study we conducted a microcosm experiment to assess the combined effects of three drought regimes - abrupt (AD), slow (SD) and very slow transition to dryness (VSD) - and three levels of salinization (0, 4, 6 g L-1 NaCl) on microbial-mediated oak leaf decomposition over ten weeks...
February 25, 2019: Science of the Total Environment
Amanda Chaaban, Vinicius Sobrinho Richardi, Alessandra Regina Carrer, Juliana Sperotto Brum, Roger Raupp Cipriano, Carlos Eduardo Nogueira Martins, Mário Antônio Navarro Silva, Cicero Deschamps, Marcelo Beltrão Molento
Lucilia cuprina, known as the Australian blowfly, is of high medico-sanitary and veterinary importance due to its ability to induce myiasis. Synthetic products are the most frequent form of fly control, but their indiscriminate use has selected for resistant populations and accounted for high levels of residues in animal products. This study aimed to assess the effect of essential oil from leaves of Curcuma longa (CLLEO), and its major compound α-phellandrene against L. cuprina L3. An additional goal was to determine the morphological alterations in target organs/tissues through ultrastructural assessment (SEM) and light microscopy, as well as macroscopic damage to cuticle induced by CLLEO...
January 2019: Pesticide Biochemistry and Physiology
Runjie Song, Jinglong Wang, Lu Sun, Yajing Zhang, Zhenghui Ren, Baoyu Zhao, Hao Lu
BACKGROUND: The indolizidine alkaloid-swainsonine is produced by an endophytic fungus Alternaria oxytropis, which was isolated from locoweeds. Swainsonine has many biological activities such as anti-tumorigenic, anti-viral and bacteriostatic. However, the full complement of metabolites produced by Alternaria oxytropis is not known. This study is a chemical analysis of Alternaria oxytropis metabolites, which not only unravels the potential compounds from the fermentation broth but also in which solvent are they extracted, facilitating industrial application...
February 11, 2019: BMC Microbiology
Pilar Andrés, Antoni Rosell-Melé, Ferran Colomer-Ventura, Karolien Denef, M Francesca Cotrufo, Miquel Riba, Josep M Alcañiz
Biochar is a high carbon material resulting from biomass pyrolysis that, when applied to croplands, can increase soil carbon and soil water retention. Both effects are of critical importance in semi-arid regions, where carbon decline and desertification are the main drivers of soil degradation. Since most environmental services provided by soil are mediated by belowground biota, effects of biochar on soil microbial and invertebrate communities must be evaluated under field conditions before its agricultural application can be recommended...
April 10, 2019: Science of the Total Environment
Justin C Parker, Rolf W Scharfbillig, Sara Jones
BACKGROUND: Xerosis (dryness) of the foot is commonly encountered in clinical care and can lead to discomfort, pain, and predisposition to infection. Many moisturizing products are available, with little definitive research to recommend any particular formulation. METHODS: We compared two commonly prescribed moisturizing products from different ends of the price spectrum (sorbolene and 25% urea cream) for their effectiveness in reducing xerosis signs using the Specified Symptom Sum Score...
November 2018: Journal of the American Podiatric Medical Association
LaTina J Watson, Kaitlyn E James, Ida J Hatoum Moeller, Caroline M Mitchell
OBJECTIVES: We surveyed women from a primary care population to assess the prevalence of unreported vulvovaginal symptoms. MATERIALS AND METHODS: A random sample of women aged 18 to 84 years without a diagnosis of vulvovaginitis or vulvodynia in the past year were surveyed anonymously about prevalence and severity of vulvar and vaginal symptoms of itching, burning, irritation, vaginal discharge, vaginal dryness, and vulvovaginal pain in the past month. Women reporting at least 1 moderate-severe symptom were considered symptomatic...
February 7, 2019: Journal of Lower Genital Tract Disease
Tomas Fait, Manuela Sailer, Pedro-Antonio Regidor
Safety concerns or contraindications to the use of hormones have resulted in a rise of the use of herbal medicinal products for the management of menopausal symptoms. The pollen extract Sérélys® represents, due to its ingredients and mode of action, a new and innovative alternative for the management of these symptoms. The aim of the present study was to demonstrate the efficacy and safety of Sérélys® . A prospective, open, observational, and multicentre study was performed on 104 menopausal women. The patients received over 3 months the pollen extract Sérélys® containing the extracts PI82 and GC Fem in a dosage of twice 160 mg extract and 5 mg vitamin E...
February 10, 2019: Gynecological Endocrinology
M T Jewell, M Cameron, J Spears, S L McKenna, M S Cockram, J Sanchez, G P Keefe
Skin lesions are commonly seen in dairy herds and have been associated with animal-, environmental-, and management factors. These lesions are not only a welfare concern, but they also affect profitability. Three areas on the cattle were examined for skin lesions: the hock, knee, and neck. Previous Canadian studies estimating the prevalence of lesions and the risk factors associated with them have not included the Maritime Provinces. In this study, 73 herds in the Maritime Provinces were chosen voluntarily to participate, with both tiestalls (n = 33) and freestalls (n = 40) represented...
February 6, 2019: Journal of Dairy Science
Mark J Hovenden, Sebastian Leuzinger, Paul C D Newton, Andrew Fletcher, Simone Fatichi, Andreas Lüscher, Peter B Reich, Louise C Andresen, Claus Beier, Dana M Blumenthal, Nona R Chiariello, Jeffrey S Dukes, Juliane Kellner, Kirsten Hofmockel, Pascal A Niklaus, Jian Song, Shiqiang Wan, Aimée T Classen, J Adam Langley
Rising atmospheric carbon dioxide concentration should stimulate biomass production directly via biochemical stimulation of carbon assimilation, and indirectly via water savings caused by increased plant water-use efficiency. Because of these water savings, the CO2 fertilization effect (CFE) should be stronger at drier sites, yet large differences among experiments in grassland biomass response to elevated CO2 appear to be unrelated to annual precipitation, preventing useful generalizations. Here, we show that, as predicted, the impact of elevated CO2 on biomass production in 19 globally distributed temperate grassland experiments reduces as mean precipitation in seasons other than spring increases, but that it rises unexpectedly as mean spring precipitation increases...
February 2019: Nature Plants
Hirotaka Tanabe, Motoko Kawashima, Minako Kaido, Reiko Ishida, Tetsuya Kawakita, Kazuo Tsubota
BACKGROUND: To evaluate the safety and efficacy of using a lid hygiene brush prototype to wipe the lid margins with lid hygiene shampoo in subjects with normal meibomian glands. METHODS: Twelve eyes of 6 subjects were all evaluated just before and after wiping lid margins using 1) tap water alone, 2) Eye Shampoo, 3) Eye Brush, or 4) both products, each during a different week. The results after using both products twice daily for 1 month were also evaluated. Wiping efficacy was determined by post-wiping scores for the remaining fluorescein-stained 0...
February 4, 2019: BMC Ophthalmology
Robi N Maamari, Philip L Custer, Michael G Neimkin, Steven M Couch
PURPOSE: To report the surgical technique and functional outcomes of the medial canthoplasty for the treatment of exposure keratopathy. PATIENTS/METHODS: An IRB approved, retrospective review of patients who underwent medial canthoplasty for exposure keratopathy was performed. Patient demographics, reported symptoms, and clinical examination findings were collected and analyzed from pre-operative and follow-up visits. RESULTS: The study included 73 consecutive cases in which the medial canthoplasty was performed in patients with exposure keratopathy...
February 1, 2019: Eye
Yushi Katsuyama, Norihisa Taira, Tatsuya Tsuboi, Masato Yoshioka, Yuri Okano, Hitoshi Masaki
Skin sensitivity is a serious problem for many people, and it can be induced by various factors such as UV irradiation, physical and mental stresses, air pollution, dry air and so on. Skin dryness triggered by UV and dry air is one of the most important causes inducing the development of sensitive skin, and it has been reported that oxidative stress contributes to skin dryness. In this study, we investigated whether treatment with 3-O-laurylglyceryl ascorbate (VC-3LG), which is an amphipathic ascorbic acid derivative, can suppress the development of sensitive skin...
February 2019: Experimental Dermatology
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