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Hypertension management in black population

Sameer Arora, George A Rick Stouffer, Anna Kucharska-Newton, Arman Qamar, Muthiah Vaduganathan, Ambarish Pandey, Deborah S Porterfield, Ron Blankstein, Wayne D Rosamond, Deepak Bhatt, Melissa C Caughey
BACKGROUND: Sex differences are known to exist in the management of older patients presenting with acute myocardial infarction (AMI). Few studies have examined the incidence and risk factors of AMI among young patients, or whether clinical management differs by sex. METHODS: The Atherosclerosis Risk in Communities (ARIC) Surveillance study conducts hospital surveillance of AMI in 4 US communities (MD, MN, MS, and NC). AMI was classified by physician review, using a validated algorithm...
November 11, 2018: Circulation
Douglas Barthold, Geoffrey Joyce, Whitney Wharton, Patrick Kehoe, Julie Zissimopoulos
BACKGROUND: Antihypertensive treatments have been shown to reduce the risk of Alzheimer's disease (AD). The renin-angiotensin system (RAS) has been implicated in AD, and thus RAS-acting AHTs (angiotensin converting enzyme inhibitors (ACEIs), and angiotensin-II receptor blockers (ARBs)) may offer differential and additional protective benefits against AD compared with other AHTs, in addition to hypertension management. METHODS: In a retrospective cohort design, we examined the medical and pharmacy claims of a 20% sample of Medicare beneficiaries from 2007 to 2013, and compared rates of AD diagnosis for 1,343,334 users of six different AHT drug treatments, 65 years of age or older (4,215,338 person-years)...
2018: PloS One
Lesley A Inker, Morgan E Grams, Andrew S Levey, Josef Coresh, Massimo Cirillo, John F Collins, Ron T Gansevoort, Orlando M Gutierrez, Takayuki Hamano, Gunnar H Heine, Shizukiyo Ishikawa, Sun Ha Jee, Florian Kronenberg, Martin J Landray, Katsuyuki Miura, Girish N Nadkarni, Carmen A Peralta, Dietrich Rothenbacher, Elke Schaeffner, Sanaz Sedaghat, Michael G Shlipak, Luxia Zhang, Arjan D van Zuilen, Stein I Hallan, Csaba P Kovesdy, Mark Woodward, Adeera Levin
RATIONALE & OBJECTIVE: Chronic kidney disease (CKD) is complicated by abnormalities that reflect disruption in filtration, tubular, and endocrine functions of the kidney. Our aim was to explore the relationship of specific laboratory result abnormalities and hypertension with the estimated glomerular filtration rate (eGFR) and albuminuria CKD staging framework. STUDY DESIGN: Cross-sectional individual participant-level analyses in a global consortium. SETTING & STUDY POPULATIONS: 17 CKD and 38 general population and high-risk cohorts...
February 2019: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
Onur Asan, Farion Cooper Ii, Sneha Nagavally, Rebekah J Walker, Joni S Williams, Mukoso N Ozieh, Leonard E Egede
BACKGROUND: Emerging health technologies are increasingly being used in health care for communication, data collection, patient monitoring, education, and facilitating adherence to chronic disease management. However, there is a lack of studies on differences in the preference for using information exchange technologies between patients with chronic and nonchronic diseases and factors affecting these differences. OBJECTIVE: The purpose of this paper is to understand the preferences and use of information technology for information exchange among a nationally representative sample of adults with and without 3 chronic disease conditions (ie, cardiovascular disease [CVD], diabetes, and hypertension) and to assess whether these preferences differ according to varying demographic variables...
October 18, 2018: Journal of Medical Internet Research
Dulaney A Wilson, Braxton B Wannamaker, Angela M Malek, Anbesaw W Selassie
INTRODUCTION: Cardiovascular comorbidities of epilepsy such as hypertension, hyperlipidemia, and diabetes are associated with myocardial infarction (MI). Little data on the development of subsequent cardiovascular disease (CVD) in persons with epilepsy (PWE) are available, with inconsistent findings regarding the association between epilepsy and subsequent MI. A higher risk of MI among adults (without prior MI) following epilepsy diagnosis compared with that among controls was hypothesized...
November 2018: Epilepsy & Behavior: E&B
Hatem A Wafa, Charles D A Wolfe, Anthony Rudd, Yanzhong Wang
BACKGROUND: As the average life expectancy increases, more people are predicted to have strokes. Recent studies have shown an increasing incidence in certain types of cerebral infarction. We aimed to estimate time trends in incidence, prior risk factors, and use of preventive treatments for ischaemic stroke (IS) aetiological subtypes and to ascertain any demographic disparities. METHODS AND FINDINGS: Population-based data from the South London Stroke Register (SLSR) between 2000 and 2015 were studied...
October 2018: PLoS Medicine
Nasheeta Peer, Yusentha Balakrishna, Anniza de Villiers, Pamela Naidoo
AIMS: To describe the distribution and examine the associations of diabetes, hypertension and hypercholesterolaemia across and within population groups, gender and body mass index (BMI) categories. METHODS: This national cross-sectional study was conducted in 2013 among ≥18-year-old black African, coloured, white and Indian adults self-selected for screening. Data collection included self-reported behavioural risk factors and clinical measurements comprising blood pressure, anthropometry and point-of-care random blood glucose and cholesterol assessments...
2018: PloS One
Viktor Dombrovskiy, Ephrem O Olweny
OBJECTIVE: To describe population-wide utilization rates and outcomes of percutaneous nephrolithotomy (PCNL) in the management of pediatric upper urinary tract calculi (UUTC). PATIENTS AND METHODS: Patients <18 years with a diagnosis of UUTC, who underwent PCNL between 2001 and 2014 were identified from the National Inpatient Sample database. Annual PCNL rates, based on the at-risk population for each year, were estimated, and change in utilization rate was analyzed using negative binomial regression...
October 2018: Journal of Endourology
Elizabeth L Tung, Tyrone A Johnson, Yolanda O'Neal, Althera M Steenes, Graciela Caraballo, Monica E Peek
BACKGROUND: Community violence is an important social determinant of health in many high-poverty, urban communities. OBJECTIVE: The purpose of this study was to explore and characterize self-described experiences of community violence among adults with chronic health conditions. DESIGN: Qualitative study design was implemented in 2017 using in-depth, semi-structured focus groups and interviews; data were collected from two clinical sites located in geographic epicenters of high violent crime in Chicago...
November 2018: Journal of General Internal Medicine
Katherine A Treiman, Stephanie Teixeira-Poit, Lei Li, Mariam Tardif-Douglin, Jean Gaines, Thomas Hoerger
PURPOSE: Evaluate the Centers for Medicare & Medicaid Incentives for Prevention of Chronic Diseases (MIPCD) program in terms of participant satisfaction and self-reported program impact. DESIGN: Participant survey (mail/telephone follow-up), English and Spanish (N = 2274). SETTINGS: Ten states in MIPCD program. PARTICIPANTS: Medicaid beneficiaries. INTERVENTION: Incentive-based health promotion programs targeting diabetes prevention and management, smoking cessation, and weight, hypertension, and cholesterol management...
January 1, 2018: American Journal of Health Promotion: AJHP
Valy Fontil, Reena Gupta, Nathalie Moise, Ellen Chen, David Guzman, Charles E McCulloch, Kirsten Bibbins-Domingo
BACKGROUND: Nearly half of Americans with diagnosed hypertension have uncontrolled blood pressure (BP) while some integrated healthcare systems, such as Kaiser Permanente Northern California, have achieved control rates upwards 90%. METHODS AND RESULTS: We adapted Kaiser Permanente's evidence-based treatment protocols in a racially and ethnically diverse population at 12 safety-net clinics in the San Francisco Health Network. The intervention consisted of 4 elements: a hypertension registry, a simplified treatment intensification protocol that included fixed-dose combination medications containing diuretics, standardized BP measurement protocol, and BP check visits led by registered nurse and pharmacist staff...
July 2018: Circulation. Cardiovascular Quality and Outcomes
Melissa Maritz, Carla M T Fourie, Johannes M Van Rooyen, Aletta E Schutte
AIMS: Black populations from sub-Saharan Africa have a high prevalence of cardiovascular disease, which places significant strain on public health systems. Aortic stiffness is a prominent risk factor for cardiovascular disease development. We reported earlier that excessive alcohol use predicts aortic stiffness. However, we require a better understanding of other biomarkers involved in stiffness development, beyond alcohol use. Therefore, we determined which biomarkers (metabolic, inflammatory, endothelial activation and oxidative stress) relate to aortic stiffness in young and older black South Africans, self-reporting no alcohol-use...
August 2018: Diabetes Research and Clinical Practice
Dike B Ojji, Neil Poulter, Albertino Damasceno, Karen Sliwa, Wynand Smythe, Nicky Kramer, Motasim Badri, Veronica Francis, Akinyemi Aje, Felix Barasa, Anastase Dzudie, Erika Jones, Shehu S Kana, Pindile Mntla, Charles Mondo, Okechukwu Ogah, Elijah N Ogola, Gboyega Ogunbanjo, Ikechi Okpechi, Gabriel Shedul, Mahmoud U Sani, Grace Shedul, Bongani M Mayosi
BACKGROUND: Current hypertension guidelines recommend the use of combination therapy as first-line treatment or early in the management of hypertensive patients. Although there are many possible combinations of blood pressure(BP)-lowering therapies, the best combination for the black population is still a subject of debate because no large randomized controlled trials have been conducted in this group to compare the efficacy of different combination therapies to address this issue. METHODS: The comparison of 3 combination therapies in lowering BP in the black Africans (CREOLE) study is a randomized single-blind trial that will compare the efficacy of amlodipine plus hydrochlorothiazide versus amlodipine plus perindopril and versus perindopril plus hydrochlorothiazide in blacks residing in sub-Saharan Africa (SSA)...
August 2018: American Heart Journal
Rebecca Robbins, Azizi Seixas, Girardin Jean-Louis, Sairam Parthasarathy, David M Rapoport, Gbenga Ogedegbe, Joseph A Ladapo
STUDY OBJECTIVES: Sleep apnea is associated with hypertension, and treatment may improve outcomes. We examine national burden of sleep apnea, rates of sleep apnea treatment, and whether racial/ethnic disparities exist among patients with hypertension. METHODS: Data from the National Ambulatory Medical Care Survey/National Hospital Ambulatory Medical Care Survey (NAMCS/NHAMCS), 2005-2012, were analyzed (N = 417,950). We identified hypertension patient visits where sleep apnea diagnosis or complaint was recorded...
2018: PloS One
Lia Thieme Oikawa Zangirolani, Daniela de Assumpção, Maria Angélica Tavares de Medeiros, Marilisa Berti Azevedo Barros
OBJECTIVES: Evaluate the prevalence of self-reported hypertension in adults aged 20 to 59 years as well as identify associated factors, the use of health services and disease control practices according to the possession or not of a private healthcare plan. METHODS: A population-based, cross-sectional study was conducted in the city of Campinas, Brazil, involving 957 adults. RESULTS: The prevalence of self-reported hypertension was 14.1%, with greater frequencies found among women, individuals aged ≥ 40 years, those who declared their skin color to be black, those with less schooling, those who did not practice active leisure activities, ex-smokers, overweight or obese individuals and those who rated their own health as not being excellent/very good...
April 2018: Ciência & Saúde Coletiva
Gbolahan O Ogunbayo, Katrina Bidwell, Naoki Misumida, Le Dung Ha, Ahmed Abdel-Latif, Claude S Elayi, Susan Smyth, Adrian W Messerli
BACKGROUND: Studies have reported sex differences in the management of patients with acute myocardial infarction (AMI) in the general population. This observational study is designed to evaluate whether sex differences exist in the contemporary management of human immunodeficiency virus (HIV) patients admitted for diagnosis of AMI. HYPOTHESIS: There is no difference in management of HIV patients with AMI. METHODS: Using the National Inpatient Sample database, we identified patients with a primary diagnosis of AMI and a secondary diagnosis of HIV...
April 2018: Clinical Cardiology
Aisha James, Seth A Berkowitz, Jeffrey M Ashburner, Yuchiao Chang, Daniel M Horn, Sandra M O'Keefe, Steven J Atlas
BACKGROUND: Healthcare systems use population health management programs to improve the quality of cardiovascular disease care. Adding a dedicated population health coordinator (PHC) who identifies and reaches out to patients not meeting cardiovascular care goals to these programs may help reduce disparities in cardiovascular care. OBJECTIVE: To determine whether a program that used PHCs decreased racial/ethnic disparities in LDL cholesterol and blood pressure (BP) control...
April 2018: Journal of General Internal Medicine
Nomsa Musemwa, Crystal A Gadegbeku
PURPOSE OF REVIEW: African Americans are over-burdened with hypertension resulting in excess morbidity and mortality. We highlight the health impact of hypertension in this population, review important observations regarding disease pathogenesis, and outline evidence-based treatment, current treatment guidelines, and management approaches. RECENT FINDINGS: Hypertension accounts for 50% of the racial differences in mortality between Blacks and Whites in the USA. Genome-wide association studies have not clearly identified distinct genetic causes for the excess burden in this population as yet...
October 28, 2017: Current Cardiology Reports
Ioanna Gouni-Berthold, Ruth Hanssen, Lisa Ravarani, Heiner K Berthold
BACKGROUND: In patients with diabetes mellitus (DM) there is a clear association between blood pressure (BP) levels and macrovascular and microvascular complications. However, the BP targets that need to be achieved for optimal outcomes remain controversial. METHODS: The purpose of this narrative review is to discuss BP targets and management in patients with DM. The subject of elevated heart rate, which has been associated with mortality in many populations, and which is observed in some patients with DM will also be addressed...
2017: Current Pharmaceutical Design
Nabilah F Lari, Michael R DeBaun, Samuel A Oppong
Sickle cell disease (SCD) is one of the most common hemoglobinopathy, affecting a considerable proportion of black populations of African origin, Middle East and in the Indian sub-continent. Women with SCD are more likely to experience adverse pregnancy and delivery outcomes. Hypertensive diseases in pregnancy such as preeclampsia and eclampsia are more common in women with sickle cell disease. Areas covered: This review examined the influence of hypertension and SCD in pregnancy, and provides the preliminary evidence that the traditional systolic and diastolic blood pressure thresholds for hypertensive disorders such as pre-eclampsia and eclampsia may require reassessment in pregnant women with SCD...
November 2017: Expert Review of Hematology
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