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Anna T Crouch
This qualitative grounded theory case study aimed to explore the perceptions of the impact of dyslexia on nursing and midwifery students and of the coping strategies they develop and/or use to help them cope in practice. The questions addressed were: 1. What is the perceived impact of dyslexia on the nursing and midwifery student in clinical practice? 2. How are any difficulties associated with dyslexia managed by the nursing or midwifery student? 3i. What strategies can help and support nursing and midwifery students with dyslexia? 3ii...
January 4, 2019: Nurse Education in Practice
Vishal Sahu, Anant Mohan, Sharmistha Dey
INTRODUCTION: p38 MAPK signaling molecules plays a dual role in cancer, both progression and suppression. Elevated expression of p38α was reported in lung cancer tissue in rat model. Our objective was to explore the concentration of all 4 isoforms of p38MAPK in serum of Non Small Cell Lung Cancer (NSCLC). MATERIAL AND METHODS: The blood samples were collected from 77 NSCLC patients, 52 ethically matched healthy controls and 18 follow up patients were collected as some patients expired and some discontinued the treatment...
February 13, 2019: Experimental and Molecular Pathology
Vojtěch Brlík, Jaroslav Koleček, Malcolm Burgess, Steffen Hahn, Diana Humple, Miloš Krist, Janne Ouwehand, Emily L Weiser, Peter Adamík, José A Alves, Debora Arlt, Sanja Barišić, Detlef Becker, Eduardo J Belda, Václav Beran, Christiaan Both, Susana P Bravo, Martins Briedis, Bohumír Chutný, Davor Ćiković, Nathan W Cooper, Joana S Costa, Víctor R Cueto, Tamara Emmenegger, Kevin Fraser, Olivier Gilg, Marina Guerrero, Michael T Hallworth, Chris Hewson, Frédéric Jiguet, James A Johnson, Tosha Kelly, Dmitry Kishkinev, Michel Leconte, Terje Lislevand, Simeon Lisovski, Cosme López, Kent P McFarland, Peter P Marra, Steven M Matsuoka, Piotr Matyjasiak, Christoph M Meier, Benjamin Metzger, Juan S Monrós, Roland Neumann, Amy Newman, Ryan Norris, Tomas Pärt, Václav Pavel, Noah Perlut, Markus Piha, Jeroen Reneerkens, Christopher C Rimmer, Amélie Roberto-Charron, Chiara Scandolara, Natalia Sokolova, Makiko Takenaka, Dirk Tolkmitt, Herman van Oosten, Arndt H J Wellbrock, Hazel Wheeler, Jan van der Winden, Klaudia Witte, Brad Woodworth, Petr Procházka
Currently, the deployment of tracking devices is one of the most frequently used approaches to study movement ecology of birds. Recent miniaturisation of light-level geolocators enabled studying small bird species whose migratory patterns were widely unknown. However, geolocators may reduce vital rates in tagged birds and may bias obtained movement data. There is a need for a thorough assessment of the potential tag effects on small birds, as previous meta-analyses did not evaluate unpublished data and impact of multiple life-history traits, focused mainly on large species and the number of published studies tagging small birds has increased substantially...
February 16, 2019: Journal of Animal Ecology
Mary Jean Walker, Justin Bourke, Katrina Hutchison
Personalised medicine (PM) has been discussed as a medical paradigm shift that will improve health while reducing inefficiency and waste. At the same time, it raises new practical, regulatory, and ethical challenges. In this paper, we examine PM strategies epistemologically in order to develop capacities to address these challenges, focusing on a recently proposed strategy for developing patient-specific models from induced pluripotent stem cells (iPSCs) so as to make individualised treatment predictions. We compare this strategy to two main PM strategies-stratified medicine and computational models...
February 15, 2019: Theoretical Medicine and Bioethics
Kathryn Polak, Sydney Kelpin, Mishka Terplan
Substance use during pregnancy is common, costly and associated with maternal and newborn health consequences. Assessment of substance use should be integrated into prenatal care. Substance use identification methods include patient interview, screening instruments, and biological testing. In this review, we critically evaluate screening and testing for substance use during pregnancy, highlighting the benefits and barriers of integrated assessment into prenatal care. We also discuss the limitations and negative consequences that should be considered when implementing screening and/or testing procedures...
February 5, 2019: Seminars in Fetal & Neonatal Medicine
Kishor Patwardhan, B S Prasad, Anam Aftab, Varsha Raghunath More, Shriram S Savrikar
This paper examines the scenario of research orientation in Ayurveda educational institutions of India. We demonstrate through the data obtained by searching the SCOPUS that the actual research output by these institutions is not very significant in terms of number of publications. While a lack of research expertise and infrastructure is one contributing factor to this status, a lack of questioning attitude is more crucial one. Mushrooming of new colleges, laxity in regulations, corruption, lack of atmosphere for ethical and quality research make the problem more complex...
February 12, 2019: Journal of Ayurveda and Integrative Medicine
Iori Kisu, Yu Liu, Gaowen Chen, Min Jong Song, Cherry Yin-Yi Chang, Tan Hak Koon, Kouji Banno, Daisuke Aoki
Uterus transplantation (UTx) is now a possible approach for women with absolute uterine factor infertility to deliver a child, following the first successful delivery by Brännström et al. in Sweden in September 2014. This remarkable achievement attracted major attention worldwide and caused many countries to prepare for UTx, including countries in Asia. To date, three groups have performed UTx in humans in Asia, and many others are aiming for the clinical application of UTx with accumulation of basic experimental data...
February 14, 2019: Journal of Clinical Medicine
Kimberly A Finlayson, Frederic D L Leusch, Jason P van de Merwe
Chemical contaminants have been found in the tissues of sea turtles from all over the world; however, very little is known about the effects. Recently, in vitro alternatives to live animal testing have been applied to sea turtles due to their ethical and practical benefits. While primary skin fibroblasts have been established for several species of sea turtle, cells from internal organs are lacking, though they may be more relevant due to the well documented accumulation of contaminants within internal tissues...
February 4, 2019: Science of the Total Environment
Kimberly A Finlayson, Frederic D L Leusch, Colin J Limpus, Jason P van de Merwe
Chemical contaminants are known to accumulate in marine megafauna globally, but little is known about how this impacts animal health. In vitro assays offer an ethical, reproducible and cost-effective alternative to live animal toxicity testing on large, long-lived or threatened species, such as sea turtles. However, using a cell culture from a single animal raise the question of whether the toxicity observed adequately represents the toxicity in that species. This study examined variation in the cytotoxic response of primary skin fibroblasts established from seven green (Chelonia mydas) and five loggerhead (Caretta caretta) sea turtles...
February 12, 2019: Ecotoxicology and Environmental Safety
Gretchen L Birbeck, Virginia Bond, Valerie Earnshaw, Musah Lumumba El-Nasoor
Health-related stigma remains a major barrier to improving health and well-being for vulnerable populations around the world. This collection on stigma research and global health emerged largely as a result of a 2017 meeting on the "The Science of Stigma Reduction" sponsored by the US National Institutes of Health (NIH). An overwhelming consensus at the meeting was reached. It was determined that for stigma research to advance further, particularly to achieve effective and scalable stigma reduction interventions, the discipline of stigma research must evolve beyond disease-specific investigations and frameworks and move toward more unified theories of stigma that transcend individual conditions...
February 15, 2019: BMC Medicine
Jean-Marc Josset, Florian Lavoyer, Patricia Pâme
Since the French National Authority for Health first promoted the ?ethics of care-giving? at the end of 2012, the humanization of home care remains a challenging topic. In order to handle the difficulties of managing a team of caregivers faced with strenuous work, practice exchange groups are often set up. However, there tends to be very little feedback on the implementation process. By studying the accounts and comments of caregivers in the town of Bouguenais throughout a training session undertaken in the year 2017-2018, we enrich this theoretical proposal with the pitfalls, stages, and discoveries of a concrete experiment...
January 18, 2019: Recherche en Soins Infirmiers
Anne-Blandine Caire
Today, cryogenics is a reality. It is a technique for the preservation of bodies, it is not authorized by French law but is expanding in the United States and other states. It is sometimes regarded as funerary law, while it is conceived by its defenders as a precondition for future revivification. The ethical and legal questions it raises are numerous and symptomatic of the emergence of an existential right.
December 18, 2018: Journal International de Bioéthique et D'éthique des Sciences
Sandrine de Montgolfier, Gerard Bonhoure
Considering the importance of socio-scientific-issues, it has become a necessity to associate teaching sciences and ethics. So, it is relevant to identify tracks which could make this link possible and efficient. This must be done to meet a social expectation which requires that every citizen should be able to take decisions in a complex environment associating scientific knowledge with history, philosophy, economy. The following text relies on conferences and discussions which occured in 2014 on the relation between science education and ethical issues in the secondary school...
April 2018: Journal International de Bioéthique et D'éthique des Sciences
Sanjay Kalra, Gagan Priya, Emmy Grewal, Than Than Aye, B K Waraich, Tint SweLatt, Touch Khun, Menh Phanvarine, Sun Sutta, Uditha Kaush, Manilka, Sundeep Ruder, Bharti Kalra
From its earliest days, Buddhism has been closely intertwined with the practice of medicine, both being concerned in their own way in the alleviation and prevention of human suffering. However, while the connection between Buddhism and healthcare has long been noted, there is scarce literature on how Buddhist philosophy can guide health-care practitioners in their professional as well as personal lives. In the sutras, we find analogies that describe the Buddha as a doctor, knowledge of Dharma as the treatment, and all lay people as patients...
November 2018: Indian Journal of Endocrinology and Metabolism
Saravanakumar Jeevanandam, K M Prathibha
Introduction: A bidirectional relationship between testosterone and obesity is explained by the hypogonadal obesity cycle and evidence from reports stating that weight loss leads to increased testosterone levels. There is an alarming rise in the prevalence of obesity among children and adolescents. The objectives of the present study were to measure the 2D:4D ratio of adolescent students and study its association with neck circumference (NC). Materials and Methods: After obtaining ethical clearance, the study was conducted on 168 adolescents pursuing their undergraduate education in a South Indian university...
November 2018: Indian Journal of Endocrinology and Metabolism
Caterina Cinel, Davide Valeriani, Riccardo Poli
Recent advances in neuroscience have paved the way to innovative applications that cognitively augment and enhance humans in a variety of contexts. This paper aims at providing a snapshot of the current state of the art and a motivated forecast of the most likely developments in the next two decades. Firstly, we survey the main neuroscience technologies for both observing and influencing brain activity, which are necessary ingredients for human cognitive augmentation. We also compare and contrast such technologies, as their individual characteristics (e...
2019: Frontiers in Human Neuroscience
Jodi Berger Cardoso, Kalina Brabeck, Dennis Stinchcomb, Lauren Heidbrink, Olga Acosta Price, Óscar F Gil-García, Thomas M Crea, Luis H Zayas
Between October 2013 and July 2016, over 156,000 children traveling without their guardians were apprehended at the US-Mexico border and transferred to the care of the Office of Refugee Resettlement (ORR). During that same period, ORR placed over 123,000 unaccompanied migrant youth-predominantly from Central America-with a parent or other adult sponsor residing in the US. Following placement, local communities are tasked with integrating migrant youth, many of whom experience pre- and in-transit migration traumas, family separation, limited/interrupted schooling, and unauthorised legal status, placing them at heightened risk for psychological distress, academic disengagement, maltreatment, and human trafficking...
2019: Journal of Ethnic and Migration Studies
Waleed Alharbi, Jennifer Cleland, Zoe Morrison
Objective: Adverse events which result from medication errors are considered to be one of the most frequently encountered patient safety issues in clinical settings. We undertook a qualitative investigation to identify and explore factors relating to medication error in an adult oncology department in Saudi Arabia from the perspective of healthcare professionals. Methods: This was a qualitative study conducted in an adult oncology department in Saudi Arabia. After obtaining required ethical approvals and written consents from the participants, semi-structured interviews and focus group discussions were carried out for data collection...
February 2019: Saudi Pharmaceutical Journal: SPJ: the Official Publication of the Saudi Pharmaceutical Society
Abdulaziz M Albaker, Fahad D Alosaimi
Objectives: To examine the knowledge and attitude towards dentist-industry relationship including accepting gifts, influence on decisions, and accuracy of given information among dentists working in Saudi Arabia. In addition, to examine the association of such knowledge and attitude of dentists' behavior with industry, including sorts of interaction and accepting industrial gifts. Methods: A cross-sectional study was conducted among dental practitioners working in the private and governmental hospitals located in the various regions of Saudi Arabia...
February 2019: Saudi Pharmaceutical Journal: SPJ: the Official Publication of the Saudi Pharmaceutical Society
Ahmet Can Bilgin, Sevgi Timbil, Cemal Huseyin Guvercin, Sema Ozan, Semih Semin
AIM: We aimed to receive the opinions of the preclinical medical students on medical ethics education, and to present some suggestions for the education program. METHODS: Focus group discussions were held with third-grade medical students. The analyses were implemented using Creswell's six-step qualitative data analysis. RESULTS: During the data analysis, themes with the following titles were identified: necessity of the education, content, education methods, assessment, participation, contribution of the education, moving to clinical training and suggestions...
June 2018: Acta Bioethica
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